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At least 109 records · Page 6Linked to original sources

Treatment of facial muscles affected by Bell's palsy with high-voltage electrical muscle stimulation.

OBJECTIVE: This report discusses high-voltage electrical muscle stimulation and chiropractic manipulation used to treat two patients who suffered from Bell's palsy. CLINICAL FEATURES: Case A: A 15-yr-old with left sided facial palsy was seen 2 days after the onset of symptoms. Upon observation, the left upper and lower eyelids were drooping and the left eye had excessive tearing. Motion palpation indicated multiple fixations in the cervical spine. Laboratory studies showed a microcytic anemia. A clinical diagnosis of Bell's palsy (House-Brackmann Grade V) and microcytic anemia was made. Case B: A 17-yr-old with left sided facial palsy was seen 8 days after onset of symptoms. Upon observation, the patient showed left sided facial paralysis and an inability to close the left eye completely. Motion palpation indicated multiple fixations in the cervical spine. A clinical diagnosis of Bell's palsy (House-Brackmann Grade V) was made. INTERVENTION AND OUTCOME: Both patients were treated with high-voltage pulsed galvanic current at 80 peaks/sec with a 7-inch hand-held held probe for 10 min each visit. In addition, the cervical spine fixations were mobilized using chiropractic manipulation. Case A was resolved after 6 wk of treatment and case B was resolved after 3 wk of treatment. CONCLUSION: Both patients benefited from these procedures with complete resolution of symptoms. The techniques outlined should be used at an early stage to accelerate progress toward normal facial muscle function.

Adolescent↗

Unusual synkinetic movements between facial muscles and respiration in hemifacial spasm.

We describe two cases of hemifacial spasm (HFS) with unusual synkinetic movements between facial muscles and respiratory activity. Patient 1 developed an idiopathic HFS. She underwent microvascular decompression surgery, followed by transitory facial nerve palsy; she recovered but later developed a facial synkinesia characterized by involuntary and forced eyelid closure on spontaneous and deep breathing; the orbicularis oculi muscle was active also when her mouth was open (the so-called Marin-Amat syndrome). Patient 2, 1 year after a peripheral facial nerve palsy (Bell's palsy), developed an HFS together with synkinetic movements between the orbicularis oculi muscle and respiration. In both cases electrophysiological studies showed pathological synkinetic electromyographic activity. An enhanced hyperexcitability of brain stem interneurons and facial motoneurons could be suggested to explain the phenomenon.

Aged↗

Facial muscle patterning to affective imagery in depressed and nondepressed subjects.

When subjects imagine happy, sad, and angry situations, different patterns of facial muscle activity are produced which can be measured by electromyography. These subtle, typically covert, facial expression patterns differentiate depressed from nondepressed subjects. Facial electromyography can provide a sensitive, objective index of normal and clinical mood states.

Depression↗

Patterns of involvement of facial muscles during epileptic and nonepileptic events: review of 654 events.

We reviewed the patterns of involvement of the orbicularis oculi and other facial muscles during 654 events recorded in 257 patients undergoing telemetry evaluation. Four hundred fifty-seven episodes represented epileptic seizures and 197 represented psychogenic seizures. Eyes were wide open in more than 90% of patients during the tonic phase of a generalized tonic clonic seizure. Lowering of the lid with partial closure of the eye, without contraction of the orbicularis oculi, was the predominant form of eye closure we observed. Eye closure in any form was uncommon during the ictal stage of epileptic seizures with motor accompaniment and occurred in 21 of 408 cases and in 2 of 49 simple partial seizures somatosensory type. Sustained, forceful eye closure with active opposition to opening was present in 41 of 75 cases of psychogenic seizures with motor symptoms and in 16 of 21 cases of psychogenic unresponsiveness and was much less common with psychogenic seizures with pure sensory symptoms (8 of 72 cases). The mouth is usually wide open during the tonic phase of a generalized convulsion. The presence of a clenched mouth during a "tonic spell" should raise the possibility of psychogenic seizures. Injuries to the tongue due to biting during the epileptic seizures usually affect the side of the tongue. Biting of the lip or tip of the tongue was not seen with epileptic attacks and is also suggestive of psychogenic seizures.

Electroencephalography↗

Distribution of sensory ganglion cells innervating facial muscles in the cat. An anatomical study with the horseradish peroxidase technique.

The question of a possible sensory component in branches of the facial nerve innervating facial mimetic muscles in the cat was examined by the technique of retrograde axonal transport of horseradish peroxidase (HRP). HRP was applied to the proximal cut end of facial nerve branches innervating different facial muscle groups. Following survival periods of 71-75 h the animals were fixed by perfusion. Certain craniospinal sensory ganglia and the brain stem were processed histochemically for demonstration of HRP. HRP-labelled cell bodies, structurally resembling sensory neurons, were consistently observed ipsilaterally in the geniculate and proximal vagal ganglia and under certain conditions in the trigeminal ganglion. Measurements of HRP-labelled neurons in the geniculate and proximal vagal ganglia showed a wide size range but a unimodal size distribution with peaks in the small size range. These findings support the view that facial nerve branches innervating the mimetic muscles contain different types of sensory fibers.

Animals↗

Morphological changes of denervated and reinnervated rat facial muscle.

In 25 rats the facial nerve was resected on the right side and in another group of 30 rats the right facial nerve was transected and immediately repaired with an end-to-end anastomosis. Both groups were subdivided into groups of five rats. Size and histochemical profile of single muscle fibres were analysed by computer-assisted quantification on the basis of their myofibrillar ATPase (pH 4.3) and succinate dehydrogenase activities in serial cross-sections of the levator labii muscle at 7, 14, 21, 28 and 90 days after nerve resection and 7, 14, 21, 28 and 180 days after immediate anastomosis. Seven muscles of four normal rats were used as a control group. Four muscle fibre types could thus be functionally identified: (a) slow oxidative (SO); (b) fast oxidative glycolytic (FOG); (c) fast glycolytic (FG); and (d) succinate dehydrogenase intermediate (SDH-Int). The cross-section of the FOG fibres showed no changes following permanent denervation. while in comparison there was a significant reduction in the cross-section of FG and SDH-Int fibres. After immediate anastomosis no reduction in the cross-section of the FOG fibres was observed. In contrast the cross-section of FG and SDH-Int fibres showed a significant decrease following direct anastomosis and returned to normal levels at 90 days. Neither resection nor end-to-end anastomosis led to significant alterations in the incidence of FOG and FG muscle fibres over the period of evaluation. Changes in fibre size were transient and completely reversible 180 days after nerve repair, whereas fibre type composition was not. These findings may reflect a long-lasting impairment of the precise function of the levator labii muscle after immediate anastomosis.

Adenosine Triphosphatases↗

Sensory evoked facial muscle electromyography for the quantification of acute labor pain.

Assessment of the adequacy of epidural analgesia for acute pain management can be difficult on occasion. This investigation used non-invasive sensory evoked facial muscle electromyography (SEFE) as well as a Verbal Assessment Scores (VAS) to assess severe pain in healthy parturients during the first stage of active labor. Institutional Review Board approval and patient informed consent were obtained from 12 healthy parturients who were in active labor and who had requested epidural analgesia for labor pain. SEFE microvoltage was recorded prior to epidural placement when a patient reported severe pain and again when a patient reported no pain with a subsequent uterine contraction. VAS assessments (0 = no pain and 10 = the worst pain ever experienced) were also recorded at identical time intervals. Statistical analysis was done using the paired two tailed Student's t-test. Each patient served as their own control. A statistically significant decrease in SEFE microvoltage (p < 0.001) was noted when analgesia was established (VAS = 0) in each patient. It was concluded in this pilot study that SEFE can be effective in quantifying acute severe nociception and thus can provide a continuous objective indicator of the effectiveness of analgesic regimens in an acute obstetric pain setting. Its applicability in other acute pain areas remains to be investigated.

Acute Disease↗

Habituation of facial muscle responses to repeated food stimuli.

We have shown in a series of studies that the human salivary response habituates to repeated presentation of gustatory cues. Parallel animal research has shown that mouthing and food acceptance also habituate. Facial expressions represent a complex response pattern in animals and humans that may provide an objective measurement of motivation to eat. The current study assessed whether facial muscles (orbicularis oris region, risorius region, and zygomaticus region) that regulate mouthing habituate to repeated presentations of a small amount (3 kcal) of a pleasant tasting food stimulus. Participants were randomly assigned to groups that received ten presentations of the same or changing taste stimuli. Following these trials all subjects were presented a novel dishabituating stimulus followed by the habituating stimulus. Integrated facial electromyography EMG responses over each region were measured for a 50 second period following the taste stimulus. Results showed differential habituation rates across the two groups, with participants in the repeated taste group showing decreases in contrast to the changing taste group who did not decrease. The participants in the repeated taste group showed dishabituation of these responses. These results systematically replicate basic animal research, and extend the number of responses related to eating in humans that habituate to repeated food presentations.

Adolescent↗

DNA-fragmentation and expression of apoptosis-related proteins in experimentally denervated and reinnervated rat facial muscle.

Muscle fibres may undergo apoptotic cell death in several neuromuscular disorders such as denervated muscle fibres in spinal muscular atrophies. We investigated DNA-fragmentation (in situ by the TUNEL-method) and expression of apoptosis-associated proteins in experimentally denervated and reinnervated rat facial muscle up to 24 weeks after surgery to evaluate the rate and time lapse of apoptotic muscle fibre loss. While denervated muscle displayed constantly high rates of DNA-fragmentation, denervated and immediately reinnervated muscle showed a distinct decrease of primarily elevated DNA-cleavage, finally resembling rates of normal controls. Denervated muscle fibres revealed strong immunoreactivity of the anti-apoptotic proteins bcl-2 and bcl-xL, and the pro-apoptotic factor bax. In reinnervated muscle fibres, only bcl-2 was constantly upregulated while bcl-xL and bax diminished after the 7th week. The present findings indicate that denervation may prompt muscle fibres to activate an intrinsic 'suicide' programme to undergo apoptosis. High levels of bcl-2 after denervation may sustain cell survival until reinnervation, e.g. after accidental nerve damage or in neurodegenerative disorders. Furthermore, increasing levels of bcl-2 are able to neutralize high apoptosis-promoting bax levels. Interventions modifying DNA-fragmentation and the expression of apoptosis-related proteins may lead to new therapeutic concepts in denervating disorders of muscle in the absence of other primary therapies.

Animals↗

Objective assessment of opioid action by facial muscle surface electromyography (SEMG).

1. Activity of the mimetic muscles of the upper face were recorded from awake and anesthetized patients by surface electromyography (SEMG). 2. High amplitude SEMG accompanied ketamine anesthesia and/or the presentation of pain-provoking stimuli. 3. During periods of elevated facial muscle activity, fentanyl or butorphanol decreased SEMG amplitude. 4. The opioid-induced SEMG depression was not consistently associated with either lowered vigilance or analgesia but did provide an objective measure of drug effect.

Adult↗