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Prolonged coronary splinting in the management of acute coronary closure.

Acute closure is an infrequent but serious complication of PTCA that is often unsuccessfully treated by repeat dilatation. Two patients with acute closure refractory to repeat conventional PTCA were treated with prolonged coronary "splinting" using low-pressure reperfusion catheter balloon inflations of 11 and 15 h duration. The patients developed no chest pain or ST-segment changes during this period. The serum creatine kinase rose to 738 and 372 U/L, respectively. Neither patient evolved a Q-wave myocardial infarction. Both patients remain asymptomatic after 6 months of follow-up.

Aged↗

Deletion mutagenesis using an 'M13 splint': the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate.

The X-ray crystallographic structure of tyrosyl-tRNA synthetase (TyrTS) comprises only the N-terminal 320 amino acids of the molecule as the C-terminal 99 amino acids are poorly ordered in the crystal. A new technique, employing a single-stranded M13 splint, has been used to direct a deletion in the cloned gene of TyrTS so as to remove the disordered C-terminal region. We find that the truncated enzyme catalyses the formation of tyrosyl adenylate with unchanged Kcat and Km values and the crystallographic model must therefore include all the binding and catalytic residues involved in tyrosine activation. However, the truncated enzyme no longer binds tRNATyr or transfers tyrosine to tRNATyr. This indicates that the structural division of TyrTS is equally a functional one: the N-terminal structural domain catalyses tyrosine activation while the disordered C-terminal domain carries major determinants in tRNA binding.

Adenosine Monophosphate↗

Orthotopic kidney transplantation in the rat with non-splinted end-to-end ureteric anastomosis: details of a technique.

A detailed description is presented of an improved technique of orthotopic rat kidney transplantation with end-to-end anastomoses of the renal vessels, non-splinted end-to-end ureteric anastomosis and simultaneous bilateral nephrectomy. Forty-four consecutive transplantations are analysed. No failure due to complications of the vascular anastomoses occurred. The ureteric anastomoses were followed by stenosis in only two cases (5%), one of which was reconstructed. The operation times for the vascular anastomoses were 16-24 min, with an average of 20 min, and for complete transplantation 50 min. Therefore, our method seems to be less time consuming than other common techniques of renal transplantation. The technique described has produced a success rate of 95% and guarantees a standardised and reproducible organ quality.

Animals↗

Compound osteosynthesis of pathological fractures of the proximal femoral shaft. Experimental studies on the biomechanical effects of additional intramedullary splinting.

The biomechanical stability of two compound osteosynthesis techniques with and without intramedullary splinting were compared in 20 paired cadaver femora. Group A was stabilised using a contoured 12-hole DC plate and polymethylmethacrylate cement. In group B an additional intramedullary semi-diameter osteosynthesis plate was inserted parallel to the outer plate and transfixed with the same screws. The specimens were tested in a universal testing machine using a force applied to the specimen at 45 degrees to the load to provoke the most unfavourable condition, consisting of a bending moment and torsion. Both force and extension were recorded. The compound osteosynthesis with an additional intramedullary plate (group B) reached an average higher load stability. This increase of stability was not significant statistically.

Aged↗

Flexible arm splints in the control of a Lesch-Nyhan victim's finger biting and a profoundly retarded client's finger sucking.

Flexible arm splints permit the control of hand-to-mouth contacts without restricting range of motion. In the present study they effectively suppressed the self-injurious finger biting of a child with Lesch-Nyhan disease and a profoundly retarded client's stereotypic finger sucking. They appear to offer an easily applied and much less restrictive alternative to the soft-tie and tubular arm restraints in common use.

Adult↗

Long-tube gastrostomy with internal intestinal splinting: ten-year experience.

Long-tube bowel splinting at operation, with use of a gastrostomy for introduction of the tube, has many advantages in varying conditions. Results are evaluated in 79 patients undergoing operations, over a 10-year period, for first or recurrent intestinal adhesive obstruction, complicated Crohn's disease, peritonitis, ventral hernia repair, ileostomy, radiation enteritis, etc. Technique and complications are reviewed. Advantages of a recently-developed bi-lumen tube over a single-lumen tube are discussed.

Adolescent↗

Radiographic assessment of splinting bandages.

The physical attenuation of X-rays by a variety of splinting bandages was measured and compared with the subjective opinion of nine radiologists. The radiolucency of the bandages and their interference with the interpretation of bony detail on radiographs (using a radiographic knee phantom) was assessed. Plaster-of-Paris (POP) bandages produced the greatest attenuation of X-rays and the greatest interference with interpretation of bony detail. All the polyurethane resin impregnated fabric bandages produced less attenuation than POP, but variations occurred due to the fabric type and knit of the bandage. The lowest attenuation occurred in those bandages using cotton, polyester or polypropylene fabric, and in all but one instance these caused least interference in radiographic interpretation. The exception was the polyester bandage, where the coarse knit of the fabric produced a large difference in X-ray beam absorption between the air spaces and the bandage. The distracting mesh pattern on the radiograph interfered with radiographic visualization. The glass fibre bandages caused intermediate attenuation, being better than POP but not as radiolucent as the non-glass fabrics.

Bandages↗

Glass fibre versus non-glass fibre splinting bandages.

We have assessed the current range of synthetic splinting bandages, comparing glass with non-glass fabrics and plaster-of-Paris. Physical and mechanical tests have been carried out and the opinions of patients, volunteers and orthopaedic staff were recorded. Modern bandages have some better properties than standard plaster bandage but do not conform as well, are more expensive and potentially more hazardous. However, non-glass bandages are lighter, less brittle, more radiolucent and less hazardous than glass fibre bandages and are preferred by both patients and applicators.

Attitude to Health↗

Cross-arch bar splint.

This article describes the use of a round bar connector that will aid the preservation of bone support for two isolated mandibular canines when a fixed partial denture replacing the anterior teeth is contraindicated. If the removable partial denture is constructed with only the two lone-standing canines as abutments, the removable partial denture will move occlusally and gingivally during function, thereby generating forces that may cause bone loss. By the addition of a straight round bar connecting the two canine crowns, the abutments are splinted together and masticatory forces are directed along the long axes of the teeth.

Bite Force↗

Splinted vasovasostomy. Comparison of polyglycolic acid and polypropylene sutures.

An experimental study was performed comparing 6-0 polypropylene and 6-0 polyglycolic acid sutures in vasovasostomy. An indwelling entirely intraluminal splint of PE-10 tubing was used which was surgically removed three weeks postoperatively. Three months after vasovasostomy patency was determined by vasography. Eighty-five per cent patency was achieved with polyglycolic acid compared with 58 per cent patency when polypropylene was used.

Animals↗

A long-term evaluation of the mandibular Schwarz appliance and the acrylic splint expander in early mixed dentition patients.

INTRODUCTION: The aim of this prospective longitudinal clinical study was to evaluate the short-term and long-term changes in dental-arch dimensions in patients treated with either an acrylic splint rapid maxillary expander alone (RME-only) or a rapid maxillary expander combined with a mandibular removable Schwarz plate (RME-Sz) in the early mixed dentition, followed later by fixed appliances in the permanent dentition. METHODS: The dental casts of 27 RME-only patients were compared with those of 23 RME-Sz patients and 16 untreated controls (CTRL) with constricted maxillary arches at 4 times: pretreatment (T1), after expansion but before fixed appliance therapy (T2), after fixed appliance therapy (T3), and at long-term observation (T4). The mean ages for the treated groups were approximately 9 years at T1, 12 years at T2, 14 years at T3, and 20 years at T4. Arch width, arch depth, arch perimeter, and molar angulation were assessed in all subjects at all observation times. T1-T2, T2-T3, T3-T4, and T1-T4 changes were compared statistically in the treated groups with respect to the CTRL. RESULTS: Treatment with an RME-only or an RME-Sz followed by fixed appliances produced significant short-term and long-term increases in maxillary arch widths compared with the CTRL. The RME-Sz led to significantly more favorable results than the RME-only protocol: (1) significantly greater increases in the transverse width of the mandibular arch and mandibular arch perimeter in the long term, and (2) uprighting of the mandibular posterior teeth buccally, thus allowing for an amount of maxillary expansion that was clinically effective for the correction of moderate tooth size-arch size discrepancies. In the overall observation interval, the significant increases in maxillary and mandibular arch perimeters in the RME-Sz group were 3.8 and 3.7 mm, respectively, when compared with the CTRL. The RME-only protocol produced modest long-term increases in maxillary arch perimeter (2.6 mm); the average long-term increase in mandibular arch perimeter (2.0 mm) in the RME-only group was not statistically significant. CONCLUSIONS: The RME-Sz led to significantly more favorable results than the RME-only protocol.

Analysis of Variance↗

A simple and effective method of preventing inadvertent occlusion of chest tube drains: the corrugated tubing splint.

Inadvertent occlusion of tube thoracostomy drains by normal patient positioning can be not only a nuisance but also a potentially life-threatening problem. A method of splinting the pliable chest tube drains by using corrugated ventilator circuit tubing is described. This relatively simple and quick technique can help to prevent this undesired and potentially dangerous occlusion of chest tube drains.

Chest Tubes↗

Overuse injuries: tendinopathies, stress fractures, compartment syndrome, and shin splints.

Approximately 50% of all sports injuries are secondary to overuse and result from repetitive microtrauma that causes local tissue damage. Injuries are most likely with changes in mode, intensity, or duration of training and can accumulate before symptoms appear. Intrinsic factors contributing to injuries are individual bio-mechanical abnormalities such as malalignments, muscle imbalance, inflexibility, weakness, and instability. Contributing extrinsic (avoidable) factors include poor technique, improper equipment, and improper changes in duration or frequency of activity. Injuries are often related to biomechanical abnormalities removed from the specific injury site, requiring evaluation of the entire kinetic chain. This article discusses common overuse injuries of the lower leg, ankle, and foot: tendinopathies, stress fractures, chronic exertional compartment syndrome, and shin splints.

Achilles Tendon↗

A 5-year prospective randomized clinical trial on the influence of splinted and unsplinted oral implants retaining a mandibular overdenture: prosthetic aspects and patient satisfaction.

Prosthetic outcome and patient satisfaction were evaluated in order to investigate whether there is a need or advantage to splint two implants in the mandible retaining a hinging overdenture. This study included 36 fully edentulous patients randomly divided into three groups according to the attachment system they received: magnets, ball attachments or straight bars (reference group). None of the implants failed during the whole observation period in any of the groups. After 5 years of observation, the Bar group presented the highest retention capacity and the least prosthetic complications but revealed more mucositis and gingival hyperplasia. Patient satisfaction rated similar for all groups although the Magnet group showed lower retention forces. All patients would repeat the same treatment even though the majority of the Magnet group would prefer a more retentive solution because of limited denture stability.

Adult↗

Long-term survival characteristics of 832 resin-retained bridges and splints provided in a post-graduate teaching hospital between 1978 and 1993.

The clinical performance of 832 resin-retained bridges and splints provided in the adult fixed prosthodontic clinic of a post-graduate teaching hospital was reviewed. Recall data was available for 58.4% of cases and the median survival was 7 years and 10 months. Analysis of clinical variables influencing survival revealed that the design and retainer coverage were significant factors. The experience of the operator carrying out treatment also had a pronounced effect which was not readily explained in terms of the distribution of other significant factors. Resin-retained restorations made with minimal tooth preparation are shown to be capable of extended clinical service and their failure rarely resulted in adverse consequences for the patient. Patient satisfaction with their treatment was reportedly high.

Adolescent↗

The pontic-splinted procedure for tooth and denture base additions in denture repair.

Various methods for adding teeth to existing dentures have been used clinically. Although a direct, single-tooth addition method saves time, it often is difficult to achieve an esthetic appearance when adding several missing anterior teeth with this technique. Indirectly adding teeth may achieve a better esthetic result, but this method is time-consuming. This article describes the pontic-splinted procedure, an indirect method for replacing several anterior teeth and part of the denture base that can save time and, at the same time, help the clinician achieve acceptable esthetics.

Acrylic Resins↗

A comparison of the Twin Block and Herbst mandibular advancement splints in the treatment of patients with obstructive sleep apnoea: a prospective study.

This prospective, randomized, crossover study of 16 patients with obstructive sleep apnoea (OSA) [12 males, four females; median body mass index (BMI) 29.2 kg/m(2) (range 23.8-51.1); median age 44.8 years (range 24.0-68.4)] analysed the efficacy of the Twin Block (TB) in relation to the Herbst appliance as a mandibular advancement splint (MAS). Each subject was fitted with a TB and Herbst MAS in a random order with a washout period of 2 weeks between appliances. Once each patient was subjectively happy with the performance of each appliance, questionnaires and a visual analogue scale (VAS) were used to determine differences in snoring, daytime sleepiness, quality of life, side-effects of the appliances and patient preference. All patients underwent overnight domiciliary sleep recordings prior to and after fitting each appliance in order to objectively assess sleep quality in terms of the apnoea-hypopnoea index (AHI), snoring frequency and arterial oxygen saturation. The results suggested that there was no difference in the treatment performance of the TB and Herbst MAS for AHI (P = 0.71), snoring frequency (P = 0.49), arterial blood oxygen saturation (P = 0.97), quality of life and side-effects. The Herbst MAS proved to be the more effective appliance for reducing daytime sleepiness (P = 0.04) and was the more popular appliance among the patients. Side-effects with both appliances were minor and improved in the longer term. The TB MAS represents a viable alternative to the Herbst MAS in the treatment of patients with OSA.

Adult↗