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At least 109 records · Page 6Linked to original sources
PubMed1982

[Testicular neoplasms with massive tumor invasion. Consequences for diagnosis and therapy].

Cis-(diammine-dichloro-) platinum containing polychemotherapy combined with surgery has markedly improved the prognosis of cancer of the testis even in the metastatic stage. Important is a quickly obtained diagnosis. The histological staging can be rendered more precise by means of immunoperoxidase technique, the clinical staging with the help of tumor markers (alpha FP, beta hCG). Polychemotherapy is indicated in the case of seminoma in stage IV or with elevated beta hCG, teratoma in stage IIB-IV, chorion carcinoma in every stage, and should only be carried out in specialized oncological centers. Delayed and inconsequent treatment must be avoided. Only then more than 75% of patients treated with polychemotherapy can be freed from tumor, even up to 50% of those cases with unfavorable histology and extensive tumor stage.

Adult↗
PubMed1978

[Bilateral testicular neoplasms].

With 23 years an embryonal teratoma of the testicles and with 29 years a seminoma was treated by semicastration and post-irradiation or applications of cytostatics. In the two cases 10 or 12 years later seminomas of the other side appeared. Problems of the double-side simultaneous and successive affection are discussed, therapeutic consequences derived and the prognosis is entered. Apart from this the clinical and morphological signs of bilateral metastases of the testicles by a bronchial carcinoma are explained and discussed.

Adult↗
PubMed1994

[Laparoscopic lumboaortic retroperitoneal lymphadenectomy in testicular neoplasm].

Lumboaortic lymphadenectomy is a therapeutic alternative for patients with nonseminomatous testis tumors and its principal untoward effect is the loss of ejaculation. The anatomic knowledge of lymph node metastasis allows lower limit definition of aortic dissection, maintaining the diagnostic sensitivity and ejaculation. We report three patients with nonseminomatous testis tumors subjected to a reduced video-laparoscopic lumboaortic lymphadenectomy. An adequate amount of tissue was obtained in all and lymph node metastasis found in two. No complications occurred and patients were discharged 48 hours later. It is concluded that this technique is an alternative staging technique with low morbidity that allows a rapid patient discharge.

Adult↗
PubMed1978

[Therapy of testicular neoplasms].

It can be established that it is nowadays possible by means of an interdisciplinary therapy to achieve a full remission of more than 2 years in 80% of the malignant teratomas of stages I and II and in up to 40% of the teratomas of stage III, which possibly means a cure of the patient.

Bleomycin↗
PubMed1988

Pulmonary sarcoidosis associated with Leydig cell testicular neoplasm.

The first case of association between Leydig cell testicular tumor and sarcoidosis is reported. From a review of the literature, this is the ninth case of association between a testicular tumor and Besnier's disease. Lung biopsy should always be performed in patients with testicular cancer when retroperitoneal lymph node involvement cannot be demonstrated in order to avoid unnecessary antineoplastic chemotherapy.

Diagnosis, Differential↗
PubMed1990

Testicular neoplasms: seminoma.

From 1969 to 1984, 58 patients with a diagnosis of testicular seminoma were seen and treated at the University of Kansas Medical Center. The median age was 34 years (range of 20 to 62 years). The American Joint Committee on Cancer Staging System was followed: stage I (34 patients); stage II (6); stage III (8); and stage IV (10). Forty-two patients had typical seminoma, and 16 had anaplastic histology. Nine patients had elevated B subunit of human chorionic gonadotropin, and nine had a history of cryptorchidism. Fifty-six patients received radiation treatment, and seven received chemotherapy with or without radiation. The median follow-up was 7 years (range 3 to 16 years). The overall disease-free (absolute) survival according to stage was: stage I, 91% (100%); stage II, 66% (80%); stage III, 75% (85%); and stage IV, 50% (50%). There were no late complications. The survival for patients with anaplastic histology or with elevated B subunit of human chorionic gonadotropin was not significantly different from that of typical seminoma.

Adult↗
PubMed1976

[Results of radiotherapy of malignant testicular neoplasms].

It is very difficult to compare the therapeutic results of malignant testicular tumours because of the different histological classification systems, the uncertainty in the definition of the different stages, the error rate of the lymphography which amounts up to 35%, and the multitude of surgical, radiation, and chemotherapeutic methods. A histological classification and an exact determination of the stage is required as a condition of beginning a radiotherapy. The desirable focal dose for seminomas is between 4000 and 5000 rad, the maximum dose for teratomas is 6000 rad. For the stages T1-3N0 the iliac and the paraaortic lymph nodes are irradiated, for the stages T1-4N1-2 the interpleural space andthe supraclavicular region are included. For a group of 91 patients there was reached a five-year survival rate of 85,5% in case of seminomas and of 64% in case of teratomas.

Adult↗
PubMed1978

[Surgical treatment of malignant testicular neoplasms].

In a survey the different ways of surgical treatment of malign testicular tumors in men and boys are described in relation to their staging. As diagnostics and staging of these tumors depend on several diagnostic methods special regard is given to the significance of these methods and the frequency of misinterpretations.

Adult↗
PubMed1985

Testicular neoplasms in Hispanic brothers.

Two hispanic brothers developed nonconcordant testicular malignancies in an interval of 11 months. They represent the 36th report of familial testicular neoplasia. The problems deriving from poor patient compliance are documented.

Adult↗
PubMed1989

Intraoperative ultrasound in the conservative resection of testicular neoplasms.

In a series of approximately 400 patients investigated for oligospermia 4 had small testicular tumors demonstrated by high resolution real-time ultrasound. The lesions ranged in size from 3 to 6 mm., were clinically impalpable and were demonstrated on repeated sonograms. Exploration was done in all 4 patients with the aid of intraoperative high resolution ultrasound. This procedure allowed for conservative resection of the tumor with preservation of the testicle. The pathological diagnosis in all cases was benign Leydig cell tumor.

Adult↗
PubMed2005

[Testicular neoplasms. Evaluation of the experience during 25 years in a military hospital].

OBJECTIVES: The testicular tumors are frequent in the young adult, coinciding with the incorporation to the Military Service. The objective of our work is to evaluate the tumoral characteristic, its evolution with the time and the result of the treatments used in our center for this type of tumors. MATERIAL AND METHODS: We carried out a retrospective longitudinal study in a cohort of 98 patients with an average age of 28.6 years, subjected to orchiectomy for testicular tumor in our center between 1979 to 2004. In the study, we collected data referred to the age of the patients, the tumoral characteristic, the outcome of the treatment and the evolution of the tumor. RESULTS: In 61% of the cases, the affected testicle was the right (significant differences). The most common histologyc type was the non seminomatous germ cell tumors (NSGCT) (65.3%). Followed by the pure seminomas (27.6%), and non germinal cell tumors (NGC) (7.1%). The NSGCT was diagnosed to a average age (23.2 years) significantly smaller that the other two types. The stage I was the most frequent (58%). The seminomas presented a stage I in a significantly bigger frequency (80%) that the others tumors. The data picked up during the 25 years didn't show a significant variation regarding the tumoral characteristic. The survival análisis indicated that the tumoral characteristic with better pronostic regarding the probability of tumoral recurrences were the seminomas and the tumoral stages I and II. CONCLUSIONS: The non seminomatous germ cell tumors (NSGCT) are the most frequent testicular tumors in young adults. Most of the tumors are diagnosed in initial stages, and their pronostic is better in the case of the seminomas and in the stages I and II.

Adult↗