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[A case of psoriatic arthropathy complicated with spinal fracture and epidural hematoma].

A 78-year-old man with psoriatic arthropathy complicated with traumatic spinal fracture and epidural hematoma is reported. He had fallen down the stairs. On admission one hour after injury, he developed an incomplete C6 quadriparesis. CT revealed a C6-7 fracture and dislocation on sagittal reconstruction. MR imaging disclosed the compression of the spinal cord between the posterior margin of the vertebral body and an epidural hematoma. The patient had had the skin lesion, psoriasis vulgaris, for about 20 years and been previously treated for uveitis. Serological tests for rheumatoid factor and HLA B-27 were negative. Emergent laminectomy and evacuation of the epidural hematoma were carried out because of progressive neurological deterioration. Osteoporotic laminar bone and ossified yellow ligament were observed to have been fractured. Conservative therapy was selected for spinal instability. Although a respiratory complication occurred postoperatively, he was transferred to the rehabilitation facility in an improved neurological condition.

Accidental Falls↗

Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures.

The present study was performed to investigate the role of insulin-like growth factor I (IGF-I), IGF-binding protein-2 (IGFBP-2), and IGFBP-3 in age-dependent bone loss in postmenopausal Japanese women. One hundred and sixty-five Japanese women aged 43-88 years (mean age, 62) were enrolled in the cross-sectional study. Bone mineral density (BMD) was measured at the lumbar spine, femoral neck, and midradius by dual-energy X-ray absorptiometry or single-photon absorptiometry. Serum levels of IGF-I, IGFBP-2, and IGFBP-3 were measured by radioimmunoassay. BMD at all sites as well as serum levels of IGF-I and IGFBP-3 declined with age, while the serum IGFBP-2 level increased with age. Serum IGFBP-3 and -2 levels were positively and negatively correlated with the serum IGF-I level, respectively. Serum IGF-I and IGFBP-3 levels showed positive correlationship with BMD at any site, particularly at the midradius, while the serum IGFBP-2 level showed negative correlation with BMD. Multiple regression analyses showed age-independent positive correlation between the serum IGF-I level and BMD at all sites as well as age-independent positive correlation between the serum IGFBP-3 level and midradius BMD. The relationship between susceptibility to osteoporotic spinal fracture and serum IGF-I, IGFBP-3, or -2 levels was examined by decade to exclude the influence of aging. Serum levels of IGF-I and IGFBP-3 were significantly lower in subjects with spinal fractures than those without fractures at any decade. No significant difference of serum IGFBP-2 level was observed between subjects with and without fractures. The present findings suggest that IGF-I and IGFBP-3 are important to maintaining bone mass quantitatively as well as qualitatively, and that the determination of serum IGF-I and IGFBP-3 levels could be clinically useful to predict the severity of osteoporosis, particularly the risk of bone fracture associated with osteoporosis.

Absorptiometry, Photon↗

New trends in surgical stabilization of thoraco-lumbar spinal fractures with emphasis for sublaminar wiring.

Sixteen patients with unstable thoracic and lumbar spinal fractures and fracture-dislocations were treated surgically by contoured Harrington instrumentation and spinal fusion. Instrumentation was supplemented by sublaminar wires above and below the level of injury. Complications occurred in ten patients. All had solid fusion at follow-up. No loss of reduction occurred. Fourteen patients had a Fewett hyperextension brace post-operatively, and two had no immobilization.

Adult↗

Radiographic imaging in assessment of combined manubriosternal and spinal fracture.

Deceleration injuries combined with hyperflexion of the torso as seen in motor vehicle accidents can result in combination of sternal and spinal fractures. This type of injury is associated with abnormalities of the soft tissue structures of the thorax. This publication reviews a case report of a deceleration injury and emphasizes the imaging modalities necessary to evaluate this constellation of abnormalities.

Female↗

Functional outcomes after surgery for spinal fractures: return to work and activity.

OBJECT OF STUDY: The literature regarding surgical treatment's impact on patient function after spinal fracture is sparse. Some authors have speculated that operative injury--the dissection of paraspinous muscle tissue, damage to spinal motion segments, implantation of spinal devices--may impair functional recovery in spine trauma patients. Nonoperative care has produced satisfactory results in some hands, but results are difficult to reproduce, treatment is resource-intensive, and functional outcomes are poorly documented. This study reports return to work and functional recovery in a 5-year follow-up of severely injured patients treated with segmental spinal instrumentation. MATERIALS AND METHODS: Seventy consecutive patients treated with Cotrel Dubousset instrumentation for unstable thoracic, thoracolumbar, and lumbar spine fractures were followed-up. All had high-energy trauma and were admitted directly to a level 1 university trauma center; 38% were polytraumatized; and 56% had neurologic injuries. Indications for surgery included: (1) segmental instability; (2) incomplete or progressive neurologic injuries with residual spinal canal compromise; (3) concomitant injuries precluding cast treatment; and (4) polytrauma. Two patients died and six were lost to follow-up, leaving 62 (91%) for assessment at a mean 5-year follow-up (range 2-8 y). Clinical outcome has been reported. Functional recovery was assessed based on return to work, level of work, and level of daily activity. RESULTS: Despite the severity of spinal and concomitant injuries, 70% of patients returned to full-time work and another 8% were considered capable: 54% to their previous level of employment without restrictions and 16% to full-time, but lighter, jobs. Twenty-two percent were working part-time or not at all, and 8% were unemployed despite unrestricted functional status. Work status correlated directly with neurologic impairment (P < 0.00005) and was not related to level of injury, hardware failure, extent of surgical dissection, or construct pattern. Of patients with limitations, 18% were limited by pain and 27% by neurologic injury. CONCLUSION: Neurologic injury had a greater impact on functional outcome than any other variable. Patients limited by pain were more often impaired by residual radicular and neuropathic symptoms than by back pain. Impairment was not related to the extent of either the surgical incision or the instrumentation. Patients with persistent back pain generally had an identifiable and correctable mechanical problem-sagittal imbalance, pseudarthrosis, or persistent instability--as the underlying cause. Our series of trauma patients was predominantly young and male. Among this cohort, individual characteristics of occupation (often physical laborers and craftsmen) and judgment (criminal convictions and incarceration) may have restricted opportunities for re-employment in 40% of the entire study group.

Adolescent↗

Thoracolumbar spinal fractures: radiological results of transpedicular fixation combined with transpedicular cancellous bone graft and posterior fusion in 183 patients.

In internal posterior fixation of thoracolumbar fractures combined with transpedicular cancellous bone graft and posterior fusion of the intervertebral facet joints at the level of the destroyed end plate it is still uncertain as to whether significant vertebral body collapse and loss of correction of the regional angle (RA) and the intervertebral angle (IVA) occur (after removal of the implants). These questions were investigated in a retrospective study of 183 consecutive patients, 18-65 years old, with a spinal fracture between the 9th thoracic and the 5th lumbar vertebral body (inclusive), treated operatively between 1988 and 1996 (27% had objective neurological deficit, 37% had multiple injuries). According to the Comprehensive Classification, 128 type A, 32 type B and 21 type C fractures were identified preoperatively. Changes in the anterior wedge angle (AWA), the IVA and the RA were measured preoperatively, and within 1 month, 9 months and 24 months postoperatively. The effect of implant failure was also evaluated. The normality of the distribution was tested using the Kolmogorov-Smirnov (K-S) test. The one-sample runs test and the t-test were used to evaluate angle changes. Angles in patients with and without implant failure were compared using the unpaired t-test. Almost complete restoration of the AWA could be achieved during operation. Postoperative changes in AWA were either very small or not significant. The reduced vertebral body did not collapse after 9 months, when most of the patients (170) underwent removal of the implants, but significant changes in IVA were found after implant removal. Correction of the RA was statistically significant before implant removal, but the RA 2 years after surgery had become almost the same as the preoperative values. Changes at the level of the intervertebral space, occurring after implant removal, contributed to the loss in the RA. Broken pedicle screws (10.9% of the patients) resulted in significant changes in the AWA and RA before implant removal, but did not influence the IVA.

Adolescent↗

The relationship of trabecular and cortical bone mineral density to spinal fractures.

RATIONALE AND OBJECTIVES: The relationships between trabecular, cortical, or integral bone mineral densities (BMD) to spontaneous vertebral fractures was investigated. METHODS: In 360 Japanese women, ranging from 20 to 83 years of age, vertebral trabecular and cortical BMD were measured using quantitative computed tomography (QCT). Among 46 oophorectomized women, BMD was measured using QCT and dual-energy x-ray absorptiometry (DXA). RESULTS: For patients in their sixth and seventh decades, those with fractures could be differentiated from those without fractures by measuring their trabecular BMD using QCT. Cortical BMD of women with fractures and trabecular BMD more than 80 mg/mL was significantly lower than that of women without fractures and trabecular BMD less than 70 mg/mL. CONCLUSIONS: Trabecular BMD can be a good predictor of spinal fracture. Cortical BMD may be important in cases with decreased trabecular BMD.

Absorptiometry, Photon↗

The treatment of spinal fractures with Harrington compression rods and segmental sublaminar wiring. A dangerous combination.

The increasing use of more rigid internal fixation constructs for spinal fractures, especially in association with spinal cord injury, has led surgeons to combine sublaminar segmental wiring with Harrington instrumentation systems. Two clinical cases whose neurologic condition deteriorated postoperatively were shown to have sustained direct cord injury by the combination of Harrington compression rods with segmental sublaminar wiring. Myelographic and surgical evidence of hook protrusion into the spinal canal with direct cord injury is presented. Laboratory spine simulations duplicating the clinical situation did demonstrate that sublaminar wiring of the Harrington compression rod system caused the standard hooks to protrude dangerously into the spinal canal. Caution should be exercised not to combine Harrington compression rods with segmental sublaminar wiring.

Female↗

Spinal fractures complicating ankylosing spondylitis. A long-term followup study.

Twenty-two spinal fractures in 20 patients with chronic ankylosing spondylitis are reported. Nineteen fractures occurred in the cervical region. Fourteen of the fractures were caused by minor falls, 3 by falls down steps, 4 by motor vehicle accidents, and 1 by cardiopulmonary resuscitation. Long-term followup (mean 3.2 years) of 9 fractures diagnosed early and managed conservatively showed bony union of all fractures. No patient deteriorated neurologically and 3 patients made major recovery. Long-term followup is also reported on 6 patients in whom the diagnosis was delayed. The difficulties in diagnosis and management are discussed.

Aged↗

[Indications status and surgical treatment of spinal fractures. Attempt at a survey and determination of present status].

Indications for operative treatment of spinal fractures sometimes are difficult to work out. Undoubtedly deteriorating neurological deficits require decompression always combined with stabilization. Due to new classifications a severe instability of the fracture, an axis deviation more than 25 degrees and polytraumatized patients show up being an indication for operative treatment. A proper preoperative planning with use of X-rays and CT Scan as well as the knowledge of the kind and site of instability is mandatory. In cervical spine fractures anterior fusion seems to be the best method. In thoracic spine fractures dorsally attached plates give enough stability. In the thoraco-lumbar spine region and in the lumbar spine itself the internal fixator with dorsal instrumentation together with a transpedicular bone graft is preferred by the authors. Among 384 fractures of the spine 62 have been operated. Both kinds of treatment do not compete; they are complementary instead.

Bone Plates↗

Thoracic spinal fractures and aortic rupture: a significant and fatal association.

We analyzed the frequency of occurrence of traumatic aortic rupture (TAR) in patients with and without thoracic spinal fractures. Among 4,676 blunt chest trauma victims admitted to the hospital between 1972 and 1988, 148 (3.2%) suffered one or more thoracic vertebral fractures. There were 73 patients with one or more fractures of the first eight thoracic vertebrae (T1 to T8); of these 73, 4 also suffered TAR (5.5%). There were 4,603 patients without fractures of T1 to T8, and 64 of these patients also suffered TAR (1.4%). This difference was significant by the chi2 and Fisher exact tests, p = 0.00378 and p = 0.021003, respectively. Additionally, all 5 patients with TAR and thoracic vertebral fractures died. We conclude that patients with one or more fractures of T1 to T8 have a statistically significant increase in the incidence of TAR.

Adolescent↗

Spinal fracture through the neurocentral synchondrosis in battered children: a report of three cases.

STUDY DESIGN: Retrospective case series. OBJECTIVE: To report 3 cases of unusual spinal fracture through the neurocentral synchondrosis. SUMMARY OF BACKGROUND DATA: Traumatic lesions of the spine or spinal cord due to physical abuse are rare. We report 3 cases of vertebral fractures involving the neurocentral synchondrosis in battered children. METHODS: The medical data of the 3 cases were retrospectively reviewed. We discuss the pathomechanism and treatment strategies. RESULTS: In 2 cases, the vertebral body was displaced anteriorly and, in 1 case, posteriorly, all without neurologic compromise. The lateral radiographs showed vertebral displacement, but the diagnosis could be suspected on frontal views because of interpedicular distance widening. Treatment was nonoperative with bracing in 2 cases. In the third case, a posterior epiphysiodesis was done to avoid development of progressive kyphosis of the injured spine. One child treated nonoperatively died from other traumatic lesions associated with the physical abuse. In the 2 other cases, outcome was good with a well-balanced spine in 1 case and a moderate, well-tolerated kyphosis in the other case. CONCLUSIONS: Such spinal lesions are rare but could be conservatively treated in case of anterior vertebral displacement without vertebral endplate impairment. A posterior displacement of vertebral body could be responsible for a neurologic compromise.

Battered Child Syndrome↗

[Surgical treatment of old C2 spinal fracture with C2/C3 subluxation using an anterior retropharyngeal approach--case report].

A patient with an inverterate transpedicular fracture of atlas and C2/C3 subluxation, with stenosis of spinal canal by bone fragment, was operated using anterior retropharyngeal approach. Stabilization with interbody cage was performed. During follow up examination both clinical and radiological result was good. This surgical approach seems to be a comfortable approach to the upper cervical spine.

Cervical Atlas↗

[Spinal fractures in ankylosing spondylitis].

In the final stage of ankylosing spondylitis the spine will be completely fixed. With loss of mobility the patients suffering of ankylosing spondylitis are susceptible to spinal fractures. Predominantly the fractures occur in the lower part of the cervical spine, caused often by minor trauma. High fatality is at a 30% rate seen as severe consequence of these fractures. Conservative and operative treatment may be used. Severe fracture dislocation and progressive neurological deficiencies are recommended to be stabilized operatively. To avoid trauma of the spine in patients with ankylosing spondylitis preventive measures seem to be possible and should be employed.

Adult↗