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Cigarette smoking and cognitive performance.

While some investigations into the relationship between smoking and cognitive performance have reported that smoking facilitates performance, other research has come to the opposite conclusion. A review of the literature suggests that this variance in results may be due to differences among studies in design (comparing smokers only with deprived smokers rather than with non-smokers) and also to differences in task demands. Therefore, performance of smokers having just smoked, matched smokers deprived for a brief period, and also non-smokers was contrasted on a series of tasks which ranged from repetitive and perceptually-bound tasks to complex, dynamic tasks dependent upon long-term memory. It was found that while cigarette smoking had no negative effect upon performance for simple perceptual tasks, smoking was found to exert measurable negative effects upon performance for more complex information processing tasks.

Adult

Auditory attention switching: a developmental study.

The developmental course of the ability to rapidly allocate attention was studied using a dichotic listening task with 8-year old, 11-year old and college age subjects. In this task, subjects were instructed to listen to one ear for predescribed targets and then were later signaled (on some trials) to switch their attention to the other ear. Reorientation was assessed by comparing the pattern of subjects' omission and intrusion errors on trials following a command to switch ears with the pattern of errors on no-switch trials. Older subjects were better able to reallocate their attention in accordance with task demands, with the greatest gains in performance occurring between ages 8 and 11. This developmental change appears to be generally continuous and quantitative in nature. Since successful performance of this task requires flexibility in subjects' ability to control their focus of attention, these results support the hypothesis that the basis of the developmental improvement in the ability to ignore irrelevant information is linked to the ability to use active attentional strategies.

Adolescent

The effects of videogame playing on the response selection processing of elderly adults.

Within an information processing framework, age-related declines in speeded responding are attributed to one or more stages of processing. It was the purpose of this experiment to demonstrate the potential reversibility of this decline in at least one processing stage, response selection. Two groups of elderly participants (57 to 83 years) were pretested on a two-choice reaction time (RT) task under two levels of spatial stimulus-response (S-R) compatibility, a task demand shown to affect response selection. Following the pretest, one group participated in 7 weeks of videogame play, whereas a second group did not. All participants were posttested on the same two-choice RT task. The results of the analysis of covariance revealed that those elderly individuals who played videogames were faster than the control participants under both levels of S-R compatibility. The effect of videogame play, however, was greater for low compatibility. These results are taken as support for a potential to improve response selection through videogame play.

Aged

The effects of EMG feedback training during problem solving: a case study.

The present case study investigated the effects of competing task demands on biofeedback training to reduce frontalis muscle tension. Baseline levels of frontalis muscle tension were recorded for relaxation and problem solving. The subject was trained to decrease muscle tension with biofeedback for the problem-solving task alone. The results indicated that EMG training during problem-solving was successfully accomplished. Frontalis muscle tension during relaxation baseline did not change as a result of reductions in muscle tension during problem-solving feedback training. This suggests that the decrease of muscle tension cannot be attributed to reductions in overall muscle tension levels. Instead, training was specific to the problem-solving feedback phases. Additionally, it was found that accuracy in problem-solving did not decline as a result of simultaneous feedback training. Thus EMG biofeedback training can be accomplished and exercised without disruption of ongoing mental activity.

Adult

The effects of spot treatments on performance in a driving simulator under sober and alcohol-dosed conditions.

Accident studies have identified nighttime conditions on rural roads as particular problems for alcohol-impaired drivers. Uneventful driving is hypothesized to result in progressive degradation of tracking performance and a reduced ability to handle the demands of hazardous locations, such as curves. To address these problems, four spot treatments (i.e. herringbone road marking, flashing beacon, chevron, and post delineator) were evaluated in a driving simulator. Twelve subjects drove a simulator under two conditions of task demand (with and without obstacles) and three levels of blood alcohol concentration (BAC): .00%, .07%, and .12%. The purpose of the study was to determine whether providing enhanced visual information about hazardous areas would improve the performance of subjects when sober or alcohol-dosed. Driver performance measures included speed, lateral position, and lateral acceleration on the approach and negotiation of horizontal curves of varying length and curvature. The results indicate that spot treatment effects were primarily curve-specific rather than uniform across curves. The effectiveness of spot treatments as alcohol countermeasures is discussed.

Accident Prevention

Cognitive impairments in depression.

Depressed patients perform poorly on memory tests. This may reflect a failure to employ encoding strategies that facilitate recall or a generalized inability to allocate cognitive effort to more difficult tasks. Inpatients with major depression or personality disorders and age- and IQ-matched normal controls were administered an automatic frequency of occurrence test and verbal paired associated recall and recognition memory tests. There was no difference in frequency judgments among the subject groups. Both depressed and personality disordered groups recalled and recognized fewer words than normal subjects, with the depressed subjects tending to recall and recognize the fewest words. There was a strong effect of task difficulty on memory performance but this effect was consistent across subject groups. These findings suggest that the poorer performance of depressed patients on memory tests reflect basic memory impairments rather than a general inability to allocate cognitive effort to more demanding tasks. However, these impairments may not be specific to depression but may reflect general effects of psychopathology on memory.

Adult

Electrodermal lability, errors, and reaction times: an examination of the motor impulsivity hypothesis.

Two studies were designed to investigate the effects of electrodermal lability on errors and reaction times (RTs). In Study 1 (n = 56) subjects performed an RT task that in different phases either required only fast responding or additionally discrimination and selection of one of two response alternatives according to specified rules that had to be stored in memory. Results showed that labiles (above the median of resting non-specific electrodermal responses) displayed significantly faster RTs when only speed was required. There were no differences between labiles and stabiles (below the median) in RTs and error rate when discriminations and response selections had to be made. In Study 2 (n = 52) task demands were reduced. Subjects were only required to discriminate between two events and to respond by releasing or retaining one key. Labiles displayed significantly faster RTs. There was furthermore a tendency among labiles to produce fewer False-Responses, i.e. releasing the key when it should be retained. Additional joint analyses of RT and error data revealed a tendency among labiles to perform the task more efficiently. Results are discussed in terms of motor impulsivity and information-processing accounts of electrodermal lability.

Adult

Effects of anxiety on inferential reasoning task performance.

Three experiments were conducted in which high anxiety and low anxiety subjects were required to construct inferences. In Experiment 1 there was no anxiety-related performance deficit when inferring a necessary anaphoric relation, a process argued to be automatic. Experiments 2 and 3 involved the verification of unnecessary inferences, a process argued to involve the utilization of the working memory system. In both Experiments 2 and 3 there was an anxiety-related performance deficit. The results are consistent with a working memory-oriented account of anxiety-related performance effects, as deficits were restricted to capacity-demanding tasks.

Anxiety

[Chronic diseases of the respiratory tract (proceedings)].

On account of their increasing social-medical importance chronic diseases of the respiratory tract demand systematic measures for prevention and combat. The size of the problem is described on the basis of the results of epidemiologic investigations. Issuing from the risk degrees of the cardio-respiratory insufficiency (obstruction, hypoxaemia, pulmonary hypertension) care groups are proposed. The combat against tobacco smoking (primary prevention) and long-term treatment of the chronic obstructive bronchitis (tertiary prevention) stand in the foreground of the measures. The solution of this task demands a close cooperation with the basic medical care.

Adult

The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm.

Regional cerebral blood flow, an index of local neuronal activity, was measured using positron emission tomography (PET) during the performance of the classic Stroop color/word task in eight healthy right-handed subjects. In the first condition of this paradigm, subjects name the color of the words presented on a video monitor. All the words are the color names congruent to the color presented (e.g., the noun "red" displayed in red color). In the second condition, subjects also name the color of the words presented on the monitor. However, during these trials all words are color names incongruent to the color presented (e.g., the noun "red" displayed in green color). The difference in brain activity between these two conditions (i.e., incongruent minus congruent) could reveal brain systems involved in the attentionally mediated resolution of the conflict between the habitual response of reading words vs. the task demands of naming the color of the words--i.e., the Stroop interference effect. The most robust responses occurred in the anterior cingulate cortex. Other responses noted were in the left premotor cortex, left postcentral cortex, left putamen, supplementary motor area, right superior temporal gyrus, and bilateral peristriate cortices. These data provide support for the role of the anterior cingulate cortex in attentional processing through the selection and recruitment of processing centers appropriate for task execution. Furthermore, the extensive distributed network of activated regions suggests that the Stroop interference effect cannot be explained simply in terms of stimulus encoding or response interference.

Adult

Cognitive behavioural strategies and anxiety in elite orienteers.

The primary purpose of this exploratory field study was to examine the use of cognitive behavioural strategies by highly skilled orienteers prior to and during competition. A secondary purpose of the study was to investigate whether differences in the level of qualification in orienteering is related to state anxiety. The subjects were divided into three classes with respect to their international and national records. The first two classes (A and B) were composed of international and national level athletes. The third class (C) included orienteers with unknown international records. Examination of the use of behavioural cognitive strategies during competition indicated that all orienteers reported a moderate use of mental imagery, above moderate use of inner talk and a focus of attention on present action rather than past or future. The other major findings were that prior to competition, superior orienteers reported use of higher self-efficacy, more positive outcome expectations and more task demand orientation than their less successful counterparts. Top orienteers coped more successfully with pre-competition anxiety by lowering their anxiety to a more moderate level prior to the actual performance.

Anxiety

Brain mapping in dysphonemic dyslexia: in resting and phonemic discrimination conditions.

Topographic mapping of EEG bands and alpha asymmetry were analyzed during resting conditions and an auditory phonemic discrimination task (APD) in carefully screened samples of 9.0- to 12-year-old control and dysphonemic-sequencing dyslexic children. The EEG was recorded over the entire scalp, with a linked ears reference. We found: (1) no differences between groups during resting conditions in any frequency band analyzed; (2) a left hemisphere alpha responsiveness in dyslexic children during the APD condition; and (3) a beta 2 decrease in the left posterior quadrant in dyslexics during the APD condition. We conclude that the lower alpha and beta 2 responsiveness may be due to a diminished cortical reactivity and may be related to intrinsic disorganization of the neural processors associated directly with the APD task demands, the alpha activity reflecting poor attention to an external stimuli source and the beta 2 decrease reflecting an unusual processing associated with the linguistic cognitive requirements.

Auditory Perception

Controlling multijoint motor behavior.

Much can be learned about the central nervous system from a study of motor coordination, but its true richness and complexity become evident only in a multiarticular system. Despite the intrinsic complexity of multiarticular actions, they offer an unparalleled opportunity to learn about the central nervous system in a quantitative and experimentally testable way. For example, the observation that unconstrained, unperturbed arm movements are coordinated in terms of hand motion shows that motor control is organized in a hierarchy of increasing levels of abstraction. These arm motions are organized as though a disembodied hand could be moved in space; the details of how this is to be achieved must then be supplied by a different level in the hierarchy. The essence of human behavior is its adaptability. Just as the true complexity of coordination is evident only in multiarticular actions, the sophistication and subtlety of adaptive behavior are evident only in dynamic, interactive tasks. A study of movement alone is not sufficient to understand this behavior. The dynamic response of the limbs becomes the overriding concern and must be controlled by the central nervous system. The dynamic response of a limb is usually associated with its posture, rather than its movement, but in a functional task such as the use of a tool, the postural dynamics are an integral part of the action. This perspective on motor behavior leads to some useful insights. Coordination is not a problem for movement alone; in a multiarticular system, even posture requires coordination and control. Muscles do not merely act reciprocally to generate forces about the joints; the net mechanical impedance of the limb may be controlled by synergistic activation of all muscles, including antagonists. Controlling dynamic behavior is a far more demanding task than controlling motion. Consequently, features of the neuromusculoskeletal system that appear to be redundant or unnecessary for movement control can play a functional role in controlling dynamic behavior. Polyarticular muscles contribute to the mechanical impedance in a unique way. Skeletal redundancies have a profound influence on all aspects of dynamic behavior, including the apparent inertia of the limbs. Redundancies are commonly perceived as a complicating factor in the control of motion, a problem that must be solved by the central nervous system. Rather than presenting a problem requiring solution, they may present a solution to a problem. Posture is not merely the outcome of a motor act; it is one of the important preparatory stages in the production of motor behavior.

Hand

Viewing distance and the sustained detection of high spatial frequency gratings.

Although conventional visual acuity tests measure the ability to resolve fine detail, many visual tasks demand prolonged detection. By evaluating the ability to maintain visual resolution, we observed that detection of stimuli subtending a small but constant visual angle depends on viewing distance and is probably determined by accommodative control. Detection was longest when viewing distance corresponded to the individual observer's accommodative resting, or tonus, position and fell off markedly for further distances. Since most visual assessment procedures involve a momentary detection criterion, they will not predict the ability to sustain accommodation and may thus overestimate visual resolution for prolonged viewing tasks.

Accommodation, Ocular

Job performance testing: an alternative to age discrimination.

The Age Discrimination in Employment Act has raised the issue of Bona Fide Occupational Qualifications for employment in the public safety sector. Complicating the issue is the number of lawsuits filed for violation of the Age Discrimination in Employment Act. Physical performance testing as an alternative to arbitrary age limitations is considered for physically demanding tasks in fire fighting, law enforcement, and the military. Tests with criterion-related validity are presented that are useful for screening new applicants and for periodic re-evaluation of incumbents. Extensive testing in our laboratory, in concert with the literature review, support the observation that age is a poor predictor of performance across the full range of employment years. It is concluded that individuals who are otherwise healthy, with proper attention to their lifestyles, can develop and maintain the necessary physiological profile to successfully execute the duties of physically demanding jobs well into their advancing years.

Adult

Human learning and memory.

There have been several notable recent trends in the area of learning and memory. Problems with the episodic/semantic distinction have become more apparent, and new efforts have been made (exemplar models, distributed-memory models) to represent general knowledge without assuming a separate semantic system. Less emphasis is being placed on stable, prestored prototypes and more emphasis on a flexible memory system that provides the basis for a multitude of categories or frames of reference, derived on the spot as tasks demand. There is increasing acceptance of the idea that mental models are constructed and stored in memory in addition to, rather than instead of, memorial representations that are more closely tied to perceptions. This gives rise to questions concerning the conditions that permit inferences to be drawn and mental models to be constructed, and to questions concerning the similarities and differences in the nature of the representations in memory of perceived and generated information and in their functions. There has also been a swing from interest in deliberate strategies to interest in automatic, unconscious (even mechanistic!) processes, reflecting an appreciation that certain situations (e.g. recognition, frequency judgements, savings in indirect tasks, aspects of skill acquisition, etc) seem not to depend much on the products of strategic, effortful or reflective processes. There is a lively interest in relations among memory measures and attempts to characterize memory representations and/or processes that could give rise to dissociations among measures. Whether the pattern of results reflects the operation of functional subsystems of memory and, if so, what the "modules" are is far from clear. This issue has been fueled by work with amnesics and has contributed to a revival of interaction between researchers studying learning and memory in humans and those studying learning and memory in animals. Thus, neuroscience rivals computer science as a source of interdisciplinary stimulation. Research on topics such as memory for spatial location, the relation between memory and affect, and autobiographical memory reminds us that general theories of memory based on studies of verbal materials alone are limited. Investigating how people remember complex natural events should provide us with a larger set of memory phenomena to explain and consequently insight into a wider range of memory principles or a deeper understanding of the ones we already accept (e.g. the role of repetition, encoding specificity), including their functional significance for human behavior.(ABSTRACT TRUNCATED AT 400 WORDS)

Affect

Alcohol-related efficiency deficits using an ecologically valid test.

This study investigated whether male and female alcoholics and controls differed in their ability to solve an ecologically valid measure of abstraction. Ninety-one alcoholics (39 females, 52 males) and 61 community controls (36 females, 26 males) completed a battery of abstraction tasks including a Piagetian-type task, the Plant Task. The Plant Task demands that subjects predict the outcome of an unseen plant given a specific treatment regime. No group differences in the ability to correctly predict the unseen plant's outcome were obtained. Alcoholics were significantly poorer than controls in isolating the relevant variable (chi 2 (1) = 8.24, p = 0.004). There were no sex differences in the ability to isolate the relevant variable. However, there was a sex effect in the number of irrelevant explanations (chi 2 (3) = 15.58, p = 0.001) with females producing more than males and female alcoholics more than any of the other three cells. These data suggest that (1) alcoholics may exhibit subtle abstraction deficits most readily observed in tasks examining process as opposed to final performance, (2) males and females differ in their response patterns regarding irrelevant material, and (3) further empirical study of the Plant Task may support its use in experimental and clinical settings.

Adult

Regional cerebral blood flow correlates of language processes in reading disability.

This series of studies tests the hypothesis of abnormal left hemisphere activation in reading-disabled subjects during language task performance. First, a left superotemporal focus of activation, as measured by regional cerebral blood flow, was found to be positively correlated with task accuracy in a group of 69 normal adults. Next, that left superotemporal activation was replicated in a second group of 83 adults whose childhood reading ability was known from standardized tests given in childhood. Finally, in that latter group, childhood reading ability was also found to be inversely correlated with focal activation in a more posterior, temporoparietal area of cortex. Adult reading outcome was statistically unrelated to this finding. The results are interpreted as suggesting a trait anomaly of left hemisphere cerebral activation in adults who were dyslexic as children and as providing an existence proof of individual differences in focal cortical activation sites during constant task demands.

Adolescent