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Regional enteritis in children: small bowel disease with normal terminal ileum.

Regional enteritis in children may affect the small bowel without involvement of the terminal ileum. We have noted this distribution of disease in 4 of 20 consecutive cases of Crohn's disease. The clinical and radiologic features of these 4 patients are reported together with a review of similar observations in the literature.

Adolescent↗

Borderlands in the diagnosis of regional enteritis: trends in overdiagnosis and value of therapeutic trial.

Our regional experience in the state of Connecticut indicates that Crohn's disease is being overdiagnosed. Six patients with disorders mimicking regional enteritis are presented, one of whom had an atypical clinical course and the remainder had atypical therapeutic responses. The radiologist should be aware of clinical responses and make reassessments if necessary, in order not to overlook surgically treatable conditions.

Adolescent↗

Sarcoidosis and regional enteritis in two patients.

Both sarcoidosis and Crohn's disease (regional enteritis) are characterized by granuloma formation and they also have an unknown etiology. Only a few subjects with co-existing sarcoidosis and Crohn's disease have been reported in the literature. We report two cases who suffered from both disorders. In the two subjects Crohn's disease began first and the symptoms of sarcoidosis came later; four and sixteen years, respectively.

Adolescent↗

Reoperation for regional enteritis (Crohn's disease).

Twenty-five patients had major operations for regional enteritis between 1969 and 1981. Of these, 12 patients required subsequent major procedures for recurrent disease. This group consisted of three men and nine women who were operated upon a total of 32 times. Their average age at onset of disease was 27.4 years, compared with 40 years for those patients who were operated upon only once. The reoperated group had an average of 3.5 nonoperative hospital admissions, while, patients in the group with one operation were hospitalized 1.8 times for disease during the period studied. Identification of operated patients who will require reoperation would improve counseling of these patients. Earlier age of onset and more frequent nonoperative admissions seem to be associated with need for reoperation. Extent and type of primary resection seem to be of less predictive value.

Adult↗

Systemic sclerosis and regional enteritis occurring simultaneously.

A 58-year-old white female who had regional enteritis for many years insidiously developed scleroderma. A review of the literature failed to reveal any previous reports of this combination of diseases. The possible etiologies of both diseases are discussed along with their overlapping clinical manifestations.

Colostomy↗

Folic acid absorption in regional enteritis.

The authors have investigated intestinal absorption of folic acid by jejunal perfusion with a triple lumen tube in five subjects with regional enteritis. The subjects' intestinal disabilities ranged from terminal ileitis to short bowel syndrome. Two had steatorrhea and two had low serum folate levels. Absorption of pteroylglutamic acid was normal in all five. This suggests that folic acid deficiency, common in this disorder, is largely caused by malnutrition, not malabsorption.

Adult↗

Regional enteritis leading to carcinoma of the small bowel.

A case of carcinoma of the small bowel intimately associated with long-standing regional enteritis (Crohn's disease) is described. Sixteen similar cases reported in the literature are briefly reviewed. This neoplasm presents at a younger age than other small bowel carcinomas and there seems little doubt that it is causally related to the inflammatory bowel lesion.

Adenocarcinoma↗

Calcified enteroliths in regional enteritis.

A case of enterolith formation in a dilated pre-stenotic segment of the ileum in a patient with long existing regional enteritis is presented. Recognition of abdominal calculi as enteroliths may represent the diagnostic clue to the presence of chronic stenosing disease of the lower intestinal tract.

Aged↗

Voodoo in the general hospital. A case of hexing and regional enteritis.

We have observed the case of a hexed patient that emphasizes the interplay between modern medical practice and the influence of a supernatural voodoo subculture. Psychosocial stresses involved in the patient's illness (regional enteritis) added to the complexity of the clinical problem. The presence of ambivalence in the patient and her mother concerning their systems of belief, and their unwillingness to accept totally the treatment modalities of either modern medicine or voodoo, probably prevented the patient's predicted death.

Adult↗

Pyoderma gangrenosum associated with regional enteritis. Improvement in defective granulocyte function and healing of skin lesions during administration of clofazimine.

A defective uptake of oxygen by peripheral blood granulocytes during phagocytosis, indicating a subnormal phagocytic capacity, has been found in a patient with regional enteritis complicated by pyoderma gangrenosum (PG). During administration of clofazimine and granulocyte function normalized and the skin lesions healed. It is possible that a defective granulocyte function may sometimes be involved in the pathogenesis of PG and that a clofazimine-induced improvement in the function will favour healing of the lesions. The result of treatment in our patient and in other cases recently published indicates that the drug may be worth trying in PG.

Adult↗

[Is there a connection between infection with Yersinia enterocolitica and regional enteritis? (Preliminary communication) (author's transl)].

After a brief description of the micro-biological, pathological, anatomical and clinical picture of infections with Yersinia enteroclitica, attention is drawn to the striking radiological similarity between three patients with Yersinia infection and regional enteritis (Crohn's disease). Whilst the radiological findings due to Yersinia infection usually resemble the group of so-called non-sclerosing ileitis (Golden) they occasionally differ from this group and resemble the findings in Crohn's disease. In each case the infection was confirmed bacteriologically. The underlying pathology has not been elucidated and it is doubtful whether there is any connection with Crohn's disease.

Adolescent↗

[Yersinia enterocolitica in acute appendicitis, lymphadenitis mesenterialis and regional enteritis (author's transl)].

In 895 patients operated on for acute appendicitis we found Yersinia enterocolitica in 41 cases. Another two cases were detected in postoperative serological examinations. Lymphadenitis mesenterialis was present in 17 cases during operation. Once we detected a regional enteritis. Histological examination of the appendix revealed a purulent inflammation in 21 cases and a phlegmonous-gangrenous inflammation in 4 cases. The other 18 patients suffered from Oxyuriasis, coprostasis or scars of the appendix. For this reason it is impossible to exclude an acute appendicitis in patients with cultural or serological identification of Yersinia enterocolitica.

Acute Disease↗

Vitiligo associated with regional enteritis.

Although the cause of vitiligo is unknown, there is considerable evidence to indicate that autoimmunity plays a role. Much of this evidence is based on the increased associated occurrence of vitiligo in a number of diseases also believed to be autoimmune in origin. I have observed a case of almost simultaneous onset of vitiligo and regional enteritis. A search of the literature revealed no specific case report associating these two disorders. The association of these two disorders in the same person may be more than fortuitous, since both diseases may be autoimmune in origin.

Adult↗