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Results for “GANGLIA, SPINAL”

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At least 109 records · Page 6Linked to original sources
PubMed1977

[State of the nerve cells of the cat spinal ganglia transplanted into the mesentery].

The survival of the mature differentiated neurons from the spinal ganglia under the conditions of autotransplantation into the colon mesentery of the cat was studied in chronic experiments. For two months, one-third of the neurons from the peripheral parts of the grafts survived and, as the normal ones, had a pseudounipolar form. However, their initial glomeruli had excessive overgrowth in the form of perivascular plexus, in its formation both the main axonal segment with its fine lateral branches and the finest offshoots from the neuronal bodies take part. These regenerating nerve fibres together with growth cones make terminals in the form of buttons, rings and loops. Such terminal structures in the capsular plexus around the neurons and in numerous Nageotte's cells present receptor terminals which are abundantly produced under the condition of the spinal ganglia transplantation.

Animals↗
PubMedDate not supplied

[Topographo-anatomic interrelationships between the branches of the lumbar arteries and the spinal ganglia, nerves and roots].

By using a complex of investigation methods variants of branchingout of the spinal cord and spinal ganglia blood supply sources and their anatomo-topographic interrelations were discerned in 140 preparations of lumbar spinal ganglia obtained from human cadavers of both sexes and different age. With the help of anastomoses these sources form a specific arterial circle around the ganglion. The radicular arteries are noted to be non-equivalent. The annular architectonics of the blood vessels is considered as a morphological manifestation of a functionally reliable blood supply to the border area between the central and peripheral divisions of the nervous system.

Arteries↗
PubMed1985

Distribution patterns of orthogonal arrays and alkaline phosphatase in plasma membranes of satellite cells in rat spinal ganglia.

The plasmalemmal structure of satellite cells in the lumbar spinal ganglia of rat was examined by freeze-fracture and by a cytochemical method for the demonstration of alkaline phosphatase activity. Plasma membranes of satellite cells are the only ones in the ganglia to contain, in addition to globular intramembrane particles, orthogonal arrays of particles 6-7 nm in diameter. The arrays are most concentrated in the portions of the membranes contacting the basal lamina, or outer membranes; they decrease considerably in number in lateral membranes, and are rare in the membrane regions adjacent to the neuronal perikaryon, or inner membranes. Such gradual decrease in array density in satellite cells suggests regional differences of plasma membrane properties within the same cell. Alkaline phosphatase, which was chosen as a cytochemical marker for membrane activity because of its relation to transport function, localizes to inner and lateral membranes, and not to outer membranes of satellite cells. The absence of correlation between localization of orthogonal arrays and such enzymatic activity suggests that the membranes provided with many arrays possess some characteristics different from other membranes that may exclude transport activity. The possible significance of orthogonal arrays and their close association with the basal lamina are discussed.

Alkaline Phosphatase↗
PubMedDate not supplied

Analysis of two types of dopaminergic responses of neurons of the spinal ganglia of rats.

It was established, in experiments on isolated spinal ganglia of adult rats in conditions of intracellular recording, that dopamine (1 microM/liter) elicits depolarized responses in 61% of neurons, hyperpolarized in 20% of neurons, and depolarized-hyperpolarized in 19% of neurons. The depolarized responses are associated with the activation of D1 dopamine receptors, and are governed by the shift of cAMP-dependent cation (sodium) channels to the conducting state. The hyperpolarized responses are triggered by the activation of D2 dopamine receptors, which by means of HTP-binding protein convert the potassium channels to the conducting state. The change in the polarization of neurons with the action of dopamine influences their electrical excitability variously.

Action Potentials↗
PubMed1987

[Morphological picture of the spinal ganglia in guinea pigs exposed to general vibration].

In the spinal ganglia of guinea pigs exposed to general vibration of 40 Hz frequency and 1 mm amplitude for 3 hrs daily, gradually increasing morphological lesions were found after 7, 14, 30 and 90 days of the experiment. The animals exposed to vibration for up to 30 days exhibited a decrease in the cell nuclei volume, increase in the occurrence of eccentric and marginal cell nuclei and nucleoli, as well as an increase in the number of multiple nucleoli. After 90 days' exposure, such severe lesions as tigrolise, vacuolar degeneration of the cytoplasm, granular disintegration of the myelin sheaths or proliferation of glial cells were found.

Animals↗
PubMed1983

[Histomorphogenesis of spinal ganglia developing on the chorioallantoic membrane].

The aim of the present research is to study the development of spinal ganglia implanted onto chorio-allantoic membrane (CAM), where they are supplied by 'foreign', extraembryonic vessels. Small blocks including a segment of the neural tube and 4 pairs of somites were isolated from the brachial or thoracic or lumbar region (neuromeres C13 - T1 or T3 - T6 or L1 - L4) of thirty 3-day donor chick embryos and grafted on the CAM of as many 10-day host chick embryos. At regular time intervals after grafting, the implants were fixed, embedded in paraffin, serially cross-sectioned and stained. The preliminary results are similar for the ganglia from the 3 regions: they seem to indicate that in the spinal ganglia grafted on the CAM the developing blood vessels do not exert any morphogenetic influence on the substratum; this corroborates results from previous researches (2) on the normally 'in situ' developing ganglia. It is now the author purpose to submit to a careful analysis a datum from the present research: namely, the earlier appearance of the endoganglionic vessels in the brachial and lumbar grafted ganglia than in the thoracic ones.

Allantois↗
PubMed1990

[The change of ACh metabolism in the dorsal horn of spinal cord and spinal ganglia during electroacupuncture analgesia (EAA)].

In this paper a preliminary study was made about the relationship between ACh and the primary input of acupuncture sensation based on the changes of content of ACh, its synthetic enzyme (choline acetylase, or ChAC) and its degradation enzyme (acetylcholinesterase, or AChE) in the dorsal horn of the spinal cord and spinal ganglia. The results were found that: 1) EA at "huantiao" exerted a marked analgesia effect, the acupuncture analgesia was inhibited when the lateral dorsal root was cut off. 2) The content of ACh of the EA group were slightly lower than those of the control group. 3) AChE activity in the spinal ganglia and the dorsal horn increased markedly under electroacupuncture stimulation. 4) The activity of ChAC in the dorsal horn of rats under acupuncture stimulation was significantly higher than those of the control group. 5) ACh content in the spinal ganglia increased obviously when the degradation of peripheral ACh was inhibited by prostigmine. 6) With the lumber dorsal roots excised, AChE activity of the operative side were much lower than those of the intact side during EA stimulation. It suggest that the metabolism of ACh in the dorsal horn of the spinal cord and spinal ganglia change during the course of EAA, and only when signals produced at the acupoints are delivered to the spinal cord via ACh-containing primary somatosensory nerves, can they exert analgesic and therapeutic effect of acupuncture.

Acetylcholine↗