Reduction of dentin hypersensitivity using fluoride iontophoresis.
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It has been analyzed the possibility to modify the cutaneous ionthophoresis of drugs by means of an original apparatus through which experiments are performed on isolated rat skin. The test drug employed as the salicylic acid (SA). The presence of parasite ions decreases the passage of SA through the skin with an effect which is proportional to the salt concentration. The sodium salicylate is transferred less than SA. It has been analyzed the effect of drugs increasing the skin permeability like dimethylsulfoxide (DMSO) and dimethylformamide (DMF). DMSO in combination with SA facilitates the SA cutaneous ionthophoresis, while DMF does not.
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The work presents the data of clinical and laboratory observations of 68 patients treated by electrophoresis of antibiotics in exacerbation of the suppurative process in burn wounds after autodermoplasty. It has been found that the antibiotic electrophoresis inhibits the microflora in the burn wound, results in the repair of the epithelial cover and makes the period of the hospital treatment 10-14 days shorter.
All participants with a baseline print score of greater than 1 demonstrated reduced sweating for up to six weeks following treatment with the Drionic device. Because of experimental design flaw, similar results were not obtained from those participants producing a baseline sweat print of 1. Therefore, the impression from these results is that, while not completely supported by objective data, it is possible to substantiate the subjective information related by patients in the control of hyperhidrosis.