PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “NEOPLASM THERAPY”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed1976

[The use of nuclear medicine methods for the control of regional cytostatic therapy of neoplasms in the orofacial region].

Complementary to the well-known clinical, radiographic, histologic and biochemical methods for the control of the regional cytostatic chemotherapy of malignant tumours in the orofacial region, the authors describe by help of a case report the possible uses of nuclear-medical methods of examination. The following nuclear-medical methods of examination were employed: 1. bone scintigraphy, 2. perfusion scintigraphy, 3. tumour scintigraphy. The advantages of nuclear-medical methods consist in the relatively low load to which the patient is subjected and in the possibility of assessing qualitatively and quantitatively (in combination with current control methods) the distribution of the perfused chemotherapeutic agent and of evaluating the therapeutical success.

Aged↗
PubMed1981

[Adrenal cortex extract in the supportive therapy of neoplasm patients].

A high-title (2000 UCD) adrenal cortex extract was used in the support management of 30 neoplastic patients. Evaluation was based on performance status (PS) according to Karnofsky and symptom incidence before and after the treatment. PS improved in 30%. There was a marked reduction in asthenia and anorexia, with significant changes in headache, nausea, and vomiting. Blood pressure, heart rate, and the blood chemistry picture were not altered.

Adrenal Cortex Hormones↗
PubMed1988

Cardiac neoplasms: current diagnosis, pathology, and therapy.

Cardiac neoplasms remain enigmatic because of their rarity and protean clinical manifestations. Although surgery for benign cardiac neoplasms seems straightforward, certain difficulties in diagnosis and extirpation often exist. Newer diagnostic modalities including intraoperative transesophageal echocardiography seem promising and may provide better planning for the surgeon. Moreover, cardiac transplantation has provided relief for some patients with irresectable benign neoplasms. As ventricular arrhythmias may emanate from benign tumors, electrophysiologically guided extirpation may provide helpful control. Malignant cardiac tumors remain the true challenge, whether primary or metastatic, as little surgical or medical progress has resulted. This review examines nearly all diagnostic, pathological, histologic, and therapeutic aspects of benign and malignant cardiac tumors. Moreover, the various surgical approaches necessary for removal of resectable neoplasms are detailed.

Adolescent↗
PubMed1994

Electron beam intraoperative radiation therapy for pediatric neoplasms.

BACKGROUND: Intraoperative radiation therapy (IORT) has potential advantages over conventional external beam radiation in that a single large dose is delivered to the tumor and its regional bed at the time of surgical exploration. The therapeutic ratio is enhanced by direct tumor visualization, precise treatment volume, and exclusion of normal organs. In childhood, local tumor control is critical for lesions that cannot be totally excised or residual disease not ablated by systemic therapy. METHODS: During the past decade, the authors evaluated IORT in pediatric patients with unresectable or recurrent tumors. Fifty-nine patients were treated, 48 for advanced malignant disease and 11 for histologically benign but locally aggressive tumors. Sixty-four operations were performed, during which 84 separate radiation fields were used. High energy electrons at 5-11 MeV were delivered at a dose of 1000-1700 cGy to a tissue depth of 0.5-3 cm. RESULTS: Of 25 children with advanced neuroblastoma, 15 were alive 14-104 months (mean, 51 months) after treatment. The survival of all patients with solid malignancies was 63%. Local tumor control was achieved in 75% of children with cancer and 91% of those with benign tumors. Complications of IORT at the doses used were trivial. CONCLUSIONS: Electron beam therapy can be safely and efficiently delivered to young patients during operations intended to treat the primary tumor. The outcome achieved for overall survival and local control of the primary tumor is encouraging, and an acceptable complication rate during intermediate to long-term follow-up has been noted.

Adolescent↗