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PubMed1984

Intraoperative sonographic delineation of low-grade brain neoplasms defined poorly by computed tomography.

Sixty-four consecutive primary or metastatic brain tumors were reviewed to assess the efficacy of intraoperative sonography for localization, biopsy, and/or drainage. In 12 cases, preoperative CT data were incomplete or confusing, usually due to low-density, non-enhanced areas in which low-grade tumor could not be reliably differentiated from necrosis, edema, or cyst. In each case, intraoperative sonography clarified the nature of the solid tumor component by its distinct hyperechogenicity, facilitating biopsy. As a guide to surgical biopsy of brain tumors, sonography has some advantages even over stereotactic systems, which depend upon accurate CT definition of the lesion.

Adult↗
PubMed2002

Monofocal acute inflammatory Demyelination (MAID): a unique disorder simulating brain neoplasm.

BACKGROUND: Monofocal acute inflammatory demyelinating (MAID) lesions present as large masses that mimic brain tumors. The natural history and nosologic classification are not well defined. METHODS: Five patients with MAID from our files and 4 from the literature are presented. We defined MAID as a mass-like lesion, >4 cm in diameter. Demyelination was pathologically proven in all patients. RESULTS: Headaches and motor deficits were the most common presenting symptoms. Language problems and motor deficits were the most common findings on physical examination. After a median follow-up of 44 months, none of our 5 patients had multiple sclerosis. In similar cases, additional lesions indicative of multiple sclerosis developed within an average of 8 months. CONCLUSIONS: It may be difficult to distinguish MAID from brain tumor. It may be that MAID represents a unique form of isolated demyelinating disease, or it may represent transition to multiple sclerosis.

Adult↗