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At least 1,171 records · Page 65Linked to original sources

Perforating (through-and-through) injuries of the globe. Surgical results with vitrectomy.

Fifty-one eyes of 48 patients with perforating (through-and-through) injuries of the globe were treated with vitrectomy during a 12-year period. Functional success was obtained in 32 eyes (63%), anatomic success was obtained in nine eyes (17%), and treatment failed in 10 eyes (20%). In 16 eyes (32%), 20/20 to 20/100 visual acuity was obtained; in 17 eyes (33%), 20/200 to 5/200 visual acuity was obtained; and in 18 eyes (35%), less than 5/200 visual acuity was obtained. The mechanism of injury was an important prognostic indicator of final visual outcome. Eight (62%) of 13 eyes that sustained knife or nail injuries achieved a final visual acuity of 20/50 or better, while only six (16%) of 38 eyes [corrected] with missile injuries achieved a similar level of acuity. Final visual outcome correlated well with the state of the macula and was not predicted by preoperative visual acuity. Despite improvement in surgical techniques and instrumentation, no trend toward improved visual outcomes was identified during the 12-year period.

Adolescent↗

Posterior chamber intraocular lens implantation combined with lensectomy-vitrectomy and intraretinal foreign-body removal.

Two patients with intraretinal foreign bodies and traumatic cataracts were treated with pars plana lensectomy, vitrectomy, and removal of the foreign body. In each case, it was technically possible to preserve the anterior capsule despite small but obvious rents caused by the foreign body. This allowed support for the placement of a posterior chamber intraocular lens at the time of the initial repair. Posterior chamber intraocular lens implantation may be a useful adjunctive step in the treatment of selected patients with intraocular foreign bodies.

Adult↗

A new device for noncontact wide-angle viewing of the fundus during vitrectomy.

Noncontact wide-angle viewing of the fundus during vitrectomy has heretofore relied on an image inverter and a 90-diopter lens fixed with a tube under the microscope. A new device in which the 90-diopter lens is not connected to the microscope but, rather, is connected to an independent support system is described. This device offers many advantages: (1) focusing on the various parts of the eye during vitreous surgery need not be done manually but is achieved by the up or down movement of the microscope, (2) translation of the microscope is easier during tilting of the eye, (3) a lateral slit-lamp can be easily added for illumination of the fundus, and (4) there is no risk that the 90-diopter lens will touch the cornea.

Equipment Design↗

The source of coagulase-negative staphylococci in the Endophthalmitis Vitrectomy Study. A comparison of eyelid and intraocular isolates using pulsed-field gel electrophoresis.

OBJECTIVE: To determine the species distribution of coagulase-negative staphylococci (CoNS) in patients with endophthalmitis and to ascertain whether the patient's own flora was a major source of postoperative endophthalmitis following cataract extraction. METHODS: In a 4-year multicenter prospective study, 524 bacterial isolates were submitted from 225 Endophthalmitis Vitrectomy Study patients. From the 524 isolates, 250 represented CoNS cultured from the anterior chamber, the vitreous, or both of the 225 patients. Where possible, paired isolates from an individual patient's eyelid and intraocular compartment(s) were studied by pulsed-field gel electrophoresis, an established molecular strain-typing technique. RESULTS: From all sites the most frequently isolated CoNS were Staphylococcus epidermidis (81.9%) and Staphylococcus lugdunensis (5.9%). Where analysis was possible, eyelid isolates were indistinguishable from intraocular isolates in 71 (67.7%) of 105 comparisons. Non-S epidermidis CoNS caused postoperative endophthalmitis in 5 patients. Four of the 5 had postoperative endophthalmitis caused by S lugdunensis and 1 by Staphylococcus haemolyticus. CONCLUSIONS: Coagulase-negative staphylococci from the patient's periocular skin flora play a significant role in causing intraocular infections, and non-S epidermidis CoNS play a small but significant role. These results reinforce the necessity to follow stringent surgical site preparation prior to eye surgery.

Anterior Chamber↗

Pars plana vitrectomy in aphakic retinal detachments.

Thirty-three cases of aphakic retinal detachment have been treated by pars plana vitrectomy and retinopexy. This procedure allowed us to lower the incidence of postoperative massive periretinal proliferation from 15,4%, in a series that was performed by a classical method, to 6% in the pars plana treated group.

Aphakia↗

Lensectomy and vitrectomy in the presence of filtering blebs.

We describe a technique for preserving a filtering bleb in glaucoma patients undergoing pars plana lensectomy and vitrectomy. It involves making a conjunctival incision away from the filtering site and injecting the anterior chamber and bleb with (hyaluronic acid) Healon before vitreous surgery is begun.

Adult↗

Pars plana vitrectomy in a case of amyloidosis of the vitreous.

A pars plana vitrectomy was performed in a case of vitreous opacities caused by generalized amyloidosis. Vision improved from 2/300 to 5/5 after surgery. The vitreous specimen stained orange-red with congo-red staining and showed the typical yellow-green birefringence with polarized light. The literature on the surgical treatment of amyloidosis of the vitreous is reviewed.

Aged↗

Radical vitrectomy and silicone-oil injection in the treatment of proliferative vitreoretinopathy following retinal detachment.

Eighteen consecutive patients with proliferative vitreoretinopathy following retinal detachment were treated with radical pars-plana vitrectomy and silicone oil injection. At least 6 months follow-up demonstrated fully attached retinas in 12 patients, partly attached retinas in 3 patients and primary failure in 3 patients. The visual fields revealed serious defects in 50% of those patients with attached retinas. The expected complications such as cataract (100%), glaucoma, corneal decompensation and subretinal oil were seen as well, but the complication rate is expected to diminish with newer surgical techniques.

Aged↗

Evaluation of a single intravitreal injection of dexamethasone phosphate in vitrectomy surgery for diabetic retinopathy complications.

For evaluation of the efficacy and toxicity of dexamethasone phosphate after pars plana vitrectomy, 27 randomly selected eyes received 0.8 mg intravitreal dexamethasone phosphate and 30 control eyes did not receive this injection. No signs of dexamethasone phosphate toxicity were observed during 6 months of follow-up evaluations. Visual acuities of 20/40 or better were obtained in 26% of the dexamethasone-treated group and 33% of the control group, and those of 20/200 or better were obtained in 74% of the dexamethasone-treated eyes and 73% of the control eyes. Moderate anterior chamber flare or fibrin formation occurred in only 15% of the dexamethasone-treated eyes but in 27% of the control eyes one day after surgery. Lens changes occurred equally in both groups. None of the eyes in either group developed substantial intraocular proliferation or membranes following surgery.

Adult↗

Collagen shields and intraocular drug delivery: concentration of gentamicin in the aqueous and vitreous of a rabbit eye after lensectomy and vitrectomy.

Five albino New Zealand rabbits underwent bilateral lensectomy and vitrectomy. All left eyes were fitted with a collagen shield that had been soaked for 5 min in 2.0 mL of gentamicin solution (40 mg/mL for IV use). Right eyes were treated with fortified gentamicin drops (13.6 mg/mL) every 30 min for 12 hrs. Aqueous and vitreous specimens were obtained at the following time intervals: 1, 2, 4, 8, 12 and 24 hrs. We found the gentamicin concentrations to be higher in the aqueous of all eyes treated with fortified gentamicin drops. Only those eyes treated with fortified gentamicin drops attained a therapeutic drug level (4 micrograms-9 micrograms/mL) in the aqueous. Therapeutic drug levels were not attained in the vitreous of either treatment group.

Administration, Topical↗

Pars plana vitrectomy for retinal detachment due to internal posterior ophthalmomyiasis after cataract extraction.

BACKGROUND: The authors report a case of posterior internal ophthalmomyiasis causing vitreous haemorrhage and retinal detachment after uncomplicated cataract extraction. CASE REPORT: The patient suffered an abrupt vitreous haemorrhage 9 days after ECCE and posterior chamber IOL implantation. After 2 months the haemorrhage did not clear up and a retinal detachment arose. The patient underwent encircling scleral buckle, pars plana vitrectomy and fluid-gas exchange. In course of intervention the surgeon removed from the vitreous chamber a 14-mm-long round worm subsequently identified as a dipterous larva of the Sarcophagidae family. DISCUSSION: The patient showed no sign of subretinal tracking or retinal breaks or holes. The sclerocorneal surgical wound seems the most likely site of entrance of the parasite, and this would then be the first reported case of myiasis with no RPE tracking.

Aged↗

Use of vancomycin in vitrectomy infusion solution and evaluation of retinal toxicity.

The retinal toxicity of vancomycin in infusion solution used in vitrectomy and lensectomy was investigated in rabbit eyes by means of electroretinography and histologic study (light microscopy). Concentrations of 8 micrograms/ml, 16 micrograms/ml, and 32 micrograms/ml of vancomycin in balanced salt solution caused no abnormal ERG or histologic changes. However, ERG amplitude depression and abnormal histologic changes occurred when the concentration of 100 micrograms/ml of vancomycin was used.

Animals↗

Vitrectomy techniques in late-stage Coats'-like exudative retinal detachment.

Retinal telangiectasia is the hallmark of Coats' disease. In the late stages, leakage from these abnormal vessels can result in a total, bullous exudative retinal detachment with cholesterol-laden subretinal fluid. Secondary angle-closure glaucoma may result in a blind and painful eye which may require enucleation or evisceration. Surgical reattachment of the retina and destruction of the retinal telangiectasia may preserve these eyes. We have found that vitrectomy, internal drainage of subretinal fluid and cholesterol, direct treatment of the retinal telangiectasia with intraocular diathermy and intravitreal gas or silicone oil injection are effective surgical techniques for salvaging these severely damaged eyes.

Adult↗

Gas-mediated vitreous compression: an experimental alternative to mechanized vitrectomy.

We have developed a simple technique in rabbit and baboon eyes that utilizes intravitreally injected perfluoropropane gas, which expands slowly to efficiently compress and displace nearly completely the vitreous body. There is cataract formation after extended contact of the gas bubble with the lens. However, it is rapidly reversible by reducing the duration of lens contact (gas-fluid exchange) and by using young animals. No long-term alterations in intraocular pressure or retinal function were observed, as determined by electroretinography, during the 4-month test period. Gross examination and scanning electron microscopy revealed that the vitreous cavity, shortly after full expansion of the gas bubble, was practically free of collagen. The vitreous body had been detached from most of the retina and compressed into a collagenous strand between the optic nerve head and lens in the rabbit eyes, and there was also a dense collagen accumulation on the inferior retinal surface and anterior vitreous base in the rabbits and the baboon. Large areas of the retina and medullary wings were stripped of overlying collagen. By the end of 4 months, the compressed vitreous body had expanded to become an irregular structure that remained separated from the retina in areas of previous detachment. Mechanized vitrectomy is a difficult procedure often needed in experimental work. We believe that the vitreous compression and gas-fluid exchange technique is a valid alterative to a mechanical approach. We also believe that we have a model that simulates the human situation of posterior vitreous detachment and vitreous syneresis.

Animals↗

Pars plana vitrectomy in aphakic and pseudophakic retinal detachment.

Eighty-two consecutive aphakic or pseudophakic retinal detachments were treated by buckling and vitrectomy procedures. Functional results (86.6%) and the incidence of proliferative vitreoretinopathy (11%) were comparable with reports of cases treated by the classic method.

Aphakia↗

Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: results at 18 months.

Sixty-five eyes with giant retinal tears previously reviewed at 6 months after vitrectomy and fluid/silicone-oil exchange were again reviewed 18 months after surgery. The retina remained attached in 54 eyes (83%), and of these 32 (57%) had visual acuities of 6/60 or better. Poor acuities were attributed in most cases to cataract associated with silicone-oil contact or macular damage from preoperative macular detachment. Glaucoma occurred chiefly in those eyes which were aphakic prior to surgery, or were rendered aphakic at surgery, but did not influence the visual outcome at this stage. Encouraging results of surgery after 6 months were confirmed after 18 months, although the level of vision had fallen in some cases due to the development of lens opacities.

Adolescent↗

The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy.

We have used silicone-oil injection in a consecutive series of 44 patients with retinal detachment and advanced proliferative vitreoretinopathy, all of whom had previously failed to reattach with vitrectomy, membrane peeling, and scleral buckling. After a minimal follow-up period of 6 months, complete anatomic retinal reattachment posterior to the encircling scleral buckle was obtained in 64% of these eyes. Ambulatory visual acuity (5/200 or better) was achieved in 57% of the anatomically successful cases. Silicone-oil removal was performed in 69% of the anatomically and visually successful eyes without recurrent retinal detachment. Because of the frequent and severe complications associated with the use of silicone oil, we recommend that silicone-oil injection be considered only when conventional vitreoretinal techniques have failed to achieve retinal reattachment.

Eye Diseases↗

Combined vitrectomy and scleral resection in the therapy of massive epiretinal fibrous membranes due to diabetic retinopathy.

Between December 1981 and June 1984 scleral resection was performed in 35 patients suffering from end-stage proliferative diabetic retinopathy with traction retinal detachment involving the macula. In all cases, vitrectomy, membranectomy, segmentation, and delamination proved to be insufficient to mobilize the "shrunken" retina. In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye. Visual acuity thus achieved ranged between 6/24 and 1/60, corresponding to an improvement of visual acuity compared with the preoperative situation in about one-third of the cases successfully treated (8 eyes).

Diabetic Retinopathy↗