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PubMed2000

[Prevalence of Chlamydia infections in breeding sows and their importance in reproductive failure].

To investigate the prevalence of chlamydial infection and their significance for reproductive disorders in sow breeding herds in Germany, blood samples of 1493 pigs were taken for a serological survey by enzyme-linked-immunosorbent-assay (ELISA). Antibodies to Chlamydiae were found in 33% of the samples, in all herds investigated responders could be detected. The rate of seropositive animals in different farms varied from 4.3% to 72.7%. The percentage of positive responders in the farms correlated positively with the occurrence of MMA-syndrome (mastitis, metritis, agalactia), return to oestrus and diseases of the piglets. Also these herds showed less weaned piglets per sow and litter. Comparison of seronegative and seropositive sows within single farms revealed also worse reproductive data for seropositive sows. A significant relationship could be found between farms with a high quota of sero-positive sows and poor hygiene status as well as poultry keeping. As a second step 124 cervical swabs and 9 aborted piglets were investigated for chlamydial antigen by capture-ELISA and polymerase chain reaction (PCR). Using the capture-ELISA for investigation only 3 probes with chlamydial antigen could be detected, however, examination by the more sensible PCR gave positive results in 50% of the probes. 20% of the PCR-positive animals were clinically healthy sows, 80% of the PCR-positive probes originated from sows with reproductive disorders. A significant relationship could be shown between PCR-positive probes and the incidence of abortion and litters with stillborn piglets and piglets with low viability. Swabs from 93 of the 124 sows were investigated as well for other bacterial pathogens of reproductive disorders. A high degree of micro-organisms of different species could be detected in 70% of the samples of sows with reproductive disorders and in 35% of the samples of clinically healthy sows. Species differentiation of the chlamydial antigen positive samples was done by southern blot hybridisation. Herewith C. psittaci could be diagnosed in all positive samples. Additionally 8 probes revealed a mixed infection with C. psittaci and C. trachomatis. The results of the present study show, that the prevalence of chlamydial infections in breeding herds is high and underline the importance of chlamydial infections for reproductive disorders. Single chlamydial infections as well as mixed infections with other pathogens must be considered.

Animals↗

PubMed2000

[Reproductive health in women in the Czech Republic 1993-1997. I. Study methodology and characteristics of the sample groups].

AIM OF THE STUDY: To identify changes in reproductive health status as a consequence of changes in the system of health care and social affairs. THE AIM OF THIS PART OF STUDY: To prepare the methodology of data collection and to identify changes of demographic characteristics. TYPE OF THE STUDY: Retrospective comparative epidemiological study. INSTITUTION: Institute for the Care of Mother and Child, Praha 4-Podolí. METHODS: Two nation-wide surveys on reproductive health of representative three-stage cluster samples in 1993 and 1997. After selection of residential sites from all districts the households were selected for interview. One hundred and fifty trained interviewers asked selected women of reproductive age (4,497 in 1993 and 1,735 in 1997) questions according to a special questionnaire. The basic demographic characteristics of the two samples were compared with the 1991 Census data. The 1993 Czech Republic Reproductive Health Survey was funded by the United States Agency for international Development via a WHO agreement; the 1997 Survey was funded by the Czech Statistical Office and Ministry of Health. RESULTS: The age structure is very similar in the 1993 sample and in the 1991 Census data, however, there is a remarkably lower proportion of women 15-19 years of age in the 1997 sample. According to the marital status, the 1997 sample has a higher proportion of women living in partner-strip and divorced women. The 1997 sample has a higher proportion of women with only one child and there were fewer women with 4 and more children. Also the proportion of women with secondary education with higher school certificate was higher in the later sample. CONCLUSION: This part of the study evaluate a changes in four demographic characteristics of women of reproductive age, because these changes could influence the reproductive health indicators (contraception, induced abortions), which are the subject of further analysis.

Adolescent↗

PubMedDate not supplied

Public or private providers? U.S. women's use of reproductive health services.

CONTEXT: U.S. women receive contraceptive and reproductive health services from a wide range of publicly funded and private providers. Information on trends in and on patterns of service use can help policymakers and program planners assess the adequacy of current services and plan for future improvements. METHODS: Women who reported in the 1995 National Survey of Family Growth that they had obtained any contraceptive or other reproductive health service in the past year were classified by their primary source of care, and the services they received, their characteristics and their primary source of care were analyzed. Logistic regression was used to test which factors predict women's use of publicly subsidized family planning clinics and of specific types of services. RESULTS: The percentage of women of reproductive age who obtained family planning services increased slightly between 1988 and 1995, primarily among women aged 30 and older. Nearly one in four women who received any contraceptive care visited a publicly funded family planning clinic, as did one in three who received contraceptive counseling or sexually transmitted disease (STD) testing and treatment. Women whose primary source of reproductive care was a publicly funded family planning clinic received a wider range of services than women who visited private providers; moreover, the former were significantly more likely to report obtaining contraceptive care or STD-related care, even after the effects of their background characteristics were controlled. Young, unmarried, minority, less-educated and poor women were more likely than others to depend on publicly subsidized family planning clinics. Source of health insurance was one of the most important predictors of the use of public family planning clinics: Medicaid recipients and uninsured women were 3-4 times as likely as women with private insurance to obtain clinic care. CONCLUSIONS: Publicly funded family planning clinics are an important source of contraceptive and other reproductive health care, providing millions of U.S. women with a wide range of services. Since women's need for reproductive care and for publicly subsidized care is not likely to diminish, clinics may be financially challenged in their efforts to continue delivering this broad package of services to growing numbers of uninsured or disenfranchised women.

Adolescent↗

PubMedDate not supplied

Reproductive parameters of male dromedary and bactrian camels.

Functional anatomy of male reproductive organs and reproductive physiology of dromedary and bactrian camels are quite similar except for some differences in the seasonal pattern of reproductive events: left testes bigger than right; scrotum not pendulous; vas deferens very convoluted with 2 mm diameter; prostate divided into 2 parts by septum, with many ducts; bulbourethral (Cowper's) glands well developed and seminal vesicle absent; fibroelastic penis has "prescrotal" sigmoid flexure and the glans resembles crochet needle; triangular-shaped prepuce directed posteriorly to open to the rear, and can move cranially or caudally during erection or urination, respectively; semen ejaculate, 1-12 mL in volume with little gelatinous material, coagulates and liquifies within minutes; total sperm/ejaculate 6 x 10(9) sperm/mL; semen contains PGE1, PGE(2x,LH), estradiol progesterone/other metabolites; semen collected by AV used for bulls with long copulation time; ovulation induced 36-48 h after mating or insemination; sperm of a short life of 1-6 h at 0.4 degrees C, is prolonged in presence of mucopolysaccharide gel; fresh semen inseminated. Topics of future research on endocrinology of reproduction, gonadal physiology, semen biology assisted reproductive technology, and gene transfer to germ cells of camels are outlined. The prevention and control of STD is an important component of camel stud management to improve reproductive performance in this species.

Animals↗

PubMedDate not supplied

Reproductive health services for adolescents under the State Children's Health Insurance Program.

CONTEXT: The federal government enacted the State Children's Health Insurance Program (CHIP) in 1997 to provide insurance coverage to uninsured, low-income children up to age 19. Individual states' decisions when designing their CHIP efforts will in large part determine the extent to which the program will help the nation's nearly three million low-income uninsured adolescents get needed reproductive health services. METHODS: CHIP administrators in all states and the District of Columbia were sent a survey concerning reproductive health services for adolescents aged 13-18 provided under their state's CHIP effort. The questionnaire asked about services covered, information provided to adolescents, confidentiality, outreach and enrollment activities, managed care and performance measures. RESULTS: Of the 46 respondents to the survey, 29 states and the District of Columbia included a Medicaid component to their CHIP effort, and 28 states included a state-designed component. Overall, states provided relatively comprehensive coverage of reproductive health services, with all 58 CHIP programs covering routine gynecologic care, screening for sexually transmitted diseases and pregnancy testing. Fifty-four covered the full range of the most commonly used prescription contraceptive methods, although only 43 covered emergency contraception. Twenty of 58 CHIP programs required that adolescents be provided with information about coverage for the full range of reproductive health services, and 18 required that information be provided about accessing care. Seventeen programs reported guarantees of confidentiality before and after receipt of reproductive health care. In 26 programs, enrollees in managed care were guaranteed access to contraceptive services through out-of-network providers. Twenty-six states and the District of Columbia reported targeting outreach activities specifically to adolescents, and 41 states and the District of Columbia stated that they provide outreach materials at middle schools, high schools and community-based organizations serving teenagers. CONCLUSIONS: Despite their nearly comprehensive coverage of reproductive health services, programs were inconsistent in guaranteeing the information, confidentiality and flexibility in choosing providers that is critical to adolescents' ability to access care. In addition, many states failed to creatively use strategies to target uninsured adolescents for enrollment, although new initiatives are under way to correct this problem.

Adolescent↗

PubMed2001

Reproductive ageing and the menopause.

This brief review describes early work initiated by Anne McLaren and John Biggers, in which they repeated on mice a very early experiment carried out by John Hunter on pigs, to test the effect of unilateral ovariectomy on subsequent breeding performance. This and subsequent experiments led to the conclusion that reproductive ageing in the female mouse was largely due to ageing changes in the uterus. As a result of these changes fewer implanted blastocysts are carried to term in the older females, with the result that the size of litters produced gradually drops and ceases altogether well before the expected time of death, thus leading to a period of reproductive inactivity at the end of life. Other organs undergo ageing changes but it appears to be those in the uterus which limit reproductive performance in the female. The somatic organs concerned in bringing the male gametes into the environment are still able to function effectively almost until the time of death so that males have a very short period of reproductive inactivity at the end of their lives. Due to the prenatal onset of meiosis in the germ cells, female mammals and some, but not all, other vertebrates are born with a finite crop of oocytes in the ovary, which cannot be increased after birth. Nevertheless, with the exception of women, female mammals appear to be able to produce ova well into old age, and have them fertilized. When examined after death the ovaries still contain oocytes so this is not a limiting factor in reproduction in old females. In women the situation is completely different. They also have an extended period of reproductive quiescence in middle and old age, the menopause, but, unlike other female mammals, this is not due to failure of the uterus but is caused by the ovary becoming depleted of oocytes in middle age. The reason women run out of oocytes before the end of life, whereas the other mammals which have been studied do not, is associated with the greatly extended lifespan of humans compared to other mammals of equivalent size. There is a linear relationship between longevity and body weight in mammals, small mammals have much shorter lives than large ones. This is probably associated with the increased production of free radical oxygen necessary to maintain body temperature in smaller animals. Heat is lost through the body surface which becomes relatively less as the animal increases in weight, so the smaller animal has to metabolise and thus produces more free radical oxygen to maintain body temperature. For reasons unknown this seems not to apply to humans. The menopause has thus evolved as a consequence of two adaptations: the prenatal onset of meiosis, common to all mammals and many other vertebrates and the greatly increased longevity of all humans, both male and female. In view of this dual origin it is unlikely to have evolved in response to an adaptive need to have grandmothers to help rear the young, as has been suggested!

Aging↗

PubMed1997

Plant reproduction in spaceflight environments.

Because plant reproduction is a complex developmental process there are many possible sites of perturbation by the unusual environments of orbital spacecraft. Previous long-duration experiments on Soviet platforms shared features of slowed development through the vegetative stage of plant growth and aborted reproductive function. Our goal has been to understand how special features of the spaceflight environment impact physiological function and reproductive development. In a series of short-duration experiments in the Shuttle mid-deck we studied early reproductive development in Arabidopsis thaliana. Pollen and ovule development aborted at an early stage in the first experiment on STS-54 which utilized closed plant growth chambers. Post-flight analysis suggested that the plants may have been carbon dioxide limited. Subsequent experiments utilized carbon dioxide enrichment (on STS-51) and cabin air flow-through with an air exchange system (on STS-68). Both modifications allowed pollen and ovule development to occur normally on orbit, and full reproductive development up to the stage of an immature seed occurred on STS-68. However, analysis of plant roots from these experiments demonstrated a limitation in rootzone aeration in the spaceflight material that was not mitigated by these procedures. In the future, additional resources (crew time, upgraded flight hardware, and special platforms) will invite more elaborate, long-duration experimentation. On the ISS, a variable speed centrifuge and upgraded plant habitats will permit detailed experiments on the role of gravity in shaping the plant micro-environment, and what influence this plays during reproduction.

Arabidopsis↗

PubMed2001

Possible effects of endocrine disruptors on male reproductive function.

Endocrine disruptors act to alter blood hormone levels or the subsequent action of hormones, including effects on hormone production, release, transport, metabolism and/or elimination together with effects on cognate receptor binding and/or subsequent intracellular receptor actions. Confirmed alterations in reproductive development in wildlife species together with reports touting an increase in the incidence of human male reproductive tract abnormalities and decreased adult sperm counts in some parts of the world have increased public concern with endocrine disruptors. A biological plausible hypothesis has suggested that man-made chemicals act as endocrine disruptors resulting in altered development of the reproductive tract causing the observed effects. Based on current knowledge, the impact of endocrine disruptors on the male reproductive function remains to be appreciated. Epidemiological human studies are necessary to fill in the gap in our knowledge. Disturbances of hormonal regulation during fetal or postnatal development in humans may induce adverse effects on the male reproductive system, but these adverse effects of endocrine disruptors on humans are subtle, and difficult to research and detect. We have investigated fetal exposure to endocrine disruptors in Japan by analyzing umbilical cords, and changes of testis-weight in Japanese men by using analytical data of necropsy. This mini-review summarizes current endocrine disruptor issues on possible effects of endocrine disruptors on male reproductive function and the results of our recent research.

Cryptorchidism↗

PubMed2002

A temperate reef fish, Tautogolabrus adspersus, (Walbaum) as a potential model species for laboratory studies evaluating reproductive effects of chemical exposure.

In ecotoxicological testing, there are few studies that report on reproductive output (egg production) of marine or estuarine fish. Cunner (Tautogolabrus adspersus) were studied as a potential model species to evaluate the impact of pollutants with estrogenic activity on reproduction in estuarine fish populations. Cunner inhabit marine and estuarine areas where contaminant discharges are likely. Baseline values for cunner gonadosomatic index (GSI), hepatosomatic index (HSI), and plasma vitellogenin (VTG) were determined in a field reference site (April 1999-December 1999). Male and female GSI indicated that cunner spawning is synchronized. Female HSI and VTG increased prior to GSI. From our laboratory observations, cunner are suitable for conducting experiments with reproductive endpoints indicative of both exposure (vitellogenin levels) and effects (egg production). However, cunner are not sexually dimorphic and stripping ripe fish is the only method to distinguish sex. In preparation for laboratory exposure studies with cunner, we designed a laboratory experimental holding system to accommodate cunner's reproductive behavior, a vertical spawning run to the water surface. Cunner were successfully acclimated from overwintering torpor to spawning condition in the laboratory by gradually changing the environmental conditions of fish held at winter conditions (4 degrees C and 9:15-h light:dark photoperiod) to spawning condition (18 degrees C and 15:9-h light:dark photoperiod). Our results show that cunner successfully spawned daily in the laboratory. They produced fertile eggs in our experimental system designed to accommodate cunner's vertical spawning runs, demonstrating that male and female reproductive behavior was synchronized in the laboratory. Our observations indicate that cunner would be a useful model species for evaluating reproductive effects of environmental contaminants in laboratory studies.

Animals↗

PubMed2002

[Ovarian tumors in the reproductive age group].

OBJECTIVES: Analysis of the type and localization of the ovarian tumors in the reproductive age group of women. MATERIALS AND METHODS: The study group consisted of all women operated on Gynecologic Surgery Department of Polish Mothers's Memorial Hospital-Research Institute due to ovarian tumors in 1996-99. As the reproductive age we defined 18-39 year, when the majority of deliveries occurs. RESULTS: We analyzed 326 patients operated on the ovarian tumors. In 60 cases (18.4%) we noticed ovarian malignant tumors, in 7 (2.1%) borderline tumors and in 259 (79.5%) benign cysts. In the reproductive age (130 women) the incidence of ovarian malignancies was significantly lower (4.6%), higher for benign tumors (93.1%) and constant for borderline malignancy (2.3%), p < 0.005. The most common malignancy among all patients was epithelial cancer--83.4% (germ cell and metastatic--8.3%, both), but in the reproductive age group (6 cases) germ cell tumors were the majority--66.8% (epithelial and metastatic--16.6%, both), p < 0.005. In women aged 18-39 yr. with ovarian malignancies 4 of them had I stage of the disease and 2 were in the stage III. 121 women in the reproductive age were operated on the benign ovarian tumors; 107 (88.4%) had unilateral cysts and 14 (11.6%) had tumors in both ovaries. On histology we revealed 31.1% of endometrioid cysts, 28.9%--teratomas, 19.3%--serous, 3.7%--mucinous and others (hemorrhagic, functional, sex cord, inflammatory) in the remaining 17%. CONCLUSION: In the reproductive age ovarian tumors are mainly unilateral benign cysts. Only a few of ovarian tumors were malignant but the majority of them were in the early stage of the disease.

Adult↗

PubMed1994

[An analysis of Korean women's reproductivity].

An analysis of reproductivity is mainly concerned with the measurement of net force of fertility expressed in terms of a generation rather than in a given year. The present study examined current trends of Korean Women's reproductivity interpreting general reproduction and net reproduction rates, intrinsic rate of natural increase and mean length of gestation. The data used for this analysis were drawn from the national fertility surveys from 1970 through 1990 conducted by the Korea Institute for Population and Health. The figures of the present study revealed that the reproduction rates of Korea during the last 20 years decreased from 2.22 in 1970 to 0.71 in 1990 and net reproduction rates also dropped from 1.9 to 0.69 during the same period of time. Furthermore, from this study, it is noticed that the replacement level of fertility had been reached since the early 1980s. The intrinsic rate of natural increase as measure of population growth under existing conditions of fertility and mortality and free of the influence of the current age distribution, is computed. The level of rate was not much changed and was 0.3 in 1970 compared with 0.25 in 1990, which is still higher than other developed countries. The mean age of mother at the birth of their daughters defined as the length of generation has been slightly changed from 23.9 in 1971 to 25.8 in 1990.

Age Factors↗

PubMed2002

(Re)defining reproductive health with and for the community: an example of participatory research from Mali.

Qualitative research was carried out in central Mali to inform the development of curricula for an intervention to improve young people's reproductive health. Both the young people and 'societal gatekeepers' (including religious leaders and traditional healers) perceived reproductive health to comprise the social dynamics in which reproductive health decision-making is embedded and not just the biological aspects of sexual relations and fertility. Their definitions of reproductive health reflected social taboos about pre-marital sex, infidelity and illegitimate children, and comprised holistic notions of bodily and spiritual cleanliness. It is argued that the 'Cairo' definition sees many of the social factors identified by respondents as comprising the context or background of reproductive health. The findings presented here indicate that local populations may see them as integral to the concept itself. It is discussed how the 'Cairo' definition of reproductive health needs to be made culturally specific in order to facilitate programme design and implementation.

Adolescent↗

PubMed2003

Comparing data on the reproduction of Varroa destructor.

Varroa destructor reproductive success is considered an important character for determining the resistance of honey bees to this mite parasite. However, most of the published data are not comparable due to the different methods of ascertaining and reporting reproduction. A recently published technique that involves reconstructing mite families in older worker brood gives repeatable and reliable parameters. This methodology was used to compare various categories of reproduction of approximately 1,000 V. destructor females in each of three studies on Africanized bees in Brazil and Mexico and European bees in England. The most objective and useful measure was the determination of the number of viable females per female that had invaded the worker brood in singly infested cells, which was denominated the "effective reproduction rate". Viable females are those that can reach the adult stage and have a mate available. The effective reproduction rate in worker brood was 0.64, 0.73 and 1.01 in Brazil, Mexico and England, respectively. Standardization of reproduction determination techniques would make published data comparable and much more useful.

Animals↗

PubMed2003

[The haematogenous reproduction theory of Aristotle].

From the very beginning, man has been fascinated by the continuous coming into being of new life on Earth. Archeological and anthropological data indicate that in prehistoric times, reproduction was attributed to a fertility goddess that required no sperm for this purpose. In the early historical Middle East it was believed that a godly being brought about pregnancy by using male and female semen. It was the merit of the Greek philosophers of the 6th-3rd century B.C. to realize that reproduction was governed by natural laws. Several theories were developed to understand how reproduction could occur. The haematogenous theory of reproduction, developed by Aristotle, has received the most attention. The essence of this theory is that the male sperm, with a haematogenous origin, causes the development of an embryo from menstrual blood present in the female uterus. The theory survived about 2000 years, with modifications, and was also introduced into Christianity. It was only about 150 years ago that the reproduction theory based on hypotheses was changed into a reproduction science based on facts.

Famous Persons↗

PubMed1992

Epidemiology of occupational reproductive hazards: methodological aspects.

Both male and female workers may be exposed to occupational agents which affect their reproductive processes. Reproductive outcomes are important in their own right, for example teratogenic effects and impaired neurological development. In addition, reproductive impairment may indicate germ cell mutation, which has far-reaching implications. Research into reproductive effects is beset with pitfalls. Applying the results of toxicological research may be suggestive, but such extrapolation is very unreliable owing to profound differences in reproductive and/or toxicological mechanisms. Epidemiological data are therefore indispensable. Optimal methods of data collection and study design, comparable with similar studies of other populations, are essential. Otherwise reliable conclusions cannot be drawn, and this is a waste of resources and of the work and cooperation of everyone who participates in the research. In considering study design, the key question is the measurement (or minimally, the accurate description) of exposures, which is more problematic than the ascertainment of reproductive outcome variables. From the viewpoint of exposures, case control studies have the same disadvantage as studies of the general population, that exposures are heterogeneous, and most specific exposures are therefore rare, even in a large study; in addition, measurement is particularly difficult in this situation. Occupationally defined populations have the corresponding advantages of relative homogeneity and availability of data, although even here numerous problems exist, which are well known. Outcomes can be assessed by means of biological or questionnaire-based methods. They are best regarded as complementary, as each has its strengths and weaknesses.(ABSTRACT TRUNCATED AT 250 WORDS)

Abnormalities, Drug-Induced↗

PubMed2005

[Survey on reproductive health status of Shanghai college students].

OBJECTIVE: To explore reproductive health condition of college students in Shanghai and provide scientific basis for reproductive health education. METHODS: From July 2004 to March 2005, 1192 college students (majors including medicine, science and engineering, arts and culture; 618 medical students and 549 non-medical; 555 male and 612 female) from seven time-day colleges in Shanghai were investigated with a reproductive health questionnaire involving sex. The questionnaire was constituted by 72 topics, involving the need of education, sex attitude, sex videos, sex hygiene knowledge and sexually transmitted diseases (STDs), etc. RESULTS: 39.33% (459/1167) students thought they had accepted formal sex education; 49.19% (574/1167) students chose lecture as the favorite way; 41.90% (489/1167) students thought the reproductive health education would not increase the incidence of premarital sexual behavior; 64.10% (748/1167) students thought it was necessary to give college students reproductive health instructions and knowledge. On the other hand, we found 45.05% (250/555) boys and 27.45% (168/612) girls could accept the premarital sexual behaviors; 35.32% (196/555) boys and 39.38% (241/612) girls could accept premarital pregnancy; 44.39% (518/1167) students could calculate the safe period accurately; 71.38% (833/1167) students knew emergency contraception measures; 57.67% (673/1167) students knew how to and when to use condoms; To our surprise, only 2.19% (12/549) non-medical students and 12.14% (75/618) medical students knew exactly the whole 4 sexually transmitted diseases that needed to be essentially prevented in China. CONCLUSION: At present, the reproductive health condition of college students in Shanghai is sophisticated. Much more education on sex safety, self-protection skills and acquired immunodeficiency syndrome (AIDS) knowledge, etc should be reinforced.

Acquired Immunodeficiency Syndrome↗

PubMed2004

The regulation of science and the Charter of Rights: would a ban on non-reproductive human cloning unjustifiably violate freedom of expression?

Non-Reproductive Human Cloning (NRHC) allows researchers to develop and clone cells, including non-reproductive cells, and to research the etiology and transmission of disease. The ability to clone specific stem cells may also allow researchers to clone cells with genetic defects and analyze those cells with more precisions. Despite those potential benefits, Parliament has banned such cloning due to a myriad of social and ethical concerns. In May 2002, the Canadian Government introduced Bill C-13 on assisted human reproductive technologies. Bill C-13 deals with both the scientific and the clinical use of human reproductive materials, and it prohibits a number of other activities, including NRHC. Although the Supreme Court of Canada has never ruled on whether scientific experiments area form of expression, academic support exists for this notion. The authors go through the legal analysis that would be required to find that scientific experiments are expression, focusing in part on whether NRHC could be considered violent and thus fall outside the protection of section 2(b). The latter question is complicated by the ongoing policy debate over whether an "embryonic cell" is property of human life. The authors then consider whether a ban on NRHC could be justified under section 1 of the Charter. They conclude that both the breadth of the legislative purpose and the proportionality of the measure are problematic. Proportionality is a specific concern because the ban could be viewed as an outright denial of scientific freedom of expression. Although consistent with current jurisprudence on freedom of expression, this paper runs against the flow of government policy in the areas of regulation and prohibition of non-reproductive human cloning. As there has been no Charter litigation to date on whether scientific research is a form of expression, the authors introduce a new way of looking at the legality of the regulation of new reproductive technologies.

Biomedical Research↗

PubMed2006

[A list and analysis of reproductive medicine periodicals indexed in MEDLINE in 2006].

MEDLINE established by National Library of Medicine (NLM), USA, is the most commonly used biomedical literature retrieval system, whose indexed literature generally represents the top of the medical world. Of the total number of 4959 journals listed in the Lists of Journals Indexed in MEDLINE (2006) published by NLM, 46 are periodicals of reproductive medicine, mainly including andrology, fertility, and sterility. Researchers of reproductive medicine should be familiar with the journals indexed in MEDLINE, closely follow their published frontier researches in this field, and consciously contribute to them in English. Editors of reproductive medicine journals should endeavour to have their journals included in such internationally authoritative systems as MEDLINE, SCI, etc by publishing them in English in compliance with international standards. This article presents a list of the reproductive medicine periodicals indexed in MEDLINE (2006) together with a brief analysis, which is meant to help researchers in reproductive medicine, andrology and other relevant fields with their contribution, subscription, reading and retrieving, as well as to share some more knowledge about MEDLINE and its indexed journals with Chinese editors of reproductive medicine journals.

Bibliometrics↗