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[Study of the efficacy and tolerance of Iopamiron 370 compared to Telebrix Hystero in hysterosalpingography].

Hysterosalpingography is used to study the state of the uterine cavity as well as to analyse the patency of the tubes and the state of the tubal mucosa. It is difficult to find a contrast medium that has both the ideal qualities, be well tolerated and able to show fine pictures that have good contrasts, while at the same time are sufficiently viscous to allow up examination. The contrasts products that are used to carry out hysterosalpingography are often classed as viscous (Telebrix Hystero) and fluid (Iopamiron). This prospective randomised study compares local tolerance and efficiency of the two products. Fifty patients had Iopamiron and 48 Telebrix Hystero in July 1988 and February 1989. There was a statistical difference between the two groups which was significantly in favour of Iopamiron on the following features: Pain as noted on a questionnaire with steps of five points each (p = 0.02), Pain as described by the patient immediately after the examination on a visual analogue scale with p less than 0.01. Overall appreciation of the two products according to their tolerance and the efficiency of the products, which is to say the clearness of the pictures obtained with a p = 0.05.

Consumer Behavior↗

[Evaluation of the radionuclide hysterosalpingography].

In 22 patient in control for sterility and in 6 healthy women the Radionuclide Hysterosalpingography was used and its results were compared to classic Hysterosalpingography and laparoscopy. This new method allows the diagnosis of functional obstructions, reanastomosis and evaluation of the tubal sterilization.

Adult↗

[Use of a nonionic contrast medium (Omnipaque 350) in hysterosalpingography. A comparison with ionic contrast media].

The comparative adequacy was investigated of a nonionic contrast medium (iohexol) versus the ionic contrast medium usually employed in hysterosalpingography. The contrast radiologic features and the radiodiagnostic possibilities of both cm are definitely good. The nonionic contrast medium diffuses quickly and causes the uterine cavity to expand less than ionic contrast media do, thus allowing a better depiction of mucosal and/or parietal pathology. Moreover, nonionic cm allows tubal patency and peritoneal diffusion to be clearly demonstrated, particularly in uncertain cases. As compared to ionic cm, Iohexol did not cause any side effects, except for a mild discomfort. Our results lead us to suggest the use of nonionic contrast medium as the routine contrast medium in hysterosalpingography.

Adult↗

Intravasation during hysterosalpingography using oil-base contrast medium--a second look.

Hysterosalpingography is a study performed commonly to assess the upper reproductive tract in infertile women. A risk with hysterosalpingography is either lymphatic and/or venous intravasation with or without embolization. Of 593 consecutive hysterosalpingograms performed with a low-viscosity oil-base medium, intravasation occurred in 41 cases (6.9%). Embolization was documented in six patients. There were no recognized adverse sequelae from either intravasation or embolization. Intravasation was frequently associated with pathology of the upper genital tract, and suspected tubal occlusion was the most common abnormality detected. Proper timing of the procedure and avoidance of excessive instillation pressure will diminish the incidence of this complication. The use of both a low-viscosity oil-base medium and high-resolution fluoroscopic image intensification may increase the detection of intravasation.

Contrast Media↗

Electronic fluorography for the performance of cine hysterosalpingography.

We used electronic fluorography to perform hysterosalpingography in 25 women with infertility or abnormal bleeding. In contrast to the conventional modality of fluoroscopy with intermittent permanent imaging, an image intensifier was used to periodically record dye injection on a moving tape (cine hysterosalpingography). The mean number of electronic fluorographs taken per patient was 10.8 +/- 3.12 (mean +/- SD). The mean radiation exposure per patient for electronic fluorography was 113.4 +/- 52 versus 112 +/- 52.4 mR when a single conventional radiographic image was taken. We conclude that electronic fluorography is a simple yet accurate radiographic method that delivers to the gonads approximately one-eleventh the dose of ionizing radiation that current standard techniques do, and should be accepted as an alternative diagnostic modality.

Cineradiography↗

[Information obtainable from hysterosalpingography and laparoscopy and importance of tubal factor in sterile patients (author's transl)].

Hysterosalpingography was used in 437 instances and laparoscopy in 99 to check 455 women for tubal patency who come to seek special advice for sterility. Hysterosalpingography was used together with laparoscopy, the latter second in time, on 81 women. Findings agreed in 64.2 per cent and differed in 35.8 per cent. Tubal occlusion was recorded from 106 patients (23.3 per cent). They were unilateral in 70 cases (66.04 per cent) and collateral in 36 cases (33.96 per cent). Thirty-one of the latter 106 women (29.24 per cent) with unilateral or collateral tubal occlusion turned pregnant. Yet, pregnancy occurred only to five of the above 36 women with collateral occlusion. The causes of those apparent tubal occlusions are discussed.

Fallopian Tube Diseases↗

[Prone position in hysterosalpingography].

The authors discuss the importance of prone hysterosalpingography to the aim of a careful tubal examination. Nearly all the complete or partial tubal obstructions, observed during supine hysterosalpingography, have been resolved by the simple prone position. The high percentage (91%) of successes, without pharmacological help, recommends the routine use of this simple method in all cases of doubtful tubal obstructions.

Fallopian Tube Diseases↗

Hysterosalpingography: a technique to aid in assessment of reproductive fitness of female squirrel monkeys (Saimiri sciureus).

A hysterosalpingography method was developed to examine the uterine cavity and oviducts of potential additions to our squirrel monkey breeding colony and those animals within the colony with a history of infertility. Females to be examined were anesthetized and placed in dorsal recumbency. A needle was inserted transabdominally into the body of the uterus, the cervix was sealed with a clamp applied vaginally, and water soluble contrast media was infused into the uterine cavity with sufficient pressure to fill the oviducts. Radiographs were obtained during infusion resulting in visualization of the uterine cavity and the lumina of the oviducts. The ovaries were visualized as they were surrounded by contrast media draining from the fimbriae of the oviducts. Hysterosalpingography proved to be a useful method for clinical evaluation of reproductive potential of female squirrel monkeys. It also has provided a means to diagnose causes of infertility associated with dysfunction of the oviducts.

Animals↗

Hysterosalpingography in cynomolgus monkeys.

This paper describes recent success in performing hysterosalpingography in cynomolgus monkeys. The animals were anesthesized, and a needle was manipulated through the cervical canal into the endometrial cavity for injection of contrast material. Difficulties in threading the needle through the canal were due to several blind pouches formed by folds in the cervical mucosa. The uterine lumen and both tubes could be visualized in over 75% of the cases. The study demonstrates that the hysterosalpingography technique can be performed satisfactorily in cynomolgus monkeys.

Animals↗

Comparative study: Endografine (diatrizoate), Vasurix polyvidone (acetrizoate), Dimer-X (iocarmate) and Hexabrix (ioxaglate) in hysterosalpingography.

Side effects of hysterosalpingography with Dimer-X, Hexabrix, Vasurix polyvidone and Endografine in 142 consecutive patients, receiving one of the four tested media were evaluated from replies to postal questionnaires. The Dimer-X group had a higher incidence of nausea and dizziness. The Endografine group had a higher incidence of abdominal pain. These differences occur especially in the age groups under 30 years. Hexabrix and Vasurix polyvidone are considered the best contrast media for hysterosalpingography and perhaps because of its low toxicity Hexabrix should be preferred.

Abdomen↗

Intravasation during hysterosalpingography using oil-base contrast media.

The use of oil-base contrast media for hysterosalpingography provides detailed imaging and the added information of a delayed film. Intravasation with possible embolization of oily media is often cited as a morbid complication. There are reports of significant morbidity associated with the use of high-viscosity oil media such as Lipiodol. Ethiodol has a significantly lower viscosity than Lipiodol. The incidence of intravasation can be reduced by proper timing of the study and avoidance of excessive pressures during instillation. With fluoroscopy, the early manifestations of intravasation can be detected, allowing the operator to limit the volume of embolized medium. We report 13 cases of intravasation (6 with embolization) with no morbidity during hysterosalpingography performed with Ethiodol. These data suggest that embolization of low-viscosity oil contrast media in low volumes is a relatively benign process. The text of this paper contains data on the clinical histories and courses of the 13 cases cited.

Blood Vessels↗

Intracervical placement of catheter balloon at hysterosalpingography.

OBJECTIVE -- To describe the technique of hysterosalpingography with endocervical placement of the balloon of the catheter rather than endometrial placement. PATIENTS -- 48 consecutive patients undergoing hysterosalpingography in the course of infertility work-up at a university hospital. METHOD -- With the patient in the lithotomy position, the cervix is visualized and cleansed. The catheter and balloon are inserted in the cervical canal and inflated with the contrast agent. The contrast agent is injected slowly at low pressure, and three to six spot films are obtained. Only gentle traction can be applied by this method, so oblique views are obtained early in the examination. RESULTS -- Balloon placement was atraumatic. Although good views were obtained more frequently than with traditional techniques, about one-quarter of the studies were unsatisfactory. CONCLUSION -- This method is easy, atraumatic, and allows excellent visualization of the entire endometrial cavity and upper intracervical canal.

Catheterization↗

[Contrast hysterosalpingography (or HyCoSy)].

A new echogenic contrast medium, SHU-454 is a new method for direct imaging of fallopian tube passage in tubal diagnostics using transvaginal B-mode echography. Clinical studies in over 1,600 patients have shown that this product offers a reproducible echogenic contrast, significantly amplifies Doppler signal and is well tolerated. SHU-454 is injected through the cervix into the uterus and fallopian tubes using the same technique as for radiologic hysterosalpingography. This examination is easily performed in 5 to 10 minutes. Results, compared with two conventional methods, hysterosalpingography and chromolaparoscopy, in 115 women show that HyCoSy is a reliable procedure for detecting tubal patency. HyCoSy results totally agree with the results from the conventional methods in case of tubal patency. This technique may be suitable as an easy, quick and low-risk outpatient examination. It does not involve radiation exposure and is unlikely to cause allergic reactions such as those known to occur with iodinated contrast media. Transvaginal HyCoSy can be used to assess tubal patency early in sterility diagnostics, before adnexal or uterine (myoma) surgery or when tubes and uterine appendages cannot be seen during chromolaparoscopy.

Contrast Media↗

[Color Doppler hysterosalpingography. Preliminary experience].

Tubal factor accounts for approximately 25% of the causes of infertility. The diagnosis has been made with x ray hysterosalpingography or laparoscopy chromoperfusion. We presents the utilization of ultrasonographic color Doppler flow used to perform hysterosalpingography to asses tubal patency.

Constriction, Pathologic↗

[The significance of hysterosalpingography in discovery of oviductal factors in primary infertility].

The hysterosalpingography was performed with 191 women with primary sterility. Pathologic transformations in oviducts were found among the 46 (45.5%) women besides pathology of the uterus which concerned 16 (15.9%) women. Impatency of uterine tube (the right oviduct--13.0%, the left--12.9%) and peritubal adhesions (9.0% on the right side and 12.9% on the left) were the most frequent changes. Hysterosalpingography is a precious diagnostic method in primary sterility and it should be perform comparatively early in the quality of screening examination. A pathology which was affirmed or suspicion of the pathology should be next diagnose with the most invasive methods.

Adult↗

Postoperative hysterosalpingography. Radiographic appearances and clinical results following tubal surgery.

Medical records and postoperative hysterosalpingograms on 23 women following tubal surgery who failed to become pregnant within 2-28 months were reviewed. A total of 39 tubes were analyzed. The surgical indications were reversal of tubal ligation in 24 tubes and correction of tubal or perifimbrial disease in 15 tubes. Tubal ligation had been performed by a variety of methods. At surgery, tubal patency, as shown by chromotubation, was seen in 37 (95%) of 39 tubes. On postoperative hysterosalpingography, tubal spillage was present in 32 (82%) of 39 tubes. Radiographically, the tubes that spilled appeared normal except for occasional shortening after reversal of tubal ligation. The eventual pregnancy rate was 8 (35%) of 23 patients, with 7 intrauterine. Pregnancy occurred only in women under 35 years and was more likely in the group having reversal of tubal ligation. We conclude that among patients who do not initially become pregnant following tubal surgery for infertility, tubal patency is restored in most. During hysterosalpingography, tubes operated on may appear normal or shortened. On long-term follow-up, younger patients and those requiring tubal anastomosis only had a higher pregnancy rate.

Adult↗

[Indications for tubal recanalisation in diagnostic and interventional hysterosalpingography].

Three hundred and seventy-seven hysterosalpingographies performed in 1992 in the Radiology Department of the S. Anna Hospital, Turin, Italy, were reviewed to assess the role and the real incidence of indications to catheterization and to selective salpingography. Proximal tube obstruction treatable by means of extemporary mono-bilateral catheterization was found in 18.3% of cases, but only in 7.4% was catheterization really indicated. In 67.2% of patients repeated contrast medium injections, at high pressure, with the catheter end in front of the internal ostium of the Fallopian tube, allowed recanalization--which made catheterization unnecessary. Catheterization was performed in 18 cases where double injection had failed and was successful in 15 patients (83.3%). Even though selective interventional salpingography is valuable, its use in rarely necessary, especially if conventional hysterosalpingography is performed at the correct injection pressure. Therefore, we conclude that the interventional kit for proximal tube recanalization must always be available, but its use in routine exams is unnecessary.

Adult↗

[Ultrasonographic hysterosalpingography].

The objective of the investigation was to compare US hysterosalpingography with methods currently used to examine tubal patency, i.e. hysterosalpingography and laparoscopy with chromoperturbation. The examination was made in 39 women with the diagnosis of primary or secondary sterility. Consistent with data in the literature, the authors proved a high concordance (86.8%) with reference methods. US HSG is an ambulatory minimally-invasive method of examination of the uterine cavity and patency of the oviducts, which is well tolerated by patients.

Adult↗