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Diagnosis and treatment of common oral lesions found in the elderly.

A wide variety of oral lesions are recognized in the geriatric patient. The most common lesions include neoplasia, immunologic based mucosal disease, hematological disorders, oral manifestation of systemic disease, and conditions characterized by oral or facial pain. Diagnostic and treatment considerations for leukoplakia, carcinoma, metastatic disease, candidiasis, herpes zoster, plasmacytoma, myeloma, lymphoma, several of the more common vesiculoulcerative mucosal diseases and idiopathic burning mouth syndrome are presented.

Aged↗

Changing oral care needs in the United States: the continuing need for oral medicine.

OBJECTIVE: The purpose of this article is to provide oral care providers evidence of oral conditions and medical compromise that is impacting the oral health and oral health needs of the public. DESIGN: Data were analyzed based on current epidemiologic data, derived in large part from the Health and Nutrition Examination Surveys, the National Center for Health Statistics, National Health Interview Survey Series 1994-1997; American Cancer Society, National Cancer Institute Surveillance Examination and End Results data base, Morbidity and Mortality Weekly Reports, peer-reviewed publications, and surveys of oral medicine-related disorders. RESULTS: Millions of Americans have medical conditions that complicate their oral health care. Oral health problems associated with age, medical health and treatment, and institutional setting are increasing. Chronic orofacial pain, persistent oral soft tissue lesions, and salivary gland and chemosensory disorders are common problems of modern society. CONCLUSIONS: Evidence suggests that the next decade will bring a significantly increased demand for diagnosis and management of patients with oral conditions and patients with oral manifestations of systemic conditions, and an increase in general oral care needs of patients who are medically compromised. These increasing demands should be reflected in dental education and continuing education.

Aged↗

The oral cavity in Crohn's disease.

We assessed the utility of expert oral examination as a part of the diagnostic evaluation of patients with suspected Crohn's disease. Of 45 patients with newly diagnosed CD, 25 had been examined by a dentist. Twelve (48%) of these had oral CD lesions. Mucosal tags constituted the most frequent form of oral lesion (8/12). Of 8 oral biopsy specimens, 6 (75%) contained non-caseating granulomas. Patients with oral CD had more oral symptoms, presented for diagnosis sooner, and were more likely to have other upper gastrointestinal inflammation than those without oral lesions. Oral manifestations of CD are common in children; therefore, expert oral examination may be useful during diagnostic evaluation of children with suspected inflammatory bowel disease.

Adolescent↗

Gingival enlargement as a diagnostic indicator in leukaemia. Case report.

The acute leukaemias are a group of neoplastic diseases that are characterized by proliferation of immature white cells in the bone marrow and/or blood and are often associated with severe leukopenia, anaemia and thrombocytopenia. Oral manifestations are more common in patients with acute leukaemia. Oral bleeding, gingival enlargement, ulceration and infection in patients with leukaemia have been described. Leukaemic infiltrates in the gingivae are commonly seen in acute monocytic leukaemia. A case of acute monocytic leukaemia in a 34-year-old female who reported with gingival enlargement is presented here. The role of oral lesions as a diagnostic indicator is discussed.

Adult↗

Acute leukaemia presenting as oral ulceration to a dental emergency service.

Leukaemia is a neoplastic disease characterized by an excessive proliferation of immature white blood cells and their precursors. Oral lesions may be the presenting feature of acute leukaemias, which can be rapidly fatal if left untreated. This report describes the case of a 22-year-old female who presented to a dental emergency department with oral manifestations of acute leukaemia. It outlines the role of oral lesions in the diagnosis of acute leukaemias and emphasizes the importance of immediate referral by general dental practitioners.

Acute Disease↗

Kaposi's sarcoma in patients with AIDS.

All health care providers must become increasingly aware of the early signs and symptoms of AIDS as KS frequently appears in the head, neck, and oral regions. Dentists are responsible for recognizing these lesions, especially the early lesions, providing dental treatment as appropriate, and for referring patients with AIDS for counseling and treatment that cannot be provided in their office. Early detection of KS is particularly important for patients receiving dental treatment. The dentist must be careful not to further compromise the patient's health by extensive or stressful dental treatment and to prevent intraoperative or postoperative complications. Early supportive and palliative care will improve the patient's prognosis. Dental care will help HIV-infected patients and those with AIDS to avoid caries and periodontal disease. In addition, regular dental care will enable the dentist in the early diagnosis of the disease's oral manifestations, such as candidiasis, hairy leukoplakia, KS, or other oral opportunistic infection. Treatment of these conditions can significantly improve the patients' quality of life and their chances for survival. When universal precautions are used for infection control in the dental office there is no reason that comprehensive dental care cannot be provided for HIV infected patients--both for those that we know are infected and for those that are infected and we don't know about.

Acquired Immunodeficiency Syndrome↗

Various patterns of oral mucosa candidiasis treatment in HIV patients.

Oral cavity is the site of numerous HIV infection manifestations. Oral mucosa candidiasis is the most common one. It may be the earliest sign of the underlying disease. Long lasting observations give evidence that antiretroviral therapy is beneficial also in the cases of this opportunistic infection because it reduces both the number and severity of relapses, however, the prolongation of the patients' survival time creates the need of antifungal therapy prolongation, and thorough observation of its effectiveness and methods. We decided to analyze the influence of antiretroviral therapy with at least three drugs on the development of oral mucosa candidiasis in the out- and inpatients of the Jagiellonian University Medical College Clinic of Infectious Diseases (or Outpatient Clinic) in Cracow. The study was carried out in 75 patients with confirmed HIV infection. We have shown a decrease in the number of fungi present in the oral cavity in patients under antiretroviral treatment as well as higher susceptibility to fluconazole.

AIDS-Related Opportunistic Infections↗

Dental-care experiences of people living with HIV/AIDS in Aotearoa New Zealand.

Previous surveys of people living with HIV/AIDS suggest that such persons may have difficulty in securing dental care and that some dentists would prefer to refer such individuals. This study aimed to assess the experiences of people living with HIV/AIDS in Aotearoa New Zealand in obtaining and undergoing dental treatment. Survey forms were distributed through organisations working with people with HIV/AIDS. Fifty-seven questionnaires were analysed. The majority of respondents were gay white males. Seventy-five percent of participants felt that dental care was important, or very important, and 37 percent had increased the frequency of visits to the dentist since being diagnosed as HIV-positive. Forty-two (74 percent) participants had disclosed their HIV status to their dentists. Of this group, the majority had experienced either supportive or sympathetic reactions. Of those who concealed their status, 31 percent feared rejection by the dental practitioner, and 31 percent felt the dentist was taking adequate precautions and that there was no need to volunteer information on HIV status. Only three people reported denial of treatment on the grounds of their HIV status. An additional two people were immediately referred on by their practitioner after disclosure. Almost half the participants had changed dentists after they were diagnosed as HIV-positive. The main reasons stated included cost of treatment, fear of breach of confidentiality, or shifting to a new centre. Even though 33 percent received dental care in a hospital environment, 63 percent suffered systemic manifestations of HIV-infection, and 51 percent had oral manifestations.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy.

A cross-sectional study examining oral manifestations was carried out in HIV-infected patients of a general HIV-specialized unit to provide prevalence data on oral lesions and periodontal diseases. The occurrence of oral lesions was correlated with demographic and clinical characteristics, immunologic and virologic parameters. Among 139 patients 86% presented any oral lesions with a prevalence of 76% of any periodontal diseases. Most periodontal lesions were classified as conventional gingivitis (28%) or periodontitis (30%). Dental plaque formation was associated with a higher prevalence of periodontal diseases (p = 0.01) and periodontal inflammation scores were higher in patients with more reduced CD4-counts (p = 0.03). Prevalence for HIV-specific oral lesions was 29% with a proportion of 9% of linear gingival erythema (LGE), 3.6% of necrotizing and ulcerative gingivitis (NUG) or periodontitis (NUP), 7% of oral candidiasis, 3.6% of oral hairy leucoplakia (OHL) and single other lesions. HIV-specific lesions (NUG/NUP, oral candidiasis and OHL) were found predominantly in patients with advanced immunosuppression and elevated viral load. Compared with data of oral diseases of the pre-HAART era prevalence of HIV-specific lesions was markedly reduced. Especially frequently known lesions such as oral candidiasis and OHL were less common seen. We noticed a shift of prevalence towards periodontal diseases. Lack of oral hygiene determined by plaque formation and reduced CD4-counts with pronounced periodontal inflammation can be seen as risk factors for periodontal disease. Overall high prevalence of manifestations underlines the importance of oral examination for the general practitioner and visits by oral specialists should become a routine procedure in HIV-patients care.

Adult↗

Orofacial manifestations in primary immunodeficiencies: T lymphocyte defects.

The orofacial manifestations of 10 non-HIV-infected children with primary defects of cell mediated immunity are reported. Oral candidiasis was observed in 80% of patients, with oral ulceration present in 50%. Other oral manifestations included enamel hypoplasia, angular stomatitis, oral purpura and recurrent herpetic infection.

Adolescent↗

Multicentric reticulohistiocytosis.

A case of multicentric reticulohistiocytosis with prominent oral manifestations is described. The case is presented to emphasize the oral involvement since there appear to be no reports of this entity in the dental literature.

Adult↗

Oral symptoms in bulimia nervosa. A survey of 34 cases.

Bulimia nervosa is increasingly recognized as an eating disorder with significant medical and dental complications, including increased caries rate, thermal hypersensitivity, enamel erosion, xerostomia, and parotid gland hypertrophy. This article reviews the oral manifestations in bulimia nervosa and presents a questionnaire study of oral symptoms in 34 women with bulimia nervosa. Twenty-three (68%) of the subjects reported dental symptoms, such as hypersensitive teeth (47%), tooth pain (18%), dental fractures (6%), and subjectively increased caries rate (29%). Twelve women (35%) reported dry mouth or dry eyes as a daily experience, and 10 (29%) reported intermittent parotid gland swelling. To the author's knowledge, this is the first report that evaluates the frequency of subjectively experienced oral symptoms in bulimia nervosa.

Adolescent↗

The Surgeon General's report on oral health: implications for research and education.

The surgeon general's report on oral health ("Oral Health in America: A Report of the Surgeon General"), which was released May 25, highlights the bidirectional interactions between oral and systemic health. Systemic conditions with oral manifestations include diabetes, hereditary disease, joint disease, HIV and osteoporosis. Oral disease can exacerbate certain systemic conditions, such as diabetes, respiratory disease, vascular disease and preterm low-birth weight. While a number of interactions have been identified, additional research is needed to evaluate disease pathogenesis and therapeutic interventions. Further, emphasis should be placed on educating patients, dental and medical students, and dentists and physicians regarding the importance of these relationships. These findings place oral health in the perspective of systemic health, and suggest that the dental and medical profession will develop even closer linkages in the future.

Dental Research↗

The effectiveness of a dental/dietitian team in the assessment of bulimic dental health.

Individuals with bulimia nervosa have been found to experience a variety of dental complications. Because of purging behaviors and erratic food consumption, the oral manifestations of bulimia frequently include irreversible enamel erosion, xerostomia, and oral mucosal irritation. A pilot study was conducted to determine the effectiveness of the dental/dietitian team in assessing the dental health of individuals with bulimia. Control and bulimic subjects were compared. The results demonstrated a significantly different (p less than .05) intake of folacin-412 micrograms in controls compared with 207 micrograms in bulimic subjects. Control subjects were found to have significantly greater (p less than .05) amounts of calculus deposits on teeth; however, subjects with bulimia demonstrated a lower (p less than .05) saliva pH. We conclude that the collaborative effort of the dental/dietitian team was useful in the assessment of dental health. The team approach may also help to identify clients with bulimia and facilitate therapy.

Adult↗