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PubMed1991

[Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms].

We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.

Adenocarcinoma↗
PubMed1993

[A preliminary assessment of the efficacy of anticancer measures in malignant stomach neoplasms].

Anticancer prophylactic and treatment measures are approved initially among small populations contingents and, hence, their results are not essentially effecting demographic values. Changes of the state of selected contingents are evaluated by means of lethality or survival values. On the example of gastric cancer patients survival, the authors determine the period of observation necessary for preliminary evaluation of the efficiency of anticancer measures. During 5 years there was no clear change of survival of patients with gastric cancer of stage I-II (P > 0.05). The duration of the period of statistically valid reduction (P < 0.001) of the survival of patients with gastric cancer (stage III-IV) was two years. Thus, changes of the level of two year survival in patients advanced gastric cancer under the effect of anticancer measures may be used for express-evaluation of these measures.

Female↗
PubMedDate not supplied

[Present day radiation diagnosis of upper stomach neoplasms].

The paper analyzes over 3000 diagnosed gastric carcinomas. In the author's opinion, a drastic rise in the incidence of carcinomas of the upper stomach (as high as 60-65%) and the change in its anatomy common to gastric cancer--predominance of diffuse (endophytic) forms require a substantial correction of the present approaches to its detection. The paper gives the main points of radiation diagnosis (classic X-ray study, double contrasting, CT) for endophytic carcinomas at this site. In the author's opinion, nearly, as a rule, endoscopically diagnosed carcinomas of the lower esophagus and frequently involvement of the midesophagus are intramural carcinomas of the upper stomach with infiltration swiftly affecting the esophagus. The author considers radiation therapy to become a main method for detection of upper gastric carcinoma. He thinks that the active use of radiation techniques will also substantially expand diagnostic possibilities in these gastric carcinomas and will choose the most optimum plan of their surgical treatment.

Adenocarcinoma↗