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At least 1,243 records · Page 69Linked to original sources
PubMed2004

[Evidence-based practice. Part 1: Origins, definitions, critiques, obstacles, advantages and impact].

The increasing popularity of evidence-based practice (EBP) requires that nurses take a stand regarding this type of practice. This positioning rests on knowledge of EBP, however this notion varies by discipline and many definitions exist even within the nursing discipline. An improved understanding of the basic tenets of this type of practice is thus essential. This first, of a series of two articles describes the origin of EBP as well as various definitions, it also presents the major criticisms raised and takes a look at the impact of the increased tendency towards EBP on professional practice.

Diffusion of Innovation↗
PubMedDate not supplied

Overcoming obstacles in aesthetic implant reconstruction.

As experience with implants has grown, the aesthetic expectations of both dentists and patients has increased. Controlled placement techniques can benefit the aesthetic result, but anatomic constraints and procedural limitations may prevent ideal implant placement. This article reviews guidelines to proper placement of implants and presents surgical and restorative approaches to correction of improper positioning. The key to a successful, aesthetically pleasing reconstruction lies in careful case planning and communication.

Dental Implantation, Endosseous↗
PubMed1992

Report on family medicine in the Nicaraguan Revolution: advances and obstacles 1985-1991.

Family practice, a well-developed specialty in the United States, is now finding application in Third World settings. The development of family medicine in Nicaragua is described within the historical context of the Nicaraguan Revolution and global developments in primary health care. Difficulties encountered and adaptations necessary for developing countries are discussed within the context of international models of primary health care.

Civil Disorders↗
PubMedDate not supplied

Ludwik Hirszfeld Memorial Lecture: HIV-1 reservoirs: major molecular obstacles to viral eradication.

Over the last 18 years of study in one of our laboratories, we have observed the development of residual disease and latent reservoirs as major problems in the long-term therapy of HIV-1-infected individuals on highly active antiretroviral therapy (HAART). It was shown in the early 1990 's that HAART, as it is presently configured, is unlikely to lead to viral eradication due to several mechanisms of viral persistence. The two general mechanisms involved with persistence during HAART include low-level residual, cryptic replication and proviral latently-infected cells. As such, these are key areas of potential studyfor depletion and, hopefully in the future, eradication of residual disease in patients on suppressive HAART. To deplete these residual disease mechanisms will require multipronged approaches. These will include induction of HIV-1 latent proviruses, suppression of residual viral replication and destruction of long-lived cellular sanctuaries, such astissue-bound macrophages.

Acquired Immunodeficiency Syndrome↗