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Results for “Angina Pectoris, Variant”

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PubMed1976

Ventricular reciprocal rhythm occurring in succession in a patient with a variant angina pectoris.

A clinical surface electrocardiogram (ECG) in which ventricular reciprocal rhythm occurred occasionally three times and probably seven times in succession together with paroxysmal ventricular tachycardia and ventricular extrasystoles in competition with sinus rhythm causing incomplete A-V dissociation is described. An ECG tracing of ventricular reciprocal rhythm occurring in succession has never been reported previously as far as can be ascertained from published reports.

Angina Pectoris↗
PubMed1986

Provocation of coronary spasm by dopamine in patients with active variant angina pectoris.

The effects of dopamine on arteries are different depending on the dose, route of administration, and receptor population. Its administration can cause vasodilation by stimulation of dopaminergic receptors, vasoconstriction by stimulation of alpha-adrenergic and serotonergic receptors, and even spasm of cerebral arteries when given intracisternally in dogs. The ability of dopamine to provoke coronary spasm was assessed in 18 patients with active vasospastic angina in whom this amine was infused at rates of 5, 10, and 15 micrograms/kg/min for periods of 5 min each. The 12-lead electrocardiogram and blood pressure (cuff) were monitored throughout the whole test. In nine patients dopamine caused angina and ischemic electrocardiographic changes suggestive of coronary spasm: ST segment elevation in six patients and ST segment depression in the absence of important coronary stenoses in the remaining three. Infusion of dopamine was repeated during coronary angiography in three patients with positive test results: this provoked occlusive coronary spasm with ST segment elevation in two patients and nonocclusive spasm with ST segment depression in the remainder. In conclusion, infusion of dopamine provokes coronary spasm in a sizeable proportion of patients with active vasospastic angina. Its administration may be detrimental in patients susceptible to coronary spasm, such as those with acute myocardial infarction.

Adult↗