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[Erysipeloid as an occupational disease of workers in shoe enterprises].

An outbreak of erysipeloid among the workers of a shoe factory is described. The spread of infection occurred due to contact with infected raw materials, which was confirmed by the isolation of Erysipelotrix rhusiopathiae from washings made from chrome and Russia leather supplied by different tanneries, as well as from casein glue. The raw materials could be additionally infected by rodents, in particular by common voles; the above-mentioned infective agent had been repeatedly isolated from these animals on the territory of this region. Leather was also infected in the process of soaking: the infective agent was isolated from the water of soaking baths. For the first time the routes of the spread of erysipeloid infection among shoe factory workers were bacteriologically confirmed. The recommended complex of sanitary, medical and antiepidemic measures led to the liquidation of the outbreak and thus proved to be effective. The authors draw the attention of epidemiologists, sanitary inspectors, occupational pathologists and heads of medical centers at shoe factories to the necessity of preventing the spread of occupational erysipeloid infection among the workers, as well as to the necessity for dermatologists, surgeons and infectionists, most frequently dealing with erysipeloid patients, to be correctly oriented in respect to this infection.

Adult↗

[Erysipeloid on the islands of the Ohhotsk Sea. 2. Landscape types of the natural foci of erysipeloid].

Cases of skin (skin-artericular) form of erysipeloid were recorded in the islands of the Sea of Okhotsk. The natural foci of the causative agent of this infection were polyhostal and polyvectoral in character. The causative agent of erysipeloid exists among the animals habitating on land and sea. Mass species of animals characteristic of the island landscape served as the sources of infection. Their four landscape types (mountaineous-taiga, of sea coast and rocks, anthropurgic settlement, and of water bodies--salt and freshwater) were preliminarily distinguished by the combination of biocenological, epidemiological, and epizootological peculiarities of natural erysipeloid foci.

Animals↗

Possible genetic variation in resistance of turkeys to erysipelas and fowl cholera.

Natural disease outbreaks of erysipelas and fowl cholera occurred in several lines of turkeys maintained for genetic studies. There were line differences in mortality during both outbreaks, suggesting that there is genetic variation in resistance to these diseases. A line developed by selection for increased egg production had a higher mortality rate from fowl cholera than did the randombred control line from which it was developed. Both the egg line and its control line had a lower mortality rate in the erysipelas outbreak than did a line selected for increased growth rate. Both diseases induced high mortality in a line selected for increased growth.

Animals↗

[Effect of specific vaccinal antigens and preparations on general resistance in growing experimental and domestic animals].

Studied was the effect of some viral and bacterial antigens as well as of a preparation obtained by Filatov's method (modified by the author) on the general resistance in growing laboratory and domestic animals. It was found that in infantile albino mice the best protection against challenge with Escherichia coli and Pasteurella avicida was provided through the treatment with a biostimulator and a killed culture of a strongly proteolytic, unidentified strain of the 'T3' bacterium. The vaccines against Newcastle disease, hog cholera+erysipelas, and anthrax were shown to have a weaker action. It was also established that the treatment of fattening calves and sucking pigs with a biostimulator raised the general resistance of animals. This was demonstrated with the higher resistance to diseases caused by occasionally pathogenic organisms, the better general state, and the higher weight gain. Sucking pigs treated twice with a biostimulator at an interval of twelve days showed 13.27 per cent lower mortality rate as compared with the controls.

Adjuvants, Immunologic↗

Pathology of experimental erysipelas in turkeys.

Gross and histopathologic lesions were studied in 10 Broad-Breasted White turkeys with acute erysipelas induced experimentally. The gross pathologic features of the disease conformed very closely with descriptions in the literature (7). Histopathologic evaluation was concentrated on the inoculation site (skin), proventriculus, ileocecal area of the intestine, liver, spleen, kidney, lung, and heart. In all organs examined the dominant histopathologic alteration was vascular damage as evidenced by: generalized congestion, edema, focal hemorrhage, disseminated fibrin thrombi, and numerous bacterial aggregates either within fibrin thrombi or engulfed by cells of the reticuloendothelial system. Degenerative changes or overt necrosis of parenchymal cells were evident in liver, spleen, and kidney. The cellular inflammatory component of acute lesions was minimal. Heterophil and mononuclear leukocytic infiltrates were observed in scarified skin and, in turkeys surviving several days, in livers and hearts.

Animals↗