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Comparison of an extrusion procedure and eversion procedures in the treatment of hydrocele.

In a prospective randomized study, the "extrusion" operation modified by McGowan Jr. and Howley and the conventional "eversion" operations were compared with each other in terms of early and late postoperative complications in the treatment of idiopathic scrotal hydrocele. As early complications with the "extrusion" procedure a total of 4 (11.4%) cases were seen: 3 oedemas and 1 epididymitis; and with the "eversion" procedures there were 18 (51.4%) early complications: 3 haematomas, 12 oedemas and 3 wound infections (11.4 vs. 51.4%, p < 0.05). In the late ones 1 recurrence and permanent testicular pain were seen with the "extrusion" procedure.

Adult↗

Free graft patch 1-stage procedure to repair penile hypospadias unsuitable for the flip-flap procedure: indications and experience.

From January 1983 to December 1985, 14 procedures were performed in which a free graft of skin from either the foreskin or elsewhere was substituted for the flipped flap in the repair of hypospadias. This obviates the problem of thin skin below the urethral meatus, since a flipped flap in such a case will result in devascularization of the flap. Moderate chordee was not necessarily a contraindication to the use of this procedure, provided the chordee could be corrected without moving the meatus proximally. Cosmetic and functional results have been good, and there was only 1 urethral fistula. Nevertheless, because of the need for a scrotal flap of fat to prevent fistula formation and to ensure vascularization of the graft, and because of the availability of a vascularized flap from the foreskin in most cases, the free graft patch procedure is best reserved for cases in which the foreskin is either absent or deficient.

Adolescent↗

The role of adjunctive mitomycin C in secondary glaucoma triple procedure as compared to primary glaucoma triple procedure.

OBJECTIVE: This study aimed to investigate whether previously failed glaucoma filtration surgery is a risk factor for filtration failure of subsequent trabeculectomy combined with cataract surgery and to determine the role of adjunctive mitomycin C (MMC) in the secondary glaucoma triple procedure (SGTP) as compared to primary glaucoma triple procedure (PGTP). DESIGN: A prospective, controlled study that was randomized with respect to assignment to adjunctive MMC and a case-control design with respect to comparisons between SGTP and PGTP was studied. PARTICIPANTS: The SGTP group consisted of 49 eyes of 49 consecutive patients with primary open-angle glaucoma with a history of glaucoma filtration surgery requiring glaucoma medical therapy and in need of cataract surgery, randomized to adjunctive MMC (SGTP MMC subgroup of 21 eyes) and no adjunctive MMC (SGTP control subgroup of 28 eyes). The PGTP group consisted of 49 PGTP cases closely matched to the SGTP cases with respect to age, race, gender, MMC use, C:D ratio, and systemic diseases. INTERVENTION: Trabeculectomy combined with phacoemulsification and a small incision (5 x 6 mm), all polymethylmethacrylate posterior chamber intraocular lens implantation with or without adjunctive MMC (0.5 mg/ml for 1 minute), was performed. MAIN OUTCOME MEASURES: Surgery failure was defined as the need of an additional intraocular procedure or the need of more than one medication to achieve intraocular pressure control to the target level. Intragroup and intergroup comparisons were made with respect to filtration outcome among the SGTP and PGTP patients. RESULTS: Without adjunctive MMC, filtration success was significantly less in SGTP than in PGTP (P = 0.03). Adjunctive MMC significantly increased the success rate of SGTP (P = 0.02) but not that of PGTP (P = 0.89) over the average follow-up period of 2 years. CONCLUSIONS: Previously failed glaucoma filtration surgery is a significant risk factor for the filtration failure of combined surgery. Intraoperative use of adjunctive MMC significantly improves the filtration success rate of SGTP.

Adult↗

A prospective cost evaluation related to allogeneic haemopoietic stem cell transplantation including pretransplant procedures, transplantation and 1 year follow-up procedures.

The Norwegian Ministry of Health and Social Affairs recently introduced activity-based financing for hospitals partly based on diagnosis-related groups (DRG). We soon observed that there seemed to be a considerable discrepancy between the reimbursement amount and the real cost of allogeneic haemopoietic stem cell transplantation. It was therefore decided to undertake a prospective micro-cost analysis to define a more realistic reimbursement. To identify real costs, we undertook a registration of pre-transplant procedures, transplantation and 1 year follow-up costs, including harvesting, personnel costs, clinical and laboratory procedures, together with blood products and drugs related to patients and donors. These data were compared to hospital DRG reimbursement. This information was registered for 17 consecutive patients, with a mean age 40 years (range 17-58 years). Ten patients had chronic myeloid leukaemia, three had acute lymphatic leukaemia, two had acute myeloid leukaemia and two had myelodysplastic syndrome. The data analysis showed a mean cost of US$ 106825 (NOK 901982), (range US$ 42376-362430). The average actual hospital revenue (50% DRG reimbursement + income related to length of stay + special procedure funding) was US$ 36404 (range US$ 26228-55998). Activity-based financing as applied in Norway, under-compensates hospital costs for allogeneic bone marrow transplantation. The government should make realistic estimates of real costs before introducing financial reforms in the health care system.

Adult↗

[The Epping resection-suspension arthroplasty procedure. A standard procedure in the operative treatment of trapeziometacarpal osteoarthrosis?].

The surgical treatment of painful osteoarthrosis of the trapeziometacarpal joint with the Epping technique consists of excision of the trapezium and reconstruction of the first intermetacarpal ligament by using the distally based half of the flexor carpi radialis tendon. This ligament reconstruction procedure aims to prevent proximal migration of the first metacarpal, restore function and stability of the neoarthros. This retrospective study presents operative outcome results after using the Epping arthroplasty technique. The Epping technique has been performed in seventy cases and could be evaluated after a mean follow-up of 34.6 months in 92.4 % of all operated patients. Subjective results were evaluated using patient-based questionnaires such as the Buck-Gramcko-Score and the German Version of the DASH V2.0 questionnaire. Objective and functional outcome analysis including range of motion, strength measurements with the computer-based JAMAR dynamometer and various X-ray views, have been used as further methods of evaluation. Excellent pain relief and very good subjective results with 86 % patient satisfaction have been reported by our patients. The objective outcome analysis demonstrated good functional results with respect to radial abduction (51 degrees) and palmar flexion (45 degrees), and improvement in grip strength, key pinch and pulp pinch. Some patients reported remaining problems with pain during performance of activities of daily life and professional activities. A significant proximal metacarpal migration without correlation to the objective or subjective outcome was found in follow-up X-ray controls. The Epping ligament reconstruction procedure has proven to be a valuable standard procedure after a mid-term follow-up period. Good functional outcome and high patient satisfaction could be achieved, but some patients still remain with problems in different activities. Long-term results still need to be evaluated.

Adult↗

The Kropp-onlay procedure (Pippi Salle procedure): a simplification of the technique of urethral lengthening. Preliminary results in eight patients.

OBJECTIVE: To lengthen the urethra to increase bladder outlet resistance in adolescent girls with a neurogenic bladder. PATIENTS AND METHODS: During a 2-year period (1992-94), eight girls (mean age 13.5 years, range 9-19) underwent a Kropp-onlay urethral lengthening associated, for six of them, with a bladder augmentation. Seven of the eight patients patients were spina bifida and confined to a wheelchair. One patient had had a previous transverse myelitis. A Benchekroun hydraulic value (in three cases) and a Malone procedure (in two cases) were performed at the same stage. The technique of Kropp-onlay urethral lengthening, which creates a flap value mechanism which leaks when the bladder is too full, is described and illustrated. RESULTS: Seven of eight patients were dry during the day and four were occasionally damp during the second part of the night. One could not be dry for more than 2 h during the day but had a very hyperactive detrusor. She developed two bladder stones which required an open vesicotomy. One developed a urethral fistula requiring a second Kropp-onlay procedure and became dry afterwards. Two patients, who did not undergo a bladder augmentation, needed oxybutinin therapy to obtain a satisfactory result. Post-operative urodynamic measurements are discussed. CONCLUSION: The Knopp-onlay urethral lengthening is easier to perform than the original Kropp procedure. The preliminary results are similar to those of alternative techniques (e.g. urethral suspension) but long-term reliability of this technique remains unknown.

Adolescent↗

Ophthalmologic procedures in the emergency department--Part II: Routine evaluation procedures.

The emergency physician (EP) must be familiar with performance of ophthalmologic procedures for evaluation and treatment of a multitude of eye complaints. This article is the second of three articles addressing ophthalmologic procedures potentially of use by the EP. This article reviews the indications and the techniques for the following routine procedures: visual acuity testing, pupil dilatation, topical anesthesia use, and tonometry. Criteria for consultation also are addressed.

Anesthesia, Local↗

A general regression procedure for method transformation. Application of linear regression procedures for method comparison studies in clinical chemistry, Part III.

The biometrical treatment of laboratory data may require the estimation of a regression line for the transformation of one set of measurements to another. The regression procedure introduced in part I (1) of our work does not always yield unbiased results in such situations, since its estimators are not scale invariant. In part III we present the parameter estimation of a general regression equation which is scale invariant and retains all properties of the method comparison procedure, in particular its robustness. Its application is demonstrated by several examples, and the results are compared with other robust biometrical procedures. The mathematical aspects are explained in the appendix.

Biometry↗

Increasing compliance with medical procedures: application of the high-probability request procedure to a toddler.

The effects of high-probability (high-p) requests on compliance with low-probability (low-p) responses have received increased attention from applied investigators. This study examined the effects of a high-p procedure on a toddler's compliance with medical procedures. Compliance to low-p requests occurred more frequently following compliance to high-p requests, suggesting that this procedure may be useful across different topographies of compliance.

Behavior Therapy↗

Complications of catheter cerebral arteriography: analysis of 5,000 procedures. III. Assessment of arteries injected, contrast medium used, duration of procedure, and age of patient.

Complication rates in 5,000 consecutive catheter cerebral arteriograms were assessed with regard to arteries injected, contrast medium used, patient age, and duration of procedure. No statistically significant difference was found between the complication rate when the carotid artery alone was injected and that when the carotid artery was injected in combination with the vertebral artery, the aortic arch, or both. There was also no significant difference between the total complication rates using Conray-60 and Renografin-60. However, although Conray-60 demonstrated no change in complication rate with increased volume, Renografin-60 showed a consistent and significant increase in complication rate with increased volume. Complication rates were also significantly higher when the procedure lasted more than 80 min and in patients more than 40 years old. As might be expected, nontraining hospitals used significantly less contrast material and had significantly shorter procedures than training hospitals.

Adult↗

[A case report of Konno procedure for Ebstein's anomaly with subaortic stenosis after Hardy procedure and repair of coarctation and VSD].

A rare case of Ebstein's anomaly with coarctation and VSD is reported. Severe subaortic stenosis and LV dysfunction were progressed after PA banding and coarctation repair at four months old and Hardy procedure and VSD closure at five month old. Konno procedure was successfully performed with SJM 21A at one year and nine months old. Since coarctation type VSD may cause subaortic stenosis after its closure due to posteriorly deviated infundibular septum, anterosuperior margin of VSD would occasionally better to be eliminated at the time of VSD closure. This is the youngest one of Konno procedure to our knowledge.

Aortic Coarctation↗

Invasive cardiac procedures after myocardial infarction: which procedure when and its relationship to thrombolysis.

The availability and the now routine use of thrombolytic agents are important advances for therapeutic cardiology and the emergency care of patients experiencing AMI. The progression from ischemia to necrosis of cardiac muscle now can be aborted in a portion of this population by initiating thrombolytic infusions. Early use of thrombolysis in these patients has reduced acute myocardial infarction mortality and morbidity significantly. Although thrombolytic therapy has changed the course of treatment and survival after AMI, there may be time when this approach is contraindicated or unsuccessful. Alternative treatments that may be considered when thrombolytic agents cannot be given, or fail to ameliorate ischemia, are emergent percutaneous transluminal coronary angioplasty or coronary artery bypass graft surgery. Future interventional procedures such as intracoronary stents, atherectomy devices, and lasers may be considered as emergent treatment in the near future. It is important to have reviewed when these alternative invasive procedures, some of which are currently experimental, might be considered. Indeed, interventional procedures such as intracoronary stents, atherectomy devices, and laser delivery systems eventually may be accepted as primary therapies for the patient who arrives in the emergency department with an AMI. In the meantime, thrombolytic therapy administered as urgently as possible to appropriate patients with myocardial infarction is the most important goal.

Algorithms↗

[Limb salvage procedures in malignant bone tumors of the extremities, with special reference to the various reconstructive procedures of bone defects].

The outcomes of 31 cases of limb salvage procedures for malignant bone tumors performed between 1974 and August 1988 were investigated. The age at operation ranged from 7 to 76. Thirteen cases were growing children under 15. The site of lesions were humerus in 6 cases, femur in 20, tibia in 3 and fibula in 2. Pathological diagnoses were osteosarcoma in 19, chondrosarcoma in 5 and others in 7. Reconstructive procedures were performed in 28 cases, consisting of endoprosthetic replacements in 18, vascularized fibula grafts in 6 and free autogenous bone grafts in 4. Two cases of osteosarcoma recurred, and amputations were performed. Six cases died of pulmonary metastases, while 22 cases (71%) are alive and free of disease. Functional results depended mainly on the size and site of resection rather than on the reconstructive procedures, and were generally good in the proximal femur and fibula, and poor in the distal femur and proximal tibia. Discrepancy in the length of lower limbs occurred in 8 cases of growing children; 5 of 6 vascularized fibula grafts showed thickening of the grafted bones, and one of them grew by 2.5 cm in length. Endoprosthetic replacements are adequate for hip and shoulder regions, and for low grade sarcoma which does not require chemotherapy or irradiation. Free autogenous bone grafts are good for narrow defect of bone, and cases of arthrodesis of joint. Vascularized fibula grafts are adequate for the upper limb, and lower limb of growing child.

Adolescent↗

Computer evaluation of statistical procedures, and a new quality-control statistical procedure.

I describe a program for definitive comparison of different quality-control statistical procedures. A microcomputer simulates quality-control results generated by repetitive analytical runs. It applies various statistical rules to each result, tabulating rule breaks to evaluate rules as routinely applied by the analyst. The process repeats with increasing amounts of random and systematic error. Rate of false rejection and true error detection for currently popular statistical procedures were comparatively evaluated together with a new multirule procedure described here. The nature of the analyst's response to out-of-control signals was also evaluated. A single-rule protocol that is as effective as the multirule protocol of Westgard et al. (Clin Chem 27:493, 1981) is reported.

Chemistry, Clinical↗

A new revascularization procedure for extensive arterial occlusions of lower extremity. A.V shunt procedure.

A revascularization procedure for extensive arterial occlusive lesions of the lower extremity, namely "A-V shunt procedure" was devised. The occluded popliteal artery is recanalized by open endarterectomy in association with E-PTFE bypass for occlusion of the superficial femoral artery, and the patency of reconstructed arterial segments is ensured by an arterio-venous shunt created at the distal end of the recanalized tibio-peroneal trunk. The branches of the genicular arterial network are also reopened by a technique of thrombectomy. Numerous collaterals develop through the reopened genicular network increasing blood flow to the ischemic distal areas. From 1967 to 1980, 63 extremities in 57 patients, which had extensive arterial occlusions of lower extremities with impending ulcer and/or severe rest pain in their feet or toes, underwent this procedure. Remarkable improvement of ischemic symptoms resulted in 76.2% of extremities at the time of the hospital discharge and 57.1% in follow-up.

Adult↗

[Comparative analysis of various plasmapheresis methods--modern procedures of mechanical plasma collection compared with each other and with manual bag centrifugation procedures].

Four plasmapheresis procedures (manual blood bag centrifugation plasmapheresis, and the three plasmapheresis machines P.C.S./Haemonetics, Autopheresis-C/Baxter-Travenol, Plasmapur Monitor/Organon Teknika) were studied comparatively. The three machine procedures could be performed more easily and more rapidly and were well accepted by donors, autologous donors (patients) and staff. Compared with the traditional, well established manual procedure, a possible impairment of the plasma donors seems reduced rather than raised. Activation of the hemostatic system of the donors, measured with very sensitive methods, was found to be less pronounced when plasmapheresis was performed with the machines than when it was performed conventionally. The plasma product obtained by machine plasmapheresis was found to be of higher quality. All three systems showed less activation of the clotting system. Especially the plasma obtained by the P.C.S. showed a higher clotting factor yield. Plasma obtained by the Autopheresis-C and by the Plasmapur Monitor (both systems are equipped with filters) was markedly less contaminated with cells. The recently found low activation of the clotting system of plasma recipients, however, showed no differences when plasma obtained conventionally or by the Plasmapur Monitor was used. In summary, the new machine plasmapheresis devices offer a good alternative to the conventional blood bag centrifugation method and set new standards for the production of high quality plasma.

Blood Coagulation Tests↗

Comparison of D10-value accuracy by the limited Spearman-Karber procedure (LSKP), the Stumbo-Murphy-Cochran procedure (SMCP), and the survival-curve method (EN).

The decimal reduction time (D10) may be determined by any of several methods, including the limited Spearman-Karber procedure (LSKP), the Stumbo-Murphy-Cochran procedure (SMCP), and the survival-curve method (EN). The International Organization for Standardization (ISO) endorses the LSKP and the EN. Most Japanese and German industries utilize the SMCP and the EN for calculation of the D value. A presentation at an ISO meeting suggested that the SMCP was less accurate than the LSKP, and the ISO recommended abandoning the SMCP. The paper concerning the accuracy comparison among these methods has not been published. Therefore, in order to examine whether the SMCP was truly inferior to the LSKP, the Japanese delegates to the ISO compared the accuracies of D10 values obtained with these methods by simulation and in experimental procedures using a biological indicator (BI) and a biological indicator evaluator resistometer (BIER) with ethylene oxide gas sterilization. The results indicate that the SMCP was not consistently less accurate than the LSKP in determining D10.

Colony Count, Microbial↗

The indications for and techniques and outcomes of ablative procedures of the distal ulna. The Darrach resection, hemiresection, matched resection, and Sauvé-Kapandji procedure.

Several ablative procedures exist for the treatment of distal radio-ulnar joint arthritis. This article describes the indications, techniques, pitfalls, and outcomes for the four most popular procedures: Darrach, hemiresection-interposition, Sauvé-Kapandji, and matched ulnar resection. The authors explain their personal algorithm for treatment selection, emphasizing patient requirements versus the physiologic characteristics of each procedure.

Arthritis↗