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[Characteristics of collateral circulation in the ophthalmic artery before and after cerebral revascularization in patients with multiple occlusive diseases of the major arteries of the head].

The status of the collateral blood flow was examined before and after establishment of ++extra-intracranial microarterial anastomosis (EICMA) in 70 patients with occlusion of the internal carotid artery. Of these, 93% of the patients also had lesions of the other main arteries of the head. It has been established that in concomitant lesions of the main arteries of the brain, the role of the ophthalmic artery (OA) rises as to the compensation for the blood flow in the damaged hemisphere. Involvement of the ophthalmic anastomosis into blood supply of the damaged hemisphere was found to inversely correlated to EICMA function. Active functioning of EICMA brings about a decrease of the retrograde blood flow in the OA and in some cases, alteration in the direction of the blood flow in that artery, namely from retrograde to antegrade. Nevertheless additional blood flow via EICMA promotes elevation of the level of the cerebral blood flow in the regions of the middle cerebral artery basin, supplied via the microarterial anastomosis.

Adult↗

Correlation of MRI and CT data with outcome of cerebral revascularization after stroke.

Sixteen patients with the occlusion of the internal carotid artery (ICA) underwent extra-intracranial bypass surgery. All patients had stroke in evolution or completed stroke with mild or moderate (n = 9) or severe (n = 7) neurological deficits. In each case, the clinical course, magnetic resonance imaging (MRI), computed tomography (CT) and angiographic (AG) findings were evaluated. Patients were followed up from 9 months to 2.5 years postoperatively. MRI was much more sensitive than CT for appreciating the ischaemic tissue. The infarct volume determined by MRI had greater extent than previously detected by CT. If the difference of the infarct volume, detected by MRI and CT was more than 30% the patients appeared to have benefited from bypass surgery as demonstrated clinically as well as with postoperative MRI and AG studies. Patients with lesser difference showed insignificant or no postoperative improvement.

Adult↗

Cerebral revascularization during barbiturate coma in primates and humans.

Extracranial-intracranial arterial bypass was performed in five baboons to assess the effectiveness of the procedure in preventing acute cerebral ischemia following middle cerebral artery occlusion in our primate model. Thirty minutes following middle cerebral artery occlusion, the animals were placed in barbiturate coma while the extracranial-intracranial artery bypass was being completed. In the three animals with patent extracranial-intracranial arterial bypasses, infarction was prevented. In the two with occluded extracranial-intracranial arterial bypasses, a large infarction in the territory of the middle cerebral artery occurred. In a clinical correlate, postoperative ischemia was presumably prevented in three patients by barbiturate administration and revascularization for unanticipated intracranial vessel occlusion.

Animals↗

Complex cerebral revascularization.

Although carotid endarterectomy is the usual technique for treating symptoms related to extracranial arterial occlusive disease, cerebrovascular and upper extremity symptoms caused by lesions of the innominate, common carotid, or subclavian orifices necessitate more complex revascularization techniques. We have treated five patients, three females and two males, with symptoms of cerebrovascular and/or upper extremity ischemia by highly individualized, complex, revascularization techniques. The procedures were amalgamations of carotid-subclavian bypass, carotid-subclavian bypass with carotid bifurcation endarterectomy, subclavian-subclavian bypass, axillo-axillary bypass, and carotid-axillary bypass. The conditions of all patients were greatly improved and four of the five patients became asymptomatic. These procedures seem to be highly effective in relieving symptoms and they minimize the risks of cerebral and upper extremity revascularization.

Adult↗

Cerebral revascularization by extracranial-to-intracranial anastomosis.

Four cases are presented in which a superficial temporal artery was anastomosed to the cortical branch of the middle cerebral artery. The surgical technique is described. The indications and contraindications and results of the procedure are briefly discussed by referring to recent publications on the subject.

Adult↗

[Cerebral revascularization by extra-intra-cranial arterial anastomosis. Technique and results (author's transl)].

Extra-intra-cranial anastomosis introduced in 1967 by Yasargil and Donaghy consists in using a branch of the external carotid artery to anastomose it on one of the cerebral cortex. This procedure is indicated when there exists an obliterating lesion not in reach of a local technique. On clinical grounds two situations may exist: --the first is a regressive ischemic episod and the operation is then preventive; --the second is a confirmed deficit, non regressive: thecurative value of such an operation must then be discussed. The author reports his 5 year experience: 51 patients were operated amounting to 60 anastomoses. Eighty percent of the operated patients have a patent anastomosis. The operative risk is small (1 death, 1 worsening). The clinical criteria are discussed (Acta chir. belg., 1979, 78, 85-93).

Adult↗