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[Anatomy and embriology of double outlet right ventricle (author's transl)].

After formulating the definition of double outlet right ventricle (DORV) as the persistence origin of the trunco-conal structures from the right ventricle, 64 autopsy cases meeting this definition were reviewed. A wide spectrum of anatomic variations of DORV were found. A classification is proposed based upon the type of relationship between the great vessels and upon the presence and type of ventricular septal defect. Twenty-five cases had normally crossed great arteries (13 of which had pulmonic stenosis), nine cases had transposed vessels and 23 cases had a double muscular conus and a side-by-side arrangement of the great vessels in the frontal view, a relationship called "partial distortion" or atypical transposition. Seven cases had absent trunco-conal septum (common truncus). Only one case had intact ventricular septum. Anterior ventricular septal defect was found only in cases with partial distortion or common truncus. Angiographic and surgical correlations are presented. Because of their great heterogeneity, the need for detailed description of the anatomy of the individual case of DORV is emphasized.

Heart↗

Abnormal vasomotor function of the epicardial coronary arteries in children five to eight years after arterial switch operation: an angiographic and intracoronary Doppler flow wire study.

OBJECTIVES: This study sought to test the vasoreactivity of the translocated coronary arteries after arterial switch operation (ASO) using quantitative angiographic analysis and intracoronary Doppler flow wire velocimetry. BACKGROUND: Late coronary artery events occur in 3% to 8% of patients after the ASO. Previous studies of coronary flow reserve have yielded disparate results. METHODS: Nineteen children previously underwent ASO (13 boys, age 5.4 +/- 3.2 years, weight 22.3 +/- 10.6 kg), and six control patients were enrolled in the study. Each patient underwent quantitative angiographic assessment of the epicardial coronary arteries before and after administration of nitroglycerin and coronary blood flow volume assessment before and after administration of adenosine and acetylcholine. The results were compared between groups. RESULTS: Epicardial coronary artery dilation in response to intracoronary nitroglycerin was significantly less in the ASO group than in the control group (left anterior descending [LAD], 5.0 +/- 0.05% vs. 18.0 +/- 4.5%, p = 0.0009; right coronary artery [RCA], 4.0 +/- 0.07% vs. 32.7 +/- 12.7%, p = 0.006). Moreover, the coronary blood flow volume reserve was reduced in ASO patients compared with control patients after intracoronary infusion of acetylcholine (2.3 +/- 0.9 vs. 4.9 +/- 1.7, p = 0.0003) or adenosine (2.7 +/- 1.5 vs. 5 +/- 0.5, p = 0.002). CONCLUSIONS: Epicardial coronary arteries fail to dilate normally in children after ASO, and the calculated coronary flow volume reserve is consequently reduced.

Child↗

[The anatomy of coronary arteries in the main vascular transposition].

The analysis of the coronary arteries (CA) morphology in the main vessels transposition (MVT) cases was presented, basing on the clinical and cadaveric investigations data. During performance of 88 operations there were revealed 8 different morphological variants of the CA branching. There were studied 8 heart macropreparations with MVT and there were disclosed 4 different types of the CA morphology.

Coronary Vessels↗