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At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

A comprehensive study on lesions of the pinna.

PURPOSE: Pinna contributes enormously to the facial aesthesis. Lesions affecting the pinna can lead to overt disfigurement and change the entire appeal of the face. Gross deformity can occur because of a delay in diagnosis and mismanagement. The aim of our study was to determine the clinical presentation, relevant investigations, appropriate treatment, timing of surgical intervention, and complications encountered. Factors that predispose and aggravate the condition and their appropriate management are also discussed. The point to be emphasized is that a good clinical history and examination alone is sufficient to diagnose the conditions without the aid of any special investigation. MATERIALS AND METHODS: Our clinical study comprised of 307 cases of men and women patients presenting with swelling of the pinna, who attended the Ear, Nose, and Throat Department, Kasturba Medical College, Mangalore, India, during the period of February 1992 to June 2002. Wide bore needle aspiration was done for the majority of cases of seroma and hematoma. Patients who had recurrence were managed by window procedure. Incision and drainage with or without curettage of diseased cartilage was performed for perichondritis. Other lesions like keloid, hemangioma, dermoid cyst, sebaceous cyst, and malignancy were managed by complete excision. A firm pressure dressing was applied in all cases after surgery. Majority of the cases were done under local anesthesia. RESULTS: Prompt surgical intervention under good antibiotic cover gave excellent results with minimal complications. CONCLUSIONS: Surgical intervention at the earliest followed by a firm pressure dressing under antibiotic cover decreases the morbidity. Diabetes mellitus plays a significant role in few of the conditions and has to be simultaneously controlled.

Adolescent↗
PubMed2003

Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma.

The incidence of thyroid carcinoma in familial adenomatous polyposis (FAP) is thought to be 1%-2%, with the majority of cases being female. We have investigated the phenotype and genotype of 16 patients with FAP associated thyroid carcinoma. Among 1194 FAP patients studied in two high risk registries in North America (Familial Gastrointestinal Cancer Registry, Toronto and University California, San Francisco), 16 (1.3%) unrelated patients with FAP associated thyroid cancers were identified. Adenomatous polyposis coli (APC) gene testing was performed in 14 of the 16 cases. The average age of diagnosis for FAP and thyroid carcinoma was 29 years (range 17-52 years) and 33 years (range 17-55 years), respectively. All FAP patients except 1 had more than 100 colonic adenomas. Extracolonic manifestations, beside thyroid cancer, were presented in 81% (n = 13) of the patients, including gastric and duodenal polyps, desmoid tumor, osteoma, epidermoid cyst, sebaceous cyst and lipoma. Colorectal cancer was diagnosed in 38% (n = 6) of the patients. The pathology of the FAP associated thyroid cancer was predominantly papillary carcinoma. Germline mutations were identified in 12 of 14 patients tested. Mutations proximal to the mutation cluster region (1286-1513) were detected in 9 cases. Thyroid cancer in our FAP population was rare, predominantly in females and showed papillary carcinoma histology. Additionally, thyroid cancer in our patients occurred in the setting of classic FAP phenotype. Germline mutations were located predominantly outside the APC mutation cluster region.

Adenomatous Polyposis Coli↗
PubMed1988

A-scan ultrasonography in the diagnosis of orbital dermoid cysts.

Eleven patients with anterior and deep orbital masses had A-scan ultrasonography. The ultrasonograms were all similar and demonstrated a dermoid-like pattern of low internal reflectivity and a high-rising, double-peaked posterior surface spike. Although the postoperative pathologic findings in seven cases confirmed the clinical diagnosis of dermoid cyst, other lesions, such as epidermoid cyst, sebaceous cyst, Graves's myopathy, and Ewing's sarcoma were found to show a similar ultrasonographic pattern. This stresses the importance of computed tomography in the diagnosis of orbital tumors.

Adolescent↗
PubMed1976

Steatocystoma multiplex.

Steatocystoma multiplex is a poorly understood clinical condition characterized by numerous cutaneous cysts. The lesions can be confused with milia, epidermal inclusion cysts, sebaceous cysts, dermoids, and the cysts of acne vulgaris. This patient has hypotrichosis and multiple milia-like cysts on the face and scalp, showing the histologic characteristics of steatocystoma multiplex.

Adolescent↗
PubMed1980

Benign lymphoepithelial parotid cyst with sebaceous differentiation--cystic sebaceous lymphadenoma.

A case of benign lymphoepithelial parotid cyst with sebaceous differentiation, or cystic sebaceous lymphadenoma, in a 57-year-old white man is presented. The literature on lymphoepithelial cysts and sebaceous lymphadenomas of the parotid gland is reviewed, and the alternative hypotheses of "branchial cleft origin" and "intranodal salivary gland inclusion origin" are compared. This case lends support to the intranodal glandular inclusion theory for lymphoepithelial cysts of the parotid.

Cysts↗
PubMed2002

Squamous cell carcinoma arising in a giant epidermal cyst: a case report.

Epidermal cysts are commonly encountered in surgical practice. Malignant degeneration of epidermal sebaceous cyst is uncommon. The authors report the case of a 38-year Filipino woman presenting with a voluminous sebaceous cyst of the left buttock. Ultrasonography and computer tomography were made preoperatively without any hint of eventual malignant degeneration. Marginal excision was performed with direct closure of the skin. The histological examination revealed epidermal sebaceous cyst with squamous cell carcinoma in situ, which is a quite rare, but well known complication occurring in sebaceous cysts.

Adult↗
PubMed1991

Eruptive vellus hair cysts with sebaceous glands.

A patient is described who had eruptive vellus hair cysts with and without sebaceous glands in the cyst walls. An association is suggested between eruptive vellus hair cysts and the condition of steatocystoma multiplex.

Adult↗