[The role of hemodynamic changes in the pathogenesis of the dumping syndrome].
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Clinical symptomatology of early and late sequelae after resective surgery in peptic ulcer may be dramatic or insidious; insidious changes for instance may occur in the gastric mucosa or they may be due to chronic deficiency of elementary dietary components. Loss of pylorus function and duodenal-gastric reflux are the most important causes for these symptoms.
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Ten patients severely disabled by post-gastrectomy syndromes were allocated to two treatment groups. Those with predominant dumping received a 10-cm antiperistaltic jejunal interposition; those with predominant bile vomiting received a 20-cm isoperistaltic interposition. After follow-up for a minimum of 3 years, 6 patients remained virtually asymptomatic (Visick grades 1 and 2). There were 2 deaths from myocardial infarction, 6 months and 2 years after remedial surgery. One patient developed a stomal ulcer after successful treatment of dumping. Jejunal interposition appears to be a safe and relatively successful procedure. A short antiperistaltic loop is recommended for early dumping; for bile vomiting a longer isoperistaltic segment is a satisfactory alternative to Roux-en-Y conversion.
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The muscle weakness that frequently accompanies osteomalacia and rickets may arise from a variety of causes. Particularly in patients with muscle weakness, identification of the metabolic disorder is important, since effective treatment is often possible.
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