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At least 109 records · Page 6Linked to original sources

Lensectomy for complicated cataract in juvenile chronic iridocyclitis.

Experience with the removal of complicated cataract by lensectomy in patients with juvenile chronic iridocyclitis (JCI) has so far been limited. The results of lensectomy were reviewed retrospectively in 131 patients with JCI (187 eyes). The mean follow up period was 5 years 4 months. The main operative complication was accidental loss of lens material into the vitreous cavity. The postoperative complications were glaucoma (23 eyes, 15%), phthisis (14 eyes, 8%), secondary pupillary membranes (11 eyes, 6%), and retinal detachment (six eyes, 3%). The incidence of postoperative phthisis was related to the level of intraocular pressure (IOP) at the time of surgery. Twenty four per cent of hypotonous eyes and 4% of eyes with normal or elevated IOP became phthisical. Visual acuity was improved in 77%, was worse in 13%, and unchanged in 10% of eyes. The main causes of a postoperative visual acuity of 6/60 or less were glaucoma, amblyopia, and phthisis. Lensectomy did not appear to alter the course of uveitis.

Adolescent↗

Cataract surgery in Fuchs' heterochromic iridocyclitis.

Eighteen eyes in 17 patients with Fuchs' heterochromic iridocyclitis underwent cataract extraction with or without intraocular lens implantation (17 extracapsular and one intracapsular). Intraoperative complications included hyphaema, poor pupillary dilatations, and localised zonule dehiscence with vitreous loss. Only four eyes developed a marked anterior uveitus (two pseudophakic and two aphakic) which resolved within 2 weeks with topical steroids. Three eyes developed a rise in intraocular pressure (IOP) to more than 30 mm Hg on the first postoperative day. In all three eyes the IOP returned to normal off all therapy within 1 week. In one of three eyes preoperative glaucoma was made worse following surgery. Visual acuity testing revealed that 15 eyes (83.3%) achieved 6/12 vision or better. Lamellar macular hole, pre-existing macular scar, and pre-existing retinal detachment accounted for the poor visual result.

Adult↗

Reduction of macular oedema by acetazolamide in patients with chronic iridocyclitis: a randomised prospective crossover study.

Thirty patients with cystoid macular oedema secondary to chronic iridocyclitis were enrolled in a two period, prospective, randomised, double masked, crossover study that compared sustained release acetazolamide (500 mg twice a day) with a placebo to measure the effects on the reduction of cystoid macular oedema and improvement of visual acuity. All patients were treated for 1 month with either acetazolamide or placebo, received no treatment for 1 month, and were then treated for 1 month with the other medication. Statistically significant improvement in visual acuity was seen at 14 and 28 days in the treated patients. No improvement was seen when patients received placebo. Improved visual acuity was not associated with race or sex. However, younger patients (under age 55 years) were more likely to benefit from treatment. Results of vitreous fluorophotometry, obtained at baseline and 4 weeks, demonstrated an improvement in posterior vitreous penetration ratios and mid vitreous penetration ratios after treatment with acetazolamide but not with placebo.

Acetazolamide↗

Risk factors for herpes simplex virus epithelial keratitis recurring during treatment of stromal keratitis or iridocyclitis. Herpetic Eye Disease Study Group.

AIMS: Possible risk factors were evaluated for herpes simplex virus (HSV) epithelial keratitis in patients with stromal keratouveitis. METHODS: The study population included 260 patients who had active stromal keratitis and/or iridocyclitis without epithelial disease and who were enrolled in one of three clinical trials of the Herpetic Eye Disease Study. Study treatment involved a 10 week course of topical placebo, topical prednisolone phosphate, or topical prednisolone phosphate with oral acyclovir. All groups received topical trifluridine four times daily for 3 weeks then twice daily for another 7 weeks. Patients were examined for HSV epithelial keratitis for 16 weeks. RESULTS: Dendritic or geographic epithelial keratitis occurred in 12 (4.6%) study patients. Adverse effects attributable to trifluridine prophylaxis were acute allergic blepharoconjunctivitis in 10 (3.8%) study patients and corneal epithelial erosions in 11 (4.2%) study patients. No significant difference in the occurrence of HSV epithelial keratitis was found among the study treatment groups: one (2.0%) of 49 topical placebo treated patients, nine (6.5%) of 138 patients treated with topical corticosteroids without acyclovir, and two (2.7%) of 73 patients treated with topical corticosteroids and oral acyclovir. Univariate exponential models suggested that patients with a history of previous HSV epithelial keratitis and non-white patients were more likely to develop HSV epithelial keratitis during treatment of stromal keratouveitis. CONCLUSION: Individuals with prior HSV epithelial keratitis and certain ethnic groups may have a higher rate of recurrent epithelial keratitis during the acute treatment of HSV stromal keratouveitis.

Acyclovir↗

Recurrent subconjunctival hemorrhages in patients with Fuchs' heterochromic iridocyclitis.

We examined two women who had keratic precipitates, minimal intracameral cells and flare, diffuse iris stromal atrophy, posterior subcapsular cataract, and vitreous opacities in their left eyes. No ocular pain, photophobia, or posterior synechia was noted. Their right irises appeared brown. Heterochromia was evident in both patients. Recurrent subconjunctival hemorrhages were also in their affected left eyes. It is possible that subconjunctival hemorrhages in our patients may be associated with Fuchs' heterochromic iridocyclitis.

Atrophy↗

Isolation of Leishmania sp. from aqueous humor of a patient with cutaneous disseminated leishmaniasis and bilateral iridocyclitis (preliminary report).

The authors report an uncommon case of leishmaniasis with disseminated cutaneous lesions, systemic manifestations and ocular involvement, the latter being characterized by bilateral nongranulomatous iridocyclitis. The severity of the ophthalmologic lesions and its unresponsiveness to therapy (in spite of satisfactory regression of both systemic and cutaneous manifestations) lead to a needle aspiration of the anterior eye chamber content. From this material Leishmania sp was isolated. To our knowledge this is the first time that Leishmania has been shown into the ocular globe.

Amphotericin B↗

[The preclinical diagnosis, prevention and treatment of postoperative iridocyclitis in patients after intraocular aphakia correction].

Three hundred and fifty-two patients with senile cataract were followed up. Herpes-virus and Chlamydia infections were proven to be important in the development of exudative complications as observed during the early postoperative period in patients after cataract extraction and IOL implantation. The phagocyte index as well as the phagocyte number were found to be reliably reduced versus the normal values in patients with postoperative iridocyclitis.

Acridines↗

Syphilitic gummatous iridocyclitis.

We present a rare case of gummatous syphilitic iridocyclitis. The differential diagnosis, clinical characteristics, and treatment of this ocular disease are discussed.

Adult↗

Reactivation in children of juvenile chronic arthritis and chronic iridocyclitis associated with human herpesvirus-6 infection.

The human herpesvirus-6 (HHV-6) causes exanthem subitum. Moreover it can provoke a large scale of different other clinical symptoms. The life-long persistence of human herpes viruses is well known (HSV 1 and 2, VZV, CMV, EBV). For the HHV-6 we have described here for the first time the onset/reactivation of juvenile chronic arthritis (jcA) and chronic iridocyclitis as chronically active and persistent infection in two children of school age.

Antibodies, Viral↗

[Chronic tuberculous iridocyclitis].

One patient is seventy-one years old, diagnosed four years ago with latero-cervical ganglionic tuberculosis, presents approximately one year and half, progressive loss of the vision in both eyes, predominant in the left-eye; for several months periocular pains referred to the left hemicranial field are presented. Ocular exam: visual acuity was 1/100 in the right eye and perception movements of the hand in the left eye: intraocular pressure was 28 mmHg in the right eye and 8 mmHg in the left eye: perikeratic congestion, chemosis, pigmented precipitates on the posterior face of the corneo, iris in "umbrella", seclusion and occlusion of the pupillary at the left eye, posterior synechiae at the right eye were noted. The eye ground exam is not possible due the pupillary partial seclusion at the right eye and the pupillary seclusion-occlusion at the left eye. The general exam releaves several latero-cervical keloid scars and pronounced dysphonia. Laboratory exam: IDR of the tuberculin was high positive, chest radiography shows hilar bilateral calcifications, ORL exam shows a tumor at the foot of the epiglottis and anatomopathological exam shows low differentiated epidermoid carcinoma. Using the anamnestic dates, clinical and paraclinical exams, we established the diagnosis: chronic tuberculosis iridocyclitis with pupillary seclusion and occlusion at the both eyes; secondary glaucoma at the right eye: latero-cervical ganglionic tuberculosis: epidermoid laryngeal carcinoma.

Aged↗

[A case of relapsing iridocyclitis in tropical malaria].

An African student developed bilateral relapsing iridocyclitis with increased intraocular pressure. General examinations and parasitological studies revealed tropical malaria. Etiotropic and local therapy normalized intraocular pressure and improved vision acuity of both eyes. This case should be borne in mind by general practitioners as a possibility of transportation of various tropical diseases.

Antimalarials↗

Bilateral iridocyclitis caused by Mycobacterium leprae diagnosed through paracentesis.

The authors conducted an anterior chamber paracentesis in a patient with lepromatous leprosy showing bilateral iridocyclitis. The paracentesis was performed in the outpatients department. The aqueous humor was studied by Ziehl-Nielsen staining method and the result was the isolation of the M. leprae in the anterior chamber. This study shows that M. leprae can promote uveitis in leprosy patients. Therefore, it should be looked for in patients having this type of disease.

Aged↗

Fuchs' heterochromic iridocyclitis in blacks.

Fuchs' heterochromic iridocyclitis (FHI) is a frequently overlooked cause of anterior uveitis. Improper diagnosis may lead to unnecessary therapy. Dark brown irides may demonstrate heterochromia poorly. We believe that FHI may be overlooked in blacks because of a frequent lack of obvious heterochromia and the frequent presence of iris nodules. Heterochromia is not necessary for the diagnosis of FHI if other clinical features of the syndrome are present. In our series of 54 whites and 13 blacks with FHI, heterochromia occurred in 50 (92%) whites and ten (76%) blacks (nonsignificant difference). Iris nodules occurred in 11 (20%) whites and four (30%) blacks (not significant). Statistically significant differences occurred with cataract/aphakia in 41 (75%) whites and three (23%) blacks and with glaucoma in six (11%) whites and five (38%) blacks.

Age Factors↗

Cytomegalovirus in juvenile iridocyclitis.

We cultured cytomegalovirus from lens material aspirated from the eye of a 4-year-old boy who had a severe bilateral iridocyclitis and secondary cataracts. There were neither systemic manifestations of congenital disease nor chorioretinitis.

Child, Preschool↗

Extracapsular cataract extraction in Fuchs' heterochromic iridocyclitis.

We studied 15 patients with Fuchs' heterochromic iridocyclitis who underwent extracapsular cataract extraction. Ten patients also had capsular-fixated posterior chamber intraocular lens implantation. The patients were followed up for a mean of 23 months (range, six to 48 months). The clinical course and visual outcome were favorable. All patients had a postoperative best-corrected visual acuity of 20/40 or better. There were no major surgical, intraoperative, or postoperative complications.

Adult↗

Retinal arteritis, iridocyclitis, and giardiasis.

The intestinal parasite Giardia lamblia was found in the stools of three patients with retinal arteritis. Iridocyclitis was also present in two of these patients, who had not responded to treatment with systemic corticosteroids. Antiparasitic drug treatment was followed by improvement of ocular and systemic findings.

Adult↗

Traumatic hyphema and iridocyclitis in the horse.

Traumatic iridocyclitis and hyphema in the horse usually follow blunt blows to the orbit and eye. The condition is characterized by miosis, ocular hypotony, ciliary flush, swelling of the iris, and hemorrhage with excessive fibrin in the anterior chamber which permits from 2 to 6 weeks. Vigorous treatment with mydriatics, topical and systemic corticosteroids is recommended. Possible complications include anterior and posterior synechiae, cataracts, and fibropupillary membranes.

Animals↗