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At least 109 records · Page 6Linked to original sources
PubMed1978

[The aberrant pancreas in gastro-duodenal disease. A clinical, endoscopic-bioptic study].

30 instances of aberrant pancreas were noted in 13,620 routine gastroduodenoscopies (0.22%), usually in the antrum or duodenum (antrum 83.5%, cap 6.6%, D2 6.6%). Symptoms, where present, took many forms and were aspecific, since they were related to size and site. The difficulties surrounding conventional methods of diagnosis are explained. Radiology reveals local alteration in 80% of cases, though its offers formally useful data in only 10%. Endoscopy and oriented biopsy partly make up for this inadequancy, because an aberrant pancreas may present as an atypical, nonumbelicated form that cannot be endoscopically distinguished from other benign growths. In addition, biopsy of the pancreas may be difficult in a submucosal site. Given the relative inefficacy of even the most recent techniques, perendoscopic polypectomy is proposed as a means of combining optimum diagnosis and radical treatment.

Adolescent↗
PubMed1998

Effect of Helicobacter pylori eradication on the natural history of duodenal ulcer disease.

BACKGROUND: Duodenal ulcer disease is strongly associated with Helicobacter pylori infection of the gastric mucosa. Eradication of H pylori from the gastric mucosa in adults is associated with long term healing of ulcers. AIMS: To follow a cohort of children with duodenal ulcer disease for a minimum of two years after the eradication of H pylori. PATIENTS AND METHODS: Over a three year period, all children diagnosed with duodenal ulcer disease had their symptoms documented and their H pylori status evaluated. The histories of these children were carefully screened to determine previous symptoms and to document previous treatment regimens. RESULTS: Sixteen children were diagnosed with ulcers and 15 were available for treatment and long term follow up. The median age at which symptoms first occurred was 10.5 years (range, 6-14) and the median duration of symptoms was 24 months (range, 2-60). Ten of the children had been treated with H2 receptor antagonists for a median of 3.5 months (range, 1-60). Duodenal ulcers healed in all children after eradication of H pylori and all children have remained asymptomatic for a median of 37 months (range, 26-62). No child has required subsequent admission to hospital. CONCLUSION: Eradication of H pylori is very effective in the long term healing of duodenal ulcer disease. H pylori eradication should be the standard treatment for all infected children who present with duodenal ulcer disease.

Adolescent↗
PubMed2003

[Surgical treatment of gastric and duodenal ulcer disease with chronic duodenal obstruction].

One hundred and twenty-nine surgeries were performed from 1990 to 2001 for gastric (50) or duodenal (79) ulcers with chronic duodenal obstruction. Resection of 1/2 of the stomach by Bilrot-I was performed in 118 patients, pylorus-saving resection with creation of areflux valve in duodenal bulb--in 5, selective proximal vagotomy with duodenoplasty--in 6 patients. In early postoperative period complications were seen in 10 (10.9%) patients, postoperative lethality was 0.8% (one patient died). There was no insufficiency of anastomotic sutures. Postoperative stay was 11.3 +/- 1.5 days. In remote period after surgery symptoms of chronic pancreatitis was in 2.3% patients, but there were no symptoms of duodenostasis. Roentgenological symptoms of compensated duodenal obstruction were seen in 2 patients operative on for decompensated duodenostasis. These patients had no complaints.

Adult↗
PubMed1979

Endoscopic duodenal biopsies in coeliac disease and duodenitis.

Endoscopic duodenal biopsies were taken from 27 patients with suspected coeliac disease and compared with intubation capsule jejunal biopsies. The specimens were reported without knowledge of the patients' names or symptoms. In 24 patients (89%), coeliac disease could either be diagnosed or excluded with 100% accuracy, despite the inability to orientate the biopsies correctly. Six biopsies were considered technically unsatisfactory, but only in three (11%) was it impossible to exclude coeliac disease. Duodenal biopsies were also taken from 118 consecutive patients attending for routine upper gastrointestinal endoscopy, and 1 patient with coeliac disease was discovered. We conclude that endoscopic duodenal biopsies are a reliable and worthwhile screening test for coeliac disease in certain patients attending for routine upper gastrointestinal endoscopy.

Celiac Disease↗
PubMed2001

[Application of endoscopic laser irradiation and antibacterial therapy in surgical treatment of duodenal ulcer disease].

For duodenal ulcer disease there were performed an isolated selective proximal vagotomy--in 63 patients, vagotomy with various kinds of drainage operations--in 32, gastric resection according to Billroth-II--in 19. The expediency of application of endoscopic laser irradiation and antibacterial therapy in preoperative preparation complex for prophylaxis of early postoperative complications and the ulcer recurrences occurrence was noted. Among the patients operated on without the preoperative preparation conduction the inflammatory complications in early postoperative period occurred in 19.3% of them and the ulcer recurrence--in 11.5%; after preoperative preparation conduction--in 8.6 and 4.8% accordingly.

Adult↗
PubMed2002

[Acid-forming stomach function and characteristics of reflux disorders in patients with bile stone disease and duodenal ulcer combination].

Results of examination of patients suffering from cholecystitis combined with duodenal ulcerative disease and accompanying duodenogastric reflux are presented. The comparison of acidifiable gastric function state in patients suffering from cholelithiasis combined with duodenal ulcerative disease and patients with only cholecystitis or duodenal ulcerative disease was performed. Intragastric pH-metry allows not only to study acidifiable gastric function but also to reveal functional disorders like duodenogastric reflux. Expressed and resistant duodenogastric reflux can result in structural modification of gastric mucosa.

Aged↗
PubMed1975

Duodenal obstruction related to benign biliary tract disease.

Duodenal obstruction in six patients was related to biliary tract disease and previous abdominal surgery. Causes of obstruction were adhesions to the inflamed gallbladder, adhesions to the gallbladder bed after cholecystectomy, intramural hematoma after transduodenal exploration of the common bile duct and severe pancreatitis after common bile duct exploration. Measures that may possibly prevent duodenal obstruction include early recognition and treatment of cholelithiasis, positioning of omentum between duodenum and gallbladder bed after cholecystectomy, avoidance of transduodenal exploration where possible and careful duodenal closure if necessary, avoidance of forceful dilation during common bile duct exploration, and a decrease in the number of negative explorations by increased use of cystic duct cholangiography

Adult↗
PubMed1990

Gastric enterochromaffin-like (ECL) cells in hypergastrinaemic duodenal ulcer disease.

Patients with hypergastrinaemic duodenal ulcer disease were studied to determine whether chronic moderate hypergastrinaemia produces hyperplasia of gastric enterochromaffin-like cells in man. Eight patients had peak postprandial plasma gastrin concentrations greater than 200 pmol/l, which is the 92nd percentile for patients with duodenal ulcer disease in this laboratory. The control group was eight patients with duodenal ulcers whose peak postprandial gastrin concentrations were less than 200 pmol/l. Basal and peak postprandial plasma gastrin concentrations were 107 (37) and 306 (66) pmol/l (mean (SEM] respectively in the hypergastrinaemic patients compared with 26 (4) and 137 (14) pmol/l respectively in the controls. There was no significant difference in the density of gastrin enterochromaffin-like cells between the two groups. The number of enterochromaffin-like cells per high power field was 53 (8) in the hypergastrinaemic patients compared with 50 (8) in the controls. We conclude that chronic moderate hypergastrinaemia does not produce hyperplasia of enterochromaffin-like cells in man. Our hypergastrinaemic group had plasma gastrin concentrations similar to, or greater than those reported during treatment with drugs such as omeprazole and histamine H2 receptor blockers.

Adult↗