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[Exogeneous hair damage caused by bleaching and cold waving. A case report with scanning electron microscope studies].

A case of exogeneous hair damage caused by bleaching and cold waving is reported. The clinical picture showed brittle, lustreless, fallow hair. The light microscope showed irregular spreading of the cuticular cells. The scanning electron microscope revealed loss of the regular cuticular pattern, breakage of the edges of the cuticular cells, and wave-like separations of the cuticular cells from the cortex. The hair shafts showed multiple longitudinal indentations like seen on a tree trunk.

Adult↗

[Four cases of pseudothrombocytopenia due to platelet cold agglutinins].

We report 4 cases of pseudothrombocytopenia due to platelet cold agglutinins. Case 1 was a 57 y.o. female whose platelet count was 97 x 10(3)/microl. Case 2 was a 37 y.o. male with a platelet count of 96 x 10(3)/microl. Case 3 was a 74 y.o. male with a platelet count of 28 x 10(3)/microl. Case 4 was a 62 y.o. female whose platelet count was 34 x 10(3)/microl. The platelet counts in these 4 cases were decreased and blood smears showed platelet clumping in blood drawn in a tube without anticoagulant just after withdrawal, as well as in blood drawn in a tube with anticoagulant. The platelets from these patients agglutinated at a temperature below 10 degrees C (case 1 and 4) and 24 degrees C (case 2). The immunoglobulin class of the platelet cold agglutinins in cases 1, 2 and 4 was IgM. Agglutinated platelets showed no activation marker, such as CD62P, CD63 or CD40L, on the surface of the platelets. The target antigen of cold agglutinins was GPIIb-IIIa in cases 1 and 2. We considered that the detection of platelet agglutination in blood without anticoagulant is important to diagnose pseudothrombocytopenia due to platelet cold agglutinins. Although this disease is considered to be very rare, we suspect that this disease may be misdiagnosed as pseudothrombocytopenia due to the presence of an anticoagulant, and overlooked.

Adult↗

"Cold" corneal abscess in psoriasis: a case report.

A single case of "cold: corneal abscess in a psoriatic patient was considered worth reporting as there are no other cases described in the literature. The importance of the correct diagnosis and the management are discussed.

Abscess↗

Paroxysmal cold haemoglobinuria. A case report.

The clinical and biochemical findings in a 35-year-old Black man with paroxysmal cold haemoglobinuria are presented. Particular attention is drawn to the possible triggers of the haemolytic process, and the treatment is briefly reviewed.

Adult↗

Case report: tubercular cold abscess of seminal vesicle: minimally invasive endoscopic management.

BACKGROUND: Tubercular cold abscess of the seminal vesicle is very rare, and only a few cases are reported in literature. Preoperative diagnosis is difficult and to the best of our knowledge has not been reported. CASE REPORT: A 35-year-old man presented with a 7-year history of blood in the semen and a reddish brownish discharge per urethra while defecating. On rectal examination, a soft fluctuant mass was felt above the prostate. Abdominal ultrasonography showed cystic swelling of the right seminal vesicle bulging into the posterior bladder wall. Semen examination showed abundant pus cells and 90% immotile sperm with normal morphology. Acid-fast bacilli were not seen, but acid-fast bacilli were found in a 24-hour urine specimen. Cystoscopy showed tubercles in the urethra and brownish discharge from the orifice of the right ejaculatory duct on per-rectal compression of the mass. The abscess cavity was incised with a Collings' knife. Brownish material was evacuated, and the abscess cavity was seen. An 18F Foley catheter was placed for 3 days. Antitubercular therapy was instituted. Ultrasonography repeated after 3, 25, 45, and 75 days showed gradual regression of the abscess cavity. Semen examination after 75 days was normal, with 75% motility, and cystoscopy 45 days postoperatively showed complete healing of the wound. CONCLUSION: The incision connecting the bladder with the abscess cavity facilitated evacuation of pus and complete resolution of the abscess.

Abscess↗

[Donath-Landsteiner antibody of the IgM class with anti-I specificity and possible efficacy of azathioprine therapy in paroxysmal cold hemoglobinuria: a case report].

In October 1988, a 72-year-old man was admitted to Nagasaki Prefectural Shimabara Onsen Hospital because of hemoglobinuria on exposure to cold. On admission, the laboratory data were Hb 9.1 g/dl, LDH 2,337 U/L, and haptoglobin less than 6 mg/dl. The Donath-Landsteiner (DL) test was positive and serological tests for syphilis were negative. Anti-Coxsackie virus type A9 antibody titer was elevated. Accordingly, he was diagnosed as having paroxysmal cold hemoglobinuria (PCH) associated with viral infection. The DL antibody proved to be of the IgM class having anti-I specificity. The patient was treated unsuccessfully with prednisolone, but hemolysis was improved after azathioprine (AZP) therapy. PCH patients with DL antibody of the IgM class exhibiting anti-I specificity are very rare and only two patients including the present case have been reported in Japan. There has been no report on the efficacy of AZP in PCH, but our study suggests that AZP may have a potential therapeutic effect in some PCH patients.

Aged↗

[Heat-contact urticaria and cold-contact urticaria (case report)].

A 40-year-old female patient has been suffering from localized heat urticaria for 8 years and, in addition, from localized cold urticaria for 1 year. Both diseases could be proved by adequate physical tests. Exposition to localized heat provoked decreased serum complement, suggesting activation of the alternative pathway.

Adult↗

Hand replantation after 54 hours of cold ischemia: a case report.

A number of case reports and series have reported successful replantation after prolonged periods of ischemia. However, the acceptable range of normothermic and hypothermic ischemic storage remains controversial. There is little question that the tolerance of composite tissue for ischemia is dependent on the quantity of contained skeletal muscle. We report a successful hand replantation after 54 hours of cold ischemia. We believe that this case documents the longest anoxic period yet reported for successful hand replantation. We further believe that the functional results obtained confirm the value of hand replantation even after such a prolonged ischemic interval.

Adolescent↗