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Results for “SHOCK/experimental”

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Relationship of stress-induced histidine decarboxylase to circulatory homeostasis and shock.

Histidine decarboxylase activity of mouse tissues is increased by stress and by injection of epinephrine and norepinephrine, suggesting a balance between histamine and catechol amines producing a component of circulatory homeostasis. Imbalance during intense stress might lead to failure of circulatory homeostasis and to shock. Reasons for discounting histamine as "shock toxin" may be invalid.

Amines↗

Studies on reanimation with plasma expanders.

In dogs very severe haemorrhage, which leads to a state barely distinguishable from death, can be cured by one intra-arterial injection of dextran equal in volume to three-quarters or more of the estimated blood loss, provided that the dextran injection contains adrenaline and lobeline. Recovery after this treatment is only temporary, and a blood transfusion of about 25% of th e subject's lost volume of blood is needed for complete recovery. It may be possible to apply these results to man, in which case, the reanimation method of Negovsky could be simplified and therefore be easy to use in any circumstances.

Animals↗