The effects of physiological noise on the auditory threshold.
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OBJECTIVES: Cochlear implants (CI) are now widely used in patients with profound sensorineural deafness. Determining threshold levels for each CI electrode is required during the initial postoperative tuning session. While behavioral testing is appropriate in post-lingually deafened patients, it may be really tricky in pre-lingually deafened children. CI stimulation is responsible for auditory perception and logically induces brainstem reticular formation arousal which can be studied by sympathetic skin response (SSR). METHODS: Thirteen patients (aged 3-70 years) implanted with an MXM Digisonic((R)) were postoperatively studied. SSR as well as behavioral thresholds were recorded after electrical stimulation of CI electrodes at various intensities. RESULTS: SSR could be recorded in all patients including the 6 studied children. There was a strong correlation between SSR threshold and subjective auditory threshold (r=0.93). CONCLUSIONS: The present data indicate that SSR could have a clinical application as a routine test in postoperative fitting procedures of CIs especially in pre-lingually deafened children.
Western Atlantic sciaenids comprise a taxonomically diverse teleost family with significant variations in the relationship between the swim bladder and the otic capsule. In this study, the auditory brainstem response (ABR) was used to test the hypothesis that fishes with different peripheral auditory structures (black drum, Pogonias chromis and Atlantic croaker, Micropogonias undulatus) show differences in frequency selectivity. In a black drum the swim bladder is relatively distant from the otic capsule while the swim bladder in Atlantic croaker possesses anteriorly-directed diverticulas that terminate relatively near the otic capsule. Signals were pure tones in the frequency range, 100 Hz to 1.5 kHz, and thresholds were determined both with and without the presence of simultaneous white noise at two intensity levels (124 dB and 136 dB, re: 1 microPa). At the 124 dB level of white noise background, both the black drum and Atlantic croaker showed similar changes in auditory sensitivity. However, in the presence of the 136 dB white noise masker, black drum showed significantly greater shifts in auditory thresholds between 300 and 600 Hz. The results indicate that the two species differ in frequency selectivity since the Atlantic croaker was less susceptible to auditory threshold shifts, particularly at the higher level of masking. This difference may be linked to peripheral auditory mechanisms.
Distortion product otoacoustic emission (DPOAE), auditory brainstem evoked response (ABR), and behavioral thresholds were recorded in a group of 15 adult rhesus monkeys with normal auditory function. DPOAE thresholds were recorded with stimulus parameters selected to maximize signal-to-noise ratio. Additional averaging at the lowest frequencies ensured comparable noise levels across frequencies. DPOAE thresholds decreased with increasing frequency (f(2)=0.5-16 kHz) and at 16 kHz were close to 0 dB SPL. ABR thresholds were best from 1 through 16 kHz (32-38 dB peSPL); higher at 0.5 (45 dB peSPL), 24 (39 dB peSPL), and 30 kHz (49 dB peSPL). At all levels including threshold, the early ABR waves (II and I) were more prominent at the high frequencies while the later waves (IV and V) were more prominent at the low frequencies. The behavioral thresholds recorded were similar to those reported by other researchers although elevated by about 10 dB presumably because of the complexity of the threshold task. DPOAE and ABR thresholds can be reliably and efficiently recorded in the rhesus monkey and provide information concerning site of processing in the auditory pathway not directly available from behavioral data.
The auditory abilities of the brushtail possum (Trichosurus vulpecula) have been measured by cochlear potential readings, but no behavioural determinations of their auditory abilities have been published. Six experimentally naive possums were trained to perform a two-response conditional discrimination between the presence and absence of an 880-Hz tone (at 80 dB). All six possums readily learned this task. The behavioural threshold for this tone was determined using a modified tracking procedure and found to be similar to that reported using cochlear microphonic potentials. One concern with the current method was the communal nature of the experimental environment so a further threshold determination in a sound-attenuating chamber was conducted. No substantial difference was noted between the results obtained in the two threshold determinations. The success of the current method means that a full, behavioural audiogram for the brushtail possum, which would complement the existing cochlear potential data, is now possible.
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Using gated sinusoidal stimuli (tone bursts), frequency-specific auditory brainstem responses (ABR) have been recorded in mice. The gating function represents a filter with a constant narrow bandwidth in the investigated frequency range 2-31.5 kHz. The ABR thresholds found in the CBA/CBA mouse using this technique were in close agreement with those previously reported in the literature concerning mice. The ABR thresholds were analysed in 2-18-month-old animals showing a slight impairment of ABR thresholds with increasing age. The individual variations in ABR thresholds were small.
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