SEARCH · PubMed Health

Results for “Drinking Behavior”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,153 records · Page 64Linked to original sources

PubMed2006

Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats.

We have recently observed increased stress responsiveness with regard to alcohol consumption in male rats that consumed alcohol since their adolescent period. Thus, early age at drinking onset can induce enhanced stress-induced alcohol drinking in male rats. However, it is not known whether female rats respond in a similar way. Therefore, we compared the drinking behavior of two female Wistar rat groups--one that acquired alcohol consumption during adolescence (adolescent group) and the other that acquired their drinking during adulthood (adult group) in a model of long-term voluntary alcohol drinking with repeated deprivation and stress phases. Furthermore, we studied the influence of age at drinking onset on the efficacy of acamprosate treatment. Thirty-nine female Wistar rats aged 31 days (adolescents) and 71 days (adults) were given ad libitum access to water, as well as to 5% and 20% ethanol solutions during an observation period of 29 weeks. A deprivation phase of 14 days was introduced following 8 weeks of access to alcohol in order to measure the alcohol deprivation effect (ADE). After 15 and 25 weeks of alcohol access, all animals were subjected for 3 consecutive days of forced swim and electric foot-shock stress, respectively. After 29 weeks of access to alcohol all animals underwent a second deprivation phase and the subsequent ADE was measured either under acamprosate (200 mg/kg) or vehicle treatment. Drinking before the first deprivation phase was not different between animal groups. However, the expression of the first ADE was more pronounced in adult female rats and alcohol intake stayed increased for the remainder of the experiment in the adult group. Both repeated swim stress and foot-shock stress produced a more pronounced increase in ethanol consumption in the adolescent group compared to the adult group. Acamprosate reduced relapse-like drinking in the adult female rat group. However, it had no effect on the ADE in the adolescent group. In conclusion, female rats that initiate alcohol consumption during adolescence might be more susceptible to stress-induced alcohol consumption. Adolescent alcohol drinking might also result in a reduced response to acamprosate.

Acamprosate↗

PubMed2000

Peer networks among heavy, regular and infrequent drinkers prior to marriage.

OBJECTIVE: Research has consistently demonstrated that, among adolescents, the characteristics of one's peers are important predictors of substance abuse. The impact of the peer network on adult drinking, however, has received considerably less attention. The purpose of the present study was to examine social network characteristics that are associated with heavy drinking in adulthood prior to marriage. METHOD: Couples were recruited at the time of their first marriage. Husbands and wives were each given identical questionnaire packets to complete at home, independently, as well as a postage-paid envelope for packet return. A broad range of constructs was assessed; included were personality characteristics, relationship functioning, drinking behavior and social network characteristics. Complete data were obtained from 471 husbands and 471 wives. RESULTS: The social networks of heavy-drinking men, compared to men drinking regularly or infrequently, were younger, more likely to be male and unmarried and consisted of friends rather than family or others. For both men and women, "drinking buddies" accounted for nearly 75% of the heavy drinkers' peer networks. The overall ratings of support and conflict created by peers did not differ according to drinking group, for either men or women. CONCLUSIONS: Prior to marriage, the social networks of heavy drinkers differ considerably from the networks of regular or infrequent drinkers with regard to the drinking patterns of their peers. An important finding was that heavy drinkers appear to experience a similar level of emotional, financial and practical support from their peer network compared to regular or infrequent drinkers.

Adult↗

PubMed2003

Heavy drinking and alcohol policy enforcement in a statewide public college system.

OBJECTIVE: To assess the association between heavy drinking and alcohol policy enforcement following the institution of a new system-wide alcohol policy at Massachusetts public colleges and universities. METHOD: Students (N = 1,252: 59% women) at 11 study schools completed a questionnaire that assessed drinking behaviors and alcohol-associated problems. College deans and campus security officers completed questionnaires assessing policy implementation and enforcement. We compared heavy drinking rates among the 11 schools and measured the association between schools' heavy episodic drinking rates and enforcement index scores based on deans' and security officers' reports of policy enforcement. RESULTS: Rates of heavy episodic drinking varied widely among the 11 schools (range: 36%-71%). The percentage of students reporting strict/very strict policy enforcement also varied widely (35%-90%). In this small sample of colleges, heavy drinking rates among students living on campus tended to be negatively associated with stricter alcohol policy enforcement reports by security officers (Pearson's r = -0.64. p < .05) and the association appeared to be linear. Heavy drinking was not associated with enforcement reports by deans (Pearson's r = 0.17, p = NS). CONCLUSIONS: Within this single state system, stricter enforcement by campus security officers of policies that limit underage drinking tends to be associated with lower rates of heavy drinking by students.

Adolescent↗

PubMed1979

Patterns of drinking among the deaf.

Thirty-nine White deaf persons functioning normally within the general hearing community were surveyed on a variety of factors concerning their use of alcohol, and compared to the data from two comparable hearing samples reported previously in the literature. No significant differences were found between the deaf and hearing samples on patterns of drinking or other parameters of alcohol use. Heavier alcohol use among the deaf correlated significantly with reported frequency of driving after having drunk too much, age of having had the first drink, ever having been drunk, feeling guilt over drinking too much, and others criticizing the respondent for drinking behavior. Heavier use also tended to be correlated with attendance at an all-deaf school. Implications of the findings of similar drinking patterns for the deaf and the hearing are discussed in terms of the lack of specific rehabilitation facilities for the deaf, along with possible reasons for the lack of use by deaf clients of alcohol rehabilitation agencies in the community.

Adolescent↗

PubMed1997

Validation of a measure of excessive drinking: frequency per year that BAL exceeds 0.08%.

Although self-report data are generally evaluated as reliable, validity estimates for self-reported drinking behavior are not as favorable. A new method of measurement addressing problems currently associated with the questionable validity of self-report drinking information is introduced. Study 1 tests the correspondence between the new measure (occasions per year blood alcohol level exceeded 0.08%), traditional self-report measures, and laboratory alcohol consumption. The novel measure correlated most strongly with volume of alcohol consumed in the laboratory compared to the traditional measures. In Study 2 the novel measure was favored over a traditional measure when discriminating between the presence and absence of problem-drinking symptoms.

Adolescent↗

PubMed1992

[Nicotine-induced ambulatory stimulant effect and its reverse tolerance].

Nicotine-induced ambulatory stimulant effect and its reverse tolerance produced by daily administration of nicotine in rats were investigated. Nicotine (0.5 and 1.0 mg/kg, sc) increased the ambulatory activity, which was enhanced by the daily administration of nicotine. Although total ambulatory activity and drinking behavior during 20 h (from 13:00 to 9:00) following daily administration of nicotine (1.0 mg/kg, sc) for 7 successive days decreased, these behaviors returned to the control levels after the nicotine-treatment period. Moreover the periods (tau s) of the ambulatory activity and drinking were not changed by daily injections of nicotine (1.0 mg/kg, sc) for 6 successive days. The enhancement of the ambulatory stimulant effect produced by daily injections of nicotine (0.5 mg/kg) was antagonized by mecamylamine (0.2 mg/kg) and haloperidol (0.05, 0.1 and 0.2 mg/kg), which were subcutaneously administered at 20 min before injections of nicotine. These results suggest that the enhancement of nicotine-induced ambulatory stimulant effect by the daily administration of nicotine is concerned with central dopaminergic stimulation through the nicotinic acetylcholine receptor in the rat brain.

Animals↗

PubMed1987

Heavy and problem drinking in an American blue-collar population: implications for prevention.

This paper presents the findings of a prevention-oriented research project designed to identify the familial and socio-environmental precursors of heavy drinking in a blue-collar population. Using an ethnographic and primarily qualitative approach to data collection, this study examines alcohol use and drinking behavior in relation to both the family as a unit, as well as the sociocultural context in which it is embedded. It reports primarily on features of cultural, workplace, and community environments that are related to heavy or moderate drinking in the subject population. The sample consists of 30 families, 15 where the father is a heavy drinker and 15 where he is a moderate drinker. The sample was drawn from the workforce of a large manufacturing plant that closed in 1982. The social organization of the workplace, including the important factors of job alienation, job stress, inconsistent social controls, and the evolution of a 'drinking culture,' is implicated by this research to be the primary vehicle for promoting high levels of alcohol use. Although the role of the workplace in encouraging certain alcohol behaviors was predominant, the data suggest that it alone may not be sufficient for causing alcohol problems. In particular, the central importance of drinking in work-related social contexts and the relative permissiveness of the work environment was found to promote heavy drinking among individuals who were of sociocultural backgrounds where heavy drinking was permitted or even encouraged; reported a lack of effective male role models when growing up; and restricted leisure activities to male-oriented peer groups most often met through work-related contexts. Conversely factors that appeared protective of developing high-risk drinking patterns were family religious involvement, and participation of fathers in non-work related social groups that usually involved their wives and children. We conclude the paper by offering suggestions as to how these findings might lead to constructive strategies for the primary prevention of alcohol problems in the context of the workplace and community.

Adult↗

PubMed1989

Psychosocial correlates of alcohol intake among women aged 45 to 64 years: the Framingham Study.

This study of 749 women, aged 45 to 64 years, investigates the psychological, behavioral, and social correlates of alcohol intake. These data from the Framingham Study are uniquely based on a community sample of women, which results in a normative study of drinking behavior in women. Two measures of alcohol intake were utilized in these analyses: (1) the frequency of alcohol intake over 1 week and (2) drinking vs abstaining from alcohol. Among this sample of women, increased socioeconomic status, worrying about aging, and being easily upset were positively associated with frequency of alcohol intake. The rigid attitude scale was the strongest discriminating variable for drinkers vs nondrinkers. Older women were more likely to be nondrinkers compared to younger women, however, among older women, being a homemaker was significantly associated with increased alcohol intake. Contrarily, younger women who were homemakers were more likely to be abstainers than women employed outside the home. As would be expected, cigarette smoking was associated with drinking alcohol.

Adaptation, Psychological↗

PubMed2001

Activation of alcohol expectancies in memory in relation to limb of the blood alcohol curve.

Attempts to understand the mechanism by which alcohol expectancies might influence drinking have related activation of expectancies in memory to alcohol use. Limb of the blood alcohol curve, however, has not been considered. In the present study, 527 undergraduates completed the Anticipated Biphasic Alcohol Effects Scale and a drinking measure. Multidimensional scaling was used to map expectancies into memory network format, and likely activation of expectancies was empirically modeled. Heavier drinkers were most likely to activate positive and arousing expectancies associated with the ascending limb, whereas lighter drinkers were most likely to activate negative and sedating expectancies associated with the descending limb. These findings add to the literature suggesting that activation of expectancies in memory may be an important determinant of drinking behavior and a promising target for intervention strategies.

Adult↗

PubMed1980

A sweat-patch test for alcohol consumption: evaluation in continuous and episodic drinkers.

We evaluated the sweat-patch test for its ability to detect alcohol consumption. During an 8-day study, volunteers drank whisky while wearing sweat-patches that collected sweat continuously at a steady rate. We offered 1.0, 2.0, or 5.0 g ethanol/kg/day to 6 continuous drinkers, and 5.0 g ethanol/kg/day for 2 days to 8 episodic drinkers, and removed sweat patches after 2, 4, 6, and 8 days. The concentration of ethanol in the collected sweat (Cs) rose: (1) progressively with the amount of alcohol consumed: and (2) linearly with the mean concentration of ethanol in the blood (Cb) during the sweat collection period (In Cs = 0.80 In Cb - 1.40; r = 0.93, p < 0.001). The test clearly distinguished drinkers from nondrinkers (Cs < 0.0022 G/L when no ethanol consumed; Cs > 0.0067 G/L when 0.5 G ethanol/kg/day consumed and when Cb > 0.013 G/L). The sweat patch test provides an objective index of drinking behavior with potential applications in clinical practice and research.

Alcohol Drinking↗

PubMed2001

Quantitative autoradiography of mu-opioid receptors in the CNS of high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats.

BACKGROUND: The binding of [3H]DAMGO to mu-opioid sites was measured in the CNS of selectively bred high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats to test the hypothesis that high alcohol preference is associated with higher densities of mu-opioid receptors. METHODS: Adult, alcohol-naïve male HAD and LAD rats from replicate line 1 were decapitated and their brains frozen in isopentane. Brain sections were incubated with 5 nM [3H]DAMGO, and nonspecific binding was determined in the presence of unlabeled DAMGO. Films were exposed for 60 days, then analyzed using quantitative autoradiography. RESULTS: The densities of [3H]DAMGO binding sites were measured within subregions of neocortex, limbic system, basal ganglia, diencephalon, and brainstem. LAD rats had significantly higher [3H]DAMGO binding (10-30%) than HAD rats within the anterior dorsal hippocampus (CA2), posterior hippocampus (dorsal CA1, and ventral CA1, CA3, and dentate gyrus), thalamus (medial dorsal, lateral, medial dorsal, central, ventral lateral, ventral medial, and ventral medial geniculate nuclei), habenula, and amygdala. No significant interline differences were found in the prefrontal, cingulate, frontal, parietal, temporal, occipital or entorhinal cortices, olfactory tubercle, nucleus accumbens, lateral septum, ventral tegmental area, hypothalamus, caudate-putamen, substantia nigra, claustrum, central gray, or superior colliculus. CONCLUSIONS: The present findings with the HAD and LAD lines do not support the hypothesis that high alcohol preference is associated with higher densities of CNS mu-opioid receptors. Instead, the present results, in combination with previously published findings, suggest that the mu-opioid system may play a complex role in regulating high-alcohol-drinking behavior.

Alcohol Drinking↗

PubMed1994

[A study on alcohol drinking pattern in freshmen and sophomores].

Alcohol drinking pattern in 871 freshmen and sophomores of Han nationality was studied. Results showed 92.7% of the male and 72.9% of the female students were alcohol drinkers. There were highly significant differences in alcohol drinking pattern and types of alcoholic beverage they drank between males and females (P < 0.0001), and between students specializing in different subjects (P < 0.01). Alcohol drinking pattern of male students was influenced by their academic concerns and the drinking behavior of their fathers and friends.

Adult↗

PubMed2003

Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice.

Heterozygous brain-derived neurotrophic factor (BDNF) (+/-) mice display abnormalities in central serotonergic neurotransmission, develop decrements in serotonergic innervation of the forebrain, and exhibit enhanced intermale aggressiveness. As disturbances of serotonin neurotransmission are implicated in alcohol abuse and aggression, we have examined in BDNF (+/-) mice alcohol drinking behavior, as well as central 5-hydroxytryptamine (5-HT)1A receptor function at the level of 5-HT1A receptor-G protein interaction. BDNF (+/-) mice displayed increased ethanol intake in a two-bottle choice procedure. There was no difference in the preference ratio for non-alcoholic tastants (i.e. quinine or saccharin) between genotypes. In the brains of alcohol-naive mice, we measured [35S]GTP gamma S binding stimulated by the 5-HT1A receptor agonist (+/-)-8-hydroxy-2-dipropyl-aminotetralin hydrobromide (8-OH-DPAT; 1 microM). In BDNF (+/-) versus wild-type (WT) mice, 5-HT1A receptor-stimulated [35S]GTP gamma S binding was significantly attenuated in the median raphe nucleus. There was a decrease in (+/-)8-OH-DPAT-stimulated [35S]GTP gamma S binding in the dorsal raphe, which did not reach statistical significance. In the hippocampus, 5-HT1A receptor-stimulated [35S]GTP gamma S binding was significantly attenuated in BDNF (+/-) mice. 5-HT1A receptor-stimulated [35S]GTP gamma S binding was attenuated in the anterior cingulate cortex and lateral septum, although these reductions did not reach statistical significance. 5-HT1A receptor number was not different between genotypes in any area of brain examined, suggesting that 5-HT1A receptor function, specifically the capacity of the 5-HT1A receptor to activate G proteins, is attenuated in BDNF (+/-) mice.

8-Hydroxy-2-(di-n-propylamino)tetralin↗

PubMed2002

The relationship between abstinence for one year following pretreatment assessment and alcohol use and other functioning at two years in individuals presenting for alcohol treatment.

OBJECTIVE: The purpose of this study was to replicate and extend research that shows abstinence from alcohol during the first year following treatment predicts better longer term functioning in alcohol use and other areas. METHOD: The subjects were 187 men and women who had participated in a clinical trial of the differential effectiveness of two behavioral treatments for alcohol problems as a function of subject characteristics. All subjects who participated in this phase of the study were classified as either abstinent from alcohol or not based on their drinking behavior during the first 12 months following treatment initiation. Subjects' alcohol use and other behaviors were evaluated for Months 13-24. The primary dependent variables of interest were alcohol use, self-efficacy, and psychological functioning. RESULTS: A comparison of the two abstinence groups showed that abstainers, compared to drinkers, had less alcohol use, higher self-efficacy, and better psychological functioning. CONCLUSIONS The results suggest the association is robust between abstinence during the first year following treatment initiation or cessation and later functioning, and extend this finding to include psychological functioning. Future research should focus on possible mediators of the abstinence correlations with later behavior that are of theoretical and practical importance, and on specifying gradients of duration of abstinence or other drinking patterns reflecting improvement and their relationship to longer term functioning.

Adult↗

PubMed1989

Family history of alcoholism, youthful antisocial behavior and problem drinking among DWI offenders.

This study assessed the impact of family history of alcoholism and antisocial behavior on problem drinking among male first-time DWI offenders. A sample of 123 men in DWI classes were assessed on demographic factors, antisocial behavior and family history of alcoholism. Also, measures of current and past drinking problems were assessed, including scales of perceived ability to control consumption, degree of physical dependence, occurrence of alcohol-related problems and preoccupation with alcohol. The results indicated that while family history of alcohol and antisocial behavior were not significantly related to quantity/frequency of alcohol consumption or alcohol-related problems, family history was related to drink duration. Main effects of family history and antisocial behavior were found for preoccupation with alcohol and physical dependence. There was a significant interaction with respect to perceived ability to control drinking. Results are discussed with regard to the implication that family history of alcoholism and antisocial behavior may influence the development of important precursors to alcoholism.

Adult↗

PubMed2000

Applications of video mixing and digital overlay to neuroethology.

Neuroethological experiments often require video images of animal behavior and recordings of physiological data to be acquired simultaneously, synchronized with each other, stored, and analyzed together. The use of inexpensive multimedia computers offers new possibilities for mixing video images, analog voltages, and computer data, storing these combined signals to videotape, and extracting quantitative data for analysis. In this paper, we summarize methods for mixing images from multiple video cameras and a Macintosh computer display to facilitate manipulation of data generated during our neurophysiological and behavioral research. These technologies enhance accuracy, speed, and flexibility during experiments, and facilitate selecting and extracting quantitative data from the videotape for further analysis. Three applications are presented: (A) we used an analog video mixer to synchronize neurophysiological recordings with ongoing behaviors of freely moving rats; (B) we used a chroma keyed digital overlay to generate positional data for the rat's face during drinking behavior; and (C) we combined a computer model of a rat's head and whiskers with videos of exploratory behaviors to better track and quantify movements in three dimensions. Although the applications described here are specific to our neuroethological work, these methods will be useful to anyone wishing to combine the signals from multiple video sources into a single image or to extract series of positional or movement data from video frames without frame grabbing.

Animals↗

PubMed1995

Ventral tegmental area opioid mechanisms and modulation of ingestive behavior.

In this paper we report on the effects of intra-VTA infusion of opioid agonists on rat ingestive behavior in a variety of experimental contexts. When the animals were tested outside of their home cages surrounded only by food-pellets (Experiment 1), the injection of the mu-opioid agonist DAMGO, but not the kappa-opioid agonist U-50,488H, into the ventral tegmental area facilitated food-related behaviors, decreasing the latency to feed and increasing the number of interactions with food. When, as in Experiment 2, gnawable objects and a drinking tube were also available, intra-VTA DAMGO gnawing and drinking behaviors, whereas the effects on feeding were negligible. These effects intra-VTA DAMGO increased were greatly enhanced in rats that underwent repeated treatments with amphetamine. On the other hand, when food-related behaviors were studied in a home-cage, where access to the food supply was achieved by entry into a tunnel, latency to feed and total food-intake were not enhanced in tests made during either the dark or the light phase (Experiment 3 and 4). This was true whether powdered standard lab chow or a highly palatable food was available. It appears that when a number of alternative incentive stimuli are available, increases in dopamine transmission such as that induced by intra-VTA DAMGO may ultimately have the effect of interfering with behavior normally directed primarily to one of these stimuli, by enhancing the salience of others. These effects bears some resemblance to the effects of tail-pinch and electrical brain stimulation of the medial forebrain bundle-lateral hypothalamic area on the responses to natural incentive stimuli.

3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cycloh↗

PubMed2006

Reducing alcohol-impaired driving crashes through the use of social marketing.

Over the past decade there has been little decrease in the number of alcohol-related driving fatalities. During this time most interventions have been educational or legal. This paper presents the results of a field experiment that used social marketing to introduce a new ride program into three rural communities. Almost all people in the 21-34-year-old target know that they should not drive while impaired, and most agree it is not a good thing to do, but for many the opportunity to behave properly does not exist. The Road Crew program was developed using new product development techniques and implemented by developing broad coalitions within the communities. A key feature of the program included rides to, between, and home from bars in older luxury vehicles. Results showed a significant shift in riding/driving behavior, especially among 21-34-year olds, a projected 17% decline in alcohol-related crashes in the first year, no increase in drinking behavior, and large savings between the reactive cost of cleaning up after a crash and the proactive cost of avoiding a crash. Programs have become self-sustaining based on fares and tavern contributions, and have become part of the life style in the treatment communities.

Accidents, Traffic↗