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Results for “SOCIAL ISOLATION”

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PubMed1995

The glycine/NMDA receptor antagonist, L-701,324 reverses isolation-induced deficits in prepulse inhibition in the rat.

Previous studies have demonstrated that the glycine/NMDA receptor antagonist, L-701,324 (7-chloro-4-hydroxy-3(3-phenoxy)phenyl-2(H)quinolone) blocks the activation of mesolimbic dopamine systems induced following psychostimulant administration in the rat (Bristow et al. 1994). In the present study, pretreatment with L-701,324 also reversed the deficit in prepulse inhibition (PPI) observed in rats reared in social isolation after weaning. Given that PPI is also attenuated in schizophrenic patients and that isolation rearing induces both neurochemical and behavioural abnormalities suggestive of a physiologically induced state of dopaminergic hyperactivity, these results suggest that blockade of the glycine/NMDA receptor may offer a new strategy for the development of novel antipsychotic agents.

Acoustic Stimulation↗

PubMed1995

Seasonal variation of depressive symptoms in Antarctica.

Symptom characteristics and risk factors for seasonal variation in depressive symptoms were prospectively examined in 119 men and women who overwintered in Antarctica. Over a 12-month period, this cohort reported significant increases in their global depressive symptom scores as well as several individual symptoms associated with winter depression. Summer depression and marital status were significant independent predictors of winter depression. Factor analyses of summer and winter symptoms revealed a set of symptoms traditionally associated with the winter-over experience in a distinct factor not found in summer. These results indicate that even asymptomatic, clinically normal populations experience seasonal variation in mood in high-latitude environments. However, this seasonal variation may be the result of social isolation during the winter months rather than the prolonged absence of sunlight.

Adult↗

PubMed1992

If A-B does not predict heart disease, why bother with it? A clinician's view.

Ray asks the question: 'If A-B does not predict heart disease, why bother with it?' (British Journal of Medical Psychology, 64 (1) 1991). Having worked for several years in prevention of heart attack recurrence, I am inclined to agree with his conclusion that the construct is a trail which should now be abandoned. Grief, hostility and social isolation, fear and work demands have each been implicated in heart disease independently of Type A.

Bereavement↗

PubMed1989

A case-comparison analysis of elder abuse and neglect.

This study examines factors which contribute to elderly abuse and neglect by caregivers in a domestic setting. Methodological and conceptual variations and problems in previous studies have led to considerable confusion as to the determinants of this important social problem. A more rigorous research design was used in this study than has been previously employed. Fifty-nine abused elders from a model project site for the study of elderly abuse were compared with forty-nine non-abused clients from a home care program in the same agency. Using a research instrument designed by the authors, data related to the following aspects of the lives of the elders and their caregivers were collected: psychological status, stressful life events, social networks, mutual dependency, and the nature of their relationships. The study indicates that members of abusive families are more likely to have emotional problems which contribute to interpersonal difficulties. Abused elders are not more dependent on caregivers for many of their daily needs. However, the abused elderly and their caregivers have become increasingly interdependent prior to the onset of abuse because of the loss of other family members, increased social isolation, and the increased financial dependency of the perpetrator on the elderly person.

Aged↗

PubMed2000

Regulation of energy intake in older adults: recent findings and implications.

Inadequate energy intake is common in older individuals and is probably the major cause of unexplained weight loss. This summary highlights recent studies on possible causes of negative energy balance in older individuals suggesting that aging is associated with a significant impairment in the regulation of food intake that inhibits appropriate short-term and long-term compensation for normal fluctuations in energy intake. The combination of a reduced ability to regulate energy intake, decreased dietary variety, and disadvantageous social factors such as functional limitations, social isolation and depression, increases the risk of negative energy balance leading to weight loss in older individuals.

Aged↗

PubMed1999

Interviewing vulnerable old people: ethical and methodological implications of imagining our subjects.

It is sometimes argued that interview research with vulnerable social groups, such as frail, lonely, older people, has distinctive ethical and methodological requirements. The conventional one-off, professional interview is seen to be both inadequate as a method of data collection and inimical to the interest of research subjects. While ideologically persuasive, such a view is not derived from systematic analysis of actual interviews. In this article, I describe a research project on social isolation in which the conceptualization of elderly interviewees as "vulnerable subjects" had a number of critical but intended impacts on the course and outcomes of the research. I offer an empirically grounded analysis of the interview situation that suggests an alternative reading of the relationship between social representation of aging persons and the methods we use to study them.

Aged↗

PubMed1990

Ecology of depression in late childhood and early adolescence: a profile of daily states and activities.

This study investigated daily states and time use patterns associated with depression. Four hundred eighty-three 5th to 9th graders reported on their experience when signalled by pagers at random times. Depressed youth reported more negative affect and social emotions, lower psychological investment, lower energy, and greater variability in affect. These differences were weaker for 5th and 6th graders, suggesting that self-reported feeling states are a poor indicator of depression prior to adolescence. No differences were found in the daily activities of depressed youths nor in the amount of time spent alone, but depressed youths experienced other people as less friendly and more often reported wanting to be alone, especially when with their families. They also spent less time in public places and more time in their bedrooms. Finally, depressed boys, but not girls, spent much less time with friends, particularly of the same sex, suggesting that social isolation is more strongly associated with depression for boys.

Adolescent↗

PubMed2002

Living with a pressure ulcer: a descriptive study of patients' experiences.

This qualitative study explored the perceptions and feelings of patients with pressure ulcers. Five participants who had suffered from pressure ulcers extending into the subcutaneous tissue and deep fascia were interviewed. A semi-structured interview technique was used, in which participants were asked a series of open questions based on the reviewed literature and the author's clinical experience. Content analysis was used to analyse the interview transcripts. The following themes emerged: pain, exudate levels, loss of independence, emotional factors, worry about healing, relationships, body image and social isolation.

Activities of Daily Living↗

PubMed2004

Socialization experiences and coping strategies of adults raised using spoken language.

This investigation concerned the socialization experiences and coping strategies of a group of 28 deaf adults who were raised using spoken language. Most respondents reported some level of social isolation because of (1) limitations in communication with hearing peers; (2) missing information in social, academic, and work settings; and (3) a sense of being "different." Most participants also reported strategies used to reduce isolation and mitigate the social difficulties associated with their hearing loss.

Adaptation, Psychological↗

PubMed2004

Ethological analysis of a polar team in the French Antarctic station Dumont d'Urville as simulation of space teams for future interplanetary missions.

This new ethological study focuses on the co-adaptation of the crew's spatial behavior to social isolation in a polar base thus simulating long-term living and working of a space team. The method consisted in drawing the subjects' position (n=13) on an observation map at the midday and evening meals at the Dumont d'Urville French station in Antarctica, daily during the summer campaigns and weekly during the winter-over of the TA46 mission. Quantitative data are presented in geocentric (positions), allocentric (distances) and egocentric (orientations) analyses with an emphasis on three adaptative periods (first 3 months, intermediary 2 months and last 3 months of isolation). Results show a large space occupancy during the first week after arrival and the last week before departure from the polar base, and a team-members' grouping during the winter-over. On the over-all time, the inter-individual distances increase. The social orientations are higher at the beginning than at the end of the mission. Discussion underlies the pertinent use of such ethological indicators collected from polar stations as predictors of well-being and optimal-working of the future orbital and planetary stations users.

Adaptation, Psychological↗

PubMed1998

Social network characteristics as mediators in the relationship between sexual abuse and HIV risk.

Recent research suggests that sexual abuse may be a potent risk factor for engaging in HIV risk behaviors for women. This relationship is likely mediated by the long term sequelae of sexual abuse. One plausible causal pathway posits that specific social network characteristics increase HIV risk exposure opportunities. This is premised on the belief that previous sexual abuse predisposes some women to become members of risk networks characterized by deviant behaviors and that HIV risk occurs in the context of these networks. One hundred and thirty women opiate users were systematically recruited from methadone maintenance and syringe exchange programs in New York City. The women participated in a one hour interview and provided information on drug use and frequency, HIV drug and sex risk behaviors, social network characteristics, and sexual abuse histories. Univariate and logistic regression techniques were used to test the relationship between sexual abuse and increased HIV risk as mediated by social network characteristics. Previous sexual abuse was strongly related to all social network characteristics examined. Moreover, these network characteristics appeared to affect patterns of drug use in identifiable ways. Social isolation was the only network characteristic associated with both HIV drug and sex risk behaviors. However, although a history of sexual abuse was significantly associated with five of the seven specific HIV risk behaviors examined, the relationship between sexual abuse and HIV risk behaviors remained unchanged when social network characteristics were included in the statistical model. Overall, the results suggest that a sexual abuse experience or its aftermath influence behavior far into the future. However, the results of this study did not show social network characteristics mediating the relationship between sexual abuse and HIV risk. Rather, previous sexual abuse and social network characteristics appear to be independent contributors to HIV risk behaviors for women.

Adult↗

PubMedDate not supplied

Psychosis and destitution at Christmas 1985-88.

Surveys of the destitute were conducted over four successive Christmas periods in Central London, UK. Functional psychosis with hallucinations and/or delusions, either current (19%) or in the past (22%), were associated with extreme social isolation and imprisonment.

Bias↗

PubMed1998

Conditioned release of 5-hydroxytryptamine in vivo in the nucleus accumbens following isolation-rearing in the rat.

This study examined the effect of isolation-rearing in the Lister hooded rat on extracellular 5-hydroxytryptamine in the medial nucleus accumbens following footshock and in relation to a conditioned emotional response. Inescapable mild footshock was associated with an immediate and prolonged increase in extracellular 5-hydroxytryptamine in the medial nucleus accumbens of isolation-reared rats. In group-reared rats (footshock-treated) and control groups (no footshock) there was no significant change in extracellular 5-hydroxytryptamine levels. When exposed to the contextual stimulus 140 min later (testing box without shock) there was an immediate and long-lasting increase in extracellular 5-hydroxytryptamine in the nucleus accumbens of the isolation-reared rats, however, the contextual stimulus did not significantly affect extracellular 5-hydroxytryptamine in the medial nucleus accumbens of group-reared rats. The results show that exposure to footshock and conditioning to context are not normally associated with a change in extracellular 5-hydroxytryptamine in the medial nucleus accumbens, however, in rats exposed to social isolation from weaning, both stimuli increase extracellular 5-hydroxytryptamine. The isolation-induced increase in presynaptic serotonergic function in the medial nucleus accumbens contrasts with previous reports of reduced 5-hydroxytryptamine release in the hippocampus and therefore suggests that isolation-rearing differentially affects the function of serotonergic neurons in the brain. The changes in 5-hydroxytryptamine function in the medial nucleus accumbens may represent physiological adaptations to stress or may occur secondary to changes in the function of another neurotransmitter, possibly dopamine.

Animals↗

PubMed2000

Psychotic disorders in urban areas: an overview of the Study on Low Prevalence Disorders.

OBJECTIVE: This paper reports on a study designed within the framework of the National Survey of Mental Health and Wellbeing to: estimate the prevalence of psychoses in urban areas of Australia; identify profiles of symptomatology, impairments and disabilities; collect information on services received and needed; and explore quality of life issues in a broadly representative sample of people with psychotic illnesses. METHOD: The study was conducted over four areas in the Australian Capital Territory, Queensland, Victoria and Western Australia, as a two-phase survey: (i) a census and screening for psychosis of all individuals who made contacts with mental health services during a period of 1 month in 1997; and (ii) interviews with a stratified random sample (n=980) of the screen-positive individuals (n=3800) using a standardised instrument. RESULTS: The point prevalence (1 month) of psychotic disorders in the urban population aged 18-64 is in the range of 4-7 per 1000 with a weighted mean of 4.7 per 1000. People with psychotic disorders experience high rates of functional impairments and disability, decreased quality of life, persistent symptoms, substance-use comorbidity and frequent side effects of medication. Although the utilisation of hospital-based and community mental health services, as well as of public and non-governmental helping agencies, is high, the majority live in extreme social isolation and adverse socioeconomic circumstances. Among the many unmet needs, the limited availability of community-based rehabilitation, supported accommodation and employment opportunities is particularly prominent. CONCLUSIONS: The so-called 'low-prevalence' psychotic disorders represent a major and complex public health problem, associated with heavy personal and social costs. There is a need for a broad programmatic approach, involving various sectors of the community, to tackle the multiple dimensions of clinical disorder, personal functioning and socioeconomic environment that influence the course and outcome of psychosis and ultimately determine the effectiveness of service-based intervention.

Activities of Daily Living↗

PubMed1985

The effect of age on two kinds of aggressive behavior in inbred strains of mice.

Shock-induced aggressive behavior is absent or very weak in C57BL/6 mice at the age of 12 weeks, increases at the age of 16 weeks and reaches the highest levels at the age of 20 weeks. This age-dependent increase of aggressive responses is absent in BALB/c and DBA/2 mice at the three ages examined in our experiments. Social isolation induces a clear age-dependent increase of aggressive behavior in BALB/c and DBA/2 mice (the highest level being evident at 20 weeks of age) but not in C57BL/6 mice which are characterized by the lowest or absence of aggressive responses. These results are discussed in terms of the role of developmental and genetic factors in the expression of shock- and isolation-induced aggressive behavior in the laboratory mouse.

Age Factors↗

PubMed1994

A checklist for assessing risk of violent behavior in historically nonviolent persons.

Assessment of risk for violent behavior is of interest to clinicians and laymen alike. This article includes a discussion of issues related to assessment of risk of violent behavior. A review of the literature is provided. Using this information, the author suggests several factors that might increase the probability of violent behavior in historically nonviolent individuals, including antisocial behavior, social isolation, poverty, absence of support systems, severe situational stress, and substance abuse. A checklist for assessing risk of violent behavior is suggested.

Adaptation, Psychological↗

PubMed2000

A novel social situation and loneliness.

Although social isolation has been shown to have a negative long-term influence on feelings of loneliness, there has been no systematic investigation of situational influences on loneliness. The purpose of this study was to compare scores on the UCLA Loneliness Scale, the loneliness which people feel prior to performing a novel task, with those on the same scale after engaging in the task. 31 college freshmen were divided into those working alone (n = 14) and those working in a group (n = 17). Those who performed the novel task within a group felt significantly less lonely after than prior to performing the task and reported less loneliness than the students who performed the same task in isolation. An important implication of this study is that group interaction may directly and immediately reduce the amount of loneliness individuals feel.

Adolescent↗

PubMed1995

Perception and social consequences of tuberculosis: a focus group study of tuberculosis patients in Sialkot, Pakistan.

Treatment defaulting is one of the major causes of the failure of TB control programs. In Bethania Hospital, Sialkot, defaulting rates are high: 72% for the standard 12 months course and 56% for the 8 months course. Attrition is especially important in the first weeks of treatment: < 70% of the patients start the 10th week of treatment. A focus group discussion study has been carried out to gain a better understanding of the impact of social stigmatization, treatment cost and pregnancy on defaulting. The study population consisted of 3 male and 3 female groups each with 8 hospitalized TB patients. The study shows that TB is perceived as a very dangerous, infectious and incurable disease. This perception has many social consequences: stigmatization and social isolation of TB patients and their families: diminished marriage prospects for young TB patients, and even for their family members: TB in one of the partners may lead to divorce. Due to fear patients often deny the diagnosis and reject the treatment. While both male and female TB patients face many social and economical problems, female patients are more affected. Divorce and broken engagements seem to occur more often in female patients. Females are usually economically dependent on their husbands and family in law, and need their cooperation to avail of treatment. The belief that pregnancy enhances the risk for relapse decreases their marriage prospects. Pregnancy is also a reason for stopping TB treatment as both are considered as incompatible. The findings of this study reveal the urgent need for a health education campaign to convince the general population that tuberculosis is curable. All health care providers should act as destigmatizers.

Adolescent↗