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[Evaluation of research findings of potassium metabolism through biological modeling].

The cybernetic modelling of the water balance and the electrolyte balance has a heuristic value for the physiology and pathophysiology, by clearing up connections and open problems. This concerns problems of regulation size and regulation extension, but also the validity of reference values. Under this aspect is referred to the significance of steady state, input- and output inbalances and of the static and dynamic characteristics in the examination of the functional performance of the regulation circle. The static and dynamic compartment modelling is discussed at the instance of the potassium balance and exemplarily confirmed by findings of examinations. Here is referred to the special information value of the dynamic compartment analyse, as apart from the pool sizes (capacities) also intracorporal turnover rates (effects) are established.

Humans↗

[Biological modelling of potassium metabolism].

1. General principles of the modelling of compartments were described with the aim to use this methodology for the investigation of the potassium metabolism. 2. For the modelling of the potassium metabolism the necessary processes of investigation and calculations in the analysis of 42-potassium-kinetics were described in detail at an example. 3. By analogy references to the haemodynamics the general significance of the modelling of compartments was explained.

Adult↗

[Energy homeostasis and natural biological models].

Phase analysis of cardiac cycle was performed in normal subjects of both sexes aged 18-20 years at winter and summer seasons. It was found that the energy dependent systolic phases (isometric contraction, period of expulsion) have a definite continuance in connection with energy background, typological and sexual features of the homeostasis. The data evidence that the systolic phases can be considered as informative model for the study of energy homeostasis.

Adolescent↗