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[Anesthesia simulators: benefits and limits of experience gained at several European university hospitals].

Simulation has become essential in all situations where reality was too risky, too expensive, difficult to manage or inaccessible. In anaesthesia, the low rate of accidents and incidents, as well as the necessity to assure patient's safety, limit education and training in crisis management. The progress in data processing allowed the development of realistic anaesthesia simulators, associating the usual environment of an operating room, and made possible the simulation of a wide range of events. Most clinical incidents, mishaps, or manipulation errors can be simulated. A video recording allows the focus of attention on human factors. We assessed simulators in three European University hospitals. In Brussels as in Leiden, simulation was mainly used for training in crisis management. In Basel, the complete operating room staff participated in sessions, including also surgical simulation and improvement of communication within the team was one of the main goals. Simulation is valuable for residents' training, as well as continuing medical education, in crisis management and a better understanding of human factors. It remains without risk for the patient, with video possibilities improving the repetition of selected cases. However, its use for evaluation seems to be premature, due to the absence of studies demonstrating the validity and reproducibility of the results gained with simulation. Beyond technical limits which are amended continuously, the development of simulation is hindered by the very high cost of equipment and instructors.

Anesthesia↗

Computer-based multimedia in plastic surgery education.

Rapid developments in communications networks (cellular telephone, direct-link satellite, and international high-speed computer nets) and the continued success of affordable powerful personal computers (desktop, laptop and soon "palmtop" devices) have set the stage for educational materials accessible by electronic means. Computer-based multimedia are sophisticated audiovisual teaching materials built from digitized illustrations, photographs, audio and video recordings viewed by display on a computer screen. The computer interface allows interactive access to information, and connectivity to other sources of information. Computer programmability allows presentation of a single collection of information at different levels of sophistication (the "patient", "medical student" or "surgeon trainee" level, for example), to appeal to different viewer needs. The information may be electronically updated or changed whenever appropriate. This desktop exhibit demonstrates multimedia plastic surgery teaching materials with full-fidelity digital sound, three-dimensional computer graphics, and "picture-in-picture" video capabilities that we have developed since 1989. We have used these materials at St. Louis University for patient informed consent, and the education of medical students and surgical trainees. We are excited that similar multimedia teaching materials are now becoming commercially available in other fields of medical education, attesting to broadening interest among educators and publishers.

Computer Graphics↗

Video analysis of the mechanisms for ankle injuries in football.

BACKGROUND: Although ankle sprains are frequent in football, little is known about their mechanisms. PURPOSE: To describe the injury mechanisms for ankle injuries in male elite football. STUDY DESIGN: Prospective cohort study. METHODS: Videotapes and injury information were collected for 313 of 409 matches from Norwegian and Icelandic elite football during the 1999 to 2000 seasons. Video recordings of incidents that resulted in ankle injuries were analyzed and cross-referenced with injury reports from the team medical staff. RESULTS: A total 46 acute ankle injuries were reported to have occurred, that is, 4.5 injuries per 1000 match hours. Of these, 26 (57%) were identified on the videotapes. Two mechanisms thought to be specific to football were found: 1) player-to-player contact with impact by an opponent on the medial aspect of the leg just before or at foot strike, resulting in a laterally directed force causing the player to land with the ankle in a vulnerable, inverted position; and 2) forced plantar flexion where the injured player hit the opponent's foot when attempting to shoot or clear the ball. CONCLUSIONS: Systematic video analysis provides detailed information on the mechanisms for ankle injuries in football-for lateral ligament sprains and for the condition dubbed "footballer's ankle."

Adult↗

Thoracoscopy: present diagnostic and therapeutic indications.

Thoracoscopy is increasingly being used for diagnosis and treatment of pleuropulmonary disease. The recent revival was made possible by the tremendous advances in endoscopic technology. The main requirements for diagnostic purposes are rigid telescopes and forceps, and for interventional thoracoscopy scissors, staplers and a video recorder. The procedure can be performed either under local or general anaesthesia, with or without double lumen intubation, after inducing an artificial pneumothorax. At the end of the procedure, a chest tube should always be inserted, even if only for a few minutes until the lung re-expands. Main diagnostic indications are pleural effusions, pneumothorax and diffuse lung disease. Main therapeutic indications are pleurodesis by talcage in effusion and pneumothorax and a variety of diseases of the lung, the pleura and the mediastinum, where thoracotomy may be replaced by video-assisted thoracoscopy. The well-known indications of the past remain a domain of pneumologists, whereas minimal invasive thoracotomy is the task of thoracic surgeons. For some indications no sharp line has to be drawn, provided the facilities and skills are present, including those for the management of complications.

Humans↗

Use of evidence in the process of practice change in a clinical team: a study-forming part of the Autocontrol Project.

The Autocontrol Project is concerned with the accessing, processing and communication of high quality information so that a clinical team can make and implement decisions for practice change, and then evaluate if improvement has been achieved. High quality information is used as evidence for change. In this study, we have evaluated how evidence is used by a clinical team to explain an identified problem of inappropriate use of blood gas tests. In an experimental study of the Surgical Intensive Care Unit, video recordings of team meetings of nurses and doctors were undertaken, structured according to a problem-based format. Evidence of current practice patterns derived from the hospital information system, as well as the results of a questionnaire to the unit's staff about knowledge and use of blood gas measurements, were supplied to the participants beforehand. At the second meeting, the output of the first meetings and a summarised analysis of pertinent literature were made available. This second meeting was required to finalise the list of causes of inappropriate blood gas use and propose pragmatic strategies for practice change. The video data of the meetings were coded to analyse the use of evidence, the categories of causes, issues and solutions proposed, and the quality of team interaction. The results indicate that in order to achieve consensus, the team used different types of evidence, including objective evidence of practice patterns, personal experience about direct and indirect organisational influences, and literature-based research evidence of best practice. Furthermore, group dynamics were favoured by the problem-based meeting structure, and a high level of cognitive critiquing between team members was observed. This research suggests that a combination of approaches involving identification of both operational factors (e.g. appropriate access to different types of evidence and meeting structure) and cognitive and behavioural approaches (e.g. ensuring expression of different viewpoints) is needed to support strategic decision-making for practice change in a clinical unit. This combined approach should favourably influence the provision of an effective and efficient evidence support environment for the clinical team.

Blood Gas Analysis↗

Website navigation and surgical education.

We evaluated the way in which medical students interacted with a surgical education Website. Ten medical students on their paediatric surgery rotation were asked to study online a chapter on intussusception in young children, for a period of 1 h. The computer was connected by video link to a video-recorder that recorded their navigation movements, i.e. navigation time, time spent in front of each page, stepwise, progressive exploration of the surgical contents, and use of interactive links. The students were asked to complete a questionnaire to identify their overall competency in computers and Internet navigation capabilities. The mean time spent viewing the entire Website was 48 min (range 31-63) and the mean time spent on the assigned chapter was 38 min (range 8-53). Each page out of 14 within the chapter was visited a mean of 1.8 times (range 0-10). Access to video selections occurred after a mean of 10 min after beginning the session. A connection was made to the video a mean of 2.3 times per session. The mean time spent viewing video footage was 9 min (24% of the time spent viewing the chapter). The questionnaire results showed that few students regularly accessed the Internet for educational purposes.

Attitude to Computers↗

An automatic procedure for evaluation of single cell motility.

BACKGROUND: Cell motility is vital in many physiological and pathological processes, such as embryogenesis, inflammation, wound healing, and metastasis. However, the time-consuming step in the evaluation of individual cell motility is the analysis of hundreds of recorded images of cell cultures in general consisting of retrieving images, one at a time, and marking the positions of individual cells by a computer mouse. Therefore, the aim of the present study was to develop a novel automatic procedure for the evaluation of cell motility. MATERIALS AND METHODS: The procedure was tested on fibroblasts and glioma and adenocarcinoma cells engineered to express the green fluorescent protein by either transient transfection or adenovirus transduction, allowing automatic recognition of cell coordinates on retrieved images. RESULTS: The effects of serum growth factors, teratogenic compounds, and overexpression of transcription factors on the motile behavior of cultured cells were determined. Cell motility was estimated by both manual and automatic marking of cell position and subsequently motility parameters were computed. The results obtained by the two procedures were found to correlate significantly. CONCLUSIONS: We developed a procedure allowing automatic video recording of sparsely seeded cells transfected with a plasmid or tranduced with a recombinant virus expressing the enhanced green fluorescent protein (EGFP).

Adenocarcinoma↗

[Experimental comparative study of 3 systems of osteosynthesis for proximal humeral fractures. Preliminary study of the mechanical properties of conserved trabecular bone].

PURPOSE OF THE STUDY: We have compared three systems for osteosynthesis of proximal humeral fractures on a four-fragment fracture model: Plate with tuberosity screwing (P), Kirschner wires with bone sutures (K) and an original implant, the "bilboquet" (Stryker) (B), composed of a hook for the head supported on a diaphyseal stem. MATERIAL AND METHODS: Because of the unavailability of fresh human material, we have turned to embalmed bones after having shown, on cancellous femoral head bone, the little influence of our method Vs freezing conservation. Settings were tested in compression. We measured their mechanical resistance judged on the ultimate strength and on the slope (displacement/load), to this limit. We similarly analyzed by video recording displacement of the different fragments according to four components (head slipping, its lateral displacement, its see-saw and the separation of tuberosities), to show the weak points of the three systems. RESULTS AND DISCUSSION: K was more deformable (p < 0.001) that P and B (average slopes in mm/100N to 0.67 for K, 0.42 for P and 0.43 for B). The ultimate strength differed but not significantly (average values in Newton to 1223 for K, 1601 for P and 1721 for B). We also showed for the three techniques, the significant correlation between slopes and bony densities. Video analysis showed that P opposed lateral displacement of the head and separation of tuberosities better, the resistance to slipping and see-saw seems to be improvable by greater divergence of screws or a modification of the plate (mini canon). B opposed slipping and see-saw better but its weak point was the risk of articular break-in of the hook, by defect of resistance to lateral displacement, that for us could be limited by a less peripheral position of teeth or a modification of their form. K is indeed the least effective of the four components but we think that it would be improvable by using, for example, a centro-medullary technique, allowing an internal cortical support.

Bone Density↗

Conflict resolution in 5-year-old boys: does postconflict affiliative behaviour have a reconciliatory role?

In nonhuman primates, affiliative behaviours, such as social grooming and various forms of body contact, become more frequent after an aggressive interaction. Since such behaviours lead to a decrease in postconflict aggressive behaviour and displacement activities and to increased social tolerance, they have been labelled reconciliatory. We videofilmed sessions of free play in daycare centres in Stockholm and investigated whether affiliative behaviours used by 5-year-old boys in the postconflict period had a similar reconciliatory function. For 219 conflicts in 21 h 40 min of observation we recorded postconflict affiliative/prosocial, aggressive and displacement behaviours. When affiliative behaviours were shown and accepted by the opponent, aggressive and displacement behaviours decreased and play was promoted. These behaviours thus serve a function similar to reconciliatory behaviour in nonhuman primates and we think it is applicable to call accepted affiliative behaviours in postconflict periods of preschool children reconciliatory. However, conflicts were often polyadic and nonconflict periods consisted of intense play with a rich exchange of affiliative behaviours. These factors were limitations to the postconflict/matched-control method traditionally used in primatological research to document reconciliatory behaviour. We suggest that for preschool children, video recordings and an analysis and description of postconflict affiliative, aggressive and displacement behaviours can be used instead. Copyright 1999 The Association for the Study of Animal Behaviour.

Journal Article↗

Algorithms to determine event timing during normal walking using kinematic data.

Algorithms to predict heelstrike and toeoff times during normal walking using only kinematic data are presented. The accuracy of these methods was compared with the results obtained using synchronized force platform recordings of two subjects walking at a variety of speeds for a total of 12 trials. Using a 60Hz data collection system, the absolute value errors (AVE) in predicting heelstrike averaged 4.7ms, while the AVE in predicting toeoff times averaged 5.6ms. True average errors (negative for an early prediction) were +1.2ms for both heelstrike and toeoff, indicating that no systematic errors occurred. It was concluded that the proposed algorithms provide an easy and reliable method of determining event times during walking when kinematic data are collected, with a considerable improvement in resolution over visual inspection of video records, and could be utilized in conjunction with any 2-D or 3-D kinematic data collection system.

Acceleration↗

Video information combined with individualized information sessions: Effects upon emotional well-being following coronary artery bypass surgery--A randomized trial.

OBJECTIVE: To test the efficacy of an information intervention upon emotional recovery following coronary artery bypass surgery. METHODS: Randomized trial. Video information was combined with individualized information sessions carried out by nurses at admission and at discharge from the hospital. The video was shown pre-operatively and again during the session at admission. Patients were helped to express their questions and worries and congruent information and support was provided. Control group patients received standardized information and no video. Recordings were made at baseline, discharge from hospital and during a 2 years follow-up period. RESULTS: One hundred and nine patients were randomized to the intervention or the control groups. A MANOVA was used to test of the variance of the outcome variables at each time point. At discharge intervention patients reported less anxiety (p = 0.046) and better subjective health (p = 0.005). They reported better subjective health during the whole follow-up period (0.040 > or = p > or = 0.000), less anxiety up to 1 year (0.042 > or = p > or = 0.004), and less depression from 6 months to 2 years following discharge (0.023 > or = p > or = 0.004). CONCLUSION: The effects of the intervention probably relate to the combined use of the video and patient centered information sessions. PRACTICE IMPLICATIONS: The intervention can easily be implemented in clinical practice and nurses strongly identified with its principles.

Anxiety↗

Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion.

Time lapse video recordings of cultured adult human and guinea pig spiral ganglion (hSG and gpSG) show that mitogen responsive progenitor/stem cells develop in the form of spheres that proliferate and differentiate into mature neurons and glia cells. Neurospheres, cultured with EGF and bFGF showed expression of nestin and incorporation of 5'-Bromo-2-deoxyuridine (BrdU). Newly formed BrdU labelled cells were positive for beta-tubulin, and also for GFAP demonstrating that neuronal cells were derived from a dividing population of progenitor cells. Dissociated spheres cultured either with glia cell line-derived neurotrophic factor (GDNF) or brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), induced differentiation of the progenitor cells. Video microscopy showed that neurons develop from subcultured spheres maintained for up to four weeks. Neurons showed fasciculation and migration with a speed of 10-30 microm/h, and some cells had up to 6 mm long neurites coexpressing TrkB and TrkC receptors. Precise dissection suggests that the neurons formed are cochlea-specific. The results suggest that the mammalian auditory nerve has the capability for self-renewal and replacement. Transplantation of progenitor cells together with established means to induce neural differentiation and fiber growth may facilitate strategies for better repair and treatment of auditory neuronal damage.

Adult↗

Frequency of open windows in motor vehicles under varying temperature conditions: a videotape survey in Central North Carolina during 2001.

Air pollution exposures in the motor vehicle cabin are significantly affected by air exchange rate, a function of vehicle speed, window position, vent status, fan speed, and air conditioning use. A pilot study conducted in Houston, Texas, during September 2000 demonstrated that useful information concerning the position of windows, sunroofs, and convertible tops as a function of temperature and vehicle speed could be obtained through the use of video recorders. To obtain similar data representing a wide range of temperature and traffic conditions, a follow-up study was conducted in and around Chapel Hill, North Carolina at five sites representing a central business district, an arterial road, a low-income commercial district, an interstate highway, and a rural road. Each site permitted an elevated view of vehicles as they proceeded through a turn, thereby exposing all windows to the stationary camcorder. A total of 32 videotaping sessions were conducted between February and October 2001, in which temperature varied from 41 degrees F to 93 degrees F and average vehicle speed varied from 21 to 77 mph. The resulting video tapes were processed to create a vehicle-specific database that included site location, date, time, vehicle type, vehicle color, vehicle age, window configuration, number of windows in each of three position categories (fully open, partially open, and closed), meteorological factors, and vehicle speed. Of the 4715 vehicles included in the database, 1905 (40.4%) were labeled as "open," indicating a window, sunroof, or convertible top was fully or partially open. Stepwise linear regression analyses indicated that "open" window status was affected by wind speed, relative humidity, vehicle speed, cloud cover, apparent temperature, day of week, time of day, vehicle type, vehicle age, vehicle color, number of windows, sunroofs, location, and air quality season. Open windows tended to occur less frequently when relative humidity was high, apparent temperature (a parameter incorporating wind chill and heat index) was below 50 degrees F, or the vehicle was relatively new. Although the effects of the identified parameters were relatively weak, they are statistically significant and should be considered by researchers attempting to model vehicle air exchange rates.

Air Movements↗

Differential phasic modulation of short and long latency afferent sensory transmission to single neurons in the ventroposterolateral thalamus in behaving rats.

Single neurons were recorded in the forepaw area of the ventroposterolateral (VPL) thalamus of awake rats during rest and running behaviors. Locomotor step cycle dependent changes of the transmission of the short (4.0 +/- 0.1-10.1 +/- 0.3 ms, SEURs) and the long (10.2 +/- 0.2-26.0 +/- 2.1 ms, LEURs) latency somatic sensory responses were tested by generating post-stimulus time histograms of these neurons' responses to stimulation through electrodes chronically implanted under the skin of the forepaw. The magnitudes of firing during these responses were measured and normalized as percent increases over background firing. Times of footfall were determined through frame-by-frame analyses of video recordings and peri-footfall histograms were generated to differentiate a total of 40 VPL thalamic neurons into two types, footfall responsive (n = 21) and unresponsive (n = 19) neurons. Perifootfall gating patterns were determined for both types of cells. The SEURs and the LEURs showed significantly different phasic sensory modulation patterns across the locomotor step cycle. Major difference of the sensory modulations between footfall responsive and footfall unresponsive cells was noted during swing phase of the locomotor step cycle. In footfall responsive cells, the SEURs were suppressed most strongly just after footfall, while the LEURs were tonically suppressed during late stance and swing phases. The SEURs were disinhibited during the swing phase, while the LEURs were disinhibited during the middle stance phase. In footfall unresponsive cells, the LEURs were suppressed more strongly around footfall event than the SEURs were.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

An automated method for analysis of flow characteristics of circulating particles from in vivo video microscopy.

The behavior of white and red blood cells, platelets, and circulating injected particles is one of the most studied areas of physiology. Most methods used to analyze the circulatory patterns of cells are time consuming. We describe a system named CellTrack, designed for fully automated tracking of circulating cells and micro-particles and retrieval of their behavioral characteristics. The task of automated blood cell tracking in vessels from in vivo video is particularly challenging because of the blood cells' nonrigid shapes, the instability inherent in in vivo videos, the abundance of moving objects and their frequent superposition. To tackle this, the CellTrack system operates on two levels: first, a global processing module extracts vessel borders and center lines based on color and temporal patterns. This enables the computation of the approximate direction of the blood flow in each vessel. Second, a local processing module extracts the locations and velocities of circulating cells. This is performed by artificial neural network classifiers that are designed to detect specific types of blood cells and micro-particles. The motion correspondence problem is then resolved by a novel algorithm that incorporates both the local and the global information. The system has been tested on a series of in vivo color video recordings of rat mesentery. Our results show that the synergy between the global and local information enables CellTrack to overcome many of the difficulties inherent in tracking methods that rely solely on local information. A comparison was made between manual measurements and the automatically extracted measurements of leukocytes and fluorescent microspheres circulatory velocities. This comparison revealed an accuracy of 97%. CellTrack also enabled a much larger volume of sampling in a fraction of time compared to the manual measurements. All these results suggest that our method can in fact constitute a reliable replacement for manual extraction of blood flow characteristics from in vivo videos.

Algorithms↗

Assessing mobility and locomotor coordination after stroke with the rise-to-walk task.

INTRODUCTION: To assess mobility and locomotor coordination after stroke with the rise-to-walk task (RTW) and to examine the construct and concurrent validity of this task. METHODS: Nineteen subjects who had sustained a stroke and 19 healthy subjects performed the RTW task. The performance was recorded simultaneously with 2 clinical methods and 1 instrumented method. The RTW duration and fluidity of the motor strategy (fluid or nonfluid) were compared between groups and between methods. The relationship between RTW duration and 3 locomotor-related disability tests, as well as 1 motor impairment test, was studied. RESULTS: The subjects with stroke took 65% more time to complete the RTW task, and 16/19 separated the tasks of rising and walking (nonfluid strategy). Measures of the RTW duration with clinical methods were strongly correlated (r = 0.84 to 0.98) to those from the instrumented method, and the motor strategy was successfully assessed from video records. The duration was moderately correlated to scores from other locomotor-related tests, but not to the motor impairment test. DISCUSSION: The assessment of mobility and locomotor coordination with the RTW task indicate that both outcomes are impaired after stroke and that clinical methods provide a valid measurement of the task.

Adult↗

Responses of juvenile bonnet macaques to social stimuli presented through color videotapes.

Twelve juvenile bonnet macaques (Macaca radiata), 6 males and 6 females, were presented with color videotape recordings of 3 types of social stimuli. The stimulus animals, all unfamiliar adult conspecifics, consisted of a passive female, a passive male, and a threatening male. Subjects were observed in the presence of their mother and 1 other juvenile-mother dyad. The juveniles showed the highest scores for contact with mother when presented with the threatening male stimulus. Similarly, subjects lipsmacked significantly more to the male threatening male stimulus than to either the passive male or female. The female stimulus was approached significantly more than either the passive or threatening male. Results suggest that juvenile macaques will respond to social stimuli presented through color video recordings in a socially appropriate manner. This technique provides a new tool in the investigation of social perception in nonhuman primates.

Animals↗

Physical and perceptual-cognitive demands of top-class refereeing in association football.

The aim of this study was to examine the physical and perceptual-cognitive demands imposed on UEFA top-class referees and assistant referees during the final round of the Euro 2000 Championship. To investigate the physical workload, the heart rates during matches were monitored by short-range radio telemetry and translated to different workloads expressed as a percentage of maximal heart rate. For measurement of the perceptual-cognitive workload, video-recordings of games were used to obtain the average number of observable decisions taken by a referee. On average, referees and assistant referees performed the matches at 85 +/- 5% and 77 +/- 7% of their maximal heart rate, respectively. Over the 31 games, the mean number of observable decisions was 137 (range 104-162), 64% of which were based on communication with the assistant referees and/or the fourth official. To optimize the physical preparation of top-class match officials, the results of this study support the application of intensive and intermittent training sessions, which should place priority on high-intensity aerobic stimuli. In addition, video training is discussed as an additional method for improving match officials' decision making.

Adult↗