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Effect of level of dietary calcium-phosphorus during growth and gestation on calcium-phosphorus balance and reproductive performance of first-litter sows.

Twenty-four bred gilts were used in a Ca-P metabolism trial. Twelve gilts were fed gestation treatment A (13 g Ca, 10 g/day), while the other 12 were fed gestation treatment B (19.5 g Ca. 15 g P/day). One-half of the gilts in each treatment group were fed .65% Ca, .50% P from 7 to 94 kg, and half were fed .975% Ca, .75% P for the same period. Treatment B gilts excreted more (P less than .005) fecal and urinary P. Twenty-four first litter sows fed the same treatment diets during growth and gestation and given .75% Ca, .50% P during lactation were used in a Ca and P balance trial conducted from day 38 to 42 of lactation. No difference in fecal, urinary or milk Ca or P were noted between sows fed the different diets during growth or gestation. A higher (P less than .05) value for Ca balance during lactation was observed for sows fed treatment diet B during gestation than for those fed gestation diet A. There were growth treatment x gestation treatment interactions (P less than .05) for both Ca and P balance. No differences were noted in total pigs farrowed, total pigs farrowed alive, average weaning weight or number of pigs weaned. Birth weights were higher (P less than .05) for pigs from sows fed diet B during gestation than for pigs from sows fed diet. A. Pre- and postfarrowing weights, weaned sow weight and lactation gain were similar regardless of treatment fed during growth or gestation.

Animal Feed↗

Reproductive performance in crosses of Angus, Santa Gertrudis and Gelbvieh beef cattle.

Angus (A), Santa Gertrudis (S), and Gelbvieh (G) sires were mated to A and S dams to produce five mating types (A X A, S X S, S X A, A X S and G X A) in each of four calf crops. The study involved 501 matings. Overall means for the traits measured (calves born/cows exposed, Julian birthdate, calving ease, percentage of live calves at 24 h, birth weight, survival to weaning and gestation length) were 74.2%, 48.8 d, 96.4%, 33.2 kg, 95.4% and 283.8 d, respectively. Angus dams had a 14 percentage point (P less than .05) advantage over S dams for percentage of calves born/cows exposed. The effect of heterosis in crosses of A and S for percentage of calves born/cows exposed was negative (-11.1%) and approached significance. The percentage of calves born/cows exposed were 84.4, 70.4, 76.1 and 62.3 for the A X A, S X S, S X A and A X S mating types, respectively. Matings involving A sires and dams produced calves significantly earlier in the calving season than did matings involving S sires and dams. Matings involving S sires and dams produced calves with significantly longer gestation periods than matings of A sires and dams. Calving ease score and survival to weaning were not affected by breed of sire, breed of dam, age of dam, sex of calf, or the interaction of breed of sire X breed of dam. Percentage of live calves at 24 h indicated that straightbred S calves were significantly less viable at birth than the other four mating types.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Observations on ploidy of cells and on reproductive performance in parthenogenetic turkeys.

Using flow cytometry, the ploidy levels of parthenogenetic turkeys were quantified from blastodisc stage to adulthood. Eggs were collected from noninseminated hens of the Beltsville Small White flock, known for their high degree of parthenogenesis, and the blastodermal cells from developing embryos were compared with those of embryos produced by hens inseminated with semen from males of the same flock. Erythrocytes of parthenogens from Day 10 of incubation to 27 mo of age were also used for ploidy determination. Sperm and erythrocyte preparations from normal males of the above flock served as haploid and diploid standards, respectively. In parthenogenetically developing blastoderms, 40.3 +/- 14.5% of the cells were haploid and 48.9 +/- 11.9% diploid; blastoderms from fertilized eggs had no haploid cells. The haploid cell content of parthenogens declined from the blastodermal stage to adult life, with 1.9 +/- 2.3% at 10 to 20 d of embryonic development, 1.5 +/- 1.4% at 21 to 29 d of development, 1.4 +/- 2.6% at 4 wk posthatch, and 1.3 +/- 1.9% in adulthood, although changes between the 1st mo after hatch and adult stage were not significant. It is possible, therefore, that parthenogenetic embryos with a low proportion of haploid cells could be the ones that survive to Day 10 of development and beyond, whereas those with a higher proportion of haploid cells fail to develop. The semen volume of male parthenogens was significantly lower than that of normal males, although the concentration of spermatozoa and their fertilizing capacity did not vary significantly between groups, suggesting that the germ cells of these parthenogens are capable of normal meiosis and sperm maturation leading to a normal fertility.

Animals↗

Influence of imposed feed intake patterns during lactation on reproductive performance and on circulating levels of glucose, insulin, and luteinizing hormone in primiparous sows.

Thirty-six primiparous sows were assigned to one of five treatments designed to mimic the lactation feed intake patterns observed in a previous study of commercial farms: high energy intake (HHH) or low energy intake during each week of a 3-wk lactation (LLL), or reduced intake during wk 1 (LHH), wk 2 (HLH) or wk 3 of lactation (HHL). The metabolizable energy intake of sows was either 16.5 (H) or 6.5 (L) Mcal/d. Diets were equal in lysine, providing 45 g/d. The HHH sows had a shorter (P < .05) weaning-to-estrus interval (9 +/- 3.2 d) than the sows in the LLL (23 +/- 3.5 d), HLH (22 +/- 3.5 d), and HHL (18 +/- 3.2 d) groups. The LH pulse frequencies of HHH (d 14: 1.5 pulses/8 h; d 21: 2.1 pulses/8 h) were greater (P < .05) than those of LLL (.2 pulses/8 h) and HLH (.5 pulses/8 h) on d 14 and those of LLL (0 pulses/8 h) and HHL (.9 pulses/8 h) on d 21 of lactation. No differences (P > .1) in mean serum concentrations of LH were observed among treatment groups either on d 21 of lactation or on d 1 postweaning. When fed a low-energy diet, sows had lower (P < .05) concentrations of serum insulin and plasma glucose than did sows fed a high-energy diet. Our results indicate that energy intake during lactation influences circulating insulin and glucose levels and LH pulse frequency and amplitude during midlactation and during the postweaning period.

Animal Feed↗

Fixed effects in the formation of a composite line of beef cattle: I. Experimental design and reproductive performance.

Red Angus (RA) dams were mated to Charolais (C) or Tarentaise (T) sires to produce crossbred (F1) progeny. Members of the F1 generation, differing in breed direct effects, were mated to produce an F2 generation with an expected breed composition of 1/2 RA, 1/4 C, and 1/4 T. Two breed groups within the F2 generation differing in breed maternal effect ([C x RA] x [T x RA] and [T x RA] x [C x RA]) were identified separately. These breed groups were crossed to produce an F3 generation and, likewise, the two resulting F3 generation breed groups were crossed to produce an F4 generation. No distinction was made among breed groups subsequent to the F3 generation. Pregnancy rates averaged 90.9% over 11 yr, with 82.0% of cows exposed weaning a calf. Among formative generations of this composite population, F2 had greatest pregnancy, calving, and weaning rates. Age of dam significantly affected pregnancy rate, calving difficulty, and gestation length. Older cows tended to express higher pregnancy rates and longer gestation lengths than did younger cows (P < .01). Males calves had a 1.7% greater weaning rate than female calves (P < .05), but matings producing male calves had longer gestation lengths (P < .05) and were 8.5% more likely to experience calving difficulty (P < .01). Individual breed additive effects (calves from C or T sires mated to RA dams) were important for calving difficulty only (P < .05), where C-sired matings experienced greater calving difficulty. Differences between C x RA and T x RA dams, indicative of maternal breed additive effects, were not detected.(ABSTRACT TRUNCATED AT 250 WORDS)

Analysis of Variance↗

Effects of T-2 toxin on reproductive performance and health of laying hens.

Purified T-2 toxin was fed to S.C.W.L. hens at levels of 0 (control), 0.5, 1.0, 2.0, 4.0 and 8.0 p.p.m. of an otherwise balanced diet. Feed consumption, egg production and shell thickness were significantly (P less than 0.05) decreased in hens fed 8 p.p.m. as compared with control hens. The fertility and progeny performance were not depressed by feeding T-2 toxin, but the hatchability of fertile eggs of hens fed 2 and 8 p.p.m. was significantly (P less than 0.05) lower than that of hens fed the control diet. The weights of liver, heart, gizzard and spleen were not influenced by T-2 toxin. Serum levels of alkaline phosphatase, LDH and uric acid of hens fed high concentrations of T-2 toxin were greater than those of control hens. SGPT in hens fed 8.0 p.p.m. was lower when compared with control hens. No outward changes in hematocrit, hemoglobin, erythrocyte, leukocyte and differential leukocyte counts were noted with feeding T-2 toxin. Most hens fed T-2 toxin developed oral lesions: circumscribed proliferative yellow caseous plaques at the margin of the beak, mucosa of the hard palate and angle of the mouth, and tongue. The incidence and severity of lesions were proportional to the dietary level of T-2 toxin. The only other lesion observed in necropsy examination at the end of the experiment was the small mucosal ulcer in the anterior portion of the gizzard in hens fed high levels of T-2 toxin. Microscostrointestinal tract, etc.) revealed no significant pathological change except the necrotic lesions in the gizzard and crop.

Alanine Transaminase↗

Improvement of reproductive performance in crossbred zebu anestrous primiparous cows by treatment with norgestomet implants or 96 h calf removal.

The aim of the present study was to compare the effect of norgestomet implants (NI) and calf removal (CR) for 96 h on estrus induction and first service fertility in crossbred zebu primiparous anestrous cows after 120 days postpartum. A total of 152 cows in a tropical environment were allotted to three experimental groups: CR for 96 h (n = 51), NI for 9 days plus 500 IU of PMSG at implant removal (n = 51) and a control group (CG) without treatment (n = 50). Estrous rate (%) and mean interval to first estrus (days) were 50.9 and 26.3+/-6.8; 60.7 and 13.8+/-6.8; 16.0% and 61.8+/-5.9 days for groups CR, NI and CG, respectively. CR and NI were statistically similar, however, both groups were different (P < 0.01) when compared with CG. Calving interval to first service and to conception were: CR: 151.2+/-8.4 and 157.8+/-21.4; NI: 145.2+/-8.5 and 150.9+/-21.3; CG: 186.8+/-7.3 and 201.0+/-18.5. A difference (P < 0.01) was found in both intervals when comparing the CR and NI with CG, with longer intervals for cows in the CG group. First service conception rates were 61.5, 67.7 and 62.5% for groups CR, NI and CG, respectively, and were not different (P > 0.05). These results demonstrate the efficacy of NI + PMSG or temporary CR for 96 h in inducing a fertile estrus and shortening the interval to estrus and to conception in primiparous crossbred anestrous zebu cows in the tropics.

Anestrus↗

Digestibility of fiber components and reproductive performance of sows fed high levels of alfalfa meal.

Two experiments were conducted with second-parity sows fed either 5 or 50% alfalfa meal diets (Exp. 1) or 5, 50 or 95% alfalfa meal diets (Exp. 2) beginning 30 d after breeding and continuing through lactation, 21 d postpartum. Diets in both experiments were calculated to be equal in crude protein, but different in metabolizable energy content. Feed intake was restricted to 2 kg/d during gestation and ad libitum during lactation. Sows were tethered in metabolism crates 45 d after breeding. Total feces were collected during two 5-d collection periods, 60 and 100 d after breeding. Digestibilities of dry matter, fiber components (neutral detergent fiber, acid detergent fiber, hemicellulose and cellulose), protein and energy were determined in both experiments for all diets and periods of gestation. In both experiments, there was a reduction (P less than .05) in digestibility of dry matter, fiber components, protein and energy with increasing fiber levels for both periods of gestation. In Exp. 1, the decrease in digestibility of dry matter, neutral detergent fiber, acid detergent fiber, cellulose and energy was greater at 100 d gestation than at 60 d in sows fed 50% alfalfa. In Exp. 2, 50 and 95% dietary alfalfa reduced 60-d digestibilities of dry matter, all fiber constituents, energy and protein; these digestibilities were further reduced (P less than .05) at 100 d of gestation. In Exp. 1, weight gains of sows fed 5 and 50% alfalfa diets from breeding to 109 d gestation, were 42 and 18 kg/sow (5 greater than 50% level, P less than .05).(ABSTRACT TRUNCATED AT 250 WORDS)

Animal Feed↗

Influence of lactation length and feed intake on reproductive performance and blood concentrations of glucose, insulin and luteinizing hormone in primiparous sows.

Twenty-four pregnant gilts were assigned to four experimental treatments in a 2 x 2 factorial arrangement. The first factor was lactation length (12 vs. 21 days) (LL); the second factor was a provided amount of diet (FF, full feeding vs. low, 2 kg/day). The same diet (1% lysine and 3.27 Mcal ME/kg) was used from farrowing to 1 day after weaning. Sow body weight, backfat thickness (BF), litter weights, and blood samples were measured prior to and 1 day after weaning. Sows were monitored for estrous once daily in the presence of a boar until 35 days after weaning or until estrous was detected. Average feed intake during lactation (ADFI) was 1.9 (low) and 4.0 (FF) kg/day. ADFI among individual sows varied from 1.8 to 4.9 kg/day. Positive effects of both LL and feed intake treatments were found (P < 0.05) on sow body weight loss, backfat loss, glucose concentrations, mean luteinizing hormone (LH) concentrations, and LH pulse frequency prior to weaning, and farrowing-to-estrous interval. Greater concentrations of insulin prior to weaning were associated only with feed intake treatment (P < 0.05). No interactions between LL and feed intake treatments were found in any measures except for sow body weight loss. Using regression analysis, greater lactation feed intake was associated with greater concentrations of insulin and glucose, greater LH pulse frequency prior to weaning and shorter farrowing-to-estrous interval in both LL treatments. We suggest that greater feed intake during lactation improves farrowing-to-estrous interval through LH release regardless of LL treatment.

Animals↗

Reproductive performance of two generations of female semidomesticated mink fed diets containing organic mercury contaminated freshwater fish.

Semidomesticated female mink (Mustela vison) were fed daily diets containing 0.1 ppm, 0.5 ppm, and 1.0 ppm of total mercury. Piscivorous and nonpiscivorous fish naturally contaminated with organic mercury were used to prepare the diets. Twenty-month-old females (G1 generation) that were exposed to the experimental diets for approximately 400 days in 1994 and 1995 and their 10-month-old female offspring (G2 generation) that were exposed to mercury for approximately 300 days in 1995, were all mated to 10-month-old males. Males were fed the diet containing 0.1 ppm mercury 60 days prior to the mating season. Diets containing 0.1 ppm and 0.5 ppm were not lethal to G1 and G2 females for an exposure period of up to 704 days. At the age of 11 months, mortalities occurred in 1994 for G1 females (30/50) and in 1995 for G2 females (6/7) fed the 1.0 ppm mercury diet after 90 days and 330 days of exposure, respectively. The length of the gestation periods and the number of kits born per female were not different among dietary groups for the two generations of females. The proportion of females giving birth was low for all groups, except for the G1 females fed the 0.1 ppm diet. There was an inverse relationship between whelping proportion and exposure group, but was not statistically significant. There was evidence that kits were exposed to mercury both in utero and/or during lactation as indicated by the presence of mercury in their livers. Mercury exposure did not influence the survival and growth of neonatal kits.

Animals↗

Effect of altering dose of PG600 on reproductive performance responses in prepubertal gilts and weaned sows.

This study evaluated the effects of altering dose of PG600 on estrus and ovulation responses in prepubertal gilts and weaned sows. Experiment 1 tested the effects of one (1.0x, 400IU eCG+200IU hCG, n=74), one and a half (1.5x, n=82), or two (2.0x, n=71) doses of PG600 for prepubertal gilts. Estrus (58%) and ovulation (90%) were not affected (P>0.10) by dose. Higher doses increased (P<0.01) numbers of corpora lutea (17, 24, and 25), but not (P>0.10) the proportion of gilts with cysts (26, 36, and 46% for 1.0x, 1.5x, and 2.0x, respectively). Experiment 2 tested the effects of 0x (n=30), 0.5x (n=32), 1.0x (n=29), or 1.5x (n=30) doses of PG600 in weaned sows. Dose did not influence return to estrus (90%, P>0.10). There was an effect of dose (P<0.05) on incidence of cysts (3.4, 1.8, 6.4, and 29.8%, for 0x, 0.5x, 1.0x, and 1.5x doses, respectively). The 0.5x dose increased (P<0.01) farrowing rate (83.2%) compared to 0x (72.1%) and 1.5x (58.6%), but was not different from 1.0x (76.4%). Total pigs born (10.5+/-0.8) did not differ (P>0.10) among treatments. These data suggest that increasing dose of PG600 to 1.5x for gilts increases the number of corpora lutea but does not alter the proportion expressing estrus or ovulating. Reducing dose of PG600 for weaned sows did not alter estrus or ovulation, but the 0.5x dose increased farrowing rate compared to no PG600.

Animals↗

Reproductive performance of sows treated with a combination of pregnant mare's serum gonadotropin and human chorionic gonadotropin at weaning in the summer.

During the summer and fall of 1987, sows from eight herds in three states were assigned randomly to receive either a combination of 400 IU of pregnant mare's serum gonadotropin with 200 IU of hCG (P.G. 600) or no treatment at weaning. A treatment x parity interaction was observed for days to first estrus after treatment and percentage anestrus (percentage of sows not achieving estrus within 10 d after weaning). Relative to primiparous control sows, primiparous sows given P.G. 600 expressed estrus sooner (P less than .02) after weaning (6.0 vs 7.8 +/- .6 d) and exhibited less (P less than .02) postweaning anestrus (15.6 vs 29.2 +/- 4.0%). Second parity sows that received P.G. 600 showed estrus sooner (P less than .06) than second-parity control sows (4.7 vs 6.4 +/- .7 d). Days to first estrus after treatment did not differ between groups for parity-three and older sows, and percentage anestrus was not different between treatments for parity-two and older sows. The herd X treatment interaction was significant for percentage recycled (percentage of successfully mated sows that returned to estrus), subsequent farrowing rate, and subsequent number of pigs born dead. Number of pigs born alive was lower for sows treated with P.G. 600 than for control sows (10.55 vs 10.10 +/- .18; P less than .02). In summary, treatment of sows weaned in the summer and fall with P.G. 600 had decreased days to postweaning estrus in parity-one and -two sows and reduced frequency of postweaning anestrus in primiparous sows.

Anestrus↗

Urogenital diseases and their effect on reproductive performance in high-parity sows.

UNLABELLED: In a Slowakian indoor pig production unit (2423 sows), from June to December 2002 all culled sows with excessive vulval discharge at culling, and with vulval discharge and periparturient disease in their previous history were subjected to retrospective lifetime production analysis. The sows were assigned to nine groups according to parity (parity 1-9). Average total litter size, average live-born litter size, average stillbirth rate, average mummy rate, and average litter weaning weight were evaluated retrospectively for all births. Non-culled sows represented the control animals. The percentage of animals with periparturient disease and vulval discharge in their history differed between parities. Parity 2, 3, and 4 sows had a significantly lower percentage of vulval discharge and periparturient disease in their history than sows of other parities. Compared to parity 1-6 sows, parity 7-9 sows had significantly lower (P < .001) conception rates, farrowing rates, and adjusted farrowing rates. Compared to parity 1-2 and 7-9 sows, parity 3-6 sows had a significantly larger (P < .001) lifetime average total born and live-born litter size. Compared to parity 1-3 and 7-9 sows, parity 4-6 sows had a significantly lower (P < .001) rate of stillbirths over all parities. No differences in mummy rates were detected between the sows of different parities. Compared to parity 1-2 and 7-9 sows, parity 3-6 sows had significantly higher (P < .001) weaning litter weights over all parities. Sows without a history of vulval discharge and periparturient disease had higher (P < .001) production levels in parity 7-9. IMPLICATIONS: The present results indicate that parity markedly influences the production level of sows that have a history of periparturient disease and vulval discharge.

Animals↗

Evaluation of reproductive performance in lactating dairy cows with prostaglandin F2alpha, gonadotropin-releasing hormone, and timed artificial insemination.

Nine hundred and twenty Holstein cows from 16 commercial dairy herds to evaluate three systematic breeding protocols: 14-d PGF2alpha, timed artificial insemination (AI), and GnRH-PGF2alpha, relative to AI following estrus detection without hormone intervention. The timed AI protocol involved GnRH, followed by PGF2alpha 7 d later and GnRH again 2 d after PGF2alpha, with AI 6 to 18 h after the second GnRH. The GnRH-PGF2alpha protocol consisted of GnRH followed by PGF2alpha 7 d later. Eight herds relied on visual observation to detect estrus, and eight herds utilized the HeatWatch estrus detection system. The average interval to first postpartum AI was shortest for the timed AI protocol (77.1 d) followed by the 14-d PGF2alpha protocol (81.6 d). There was no difference in days to first AI between the control (86.1 d) and GnRH-PGF2alpha (89.5 d) protocols. Percent pregnant per first AI did not differ among control (45.6%), 14-d PGF2alpha (43.7%), or GnRH-PGF2alpha (44.0%) protocols, but all protocols had a higher percent pregnant per first AI than the timed AI protocol (30.1%). Response to the GnRH-PGF2alpha protocol was limited because 44.0% of the cows submitted to the protocol were not detected in estrus < or = 10 d post-PGF2, administration and had an interval to first AI of 103.8 d. Cumulative percent pregnant by 120 d postpartum did not differ between control cows (53.1%) and hormonally treated cows (50.6%). Visual observation herds had a shorter interval to first postpartum AI (82.8 d) than the HeatWatch herds (84.8 d), with a higher overall rate of estrus detection across all protocols (75.3 and 67.6%, respectively).

Animals↗

The influence of early age mastectomy and unilateral ovariectomy on reproductive performance of the bovine.

The effects of mastectomy and unilateral ovariectomy and their interaction during the postpartum period were examined in 26 Angus heifers. At birth, the animals were assigned to a 2 x 2 factorial arrangement of treatments: mastectomy and unilateral ovariectomy, mastectomy, unilateral ovariectomy and unoperated suckled control. Surgeries were performed at approximately 2 months of age, and animals were observed through three consecutive postpartum intervals (PP1, PP2, and PP3). There were no significant influences of mastectomy or ovariectomy on age at puberty, age at first conception or services required for first conception. Mastectomy reduced the number of days from parturition to ovulation (PP1, 32.1 vs 52.5, P less than .01; PP2, 21.6 vs 59.9, P less than .01; PP3, 20.6 vs 46.7, P less than .01) The interval from parturition to first estrus was shorter for heifers in the mastectomized group (PP1, 45.3 vs 76.2, P less than .05; PP2, 28.7 vs 69.9, P less than .01; PP3, 32.4 vs 62.3, P less than .05) as was the interval from parturition to conception during PP2 (60.0 vs 104.9, P less than .05). The interval between calvings was shorter for heifers in the mastectomized group than for controls, but the difference was significant only between the second and third parturitions: 338.5 vs 399.2 (P less than .01). Mastectomy reduced the standard deviation for the interval between parturition 2 and parturition 3 (55.9 vs 15.9; P less than .01), the interval between parturition and return to estrus in PP2 (56.3 vs 11.4; P less than .01) and the interval from calving to conception PP1 (92.2 vs 31.4; P less than .01). Unilateral ovariectomy did not have a significant influence on any of the postpartum intervals, nor were there any significant interactions.

Age Factors↗

The effects of nutrition on the reproductive performance of Finn x Dorset ewes. II. Post-partum ovarian activity, conception and the plasma concentration of progesterone and LH.

After lambing forty-five ewes were allocated to three groups, two of sixteen and one of thirteen ewes. The lambs of the two groups of sixteen ewes were weaned on Day 1 after lambing and the ewes were fed a diet of 100% (Group H) or 50% (Group R) of maintenance energy requirements. The thirteen ewes in the third group (Group L) suckled twin lambs and were fed freely. During the first 3 weeks after lambing, oestrus was observed for 11/16 (Group H) and 8/16 (Group R) ewes; of the ewes which had shown oestrus in the two groups, ovulation occurred in 5/8 and 5/7 respectively. Only 1/13 Group-L ewes showed oestrus and ovulated during the same period. The mean plasma concentrations of progesterone and LH were unaffected by the treatments and were around 0-4 and 1-5 ng/ml, respectively. Restricted feeding had no effect on oestrus, ovulation or the hormone levels during the oestrus cycle following synchronization. The onset of oestrus and the start of the preovulatory discharge of LH were 3 and 6 hr later, respectively, in the lactating ewes (Group L) than in those in Groups H and R. Ewes in Group L also had a higher ovulation rate, 2-8 +/- 0-2 versus 2-1 +/- 0-2 (P less than 0-05). Restricted feeding reduced the number of ewes lambing; only 1/11 ewes in Group R, considered to have conceived because of the presence of high progesterone levels 17 days after mating, subsequently lambed compared with 6/12 in Group H and 5/9 in Group L.

Animal Nutritional Physiological Phenomena↗

Effects of deslorelin or hCG administration on reproductive performance in first postpartum estrus mares.

A tendency for deslorelin implants to suppress subsequent follicular growth and delay return to estrus following induced ovulation has been documented in nonlactating mares. To investigate this phenomenon in lactating mares, 22 broodmares in southeast Texas were administered either deslorelin or hCG to induce ovulation in the first postpartum estrus during February and March 2001. Mares were teased daily and examined twice weekly (Tuesdays and Thursdays) by transrectal ultrasonography. When a follicle >35 mm diameter was detected on Tuesday, mares were treated with either 2,500 U hCG administered intravenously or with one implant (2.1 mg) deslorelin administered subcutaneously. Mares were bred every other day until ovulation was detected or until they ceased behavioral estrus, and were examined 16 days after treatment to detect pregnancy. Follicular measurements were recorded for all mares during each examination, and interestrous intervals were recorded for mares not becoming pregnant. Treatment of mares with either hCG or deslorelin resulted in similar ovulatory responses and pregnancy rates. Deslorelin-treated mares had fewer ovarian follicles >20 mm in diameter 16 days after treatment than hCG-treated mares (P < 0.01). Interestrous intervals for mares failing to become pregnant on foal heat breeding were prolonged in deslorelin-treated compared to hCG-treated mares (P < 0.01). Date of treatment was negatively correlated with length of the interestrous interval in deslorelin-treated mares (P < 0.01), but was not correlated with length of interestrous interval in hCG-treated mares (P > 0.10). All mares failing to become pregnant from foal heat breedings became pregnant from later breedings, but the parturition to conception interval was prolonged in deslorelin-treated compared to hCG-treated mares that did not become pregnant on foal heat (P < 0.01).

Animals↗

Reproductive performance, pain recurrence and disease relapse after conservative surgical treatment for endometriosis: the predictive value of the current classification system.

BACKGROUND: To assess the predictive value of the current classification of endometriosis in terms of response to surgical treatment, we studied to what extent disease stage, lesion type and lesion site were associated with post-operative pregnancy rate, symptom recurrence and disease relapse. METHODS: A total of 729 women with endometriosis undergoing first-line conservative laparoscopic surgery were included. Data on age at surgery, disease stage according to the revised American Fertility Society (AFS) classification, anatomical characteristics of endometriotic lesions, fertility status and types and severity of pain symptoms were collected. RESULTS: Minimal endometriosis was present in 222 patients, mild in 106, moderate in 197 and severe in 204. The cumulative probability of pregnancy at 3 years from surgery in 537 infertile women was 47% (51% at stage I, 45% at stage II, 46% at stage III and 44% at stage IV; log-rank test, chi(2)3=1.50, P=0.68). The cumulative probability of moderate or severe dysmenorrhoea recurrence in 425 symptomatic subjects was 24% (32% at stage I, 24% at stage II, 21% at stage III and 19% at stage IV; log-rank test, chi2(3)=6.39, P=0.094). The cumulative probability of disease relapse was 12% (3% at stage I, 11% at stage II, 11% at stage III and 23% at stage IV; log-rank test, chi(2)3=24.95, P=0.0001). Using Cox's multivariate proportional hazards regression analysis, no association was observed between endometriosis stage or lesion type and lesion site and any of the considered study outcomes. CONCLUSIONS: The current classification of endometriosis has an inadequate predictive value with regard to the major clinical outcomes.

Adult↗