PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Paranoid Personality Disorder”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed2003

Personality traits and personality disorders in early onset versus late onset major depression.

BACKGROUND: We aimed to determine the relationship between certain personality disorders and/or personality traits and early onset major depression. METHODS: A total of 400 depressed primary care patients were assessed for personality disorders using the SCID screen and for personality traits using the Karolinska Scales of Personality (KSP) questionnaire. Early onset was defined as onset of the first episode before the age of 26. Logistic regressions were performed to reveal relationships after adjustment for sex, age and number of previous episodes. RESULTS: Both groups had a similar severity of current illness determined by the Montgomery-Asberg Depression Rating Scale. Those with an early onset presented with a more debilitating course, seen in the form of more depressive episodes and previous hospitalisations in spite of their younger age. Early onset was also an independent predictor for avoidant, borderline and paranoid personality disorders. It also predicted increased scores on the KSP scales Psychic anxiety, Psychasthenia, Muscular tension, Suspicion and Irritability, and decreased Socialisation. LIMITATIONS: The evaluation was performed as a self-assessment, subjects had a superimposed major depressive episode when assessed, and subgroups of individuals were not eligible. CONCLUSIONS: Early onset major depression is a predictor for personality pathology and deviant personality traits. A better understanding of the interplay between genetics and environment that underlies this phenomenon will help to improve the long-term course in afflicted individuals.

Adult↗
PubMed2007

The heritability of cluster A personality disorders assessed by both personal interview and questionnaire.

BACKGROUND: Personality disorders (PDs) as assessed by questionnaires and personal interviews are heritable. However, we know neither how much unreliability of measurement impacts on heritability estimates nor whether the genetic and environmental risk factors assessed by these two methods are the same. We wish to know whether the same set of PD vulnerability factors are assessed by these two methods. METHOD: A total of 3334 young adult twin pairs from the Norwegian Institute of Public Health Twin Panel (NIPHTP) completed a questionnaire containing 91 PD items. One to 6 years later, 1386 of these pairs were interviewed with the Structured Interview for DSM-IV Personality (SIDP-IV). Self-report items predicting interview results were selected by regression. Measurement models were fitted using Mx. RESULTS: In the best-fit models, the latent liabilities to paranoid personality disorder (PPD), schizoid personality disorder (SPD) and schizotypal personality disorder (STPD) were all highly heritable with no evidence of shared environmental effects. For PPD and STPD, only unique environmental effects were specific to the interview measure whereas both environmental and genetic effects were found to be specific to the questionnaire assessment. For SPD, the best-fit model contained genetic and environmental effects specific to both forms of assessment. CONCLUSIONS: The latent liabilities to the cluster A PDs are highly heritable but are assessed by current methods with only moderate reliability. The personal interviews assessed the genetic risk for the latent trait with excellent specificity for PPD and STPD and good specificity for SPD. However, for all three PDs, the questionnaires were less specific, also indexing an independent set of genetic risk factors.

Adult↗
PubMed1988

[Personality and psychopathology in patients with primary Sjögren's syndrome].

Twenty-one patients with primary Sjogrens' syndrome were investigated for hostility structure and psychiatric symptomatology. It was observed that they manifested high levels of hostility with an intropunitive direction in combination with highly scored delusional items of guilt and paranoid hostility. Acting-out hostility was in low levels. From the psychopathology point of view the majority of patients reported mainly depression and somatization, as well as anxiety and obsessive-compulsive symptoms. Unexpectedly paranoid symptoms were revealed in a substantial number of these patients. SS patients may present serious psychiatric symptoms and are in need of psychiatric help.

Adult↗
PubMed1977

The Odyssean personality. A survival advantage for carriers of genes predisposing to schizophrenia?

To explain the persistence of schizophrenia in human populations at relatively high and constant rates, it is proposed that the schizoid-paranoid personality (designated as the Odyssean personality) which characterizes so many nonpsychotic relatives of schizophrenics, represents a selective advantage. It is assumed that odyssean relatives carry the gene or genes predisposing to schizophrenia, but not in sufficient quantity for the development of the psychosis. It is suggested that because of their schizoid-paranoid out-look, Odysseans have an increased probability of contributing to the gene pool of succeeding generations since, in a world plagued by terror, strife, and war, they, rather than their trusting peers, are the ones more likely to survive long enough to ensure the survival of their progeny.

Adaptation, Psychological↗
PubMed1990

Psychiatric consequences of temporal lobectomy for intractable seizures: a 20-30-year follow-up of 14 cases.

Between 1958 and 1968, 14 patients from the epilepsy clinic at the University of Oregon Hospitals and Clinics with a diagnosis of temporal lobe epilepsy (TLE) had a temporal lobectomy for medically intractable seizures. Nine of the 14 patients operated on remained seizure-free over the 20-30-year period of follow-up. Between 6 months and one year following temporal lobectomy, two women, previously healthy from a psychiatric standpoint, developed psychoses, and the previous psychiatric problems of four other patients worsened. Two patients, one with incapacitating paranoid personality disorder and the other with explosive rage attacks preoperatively, had marked improvement in their psychiatric status following temporal lobectomy. The remaining six patients, all psychiatrically healthy prior to surgery, have had no change in psychiatric status following surgery. Development of psychosis or deterioration in psychiatric status after surgery was more common in patients with later age of onset, unreality or déjà vu rather than epigastric aura, pre-operative evidence of bilateral brain damage, and persistence of EEG or clinical seizure activity. Development of a chronic psychosis in psychiatrically healthy individuals many months after temporal lobectomy, even when seizures are arrested or ameliorated, suggests that anomalous synaptic regeneration may follow the surgery in these cases. Careful analysis of histories and outcomes may contribute to better understanding of the pathophysiology and anatomical substrates of psychoses.

Adult↗
PubMed2002

The effect of a history of alcohol dependence in adult major depression.

We examined 180 patients with a principal diagnosis of Major Depression, with or without a lifetime diagnosis of alcohol dependence. In the ever-dependent group, the GAF was lower; cannabis dependence higher; and Borderline, Schizotypal and Paranoid personality disorders more common. They reported more paranoia and interpersonal sensitivity on the Hopkins Symptom Checklist and more friction and interpersonal behaviour on the Social Adjustment Scale. On the Temperament and Character Inventory, novelty seeking was higher and persistence and cooperativeness lower. PBI scores and family histories did not differ significantly. Treatment outcome did not vary, except that subjects with lifetime alcohol dependence and current heavy drinking did less well.

Adult↗
PubMed1998

Silence in interview: psychiatry and the Argent conditions.

A man charged with serious sexual offences was advised by his solicitor not to answer the questions which were put to him during the police interview and in the absence of an appropriate adult whose assistance he had declined. At his trial, counsel for the prosecution wanted the jury to be allowed to draw an adverse inference from his silence. Psychiatric evidence was admitted to the effect that he had a paranoid personality disorder. On the basis of the ruling in R v. Argent 1997, in which grounds were set out for not allowing a jury to draw an adverse inference, it was submitted that the jury should not be allowed to draw an adverse influence. These grounds include mental capacity, state of of health, tiredness and personality. The trial judge accepted the submission.

Journal Article↗
PubMed2001

[The schizophrenic spectrum: an epidemiological viewpoint].

In epidemiological terms there is no clear demarcation between health and illness. This is also true for the schizophrenic spectrum, where sub-clinical (sub-syndromal, sub-diagnostic) syndromes embrace schizotypical, schizoid and paranoid personality disorders and personality features, which in the general population are much more prevalent than schizophrenias themselves. Early recognition of risk cases and mild cases is decisive for prophylaxis. Several diagnostic instruments are available for this purpose, but satisfactory confirmation of their predictive power and validity by prospective studies is lacking. Alongside traditional, clinical research on schizophrenia, future epidemiological research, focusing increasingly on the whole schizophrenic spectrum, may be expected to yield important new insights confirming a dimensional rather than a categorical distribution of traits and syndromes and providing powerful arguments against the discrimination and stigmatisation suffered by schizophrenic patients.

Culture↗
PubMed1987

A matched-paired comparison of treated versus untreated schizophrenia spectrum cases. A high-risk population study.

As a part of the American-Danish prospective study of children of schizophrenic mothers, psychiatrically hospitalised and untreated cases of schizophrenia spectrum conditions, i.e. borderline schizophrenia, schizoid and paranoid personality disorders, were compared on a number of characteristics. This exploratory analysis revealed that the groups were similar to each other on childhood conditions, sociodemographic variables, premorbid IQ and levels of schizophrenia-related psychopathology. The hospitalised group, however, exhibited higher levels of concomitant psychopathology, such as substance abuse, affective symptoms and psychopathic tendencies. It is suggested that the clinical population may not be representative of the diagnostic category in question owing to co-existence of confounding symptomatology (Berkson's fallacy).

Adolescent↗
PubMed1976

A relationship between Eysenck's P scale and change in muscle action potentials with attention to perceptual tasks.

An experiment is described in which an index of change in muscle tension produced by perceptual discrimination tasks, and scores on Eysenck's PEN scales, were measured on 39 university students. It was hypothesized that if P is an index of psychoticism, as has been claimed (Eysenck & Eysenck, 1968) then an index of one central feature of so called 'psychotics', namely attention difficulty while decision making, should correlate positively with P. P was found to correlate significantly with a measure of increase of EMG on the perceptual discrimination tasks (r = 0-54, P less than 0-001). Correlations of this index with N and E were zero. The results are considered to be particularly significant, since scores on P, E and N gave almost zero intercorrelations in the sample tested, and L scores were exceedingly low. Further evidence is provided which suggests that both P and muscle tension increase are directly related to the degree of endorsement of paranoid ideas.

Action Potentials↗
PubMed1977

Distinction between male and female invested partners in sexual disorders.

Using the SCL-90, a self-administered symptom inventory, the authors evaluated 48 sexually asymptomatic male and female partners (invested partners) of sexually dysfunctional men and women. They found that the male invested partners showed significantly more psychological symptoms than the female invested partners but about the same symptom distress levels as sexually dysfunctional men. The authors hypothesize that the reason for this gender-specific difference in distress levels of invested partners is society's definition of the male's role as the responsibe partner regarding satisfaction in sexual relationships.

Adult↗
PubMed1985

Psychiatric aspects of traffic accidents.

The authors review the literature pertaining to the roles of psychopathology and personality variables in traffic accidents. They review studies of nonpsychiatric and psychiatric samples and examine the roles of suicide, life events, alcohol, and drugs. Certain personality characteristics and psychopathology--such as low tension tolerance, immaturity, personality disorder, and paranoid conditions--appear to be risk factors for traffic accidents. Although the role of alcohol is relatively well established, the roles of most other drugs are less clear. The results of further investigation of psychopathology's role in traffic accidents may have implications for prevention.

Accidents, Traffic↗
PubMed1994

A case of paranoid disorder associated with hyperthyroidism.

This paper describes a patient presenting with paranoid symptoms who eventually was diagnosed as having Graves' disease. In this patient, paranoid disorder appeared to occur concurrently with hyperthyroidism in a clear state of consciousness. This case underscores the need to maintain a high index of suspicion of possible medical conditions in psychiatric patients. This is especially the case in the presence of unexplained symptoms and when there is a difficulty communicating with the patient. The importance of carrying out a careful physical examination on admission to a psychiatric unit is emphasized. Another indication for further medical investigation in a patient with psychiatric symptoms is the absence of a psychological explanation for a worsening of the psychiatric symptoms.

Adult↗
PubMed1988

Psychiatric and legal aspects of persistent litigation.

There is a paucity of literature in English about those people who persistently complain. In Germany and in Scandinavia, a diagnosis of querulent paranoia may be made, although this interesting and uncommon syndrome is rarely recognised in the UK. Five cases of litigiousness or persistent complaining are reported, to illustrate the typical psychopathology and the types of diagnosis that occur. Four of these people are barred from further litigation by the courts (vexatious litigants) and were contacted directly for the purpose of this study.

Adult↗