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Ureteroscopic management of sepsis associated with ureteral stone impaction: is it still contraindicated?

INTRODUCTION: Retrograde decompression is generally not advocated for patients with sepsis owing to ureteral obstruction by stone impaction, and the initial treatment of choice is percutaneous nephrostomy (PCN). We report our experience with the treatment of urosepsis with retrograde ureteroscopy (URS) instead of PCN drainage. PATIENTS AND METHODS: Fifty-six consecutive patients diagnosed with ureteral stone-related sepsis received URS as primary treatment at our institution. Patients with uncontrollable sepsis underwent emergent URS and hemodynamically stable patients underwent elective URS within two days of diagnosis. RESULTS: URS was successful in 53 (94.6%) of the 56 patients. PCN was performed in the 3 cases of URS failure. Internal ureteral stenting was performed in 48 patients. Secondary procedures were performed in 10 (18.9%) patients. Twenty-six patients suffered from postoperative fever for an average of 1.6 days (range 1-4 days). There were no anesthesia-related morbidities, postoperative exacerbations of the clinical condition, or postoperative deaths. The median length of hospital stay was 7 days (range 3-94 days). CONCLUSION: PCN drainage is the standard treatment of sepsis associated with ureteral stone obstruction. However, our results show that URS can be safely and successfully performed by skilled endourologists in select clinical situations.

Adult↗

The LeVeen shunt: mechanisms of action, indications and contraindications to its use.

In summary, PVS has potentially a wide variety of indications. However, it is important to remember, as described in detail in this review, that this technically rather simple procedure may result in major complications. Thus, the clinician considering to employ PVS must be fully cognizant of its limitations so that it is wisely used and not abused.

Ascites↗

Are there schizophrenics for whom drugs may be unnecessary or contraindicated?

This study reports that there are schizophrenics who do relatively well long term without the routine or continuous use of antipsychotic medication. Specially selected young males undergoing an acute schizophrenic episode were followed, after hospitalization, for up to three years. While hospitalized they were assigned randomly to either placebo or chlorpromazine treatment. Many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer rehospitalizations and better overall function in the community than patients who were given chlorpromazine while in the hospital. Factors related to post-hospital outcome were good premorbid history and short-lived paranoid characteristics. Considerations which may have an effect on the successful management of acute schizophrenic patients not on medication are mentioned. The findings underline the need for further study of how to utilize antipsychotic medication more selectively in the treatment of schizophrenia.

Adolescent↗

Does old age contraindicate TURP.

OBJECTIVE: This investigation was performed to evaluate the prognostic role of high age as to survival after transurethral prostatic resection (TURP). MATERIAL AND METHODS: The study was retrospective, considering all men over the age of 80 years consecutively treated for lower urinary tract symptoms (LUTS). The material consisted of 249 patients who had TURP, 30 patients who were considered too ill for surgery and 18 who did not want treatment. Survival was compared to the background population. RESULTS: A significantly higher mortality was found initially if patients treated with TURP were compared to the age-matched background population. Twelve patients died within 30 days after operation. These patients suffered from severe preoperative comorbidity. Ninety-seven patients had chronic retention while only 17 had a catheter at discharge from the hospital. CONCLUSION: In conclusion, even very old men benefit significantly from a TURP provided they have been carefully selected.

Aged↗