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PubMed1984

Population and social security projections for Bangladesh.

The author presents population projections for Bangladesh using data from the 1981 census, U.N. sources, and other official and nonofficial sources. "Confidence intervals for year 1986 and year 2001 populations for Bangladesh are developed. Rural-urban shifts in population are analyzed through Markov chains, and reveal a significant projected redistribution to urban areas. A study is presented of the actuarial cost of a potential social security program designed to meet the financial needs of an increasing set of urban dwellers.... Aggregate projected contributions and benefits for the years 1975, 2005, 2015, and 2025 illustrate the possible program."

Asia↗
PubMed1983

Birthweights in Goroka and Kainantu Hospitals.

Birthweight data for 4474 live, healthy, singleton, full-term births of 2000g or over were analysed. The mean birthweights were 3136 +/- 445g at Goroka, and 3106 +/- 473g at Kainantu. Birthweights varied with sex, region of maternal origin, season and birth order, but not with year. Significant influences on Goroka birthweight values were, in order of importance, birth order, sex and season.

Birth Order↗
PubMed2002

Spatial distribution and sampling plans for Mesoplatys ochroptera (Coleoptera: Chrysomelidae) on sesbania.

With the widespread introduction of the nitrogen-fixing legume sesbania, Sesbania sesban (L.) Merril, in agroforestry systems, the defoliating beetle Mesoplatys ochroptera Stål has become a serious pest of the trees in Africa. To determine within-field and within-plant spatial distribution of M. ochroptera on both seedlings and trees of sesbania, distribution statistics were computed using Iwao's mean crowding regression model. In 1- to 3-mo-old seedlings, the model accounted for 29.8, 32.2, and 61.0% of the variation observed in mean crowding to mean relationships in egg masses, larvae and adults, respectively. The model slopes of the regression were greater than unity for all stages indicating aggregated spatial distribution. Values of the intercept were greater than zero for egg masses, larvae and adults indicating that the basic components of the population are groups of individuals. The highest density (>80%) of mating and feeding adults was found in the upper third of 1- to 2-mo-old seedlings, while most of the egg masses were found in the lower half of seedlings. In trees, >60% of the individuals of all stages were found in the lower third of the foliage canopy, while <10% were found in the upper third. Sampling adults was found to be easier and gave better density estimates of M. ochroptera population than egg masses and larvae. Therefore, sampling plans useful for population studies and decision-making in pest management were developed for adults.

Animals↗
PubMed2001

Two-dimensional versus three-dimensional cell counting: a practical perspective.

In recent years, it has been argued by some neuroanatomists that three-dimensional (3-D) counting approaches must be used in studies of neural systems, so that 'unbiased' counts of neurons can be obtained. By contrast, two-dimensional (2-D) cell-counting methods are said to be 'assumption-based' and to yield inaccurate results. Working from the premise that all scientific methodologies are assumption-based and suffer from inherent biases, the current review considers the relative strengths and weaknesses of 2-D versus 3-D counting approaches. This comparison is from the standpoint of predictive performance with respect to bias, variance and fidelity to the actual spatial arrangements of cells in the tissue under study. When these considerations are taken, together with the human resources that are required in using either methodology, 2-D methods offer more practical alternatives that might even provide more scientifically accurate estimates compared with their 3-D counterparts.

Animals↗
PubMed1997

Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration.

A continuous distribution approach, instead of the traditional mono- and multiexponential analysis, for determining quencher concentration in a heterogeneous system has been developed. A mathematical model of phosphorescence decay inside a volume with homogeneous concentration of phosphor and heterogeneous concentration of quencher was formulated to obtain pulse-response fitting functions for four different distributions of quencher concentration: rectangular, normal (Gaussian), gamma, and multimodal. The analysis was applied to parameter estimates of a heterogeneous distribution of oxygen tension (PO2) within a volume. Simulated phosphorescence decay data were randomly generated for different distributions and heterogeneity of PO2 inside the excitation/emission volume, consisting of 200 domains, and then fit with equations developed for the four models. Analysis using a monoexponential fit yielded a systematic error (underestimate) in mean PO2 that increased with the degree of heterogeneity. The fitting procedures based on the continuous distribution approach returned more accurate values for parameters of the generated PO2 distribution than did the monoexponential fit. The parameters of the fit (M = mean; sigma = standard deviation) were investigated as a function of signal-to-noise ratio (SNR = maximum signal amplitude/peak-to-peak noise). The best-fit parameter values were stable when SNR > or = 20. All four fitting models returned accurate values of M and sigma for different PO2 distributions. The ability of our procedures to resolve two different heterogeneous compartments was also demonstrated using a bimodal fitting model. An approximate scheme was formulated to allow calculation of the first moments of a spatial distribution of quencher without specifying the distribution. In addition, a procedure for the recovery of a histogram, representing the quencher concentration distribution, was developed and successfully tested.

Light↗
PubMed1995

Age-prevalence and household clustering of Strongyloides stercoralis infection in Jamaica.

The epidemiology of Strongyloides stercoralis was studied in families of clinical (reference) cases and their neighbours at endemic foci in Jamaica. Thirteen foci were studied based on the place of residence of a reference case. For each household of a reference case, the 4 most proximal neighbourhood households (spatial controls) were included in the study. Out of 312 persons contacted 244 were followed up using questionnaires, stool examination and serology. Prevalence of infection based on stool examination was 3.5% and on ELISA 24.2%. Prevalence increased with age but was not related to gender. Reference cases were significantly older than the general study population. The prevalence of infection based on both serology and stool examination was significantly higher in reference than in neighbouring households (the reference cases, themselves, were not included in the analysis). Furthermore, prevalence of infection was highest among persons who shared a bedroom with a reference case and decreased significantly with increasing spatial separation. This is indicative of close contact transmission which has not been previously shown for a geohelminth, but which is common among microparasites.

Adolescent↗
PubMed1992

Assessment of the spatial occurrence of childhood leukaemia mortality using standardized rate ratios with a simple linear Poisson model.

Reports of a suspected cluster of childhood leukaemia cases in West Central Phoenix have led to a number of epidemiological studies in the geographical area. We report here on a death certificate-based mortality study, which indicated an elevated rate ratio of 1.95 during 1966-1986, using the remainder of the Phoenix standard metropolitan statistical area (SMSA) as a comparison region. In the process of analysing the data from this study, a methodology for dealing with denominator variability in a standardized mortality ratio was developed using a simple linear Poisson model. This new approach is seen as being of general use in the analysis of standardized rate ratios (SRR), as well as being particularly appropriate for cluster investigations.

Adolescent↗
PubMedDate not supplied

[Cartography of epidemiologic data. The principal methods of making continuous data discrete and their importance in cartographic representation].

The cartographic representation of continuous quantitative data is often required in studies of the spatial distribution of health indicators. It imposes a succession of choices which directly affect the result obtained. The conversion of continuous data to discrete data is one of the most important steps in the development of epidemiological maps. This article presents the methods currently used to make data discrete, discusses the advantages and disadvantages of each method and assesses their appropriateness for various situations. As an example, and for comparison purposes, we mapped the same series of statistics (relative rates of avoidable male deaths, "associated with the health care system", for "employment zones" in France from 1988 to 1992), using each of the methods discussed.

Algorithms↗
PubMed1984

Geographic distribution of undocumented immigrants: estimates of undocumented aliens counted in the 1980 census by state.

"This article presents estimates of the number of undocumented aliens counted in the 1980 [U.S.] census for each state and the District of Columbia. The estimates, which indicate that 2.06 million undocumented aliens were counted in the 1980 census, are not based on individual records, but are aggregate estimates derived by a residual technique. The census count of aliens (modified somewhat to account for deficiencies in the data) is compared with estimates of the legally resident alien population based on data collected by the Immigration and Naturalization Service in January 1980." Estimates are provided "for each of the states for selected countries of birth and for age, sex, and period of entry categories.... The origins of the undocumented alien population [are described], as well as some of their demographic characteristics. Some of the implications of the numbers and distribution of undocumented aliens are also discussed." This paper was originally presented at the 1984 Annual Meeting of the Population Association of America (see Population Index, Vol. 50, No. 3, Fall 1984, p. 435).

Age Distribution↗