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[Periodontosis].

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Climacteric↗

Treating dental disharmony with mixed media.

The art of designing a new smile often involves more than one cosmetic dental procedure. It is not uncommon to combine media such as tooth whitening with porcelain veneers and crowns to create an entirely new smile. To maintain dental harmony, it is paramount that media are indistinguishable from each other and are consistent with the existing dentition.

Crowns↗

Safety profile of Colgate Platinum Professional Toothwhitening System.

Colgate Platinum, a professional tooth-whitening paste containing 10% urea peroxide as the active ingredient, was evaluated for potential acute oral toxicity, genotoxicity, and irritation to oral mucosa. Oral administration to rats of a single dose of 5 g/kg of Colgate Platinum did not induce any adverse effects. Colgate Platinum was not mutagenic in Ames/Salmonella Plate Incorporation assay and did not induce primary DNA damage in the bone marrow hematopoietic cells of rats that were given oral doses of up to 1 g/kg for 5 consecutive days. Results of the oral mucosa irritation study in rats indicated that Colgate Platinum did not induce damage to soft and hard tissues of oral cavity after repeated applications for 28 days. Collectively, the data from these studies document the safety of the product for the intended use.

Animals↗

Effects of Colgate Platinum Professional Toothwhitening System on microhardness of enamel, dentin, and composite resins.

The purpose of this study was to evaluate the effect of Colgate Platinum Professional Toothwhitening System on the microhardness of enamel, dentin, and two composite resins. This in vitro study replicated conditions in the oral cavity and followed the prescribed procedure for whitening teeth. The results of this study showed no significant differences in the microhardness of the control and treated teeth or the composite restorations tested. This indicates that the use of Colgate Platinum will not soften teeth or the composite restoratives studied.

Carbamide Peroxide↗

Whiteners.

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American Dental Association↗