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PubMed1980

[State of the ascorbate and thiol-disulfide systems in brain concussions].

As a result of a clinico-experimental study data on the state of the thiol-disulfide and ascorbate systems in the acute period of brain concussion have been for the first time obtained, and the role of those systems in the development of the vegetative disturbances, hypoxia and increased vascular permeability has been specified. A good therapeutic effect from the use of penicillamine in this pathology is demonstrated. It is recommended that the determination of the state of the above systems should be used for observing the treatment efficacy and determining the duration of patients' hospitalization.

Adolescent↗
PubMed1993

[The acute period of brain concussion: the dynamics of the clinical and neuropsychological symptoms].

Analysis of significant correlations between clinical and neuropsychological symptoms in 104 young patients with no anamnesis load, made in the acute period of brain concussion (BC), has demonstrated that the intensity of clinical symptoms correlates with the grade of disorders of higher mental functions (HMF). Besides, significant correlations were discovered between neuropsychological symptoms of brain stem injury and disorders of energy supply to HMF as well as between clinical symptoms of the involvement of the limbic-diencephalic structures and disorders of arbitrary control and emotional disturbances which are determined by the involvement into the pathological process of the anterior parts of the right and left cerebral hemisphere. The dynamic of clinical and neuropsychological symptoms after BC lies in the regression of disorders of stem nonspecific system, diencephalic and limbic structure functions. Toward the end of the acute period the structure of the neuropsychological syndrome is determined by disorders of arbitrary regulation of HMF, which are associated with dysfunction of the mediobasal parts of the frontal lobes, largely of the left hemisphere.

Acute Disease↗
PubMed1993

[Thyroid function in brain concussion].

RIA was used to study the quantitative content in the blood serum of thyrotropic (TTH), thyroid (total thyroxine (T4), free thyroxine, triiodothyronine (T3) hormones and thyroxine-binding capacity of blood plasma proteins in 30 patients with brain concussion from the first to the 12th day of disease. The patients' hormonal profile was characterized by normal characteristics of TTH, depression of the transport organic phase of thyroid metabolism with a decrease of the T4 concentration, a reduction of the thyroxine-binding capacity of plasma protein, and simultaneous activation of the peripheral stage of iodine metabolism with excess accumulation in the blood of active hormones--free thyroxine and T3. The data obtained deepen our understanding of the pathogenesis of craniocerebral injury (CCI). The neuroendocrine syndrome identified is specific for mild CCI. It can be used as a differential diagnostic criterion for expert medical evaluation purposes.

Adolescent↗
PubMed1988

[Brain concussion].

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Brain Concussion↗