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At least 127 records · Page 7Linked to original sources

Mite allergen exposure, sensitisation and clinical symptoms in Valdivia, Chile.

One hundred consecutive asthmatic paediatric patients were evaluated and skin tested with a battery of skin prick test reagents, including 8 different standardized house dust mite extracts. Asthma severity was graded according to the Global Initiative for Asthma (GINA) document in mild persistent (52 patients), moderate persistent (39) and severe persistent (9). Sixty patients had asthma and allergic rhinitis, 12 asthma and eczema, and 8 asthma, allergic rhinitis and eczema. The patient population was divided into 2 different socioeconomic groups (50 patients per group) based on a standardized, validated questionnaire. A dust sample was collected with an adapted vacuum cleaner from the mattress of each patient and analysed for Der p 1, Der f 1 and Der p 2 allergen content using monoclonal antibodies. Eighty patients were skin test positive to at least one mite species. All positive skin test patients were positive to Dermatophagoides pteronyssinus, 99% to D. farinae, 92% to Euroglyphus maynei, 80% to Lepidoglyphus destructor, 73% to Tyrophagus putrescientae, 72% to Blomia tropicalis; 70% to Acarus siro and 68% to Chortoglyphus arcuatus. All patients with severe persistent asthma had a positive skin test to mites, 85% in the moderate group, and 73% in the mild group (p < 0.01). 95% of patients with asthma and allergic rhinitis had a positive skin test to mites, 92% of patients with asthma and eczema and 100% of patients with asthma, allergic rhinitis and eczema; (p < 0.01). Mean Der p 1, Der f 1 and Der p 2 allergen concentrations were 18.3, 0.6 and 5.6 microg/g of mattress dust, respectively. Mean Der p 1 allergen levels in the middle-low socioeconomic group were significantly higher than in the middle high group (p < 0.01). There is a high rate of allergic sensitisation among pediatric asthmatic patients in Chile. More than one species are implicated, although sensitisation and exposure to D. pteronyssinus predominates. Mite allergic patients are exposed to high mite allergen concentrations, exceeding previously established risk levels for sensitisation and symptoms.

Adolescent↗

Skin cross-reactivity between Dermatophagoides pteronyssinus and storage mites in atopic children.

In our environment, some children with allergic respiratory pathology do not have as favorable an evolution as expected after three years of immunotherapy with D. pteronyssinus extracts. We believe this is due to the existence of other mites whose antigenic determinants are not present in D. pteronyssinus. The purpose of the present study was to evaluate skin cross-reactivity between Dermatophagoides and storage mites in children with bronchial asthma. Fifty patients were chosen, with a mean age of 7.78 +/- 2.98 years and a range of 3-14 years. There were 38 boys (76%) and 12 girls (24%) with rhinitis and bronchial asthma. All patients had skin tests and prick tests with the following extracts performed on them: house dust (HD), Dermatophagoides farinae (DFA), Dermatophagoides pteronyssinus (DPT), Acarus siro (AS), Glycyphagus domesticus (GD), Lepidoglyphus destructor (LD), Tyrophagus putrescentiae (TP), with negative and positive controls. The areas of the papulae were evaluated in crosses, according to the size of the histamine and using computerized papulometry, using the Kurta series one graphic tablet with one resolution of 200 points per inch. The data were processed with the "Image-pro" analysis image program. The following conclusions were obtained from our study: 1) No case of skin sensitization to storage mites was found in any of our 50 patients, without house dust and/or Dermatophagoides mites also being present. 2) The greatest skin response with regard to histamine was found for DFA (52%), DPT (44%), HD (22%), GD (10%), AS (4%) and GF (2%).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

[Arthropods found on European beaver (Castor fiber L.) in Poland].

In July 1988, arthropods from 6 Castor fiber were collected at Popielno near Ruciane. Schizocarpus numerosus Dub., S. fedjushini Dub., S. brachyurus Dub. are new to the fauna of Poland. Ixodes hexagonus Leach (larvae, nymphs, females) is especially numerous. Under-development of the coxa and trochanter of the third left leg was noted in one female. Moreover, Acarus farris (Oud.), Cunaxoides kielczewskii Mich. and unidentified female of the Phytoseiidae were obtained. Cunaxid mites have not been collected hitherto from mammals. At the present time in Poland, 8 species (including Platypsyllus castoris Rit.) of arthropods are found on C. fiber.

Animals↗

[Sensitization to granary mites in patients with allergic diseases].

As many as 71 patients selected from a group of 550 patients suffering from allergic diseases, sensitized to the house dust mites Dermatophagoides pteronyssinus were examined. A study was made of the presence of allergen-specific IgE antibodies against house dust mites, storage mites (7 species altogether) using allergenic discs and commercial kits RAST (Pharmacia, Sweden). The group under examination mostly manifested sensitization to the house dust mites: Dermatophagoides ferinae (80%), Euroglyphus maynei (55%); storage mites: Acarus siro (45%), Lepidoglyphus destructor (35%). The latter one possesses the most powerful allergenic properties as compared to the acaroid mites of other types. The elevated sensitivity to storage mites is encountered among adults and children living both in Moscow and other regions (urban and rural). The problem of sensitization to storage mites in the USSR mandates thorough studies, which will enable the treatment and diagnostic agents to be designed and introduced into practice.

Animals↗

Dermatophagoides and storage mites: statistical analysis of RAST results.

R.I.A. dosages of specific IgE antibodies to Dermatophagoides pteronyssinus, Dermatophagoides farinae (house dust mites), Acarus siro, Lepidoglyphus destructor, and Tyrophagus putrescentiae (storage mites) in 467 unselected patients were statistically analyzed. A significant noncorrelation between specific IgE antibodies to storage mites and those to house dust mites has been found, suggesting that storage mites have their own allergenic specificity.

Allergens↗

[Human pulmonary ascariasis in Anhui Province: an epidemiological survey].

924 subjects, 542 males and 382 females working in grainstoring, or herb-storing, from different parts of Anhui Province were examined for the possible existence of pulmonary acariasis. 49 cases(5.3%), 31 males and 18 females, were found positive for mites in their sputum. 83.7% of the sufferers aged 16-45. 22 out of the 22 out of the 49 sufferers developed a marked eosinophilia ranging from 4% to 48% and a count of 320-5,050/mm3, whereas X-ray films revealed varied degrees of widening lung hilum shadow with increased and disordered lung markings. In some cases, the chest-film showed a lot of scattered nodular shadows 1-5 mm in diameter in the lung lobes. The symptoms presented were cough, expectoration, depression in the chest, restlessness, low fever, asthma, hemoptysis, etc. 10 species of mites were found in the sputum of the 49 sufferers, i.e. Acarus siro, Tyrophagus putreseltiae, Aleuroglyphus ovatus, Caloglyphus berlesei, C. myoophagus, Dermatophagoides farinae, D. pteronyssinus, Euroglyphus maynei, Tarsonemus granarius, Cheyletus eruditus.

Adolescent↗

[Pathology caused by acari].

This report concerns the observations the Authors have been carrying out for over twelve years in Sardinia; they regard the sensitization to house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) and to storage mites (Acarus siro, Glycyphagus domesticus, Lepidoglyphus destructor, Tyrophagus putrescentiae) and are been obtained with: 1) skin tests with mite extracts; 2) RadioAllergoSorbentTest (RAST) for specific IgE and IgG; 3) mite exposure in homes and mite analysis; 4) hyposensitisation with personal time-lag vaccines holding one or more "storage" or "house dust" mites. They are been prepared on the ground of RAST, skin tests, clinical symptomatology and environmental exposure to mites; 5) clinical control after therapy with vaccines for a period of five till to ten years. The Authors obtained unusual results.

Acari↗

[A particular type of self management of asthma in childhood. The Neapolis project].

The goal of this study was the observations of the comportment of 5 groups of asthmatic children, followed either with weekly ambulatory control of functional respiratory capacity or with daily control of PEF at home by Asses Peak Flow. The five groups were formed: group A (10 allergic subjects either to aeroallergens or to foods, with exclusion of food allergens from diet); group 1B (similar group, which executed the food allergen's exclusion with weekly reintroduction of one food allergen with protection of DSCG); group 1C (allergic children either to aeroallergens or to food, who non executed the withdrawal of food allergens from diet: Control group); 2A group (allergic children only to aeroallergens, which executed only the acarus' removal from ambient); 2B group (allergic only to foods, which executed the removal of food allergens from diet). The control's results showed near to 0, for pathology, the group 2B, then the group 1A, then 2A and 1B; the 1C group showed heavy asthmatic condition and employed beta 2-drugs and cortisonics.

Asthma↗

Skin and serum reactivity to some storage mites in children sensitive to Dermatophagoides pteronyssinus.

The incidence of skin test and RAST positivity for Dermatophagoides farinae and storage mites (Glycyphagus privatus, Lepidoglyphus destructor, Tyrophagus putrescentiae, Acarus siro, and Gohieria fusca) have been evaluated in children with bronchial asthma and positive prick test to Dermatophagoides pteronyssinus. The storage mite with highest incidence of skin and RAST positivity was Gohieria fusca, which caused a positive response in more than 50% of the children evaluated. This antigen appears to possess allergenic determinants not present in Dermatophagoides pteronyssinus. The sensitivity to this antigen might be considered in house dust mite-allergic children who do not improve after specific immunotherapy with Dermatophagoides pteronyssinus extracts.

Adolescent↗

Sensitization to storage mites and other work-related and common allergens among Finnish dairy farmers.

Skin-tests with the prick technique were made on 121 dairy farmers with allergic rhinitis and/or asthma (symptomatic subjects), 64 dairy farmers without respiratory symptoms (asymptomatic subjects), and 26 non-farming controls. The antigen panel consisted of the storage mites Acarus siro, Lepidoglyphus destructor, and Tyrophagus putrescentiae, as well as other work-related allergens (cereal grains, animal epithelia, fungi and yeasts), and common allergens (house dust mite, pollens). Mean areas of weals formed by individual allergens were adjusted by analysis of covariance for age, sex, and atopic background (past or present atopic dermatitis including infantile eczema). Adjusted mean weal areas for almost all allergens, except pollens and few other allergens, were significantly larger in farmers than in non-farming controls. In contrast, only skin reactions to cow dander, to a non-dialyzed crude preparation of fodder yeast Candida utilis, and to Candida albicans distinguished symptomatic subjects from asymptomatic ones. Stepwise discriminant analysis, in which reactions to all allergens as well as age, sex, and atopy were taken into account simultaneously, revealed that reactions to a dialysed preparation of fodder yeast best distinguished symptomatic farmers from asymptomatic ones. C. utilis and C. albicans may be cross-reactive. The results imply that skin tests alone are of limited value in the search for work-related causes of rhinitis or asthma among dairy farmers. Our study confirms the importance of cow dander as an occupational allergen in dairy farming. Fodder yeast seems to be another important occupational sensitizer.

Agricultural Workers' Diseases↗

[Childhood acropustulosis. A study of 10 cases].

Ten cases of infantile acropustulosis were studied clinically, in laboratory and histopathologically. There was no racial predominance. In most of the cases the lesions started in the first 6 months of life and were located mainly on the feet severe itching. Was a constant symptom. Laboratory studies were negative for fungus, bacteria and acarus. Atopy was found in 20% of the cases and 30% of the families. Blood eosinophiles was found in 70% of the lesions.

Dapsone↗

[Mites (Acaridae) as a possible cause of upper respiratory diseases in grain elevator operators].

The results of qualitative and quantitative investigations on the occurrence of mites (Acaridida) in the elevator have been presented. 117 samples coming from reloaded grain material (wheat, maize, barley, granulate), from the dust occurring and depositing during reloading, as well as from the surface layer of soil around the elevator have been tested. The percent of samples affected by mites ranged from 12.5% in the reloaded material to 87.8% in the soil around the elevator. Populations of different species have been found (Acarus sp., Tyrophagus sp., Glycyphagus sp., Tyreophagus sp., Dermatophagoides sp., and others). They not only affect the grain products stored but also act as allergens affecting those occupationally exposed in the elevator and its environment.

Agricultural Workers' Diseases↗

[1st report of an intermediary host of Moniezia sp in Cuba].

The determination of an oribatid belonging to the Scheloribates genus as an intermediary host of the Moniezia sp. helminth is reported for the first time in Cuba. Photographs and measurements taken during the infecting larval state of Moniezia (cisticercoid) found are included, such as it is observed because of transparency in the interior of acarus and drew out from the Latter for its better identification.

Acari↗

Immediate type hypersensitivity in dogs induced by storage mites.

Results of intradermal skin tests on 53 dogs, employing storage mite extracts as antigen, indicated that storage mite allergy is fairly common. Only four of 29 dogs exhibiting no allergic symptoms showed skin reactions to the most common storage mite, Acarus siro, whereas 18 out of 24 dogs with symptoms assumed to be associated with allergy showed such reactions. The passive cutaneous transfer test revealed that an immediate type hypersensitivity reaction was involved.

Animals↗

Controlled activity mite vaccines for 'barn allergy'.

Three species of mites, Tyrophagus longior, Glyciphagus destructor, and Acarus farris have been isolated from the dust of barns of farms in Orkney. The mites were cultured in amount sufficient for the production of bulk extracts. These were then tested by skin prick in a population of 30 inhabitants of Orkney and potency was assigned in units of biologic activity. The concentrations of the bulk extracts from the different species were adjusted to the same biologic potency and then used to make delayed-release vaccines for injection therapy and aqueous solutions for provocation tests and therapy by the nasal route. The vaccines were then administered by injection to nine subjects at weekly intervals over a period of 2 months. Assessment by questionnaire suggested that there was a significant improvement in the symptoms of eight of the nine subjects. A course of nasal therapy with the aqueous solutions produced no improvement in four out of five subjects.

Adult↗

Storage mites as a cause of bronchial asthma in Denmark.

From October 1982 to July 1983, 133 consecutive patients complaining of allergic symptoms were prick-tested with three storage mites (Acarus siro, Lepidoglyphus destructor, Tyrophagus putrescentiae) and two housedust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae). A total of 60 patients (45%) had a positive prick-test for one or more of the storage mites. A mutual positive correlation was found between the prick-test results for the two house-dust mites as well as for the three storage mites. No significant correlation was found between house-dust mites and storage mites. Four cases of allergy to storage mites are presented. The diagnosis of storage mite allergy was based on the clinical history, prick-test, bronchial provocation test and the finding of storage mites in the environment of the patient. Our study suggests that allergies to storage mites could be rather frequent in the Danish population.

Adult↗

[Unusual retention cyst of lower lid (author's transl)].

A 70-year-old woman presented with an unusual retention cyst of right lowerlid border. Histological findings: epiderm cyst of atheroma type. There is no relapse after operation. Inflammatory occlusion of Zeiss- or Meibom-sebaceous gland by saprophytic mites (Acarus siro, Demodex folliculorum) is discussed.

Aged↗

House dust mites in Switzerland. III. Allergenic properties of the mites.

The allergenic properties of the nine mite species prevalent in the house dust of northwestern Switzerland (Basel and surroundings) were studies. For the preparation of mite extracts, the average weight of each species was first determined and then the number per culture glass counted. Thus the extracts were prepared according to the weight of the mites. They were tested on 115 patients with ashma and/or rhinitis. Tests with patients own house dust and with a human dander/yeast mixture, which served as culture medium for the mites, were carried out simultaneously. Test results were either positive or negative for all substances in 93 patients (80 per cent). Dermatophagoides pteronyssinus, D. farinae and Euroglyphus maynei caused the most frequent and most severe reactions. The species Glycyphagus destructor, G. privatus, Chortoglyphus arcuatus, Gohieria fusca, Tyrophagus putrescentiae and Acarus siro seem to play a less important role, if any, in house dust allergies.

Adolescent↗