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At least 109 records · Page 6Linked to original sources
PubMed1998

Hearing loss related to ototoxicity in children with cancer.

Children undergoing treatment for cancer often receive agents that put them at risk for ototoxicity. Platinum-based chemotherapy, aminoglycoside antibiotics, loop diuretics, and radiotherapy are all capable of inducing inner ear damage, which may result in significant sensorineural hearing loss. Frequent audiological monitoring is necessary for the early detection of changes in hearing thresholds. Age-appropriate modification of audiological testing is essential to obtain accurate results and provide maximum comfort for pediatric patients. When hearing loss is identified promptly, consideration may be given to treatment modification and/or early intervention with hearing aids and other assistive devices. The consequences of hearing loss differ depending on the developmental stage of the child at the time that hearing loss occurs. Language acquisition may be affected in very young children, whereas educational and psychosocial concerns are paramount for the older child. The pediatric oncology nurse is instrumental in assisting the child and family who are coping with hearing loss related to cancer treatment.

Antineoplastic Agents↗
PubMed1988

Vertigo in the pediatric and adolescent age group.

Since episodic vertigo in the pediatric and adolescent age group is unusual and therefore not well known to most otolaryngologists, we present six cases to show some of the various presentations and different underlying causes. These cases covered a wide diagnostic spectrum: meningioma, medulloblastoma, childhood migraine with vestibular symptoms, childhood Meniere's syndrome (one case due to perilymph fistula), and benign paroxysmal vertigo of childhood. The two patients with tumor and the patient with perilymph fistula were treated surgically; the other patients are being managed conservatively since these childhood conditions usually tend to diminish with time.

Adolescent↗
PubMed1996

[Clinical study of time-shift evoked potentials].

Changing the interaural time difference (ITD) of continuous band noise applied to both ears causes a shift in the perceived lateralization of the noise and evokes the special potentials called "time-shift evoked potentials (TPEPs)". These potentials consist of a positive-negative-positive complex, like a slow vertical response (SVR). Each peak latency of this potential, however, was about 20 msec longer than in the SVR. Testing of 45 volunteers with normal hearing revealed that the feature of this response matched the hearing function test results of detecting lateral position of a sound image. Therefore it could be useful as an objective testing for the hearing function of sound latelization. The following were established as the conditions for use, in clinical practice: time difference between ears: 0.7 msec; sound intensity: 30 dB SL at 500-Hz band noise; stimulus interval: 3.0 sec.; and potential recording from Cz on the scalp. This response was tested in 29 cases of hearing disorders (14 cases of inner ear deafness, 2 cases of tinnitus without deafness, 6 cases of peripheral vertigo, 5 cases of intracranial disease, 1 case of functional hearing loss, 1 case of head trauma), and the results were compared with those of the directional hearing test, auditory brainstem response (ABR), and SVR, by using the chi-square test. The results of the directional hearing test and ABR were shown to be correlated with this ERP, and SVR was shown to be independent of it. Thus, it was concluded that this potential is useful as a clinical test. The significance of the conclusions is explained on the basis of Berjeik's theory.

Evoked Potentials, Auditory↗
PubMed1999

[Objective audiologic assessment of children treated with amikacin].

Hearing assessment of 14 children suffered from urinary tract infection and treated by amikacin is reported. The dosage of amikacin was 7.5 mg/kg/daily for 10 days and the serum level of amikacin not exceeded the 35 mcg/ml. The aim of the study was on the one hand to determine the hearing damaging side effect of amikacin and on the other to assess the usefulness of objective methods for detection of hearing loss in this population. Authors used for screening a transient otoacoustic emission (TEOAE) during and after (2-4 weeks) therapy. If subjective and objective (TEOAE) methods gave a good result, no further checkup has considered as necessary, but if there were no evoked emission, acoustic brainstem response audiometry has been carried out for verification. It result no hearing loss could be detected in the measured specimen. In conclusion it has been stated that by proper dosage and serum level screening amikacin may no lead to hearing loss in children, and objective methods are valuable for hearing screening and monitoring of such population of children.

Adolescent↗
PubMed1988

Limitations of ABR as a hearing test as exemplified in multiply handicapped adults.

Some limitations of the audiometric application of the click-evoked ABR are exemplified in the results for this sample of multiply handicapped hearing-impaired adults. Normal ABR thresholds were not necessarily indicative of normal hearing. Complete absence of ABR was not necessarily associated with total deafness. These findings underscore the need for conservative interpretation when the ABR is used to assess hearing of neurologically impaired patients at risk for more central auditory dysfunction. Additional diagnostic information in problematic cases may be obtained with cortical auditory potentials. Electrophysiological data must, in turn, be integrated with behaviorally obtained results.

Adult↗
PubMed1979

Detecting non-valid hearing tests in industry.

As greater numbers of workers come under industrial hearing conservation programs, the problem of nonorganic hearing loss is become critical. The potential malingerer can be identified by behavioral observations both before and during the testing of hearing and by an analysis of test results. Manual, self-recording, and microprocessor audiometry all incorporate validity and reliability checks which assist in detecting the malingerer. Methods of documenting inaccurate hearing tests are detailed, along with ways of obtaining accurate follow-up tests. The key to alleviating the problem of malingering is early detection and immediate resolution of the problem.

Audiometry↗
PubMed1982

[Vitamin A concentration in plasma and ability to hear in patients with chronic alcoholic liver diseases].

59 patients with chronic alcoholic liver disease and with negative history of ear infection, noise exposure, head injury, use of streptomycin and without hereditary deafness underwent a basic audiologic examination. In all age groups we found a depression of the pure tone threshold on from 2,000 Hz and compared to a control group and to the norm curves (Spoor 1966). Following the Carhart-test and the acoustic facial reflex there were always signs of cochlear lesions. Fifty per cent of the alcoholics in the Carhart tone decay test showed a depression of the threshold between 10 and 30 dB. The concentration of vitamin A, RBP, beta-Carotin and zinc in the blood measured at the same time were diminished. Considering recent electron microscopic findings on the pattern of the inner ear of young rats following vitamin A deficit we suppose that the vitamin A deficit in the alcoholics leads to poor hearing.

Adult↗