PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Absorbable Implants”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,099 records · Page 61Linked to original sources
PubMed1999

Running closure of clean and contaminated abdominal wounds using a synthetic monofilament absorbable looped suture.

The effectiveness of using an absorbable suture material for continuous closure of abdominal wounds, especially contaminated wounds, has not yet been determined. Thus, the present study was conducted to investigate the wound complications that developed following continuous closure of clean and contaminated abdominal wounds using polydioxanone (PDS), compared with those that developed following interrupted closure using braided silk. Running closure using PDS was performed in 152 patients (PDS group), while 280 patients who underwent interrupted closure using braided silk served as controls (SILK group). The occurrence rates of wound dehiscence, early wound infection, and incisional hernia did not differ significantly between the two groups; however, the incidence of late suture sinus formation in the PDS group (1.3%) was significantly lower than that in the SILK group (7.1%). Moreover, late suture sinus formation following PDS suturing healed within 1 week after percutaneous drainage alone without removal of suture strings, whereas late suture sinus following braided silk suturing took an average of 16 days to heal and required removal of the infected suture strings in all 20 patients. These findings indicate the potential usefulness of PDS as a suture material to achieve running closure of clean or contaminated abdominal wounds.

Abdominal Injuries↗
PubMed2006

[Arthroscopic Bankart operation using absorbable suture anchors].

OBJECTIVE: Arthroscopic refixation of the labrum-ligament complex at the glenoid. INDICATIONS: Posttraumatic anterior or anterior-inferior shoulder instability with Bankart or ALPSA lesion (anterior labral periosteal sleeve avulsion). CONTRAINDICATIONS: Atraumatic shoulder instability. Instabilities due to blunted or frayed degeneration of the labrum-ligament complex. HAGL lesion (humeral avulsion of the glenohumeral ligaments) with humeral detachment of the glenohumeral ligaments. Larger bony glenoid defects. SURGICAL TECHNIQUE: Mobilization of the labrum-ligament complex from the neck of the glenoid, superior tightening and refixation at the glenoid rim with the aid of absorbable suture anchors. POSTOPERATIVE MANAGEMENT: Immobilization of the affected arm for 4 weeks in an immobilization bandage with abduction pillows. Daily pendulum exercises. Active flexion up to 70 degrees and abduction up to 40 degrees, all in neutral or internal rotation. Avoidance of external rotation for a total of 6 weeks. RESULTS: From January 1999 to December 2001, 58 patients with a Bankart or ALPSA lesion were treated with arthroscopic shoulder stabilization using absorbable suture anchors and slowly absorbable braided sutures. 56 patients underwent a follow-up clinical examination after, on average, 31 months (24-48 months). None of these patients had suffered more than five shoulder dislocations before the operation (average 2.8). Of the intraoperative lesions, a plain Bankart lesion was present in twelve patients (21.4%), 44 patients had an ALPSA lesion (78.6%), of which one in two were combined with an SLAP 2 or SLAP 3 lesion (superior labrum from anterior to posterior). In the evaluation using the Rowe Score, there was an excellent result for 40 patients (71.4%), and a good result for twelve (21.4%). Four patients suffered a repeat dislocation and were therefore classified as poor results (7.2%).

Absorbable Implants↗
PubMed2002

[Technical refinements in planning and surgical therapy of pectus carinatum].

From 1998 to 2002 ten patients underwent surgical correction of pectus carinatum using a new diagnostic preoperative three-dimensional volume rendering mode computed tomography. Particularly the deformed rib cartilages can now also be visualized, which allows exact preoperative planning of the extent of cartilage resection and localization of required sternum osteotomies. This additional information results in a focused surgical approach and hence minimizes scars. As an additional innovation, resorbable plates and screws were used for refixation of the osteotomized parts of the sternum. For postoperative thorax immobilization and hypertrophic scar circumvention, a special keel chest brace was applied in all patients for 6-8 weeks. No complications occurred in any case, and all patients were very content with the aesthetic results achieved.

Absorbable Implants↗
PubMed2003

[Refixation of the meniscus with the SD meniscal staple: a comparative biomechanical study on cadaver knees].

GOAL: The failure load of the SD meniscal staple was compared with the 2-0 Etibond meniscus suture in a dynamic test without isolating the meniscus. METHODS: In eight knee joint pairs, a standardized lesion of the posterior part of the medial meniscus was repaired by either three staples (7 mm) or three 2-0 Etibond sutures. After resection of the cruciate ligaments and 15 degrees external rotation, 45 degrees flexion, and 70 kg of axial loading, a tibial translation was exerted on the knee joint. The test was documented on a way force diagram, demonstrating the failure of the device at a sudden load of force. RESULTS: The average load before failure of the meniscus staple was 591.2 N (540-690 N), that of the sutures 850 N (600-1350 N). We did not find any statistical correlation to age,weight, or height of the specimens. The suture migrated, but never ruptured. In two cases the suture caused a radial meniscus lesion. Failure of the staple was detachment of the inferior part in all cases, but no migration. CONCLUSION: This test is based on the dynamic forces of the knee joint on the meniscus. Our measurements show lower failure loads of the staple compared to those of the sutures, but compared to other tests a stable method of meniscus repair.

Absorbable Implants↗
PubMed2004

[Open Bankart shoulder stabilization using bioabsorbable staples. Technique and results].

In the supply of anterior unidirectional instability the open Bankart repair still represents the standard procedure. In a retrospective study 48 patients with an open repair were supplied with bioabsorbable staples and the result with 42 patients (88%) was postoperative clinically examined following 18-48 months. The middle number of dislocations of the affected shoulder was 8.8. After surgery the average Rowe Score amounted to 96.1 points. Reluxations arose with two patients. The middle external rotation of the affected side was reduced in comparison to the opposite side by 9.7 degrees. With the open supply of the unidirectional instability by absorbable staples (Suretac) an easy procedure of the open operation according to Bankart is available. Reproducible results occurred in our patients. Thus the advantages of arthroscopical operation technology with those of the open execution of capsular shift are combined applicable, providing both patient and operating surgeon a high security at a low rate of reluxation.

Absorbable Implants↗
PubMed2005

[Bioresorbable bone adhesives. Historical perspective and current status].

Bone adhesives are degraded to non-toxic products and resorbed after fulfilling their function in contact with living tissue. There has been a growing interest in the use of such adhesives in all fields of medicine in recent years. The wish of trauma surgeons and orthopaedic for alternatives to osteosynthesis is reflected in the development of a variety of surrogates of biological or synthetic origin. Despite a longstanding history of research in this field, a clinically applicable alternative in the field of bone gluing has not yet been found. This application has consistently failed because these adhesives were not tailored to the conditions met within the living organism. The following article is meant to provide an overview of the development, the state of the art, and today's knowledge of bone adhesives. In addition, it points out the tremendous progress in this area, made possible by the joint efforts of basic researchers and surgeons. The results of this collaboration show that in the future a successful reconstructive surgery using synthetic biomaterials will become feasible.

Absorbable Implants↗
PubMed2000

[Transplant fixation by anterior cruciate ligament reconstruction. Metal vs. bioabsorbable polyglyconate interference screw. A prospective randomized study of 40 patients].

To overcome some of the potential problems (e.g. hardware removal during revision surgery) of metal interference screws used for patellar tendon anterior cruciate ligament reconstruction, bioabsorbable screws have recently been introduced. Forty patients who underwent endoscopic ACL reconstruction using patella tendon autograft were included in the study, they were randomized intraoperatively to either Group A (femoral bone block fixation: polyglyconate screw; tibial: metal screw) or Group B (both bone blocks fixed with metal interference screws). The patients were evaluated clinically preoperatively as well as 6 weeks, 3 months 12 months and 24 months post op. Lysholm Score at 24 months was 98.1 +/- 2.3 for Group A and 97.7 +/- 3.0 for Group B. Tegner Score was 7.4 +/- 1.1 for Group A and 7.5 +/- 0.8 for Group B. Two years post op overall IKDC-Score for group A was 5.6% normal, 88.8% nearly normal and 5.6% abnormal. The result for group B was 11.1%, 77.8% and 11.1%, respectively. KT-1000 (at 89 N) at two years revealed a side to side difference of 1.5 +/- 0.3 mm (Group A) and 1.6 +/- 0.7 (Group B). The results of the two groups did not show significant differences at any stage of follow up. In our study polyglyconate interference screw fixation for patellar tendon grafts has not found to be associated with increased clinical complications. It provided equivalent fixation and clinical results compared to metal screws.

Absorbable Implants↗
PubMed2000

[Spontaneous fracture of the tibia after replacement of the anterior cruciate ligament with absorbable interference screws. A case report and review of the literature].

We report a granulomatous inflammatory reaction after administration of absorbable interference-fit screws for fixation of patellar-tendon-autograft in anterior-cruciate-ligament reconstruction, leading to spontaneous fracture of the tibia. Radiological evaluation demonstrated osteolytic lesions at the interference-fit screw insertion-site. Histological findings included a sterile inflammatory reaction and giant-cell formation.

Absorbable Implants↗
PubMed2005

[Transarterial chemoembolization of liver metastases of colorectal carcinoma using degradable starch microspheres (Spherex): personal investigations and review of the literature].

Since two decades transarterial chemoembolization (TACE) of liver metastases has been investigated in numerous studies. However, no standardized therapeutic procedure exists so far. The present study retrospectively investigated survival, response and side effects after TACE of liver metastases in 21 patients with colorectal cancer and results are compared with previous literature. A total of 68 TACE procedures were performed. A suspension of degradable starch microspheres (DSM, Spherex) and Mitomycin C was applied selectively into hepatic arteries via a transfemoral approach. DSM effect a temporary arterial occlusion. Follow-up studies were performed by contrast enhanced spiral computed tomography (CT). The median survival was 13.8 months. Therapeutic response (according to WHO) was observed only in three patients. The progression free interval was 5.8 months. Patients developed a postembolization-syndrome (abdominal pain, fever, nausea) and increased transaminases in 27-43% of all interventions. A gastric ulcer occurred after four, cholecystitis after two TACE. As already shown in most previous studies, regardless of the used agents, also this investigation underlines the moderate therapeutic effect of TACE on colorectal liver metastases. So far, no significant survival benefit has been shown in the literature and the response rates are rather limited. In general, complications of TACE seem to be rare, but should not to be underestimated. Compared to TACE with long or permanent arterial occlusion, postembolization syndrome seems to be less pronounced using DSM. As TACE is rather a palliative therapeutic approach, DSM therefore might be more suited. Further studies on TACE of liver metastases should focus on to the patients' quality of life.

Absorbable Implants↗
PubMed2004

[Tissue engineering of the urethra and ureter].

Congenital or acquired disorders of the urethra or ureter often require adequate tissue transfer for reconstruction. A variety of biomaterials have proved to be useful in the reconstruction of the urethra or ureter in animal models and meanwhile even clinically. Innovative tissues such as acellular matrices can be placed in the host and function as a scaffold to allow the natural process of tissue regeneration. Biodegradable scaffolds can also be used as cell transplantation vehicles for the reconstruction of urethral or ureteral tissue. One of the limitations of cell-based tissue engineering techniques however is the difficulty of growing genitourinary-associated cells in large quantities in primary cultures. It can be speculated that stem cell research might help to overcome this specific problem in the future.

Absorbable Implants↗
PubMed2004

[Tissue engineering of erectile nerves].

Dissection of the cavernous nerves eliminates spontaneous erections and may lead to irreversible erectile dysfunction due to degeneration of cavernous tissue. Novel procedures to reconstruct penile innervation include cavernous nerve interposition grafting and neurotrophic treatments to revitalize penile neural input, evaluated thus far in various preclinical models of cavernous nerve injury. Schwann cells crucially contribute to successful axonal regeneration by mechanical and paracrine mechanisms in the injured nerve, and Schwann cells seeded into guidance channels have been successfully employed to support regeneration in animal models of cavernous nerve injury. Gene therapy, tissue engineering, and reconstructive techniques have been combined to deliver neurotrophic factors and recover erectile function.

Absorbable Implants↗
PubMed2004

[Acellular matrix for functional reconstruction of the urogenital tract. Special form of "tissue engineering"?].

Organ substitution and reconstruction of the urogenital system still poses a problem regarding an adequate substitute. Usually non-organ-specific materials are used for reconstruction (bowl, buccal mucosa). This nonspecific tissue can cause side effects that result from the origin and the natural function. Different groups have shown that an acellular matrix graft in the urinary bladder and the urethra served as a scaffold for complete regeneration of all organ wall components and that this organ-specific regeneration simultaneously facilitates functional restitution. New approaches will presumably effect better regeneration after seeding the matrix with organ-specific cells (i.e., urothelial cells). Smaller studies on genital reconstructive surgery could show that vaginal substitution with an acellular matrix might be possible or that there could be a possible substitute for the tunica during surgical treatment of Peyronie's disease.

Absorbable Implants↗
PubMed2002

[Biomechanical properties of bioabsorbable cannulated screws for surgical fixation of dislocated epiphysiolysis capitis femoris].

Bioabsorbable materials are well suited for fixation of slipped capital femoral epiphysis (SCFE) as they are resorbable, compatible with magnetic resonance imaging, and well tolerated by the pediatric population. We compared cannulated 4.5-mm bioabsorbable screws made of self-reinforced polylevolactic acid (SR-PLLA) to cannulated 4.5-mm steel and titanium screws for their resistance to shear stress and ability to generate compression in a polyurethane foam model of SCFE fixation. The maximum shear stress resisted by the three screw types was similar (SR-PLLA 371 +/- 146, steel 442 +/- 43, titanium 470 +/- 91 MPa, NS). The maximum compression generated by both the SR-PLLA screw (68.5 +/- 3.3 N) and the steel screw (63.3 +/- 5.9 N) was greater than that for the titanium screw (3.0 +/- 1.4 N, p < 0.05). These data suggest that cannulated SR-PLLA screws have sufficient biomechanical strength to be used in the treatment of SCFE.

Absorbable Implants↗
PubMed2001

Secondary intra-articular dislocation of a broken bioabsorbable interference screw after anterior cruciate ligament reconstruction.

We report a case of intra-articular migration of the proximal part of a broken polylactic acid screw from the tibial site of anterior cruciate ligament-reconstruction with quadrupled semi-tendinosus tendon. Five months after initially successful ACL surgery the patient felt a sudden locking of the knee without another injury. MRI showed intra-articular migration of one-half of the polylactic acid screw, and standard radiographs a widening of the proximal tibial tunnel. At revision arthroscopy the broken part was easily removed. The patient had full recovery. This case demonstrates the problem of "bioscrew" breakage in ACL surgery.

Absorbable Implants↗
PubMed2003

Failure strength of bioabsorbable interference screws: effects of in vivo degradation for 12 weeks.

We investigated the effect of in vivo degradation for 6-12 weeks on the fixation strength of polylactide bioabsorbable interference screws. Ten bioabsorbable interference screws were used to fix the patellar tendon autograft in ten live sheep knees, which were equally divided into two groups and killed in the 6th or 12th week. The control group consisted of four cadaveric knees. Following the killing of the animals the screws were retrieved and reused to fix patellar tendon grafts in cadaveric sheep knees. Tendon pull-out tests were performed for the partially degraded screws, for the control group, and for the reused screws of the control group. Macroscopic and microscopic examinations of the 6- and 12-week specimens were performed. Tendons pulled-out with an average force of 357+/-30 N in the cadaveric control group on the first use and with 465+/-118 N on the second use. The partially degraded screws failed with a mean load of 399+/-119 N in the 6-week group, and 12-week screws at 447+/-72 N. No macroscopic sign of degradation was observed on the retrieved screws. Histological examination of the 6 week specimens showed necrotic changes in the tendon around screw contact areas. Healing with granulation tissue was present in the same area in the 12th week. Foreign body reaction or an excessive inflammatory reaction was not observed. In vivo degradation of poly- l-lactide interference screws for 12 weeks thus causes neither a loss in the fixation strength of the screws nor an obvious inflammatory reaction.

Absorbable Implants↗