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At least 109 records · Page 6Linked to original sources
PubMed1993

Does motor cerebral dominance develop secondary to sensory dominance?

Current research and theoretical frameworks for understanding motor dominance assume that motor dominance is primary. Various developmental clues, however, suggest that the maturation of proprioceptive sensory processing predates that of motor control. We hypothesized that the observed adult pattern of lateralized motor dominance may develop as a consequence of preexisting lateralized "sensory" or "proprioceptive dominance." To test whether motor preference could develop in response to sensory dominance, we investigated sighting eye dominance, eye lid winking, and handedness in 164 individuals. Subjects winked the nondominant eye significantly more frequently than the dominant eye and independently of their handedness, lending partial support to the idea that motor function can develop in response to sensory function. Specific investigation of the development of the proprioceptive system would be needed to evaluate whether lateralization of motor handedness develops as a consequence of "proprioceptive" lateralization.

Adult↗
PubMed2002

Familial hypodigoxinemic membrane Na(+)-K(+) ATPase upregulatory syndrome - relation between digoxin status and cerebral dominance.

A family with coexistence of hypotension, recurrent respiratory infection, motor tics, obsessive compulsive disorder, major depressive disorder, early onset osteoporosis, low body mass index, bulimia nervosa and healthy aging with longevity is described. The family members had hyposexual behavior, less tendency for spirituality, had no insomnia but a tendency towards increased somnolence, no addictive behaviour, had more bonding and affectionate behavior and were less creative with an average IQ. There was no vascular thrombosis, systemic neoplasm and neuronal degeneration in the index family. All members of the family were left hemispheric dominant. The level of serum digoxin, HMG CoA reductase activity and dolichol was found to be decreased in all with a corresponding increase in RBC Na(+)-K(+) ATPase activity and serum ubiquinone magnesium level. There was increase in tyrosine catabolites and a reduction in tryptophan catabolites in serum. Total and individual glycosaminoglycan fractions, carbohydrate residues of glycoproteins, glycolipids, activity of GAG degrading enzymes and glycohydrolases were decreased in serum. The concentration of RBC membrane total GAG and carbohydrate residues of glycoproteins increased while cholesterol : phospholipid ratio of membrane decreased. The activity of free radical scavenging enzymes were increased while the concentration of free radicals decreased significantly. The same biochemical patterns were observed in left hemispheric dominance as opposed to right hemispheric dominance. The significance of these findings in the pathogenesis of these disorders is discussed.

Cardenolides↗