Updated Hodgkin's disease. Comment: the reclassification of Hodgkin's disease.
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In the present study a re-classification of 96 lymphomas of the epipharynx and the mesopharynx including tonsils, paranasal sinuses and neck region was performed using the Kiel-classification. The histological criteria employed for this procedure were described briefly. 33 cases could be diagnosed as lymphomas of low grade malignancy, 50 cases belonged to the group of high grade malignancy and 13 cases remained unclassifiable. There was a light preponderance of male patients in the whole lymphoma group. The most frequent tumors were immunoblastic lymphomas, followed by immunocytomas, lymphoblastic lymphomas, centroblastic lymphomas, centroblastic/centrocytic and centrocytic lymphomas. Examples of transitions of one lymphoma type into another were demonstrated. The fact must be mentioned that lymphomas of the paranasal sinuses were nearly completely of the immunocytic or immunoblastic type.
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Study of lipid and DNA, biochemical tests and phage typing performed on the strain PA previously labelled Mycobacterium phlei, lead to the conclusion that this strain belongs to the species M. smegmatis. Parallel studies performed on strain PN, isolated from a culture of strain PA, as well as DNA homology percentage of the two strains, do not support the assumption that strain PN could have resulted from a mutation of strain PA Strain PN produces mycolic acids similar to those found in Rhodococcus bronchialis; the few biological tests applied quite agree with such a classification.
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