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At least 1,063 records · Page 59Linked to original sources
PubMed1989

A transmission electron microscope study of fibroblast changes in human deciduous tooth pulp.

The coronal pulps of four primary canines, free from radicular resorption, and of three primary teeth, with roots entirely resorbed, were prepared for electron microscopy. Mature fibroblasts, similar to those reported in the pulps of permanent teeth, were present in the pulps of the clinically mature teeth. Regression of fibroblasts, evident in the pulps of deciduous teeth at the root resorption stage, was characterized by cytoplasmic changes, modifications in the cytoskeleton and dissociation of cells and fibrils. Deciduous teeth might provide a model for studying pulp fibroblast ageing.

Actin Cytoskeleton↗
PubMed1985

Studies of a family manifesting premature exfoliation of deciduous teeth.

We report observations made on a family in which the children manifested premature exfoliation of the deciduous incisors and canines beginning as early as 1.5 years of age. We observed gingival recession, alveolar bone resorption, tooth loosening and exfoliation without apical root resorption in the absence of clinical signs of inflammation. The children's mother, age 26, had a normal periodontium, but the father, age 30, had periodontitis of moderate severity. Exfoliated deciduous teeth from one of the children were examined histologically and features characteristic for hypophosphatasia were seen. However, localized prepubertal periodontitis could not be ruled out from these data alone. The differential diagnoses for this type of condition are discussed.

Adult↗
PubMed2001

[Periodontal disease and calcitonin].

A biological action of calcitonin (CT) is to inhibit osteoclastic resorption, and has the action which promotes recovery of a periodontal resorption. Although there are few studies on the effect of CT on periodontal disease, the relation between osteoporosis and periodontal disease is being to be clarified, and since osteoclasts cause resorption of the alveolar bone and the root resorption, it is considered there is a possibility of treatment of periodontal disease by CT.

English Abstract↗
PubMed1989

[Retrograde root filling utilizing resin and a dentin bonding agent: indication and applications].

With Gluma a methacrylate-based resin may be chemically bonded to dentin with considerable strength. Resin may therefore be used for retrograde root fillings. Whereas a retrograde amalgam filling demands a box-like preparation, retroplast (Gluma and resin) may be applied to a slightly concave root surface. It may therefore be employed in areas normally inaccessible with amalgam technique. Retroplast can thus be used on roots of all molars and to restore root perforations, root resorptions, cracks, grooves and defects of the root. In addition on lateral canals, on extremely thin roots and to cover perforating root canal posts, this technique can also be used. Dentin/root-cement transplantation may be performed for the purpose of reattachment. The article discusses the technique and its applications with examples showing that it may result in satisfactory healing.

Composite Resins↗
PubMed1992

An investigation of replantation of traumatically avulsed permanent incisor teeth.

The success of treatment of 46 replanted, avulsed permanent incisors in 36 children was investigated in relation to some of the factors which have been reported to affect prognosis. Treatment was considered to have been successful if the tooth was still present in the mouth and required no further treatment. If more treatment was necessary, the outcome was considered to be uncertain, while if the tooth had been lost a failure was recorded. Treatment was considered to be successful for 21 teeth, uncertain for 20 teeth and a failure for 5 teeth. A significant relationship was found between success and the method of storing the avulsed tooth, with milk, saliva or saline being the best media. No relationship was demonstrated between the time the avulsed tooth was out of the mouth and success. Root resorption was the most frequent complication of replantation and occurred in 24 teeth. However, no significant relationship between resorption and the time that the avulsed tooth was out of the mouth was demonstrated.

Adolescent↗
PubMedDate not supplied

[Orthodontic treatment and periodontal problems. 1].

Because of the increasing frequency of orthodontic treatments of patients with periodontal problems, the authors evaluate effects deriving from orthodontic treatment on periodontal tissues and provide practical indications to manage such patients. Experimental and clinical studies on effects of trauma from occlusion on periodontal tissues in different clinical conditions are examined. The authors have also considered studies dealing with periodontal response to different orthodontic therapy items, with particular regard to gingival inflammation degree and likelihood of root resorption. From the results of such clinical and experimental studies, the authors have pointed out clinical indications to treat periodontal patients.

Animals↗
PubMed1993

A ten-year evaluation of the quality of orthodontic treatment.

A 10-year evaluation of the quality of orthodontic treatment at the Department of Orthodontics, School of Dentistry in Malmö, University of Lund, showed that in approximately 3 cases out of 4 (73%) successful results were noted in the malocclusions under treatment. In approximately half the cases the ideal treatment goal, normal occlusion, was achieved. The treatment was unsuccessful in 12% and in a large group of patients (15%) the treatment was discontinued due to lack of motivation or compliance. More accurate study and documentation of subjective need of treatment (motivation, cooperation and social sufficiency) would improve the quality of orthodontic care and make it more efficient. Some sort of penalty due to distinct lack of patient cooperation might improve orthodontic care. Root resorption occurred frequently during orthodontic treatment with multiband fixed appliances, but the apical shortening was small and without clinical significance.

Adolescent↗
PubMed1990

The case for postoperative orthodontics in orthognathic surgery.

In patients with orthognathic problems, in whom a combination of surgery and orthodontics is required, it seems to us better to defer orthodontic treatment until after surgery has been completed and a possible relapse tendency has petered out. This conclusion is reached on the basis of arch instability and the incidence of root resorption as reported in the orthodontic literature. The soundness of "permanent retention" after orthodontic therapy is questioned. The author's concepts are illustrated with a few case reports.

Humans↗
PubMed2004

Effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of periodontal attachment following tooth replantation in dogs.

OBJECTIVES: Subcutaneous and intramuscular implants of bone morphogenetic protein-12 (BMP-12) have been shown to induce formation of tendon and ligament tissue. BMP-12 induced a new attachment with a distinct fibrocartilaginous zone at the tendon-bone interface in the rat tendon-bone attachment model. Surgical controls showed poor healing and failure to reform the appropriate tendon-bone attachment morphologically. Application of recombinant human BMP-12 (rhBMP-12) to periodontal defects suggests that rhBMP-12 has the potential to support regeneration of the periodontal ligament (PDL). The objective of this pilot study was to evaluate this effect of rhBMP-12 in a tooth replantation model. METHODS: Six, young adult, male Hound Labrador mongrel dogs were used. Maxillary and/or mandibular incisor and premolar teeth were extracted and the PDL was either left "intact" or removed by root planing. rhBMP-12 (1.0 mg/ml) or a buffer control was topically applied to teeth with "intact" PDL in contralateral jaw quadrants in each of 3 animals. The teeth were immersed in 1.0 ml of the rhBMP-12 or the buffer solution for 10 min and then replanted. The remaining three animals received rhBMP-12 (1.0 mg/ml) and the buffer control in a similar fashion applied to teeth instrumented to remove the PDL and cementum, and surface demineralized with citric acid. The animals were euthanized at 8 weeks postsurgery and block sections were collected and processed for histopathologic analysis. RESULTS: No dramatic differences were found between teeth receiving topical rhBMP-12 and the buffer control. Application of rhBMP-12 did not have an apparent effect on new cementum and PDL formation in the tooth replantation model. Moreover, application of rhBMP-12 did not increase nor did it decrease the apparent presence and extent of ankylosis along the root surface compared to the control. CONCLUSIONS: The observations from this study do not support the use of topical rhBMP-12 to support the reestablishment of the PDL including regeneration of cementum and functionally oriented fibers, and to prevent ankylosis and root resorption following replantation of teeth.

Animals↗
PubMed1990

Replacing resorbed maxillary central incisors with mandibular premolars.

A case report is presented on autotransplantation of a lower premolar into the upper central incisor area. A traumatized upper central incisor lost because of external root resorption was replaced by a premolar transplant taken from a crowded mandibular arch. The transplant showed excellent adaptation and the periapical inflammation noticed a few years after the operation was treated successfully with apicectomy.

Bicuspid↗
PubMedDate not supplied

[Splinting technique for traumatic luxation of anterior permanent teeth].

Extrusive luxations of both, upper and lower incisors, represent a frequent event in dental traumatology. The Authors present some cases in which elastic splints have been used. In fact recent researches show that, even soon after a traumatic event, is not indicated to immobilize teeth with rigid fixed splints because they don't allow any dental function. It is therefore preferable the use of elastic splints for 2-4 weeks, instead of rigid splints for long periods. The Authors then describe the techniques, the methods and the radiographic controls and pulp tests used in this kind of traumatic pathology, showing the positive long term results obtained by using elastic splints instead of rigid splints which often present as result root resorptions or pulp necrosis. In fact with elastic splints is possible to replace and maintain luxated teeth, allowing at the same time a certain function of teeth and their support tissues.

Dental Pulp Necrosis↗
PubMed2006

Clinical evidence and literature to compare two different therapeutic protocols in tooth avulsion.

AIM: This is to assess the priority in tooth avulsion: replantation as quickly as possible and deferred endodontic treatment, or replantation and elimination of every irritating stimulus for the periodontal ligament. The objective is to establish a univocal protocol by analysing and comparing the various components of these therapeutic procedures. MATERIALS AND METHODS STUDY DESIGN: 20 patients were selected and divided into 2 groups: in group A we focused our attention on the rapidity of replantation, in group B we focused on the elimination of the necrotic pulp and every possible irritating stimulus that might lead to root resorption of inflammatory nature. RESULTS: Clinically, dental mobility seems to be greater in the first group. However after 15 days teeth have a comparable mobility and after one month they all show a mobility degree 1. Radiographically a greater incidence of resorption can be observed in group A compared to group B as in the first one a higher number of replanted teeth undergo resorption. Such lesions have the tendency to remain constant or even increase. CONCLUSIONS: The results of this study seem to take only one direction: extraoral endodontic therapy.

Clinical Protocols↗
PubMed2005

Soluble cytokine receptor treatment in experimental orthodontic tooth movement in the rat.

Pro-inflammatory cytokines, such as interleukin-1 (IL-1) and tumour necrosis factor-alpha (TNF-alpha), are believed to play a role in the biological processes involved in the course of orthodontic tooth movement and especially in root resorption. The inhibition of cytokine activity, e.g. by soluble receptors, could be beneficial in reducing this unwanted side-effect. The aim of this study was to investigate the role of cytokines IL-1 and TNF-alpha in the course of experimentally induced tooth movement. The upper left first molar was moved orthodontically in 80 male Wistar rats using a coil spring with a force of 0.5 N. Starting at day -1, three groups of 20 animals each received daily intraperitoneal injections (ip) of 2 ml of 1 mug/ml soluble receptors (a) to IL-1(sIL-RII), (b) to TNF-alpha (sTNF-alpha-RI) and (c) a combination of (a) and (b). Twenty animals served as the control. After 3, 6, 9 and 12 days, the animals were killed in groups of five. The amount of tooth movement was registered and the maxillae were prepared for histological and histomorphometric analysis. Osteoclasts and odontoclasts were identified using tartrate-resistant acid phosphatase (TRAP) histochemistry. The amount of tooth movement was reduced in all receptor-treated groups by approximately 50 per cent. At the same time, the number of TRAP-positive cells on the desmodontal bone surface and on the surface of the roots was reduced. Thus, systemic application of soluble receptors to IL-1 and TNF-alpha following experimental induction of tooth movement in the rat reduced the number of osteoclasts as well as odontoclasts.

Acid Phosphatase↗
PubMed2004

[New treatment protocols for avulsed teeth].

Traumatized teeth present a clinical challenge with regard to their diagnosis, treatment plan and prognosis. The injuries to the permanent dentition include crown and root fractures, subluxations, luxations and tooth avulsion. Common complications are pulp necrosis, periapical pathosis and root resorption. This article will describe new clinical modalities for the treatment of avulsed teeth and discuss the rational for their use.

Demeclocycline↗
PubMed1994

Ridge augmentation following extraction of replanted central incisor.

Regeneration of bone defects remains a clinically important problem in many instances. This paper reports on the use of membrane technique combined with decalcified freeze-dried bone allograft to promote bone formation after extraction of a replanted central incisor with extensive root resorption. The procedure prevented ridge reduction, both buccolingually and apicocoronally, and will facilitate prosthetic replacement of the lost tooth without esthetic problems.

Adolescent↗
PubMed1976

Histological study on the postnatal development and sequence of eruption of the mandibular cheek-teeth of rabbits (Oryctolagus cuniculus).

The postnatal development and sequence of eruption of mandibular cheek teeth of rabbits were studied by histological methods. Hemi-mandibles were dissected and sectioned in longitudinal sections of 7 mu and stained with hematoxylin-eosin and Masson's trichrome. The presence of two mandibular deciduous molars which are replaced by corresponding premolars and of three mandibular permanent monofisary molars was confirmed. Eruption of deciduous molars of the mandible begins at 4 days after birth and of the mandibular permanent molars at 9 days, while that of mandibular premolars occurs at 23 days, replacing the mandibular deciduous molars which have exfoliated. At 32 days all the mandibular permanent cheek-teeth are erupted. At birth the mandibular deciduous molars are completely developed and at 4 days their root resorption is initiated. At the first day P3 is in the bell stage and the P4 has begun dentinogenesis. In M1 and M2 amelogenesis is observed.

Amelogenesis↗