SEARCH · PubMed Health

Results for “Laser Coagulation”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources

PubMed1982

Temperature behaviour of a model port-wine stain during argon laser coagulation.

Temperature calculations on a model of a port-wine stain during argon laser coagulation have been performed. The model consists of four plane parallel layers representing the epidermis, the upper dermis, the superficial capillary blood plexus, and the deeper dermis. The light distribution inside the skin is calculated on the basis of the Kubelka-Munk theory. The numerical calculations have been performed by an 'alternating-direction-implicit' finite difference method. For the usual combination of exposure time and beam radius of the argon laser (between 0.1 and 0.6 s, and 0.5 mm or 1 mm) the shortest exposure time and largest beam radius yields the most efficient plexus coagulation. The model confirms that plexus coagulation implies destruction of epidermis and stratum papillare. Heat summation effects at the laser spot boundaries can be avoided when a distance of 2.5 times the beam radius is used between adjacent spots (centre-to-centre). An optimal argon laser treatment technique is suggested yielding full plexus coagulation with minimal or no scarring. Two simple physical requirements are given for the ideal laser to coagulate port-wine stains in an efficient and selective manner, suggesting application of pulsed dye lasers, emitting either at 418 nm or at 577 nm.

Hemangioma↗

PubMed1995

Interstitial laser coagulation for benign prostatic hyperplasia: preliminary clinical results.

We report our early experience in the clinical application of interstitial laser coagulation of the prostate (ILCP) in the treatment of benign prostatic hyperplasia (BPH). Neodymium: YAG laser energy is transmitted via a specially designed interstitial thermotherapy light-guide. The light guides were inserted transurethrally into each lobe of the prostate by direct puncture, under direct visualization. The prostatic urethra is preserved during the procedure. From December 1993 to March 1994, 37 patients with symptomatic BPH were treated with ILCP. Treatment outcome was evaluated by the International Prostatic Symptom Score (I-PSS), flow rate, postvoided residual urine volume and quality of life score. Significant improvement in I-PSS and peak flow rate was observed at 3 months: I-PSS decreased from a mean of 19.3 to 10.4, and the peak flow rate increased from a mean of 7.2 to 9.4 ml/sec (p < 0.0001). The mean postvoided residual urine volume significantly decreased from 91 to 47 ml (p < 0.01). Two days after ILCP the serum prostate-specific antigen had increased by 860%, evidence of the significant tissue damage produced by laser irradiation. The quality of life score significantly decreased from a mean of 4.8 to 2.1 (p < 0.0001). No serious side-effects were observed. The early clinical results suggest that ILCP is safe and effective as a treatment of BPH and is less invasive than some other methods.

Aged↗

PubMed2006

Synergistic effect of interstitial laser coagulation and doxorubicin in a murine tumor recurrence model of solitary colorectal liver metastasis.

BACKGROUND: Interstitial laser coagulation (ILC) is gaining acceptance for treatment of unresectable colorectal liver metastases. However, local recurrence rates are still high. To overcome this problem, we investigated the potential of additional systemic therapy after ILC in a murine model. METHODS: Single C26 colon carcinoma nodules (approximately 1 mm3) expressing firefly luciferase were implanted in the left liver lobe of 32 BALB/c mice. Seven days after implantation, tumors were treated with either ILC alone (neodymium-yttrium aluminum garnet; 6 W/cm; 800 J/cm) or ILC followed by 1 mg/kg of doxorubicin intravenously. Controls received either doxorubicin alone or sham treatment. Tumor load was measured by in vivo bioluminescent imaging. RESULTS: Solitary colorectal liver metastases developed over 7 days after tumor implantation in the liver. Extrahepatic disease was not observed. The ILC dose was set to ablate the liver metastases with recurrent tumor growth in 9 of 16 mice after 7 days. After ILC plus doxorubicin, complete tumor destruction occurred without recurrence (0 of 14). Sham treatment or treatment with doxorubicin alone showed an exponential increase in tumor load. CONCLUSIONS: A murine tumor recurrence model after local ablative treatment of solitary liver metastasis was developed. The combination of ILC and doxorubicin had a strong synergistic effect that led to complete tumor remission in all animals treated.

Animals↗

PubMed2003

Interstitial laser coagulation versus transurethral resection of the prostate for benign prostatic enlargement--a prospective randomized study.

OBJECTIVE: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). MATERIAL AND METHODS: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomatic BPE were included in the study. Seven were subsequently excluded due to intercurrent disease or protocol violation and the remaining 31 were randomized to either TURP (n=11) or ILC (n=20). A suprapubic tube was inserted in all ILC-treated patients, and ILC was performed as an outpatient procedure when feasible. Data were recorded preoperatively and at 3-month and 1-year follow-up. The assessment parameters were International Prostate Symptom Score (IPSS), uroflow, prostate volume determined by means of transrectal ultrasound and postvoid residue. RESULTS: At 1-year follow-up, uroflowmetry indicated a more pronounced increase in peak urinary flow rate (Qmax) in the TURP patients than in the ILC subjects (p<0.02). Differences in postvoid residue, IPSS and prostate volume between the two treatments could not be evaluated due to the small number of patients in each group. Postoperative urinary tract infections occurred in 13 ILC patients but in only one TURP subject, and catheterization was done for 24 days after ILC and for 2 days after TURP. The study was ended prematurely due to the prolonged postoperative catheterization and the high rate of urinary tract infections in the ILC patients. CONCLUSIONS: At 1-year follow-up, the increase in Qmax was smaller in the ILC subjects than in the TURP patients. The ILC subjects had comparatively more postoperative urinary tract infections and more prolonged postoperative catheterization than the TURP patients.

Aged↗

PubMed1997

Influence of laser coagulation therapy on untreated fellow-eyes in severe nonproliferative diabetic retinopathy-spectrometric results.

PURPOSE: The aim was to examine the influence of laser treatment on untreated fellow-eyes. METHODS: The effectiveness of the laser photocoagulation was investigated in 24 patients with type II diabetes mellitus and severe nonproliferative diabetic retinopathy. Using a spectrometric technique, the measurements in the macula were performed one day before laser coagulation and on the day directly following laser treatment. Further investigations took place 14 days and 6 weeks later. RESULTS: One day after coagulation, the reflection of the untreated fellow-eyes was found to be significantly increased between 530 and 600 nm, compared to the same eyes before coagulation. However, 14 days and 6 weeks after laser treatment alterations in the untreated eyes were no longer detectable. CONCLUSION: The choroidal blood volume seems to be decreased not only in coagulated eyes, but also in untreated fellow-eyes, and, presumedly, the choroidal blood flow is improved. Considering the short duration of these effects, a therapeutic consequence is not supposed.

Adult↗

PubMed1999

Long-term effects of interstitial laser coagulation in porcine liver with portal inflow occlusion: central versus peripheral lesions.

PURPOSE: Interstitial laser coagulation (ILC) is an attractive modality for local destruction of unresectable hepatic metastases. Portal inflow occlusion considerably increases its destructive capacity, resulting in lesions 5 cm in diameter; however, effects on adjoining major intrahepatic structures are unknown. Therefore, the purpose of this study was to assess the effects of ILC with portal inflow occlusion on the central portion of the liver as compared to the peripheral portions. MATERIALS AND METHODS: ILC was performed in pigs with portal inflow occlusion. Each animal received a single laser application with Nd:YAG light guided simultaneously through four interstitial fibers with 5 W per fiber during 6 minutes. Location of treatment was randomized to either central (n = 8) or peripheral (n = 8). Follow-up was for 1, 2, or 3 months with evaluation of liver functions and weight, as well as macroscopic and microscopic assessment of coagulated lesions and surrounding parenchyma. RESULTS: There was no treatment-related morbidity or mortality. No obstructive cholestasis or bile leakage was found. At every moment of evaluation, coagulated volumes in the central group were smaller than in the peripheral lesions (P = .03). Large vessels contiguous to the lesions in the central group were always intact and indications of portal hypertension or thrombosis of hepatic veins were not found. There were no significant differences between the two groups (liver functions [P > or = .15] and weight [P = .69]). CONCLUSION: ILC with portal inflow occlusion is a safe technique in the vicinity of vital structures in the liver of healthy pigs. These results justify studies to the feasibility and complication rate of portal inflow occlusion in patients with hepatic malignancies.

Animals↗

PubMed1996

[Visual laser coagulation for benign prostatic hyperplasia. Preliminary experiences].

A total of 28 patients with symptomatic bladder outlet obstruction due to benign prostatic hyperplasia were treated by visual laser coagulation (VLAP) performed with the Myriadlase sidefiring neodymium: YAG laser fibre at 40 Watts power. The treatment was performed as an outpatient procedure using intraurethral gel anaesthesia and light intravenous sedation and analgesia. Prostatic volume was 32 g (18-90 g), and 650 Joule per gram prostatic tissue (516-1000 J/g) was administered. The patients were evaluated at mean 9.2 weeks. The mean operative time was 34 minutes. The procedure was very gentle, all patients tolerated it well and there was no bleeding. Most patients experienced some dysuria for three to four weeks after the procedure, two had severe symptoms. Two patients remained in retention and required transurethral resection. The rest expressed subjective satisfaction with the results. Peak urinary flow increased from mean 9.0 ml/sec preoperatively to 15.4 ml/sec; a mean increase of 78%. One patient developed clinical urinary tract infection. There were no other complications of clinical significance.

Aged↗

PubMed1996

[Results of pan-retinal argon laser coagulation in proliferative diabetic retinopathy].

To minimize the risk of visual loss and to stop the progression of diabetic retinopathy argon laser treatment is the therapy of choice in proliferative diabetic retinopathy (PDR). The results after panretinal argon laser coagulation (ALC) were studied retrospectively considering visual outcome and frequencies of diabetic ocular complications. In all 95 patients were included in whom laser treatment had been performed due to clinically and angiographically diagnosed proliferative diabetic retinopathy at the Department of Ophthalmology between 1990 and 1994 with a follow-up of at least 1 year. The most frequent diabetic complications observed were vitreous haemorrhage in 9 (or 9.5%) and iris neovascularization in 10 cases (or 10.5%). Rare complications were neovascular glaucoma in 3 patients (or 3.2%) and tractional retinal detachment in 4 patients (or 4.2%). Nearly 70% of the patients maintained or improved visual acuity after laser treatment. The frequency of diabetic complications of PDR after ALC was significantly associated with older age, diabetes type II, longer duration of diabetes and elevated blood pressure.

Adult↗

PubMed1993

Panretinal photocoagulation in diabetic retinopathy: argon versus dye laser coagulation.

The range of wavelengths used in ophthalmic photocoagulation treatment has been greatly enlarged by the development of the dye laser. To investigate the efficacy and possible side effects of orange dye laser light in the treatment of diabetic retinopathy, we performed a prospective, controlled clinical study comparing argon blue-green and orange dye laser light. In 14 patients with diabetic retinopathy of equal severity in both eyes one eye was randomly assigned to either blue-green argon (488 and 514.5 nm) or orange dye (600 nm) panretinal laser treatment. The total coagulated area was the same in both eyes. Subjective parameters (visual acuity, perimetry, color vision) as well as objective functions (electroretinography, electro-oculography) and the clinical course were studied preoperatively and then postoperatively over a period of 6 months. Dye laser coagulation proved as effective and safe as blue-green argon laser coagulation in the panretinal treatment of diabetic retinopathy. No significant differences in postoperative retinal function were detected. However, orange laser coagulation proved significantly more painful than blue-green argon laser treatment (P = 0.002).

Adult↗

PubMed2002

Laparoscopic interstitial laser coagulation of renal tissue with and without hilar occlusion in the porcine model.

PURPOSE: To evaluate the safety and efficacy of interstitial laser coagulation (ILC), applied via a laparoscopic approach, with and without hilar occlusion in the porcine model. MATERIALS AND METHODS: In nine female farm pigs, bilateral renal mobilization was performed via a transperitoneal laparoscopic approach. Using a 600- micro m bare-tip silicon diode laser fiber inserted 0.5 cm into the lower pole of each kidney, diode laser energy (wavelength 805 nm) was applied for 15 minutes at 6 W. In each pig, the left renal hilum was clamped during ILC. Animals were sacrificed immediately (N = 3) or at 2 weeks (N = 3) or 4 weeks (N = 3). The kidneys were inspected grossly, and the lesions were evaluated microscopically. Nicotinamide adenine dinucleotide (NADH) histochemical staining was performed to assess viability. RESULTS: Grossly, parenchymal lesions appeared firm and white with a central zone of carbonization, cavitation, or both. Histopathology examination revealed cellular inflammation in acute lesions; chronic lesions demonstrated coagulative necrosis with progressive fibrosis. The NADH staining showed residual viable cells within the treatment zone of survival animals but not in acute animals. The mean size of the treatment zone in kidneys with unoccluded blood flow was 2.4 x 2.1 x 2.0 cm, 4.0 x 3.3 x 2.8 cm, and 3.3 x 3.5 x 2.0 cm in the acute, 2-week, and 4-week group, respectively. Hilar occlusion resulted in a slightly, but statistically insignificantly, larger lesion. In the 2-week survival group, one animal had a left subcapsular hematoma on the hilar-occluded side. In another 2-week animal, extension of the ILC zone was noted beyond the kidney into the psoas muscle. In the 4-week survival group, two animals developed gross hematuria; one had a left perinephric urinoma and urine leak noted at necropsy. CONCLUSIONS: Renal ILC may represent an alternative minimally invasive technique for ablation of renal tumors. However, histologic evidence of viable cells within the treatment zone mandates refinement of the technique in the animal model before further application in humans. Hilar occlusion does not appear to enhance tissue ablation.

Animals↗

PubMed1997

Heat-resistant cylindrical diffuser for interstitial laser coagulation: comparison with the bare-tip fiber in a porcine liver model.

BACKGROUND AND OBJECTIVE: Interstitial laser coagulation is an experimental treatment to eliminate solid tumors such as hepatic metastases. The pattern of light emission from the fiber tip is probably an important factor in determining the size and shape of a lesion. A heat-resistant cylindrical light diffusing tip of 2 cm length was developed for this application. We performed an in vitro study to compare this diffusing-tip with a bare-tip fiber. STUDY DESIGN/MATERIALS AND METHODS: Fiber ends were positioned between two porcine liver slabs (37 degrees C) and Nd:YAG laser light (1064 nm) was guided through either fiber with an output of 3-9 W and exposure times of 6-18 minutes. RESULTS: Lesions produced by the cylindrical diffuser tip were significantly larger and more predictable. With the diffuser tip, lesions up to 36/23 mm (length/width) could be produced at 7 W and 9 min without any central charring. The maximum size of lesions produced with the bare-tip fiber was 32/20 mm at 6 W for 9 min with massive charring. CONCLUSIONS: The results indicate that at optimal laser settings, the diffuser tip produces a larger coagulation volume than a bare-tip fiber. For clinical application, cylindrical diffusing fibers should be used with a diffusing length adapted to the diameter of the tumor.

Animals↗

PubMed1999

Interstitial laser coagulation and transurethral needle ablation in the management of lower urinary tract symptoms due to benign prostatic obstruction.

Interstitial laser coagulation and transurethral needle ablation, two different techniques for heat-treatment of symptomatic benign prostatic hyperplasia, are outlined. Both treatments have been performed in sedoanalgesia. The results of this research and data from the literature show that both treatment modalities have a marked effect on symptoms. Objective parameters, such as uroflow, are moderately changed postoperatively. The side-effect profiles appear favourable, especially with respect to bleeding per- and post-operatively. However, further long-term data is required.

Catheter Ablation↗

PubMed1976

[Clinical results of laser-coagulation in gastro-intestinal bleeding (author's transl)].

Endoscopic laser-coagulation was used 94 times in 14 patients to stop gastro-intestinal bleeding or coagulate potential bleeding sources during non-bleeding intervals. Lasting haemostasis was achieved in three cases of incomplete gastric erosion, one of gastric ulcer, one of duodenal ulcer and one of bleeding after antral rugectomy. It failed to stop severe arterial bleeding in a case of gastric carcinoma. Lasting haemostasis was achieved in six haemangiomas of the colon, one case of angiomatosis of the antrum with 62 individual sites, two of angiodysplasia of the colon, 17 lesions in Osler's disease of the oesophagus (2 cases), stomach (10) and duodenum (5). The procedure was performed in the course of diagnostic endoscopy with an argonion laser developed by the authors, which has a density of 0.7-1.3 W/mm2. No complications have been observed so far.

Argon↗

PubMed2003

Combination of interstitial laser coagulation and transurethral resection of the prostate: ex vivo evaluations.

OBJECTIVES: To evaluate the combination of interstitial laser coagulation (ILC) and transurethral resection of the prostate (TURP) in an ex vivo model. Perioperative bleeding is still regarded as the main complication of conventional TURP. The minimally invasive procedure ILC and the highly effective TURP seem to be a promising concept to improve hemostasis. METHODS: Isolated blood-perfused porcine kidneys were used to determine hemostatic efficacy of different interstitial laser procedures (neodymium:yttrium-aluminum-garnet [Nd:YAG], 1064 nm; and holmium:YAG [Ho:YAG], 2100 nm) in combination with conventional TURP. Bleeding could thus be quantified in relation to tissue ablation for the different techniques. Additionally, the specimens were evaluated histologically. RESULTS: A combination of Nd:YAG ILC, followed by TURP, resulted in significantly (P <0.001) reduced bleeding compared with TURP alone for a standardized ablation volume of 16 cm(3) of perfused kidney tissue (5.1 mL/min versus 24.1 mL/min). Similarly, significantly (P <0.001) better hemostasis was demonstrated with the combination of Ho:YAG ILC compared with TURP alone (4.8 mL/min versus 24.1 mL/min). The differences between the two laser procedures were not significant. The histologic examinations revealed significantly larger coagulation zones for the groups pretreated with Nd:YAG ILC or Ho:YAG ILC compared with TURP alone. CONCLUSIONS: ILC before conventional TURP leads, ex vivo, to a significantly superior hemostasis compared with TURP alone. The hemostatic effects of Nd:YAG and Ho:YAG laser treatments seem comparable.

Animals↗

PubMed1996

Transurethral interstitial laser coagulation for benign prostatic hyperplasia: treatment outcome and quality of life.

OBJECTIVE: To assess the efficacy and safety of transurethral interstitial laser coagulation (ILC) in the treatment of benign prostatic hyperplasia (BPH). PATIENTS AND METHODS: From December 1993 to March 1995, 61 patients (mean age 69.7 years, range 55-89) with symptomatic BPH were treated with ILC. A neodymium: YAG laser was used in combination with specially designed interstitial thermotherapy light-guides. The tip of the light guide was inserted repeatedly into each lobe of the prostate transurethrally, under direct vision. The number of fibre placements depended on the size and configuration of the gland. The prostatic urethra was preserved during the procedure. Treatment outcome was evaluated using the International Prostatic Symptom Score (IPSS), measurement of urinary flow rate and post-void residual urine volume (PVR). The disease-specific quality of life (QOL) was assessed using a QOL assessment score and a BPH impact index. Independently of the symptom assessment, a self-reporting questionnaire was completed 3 months after treatment to determine the patients' satisfaction with the treatment and their sexual function. RESULTS: Among the 31 patients followed for 6 months, the mean IPSS decreased significantly, from 18.9 at baseline to 7.7 (59% improvement; P < 0.001), the mean peak flow rate increased from 6.7 mL/s to 10.0 mL/s (49% improvement; n = 29; P < 0.001), the mean PVR decreased from 119 mL to 29 mL (76% improvement; n = 28, P < 0.001) and the mean prostate volume decreased significantly, from 37.1 mL to 31.6 mL (15% reduction at 3 months; n = 52, P < 0.001). There was a steady and progressive improvement in both the QOL assessment and the BPH impact index scores at 3 and 6 months. More than 90% of the patients reported satisfaction with the treatment and none reported the new onset of erectile dysfunction. There were no serious side-effects, except for two cases of loss of ejaculation. CONCLUSIONS: The early clinical results suggest that the ILC procedure is a safe and effective less-invasive treatment for BPH that appears to have favourable effects on the patients' quality of life.

Aged↗

PubMed2006

Stage-related outcome in twin-twin transfusion syndrome treated by fetoscopic laser coagulation.

OBJECTIVE: To assess perinatal outcome in monochorionic twin pregnancies according to different stages of severe mid-trimester twin-twin transfusion syndrome managed by fetoscopic laser coagulation of the placental vascular anastomoses. METHODS: In a prospective study fetoscopic laser therapy was performed in 200 consecutive pregnancies with severe mid-trimester twin-twin transfusion syndrome at a median gestational age of 20.7 weeks (range 15.9-25.3 weeks). Outcome data were analyzed for the whole group and separately for each stage according to the Quintero staging system. RESULTS: The overall survival rate was 71.5% (286/400), with survival of both twins in 59.5% (119/200) and survival of at least one of the twins in 83.5% (167/200). The median gestational age at delivery of liveborn neonates was 34.3 weeks (range 23.1-40.4 weeks). There was a significant trend toward reduced survival rates with increasing stage (P=.038). The percentage of pregnancies with survival of both fetuses was 75.9% (22/29) for stage I, 60.5% (49/81) for stage II, 53.8% (43/80) for stage III, and 50% (5/10) for stage IV. At least one of the twins survived in 93.1% (27/29) at stage I, 82.7% (67/81) at stage II, 82.5% (66/80) at stage III, and 70% (7/10) at stage IV. The overall survival rate for donor fetuses was 70.5% (141/200) and for recipient fetuses, 72.5% (145/200). CONCLUSION: These data show that laser therapy is an effective therapeutic option for all stages of severe twin-twin transfusion syndrome and provide information to counsel patients according to the stage of the syndrome.

Arteriovenous Anastomosis↗

PubMed1993

Water-jet-cooled Nd:YAG laser coagulation of experimental liver metastases: correlation between ultrasonography and histology.

To establish the value of ultrasonography in imaging laser coagulation of tumor and surrounding tissue, the relation between measurements on ultrasound and histology was determined in a rat tumor model. A piece of colon carcinoma CC531 was implanted in the liver of 21 Wag/Rij rats; 20 days later, tumors (mean diameter 5.3 mm) were treated with a water-jet-cooled Nd:YAG laser at 10 W and either 150 J, 300 J, 600 J, 1,200 J, 1,700 J, or 2,400 J. Ultrasonography was done just pre- and immediately post-laser treatment. The animals were sacrificed and livers removed for light microscopical evaluation. Depth and width of coagulation were measured directly on ultrasound, and on histological samples by computer-assisted image analysis. Laser treatment did not change the echogenic aspect of the tumor on ultrasound. However, liver damage appeared hypoechoic compared to normal liver. A significant correlation was found between the total size of the lesion on ultrasound and histology (P = 0.015, r = 0.57 for depth; P = 0.012, r = 0.58 for width), suggesting that laser induced tumor destruction may be derived from the amount of surrounding hepatic damage on ultrasound.

Adenocarcinoma↗

PubMed2003

Interstitial laser coagulation of the prostate for management of acute urinary retention.

PURPOSE: We evaluated the clinical efficacy and benefit of interstitial laser coagulation of the prostate (ILCP) in patients with benign prostatic hyperplasia (BPH) presenting with acute urinary retention. MATERIALS AND METHODS: Patients presenting with acute urinary retention were prospectively evaluated. Patients underwent ILCP and outcomes were evaluated by post-void residual urine, maximum flow rate, International Prostate Symptom Score, and disease specific quality of life score at baseline, 1, 3, 6 and 12 months. RESULTS: A total of 85 patients were enrolled in the study and 53 were diagnosed with acute urinary retention secondary to BPH. A total of 33 were not catheter-free after a week and 28 of them agreed to undergo ILCP. Mean preoperative prostate volume was 54.6 ml (range 23.0 to 130.0) and mean residual volume presenting with retention was 602 ml (range 200 to 1,150). There were no intraoperative or postoperative adverse events except urinary infection in 2 patients. Mean catheterization duration was 6.3 days (range 3 to 18) and all patients became catheter-free postoperatively. Mean followup was 16.9 months (range 7 to 31). Mean maximum flow rate (+/-SD) was 11.2 ml per second (+/-5.7) 3 months after treatment. Mean International Prostate Symptom Score and quality of life scores decreased from 23.1 (+/-6.4) at baseline to 8.0 (+/-5.3) at 3 months (p <0.001), and 5.0 (+/-1.2) to 1.9 (+/-1.6, p <0.001), respectively. Mean estimated prostate volume decreased by 19.4% (54.6 to 44.0 ml) 6 months postoperatively (p <0.001). Only 2 patients had recurrent urinary retention during followup. CONCLUSIONS: Our study suggested that ILCP is a safe and effective therapy for patients with BPH presenting with acute urinary retention.

Acute Disease↗