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At least 127 records · Page 7Linked to original sources
PubMed1994

Effects of lindane exposure on rainbow trout (Oncorhynchus mykiss) immunity. I. Effect of lindane on antibody-secreting cells (ASC) measured by ELISPOT assay.

Yersinia ruckeri vaccine was injected in rainbow trout 7 days after ip contamination with 10, 50, or 100 mg lindane per kilogram body weight. The antibody-secreting cells measured by ELISPOT assay were affected by the insecticide, slightly for 10 mg and strongly for higher concentrations. Consequently the antibody production in sera, measured by agglutination, was suppressed.

Animals↗
PubMed1982

Unidirectional uptake of L-alanine and L-serine by system ASC in the basolateral membrane of cat salivary epithelium. Selective inhibition of rapid alanine metabolism by aminooxyacetate.

Unidirectional influx of L-alanine and L-serine across the basolateral membrane of cat salivary epithelium was investigated in perfused submandibular glands using a rapid (less than 30 s) paired-tracer dilution technique. (Bustamante, J.C., Mann, G.E. and Yudilevich, D.L. (1981) J. Physiol. 313, 65-79). High uptakes were measured for both neutral amino acids, however, only the uptake of L-alanine was followed by an immediate tracer efflux into the circulation. Aminooxyacetate, an inhibitor of alanine aminotransferase, completely inhibited this efflux and glandular pyruvate production. These results demonstrate that in assessing unidirectional amino acid uptake, the influence of metabolism should be considered even during short intervals of measurement.

Acetates↗
PubMed1991

Correlation of in vivo and in vitro performance of adhesive restorative materials: a report of the ASC MD156 Task Group on Test Methods for the Adhesion of Restorative Materials.

Before a standard designed to test the adhesion of adhesive restorative materials can be accepted, it is necessary to identify those parameters which are of clinical relevance and which can be studied under in vitro testing conditions. The goal of this report has been to identify information related to how dentinal fluid, intra-tubular pressure, polymerization shrinkage, cavity preparation, cavity shape, placement technique, curing method, tooth age, environmental conditions, masticatory forces, thermal cycling, and microleakage influence the bond strength++ of adhesive restorative materials. This review is also intended to function both as an information base of past experimental data as well as a source of guidance for further, needed research.

American Dental Association↗
PubMed1994

Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.

The 3,6-dideoxyhexoses are found in the lipopolysaccharides of gram-negative bacteria, where they have been shown to be the dominant antigenic determinants. Of the five 3,6-dideoxyhexoses known to occur naturally, four have been found in various strains of Salmonella enterica (abequose, tyvelose, paratose, and colitose) and all five, including ascarylose, are present among the serotypes of Yersinia pseudotuberculosis. Although there exists one report of the cloning of the rfb region harboring the abequose biosynthetic genes from Y. pseudotuberculosis serogroup HA, the detailed genetic principles underlying a 3,6-dideoxyhexose polymorphism in Y. pseudotuberculosis have not been addressed. To extend the available information on the genes responsible for 3,6-dideoxyhexose formation in Yersinia spp. and facilitate a comparison with the established rfb (O antigen) cluster of Salmonella spp., we report the production of three overlapping clones containing the entire gene cluster required for CDP-ascarylose biosynthesis. On the basis of a detailed sequence analysis, the implications regarding 3,6-dideoxyhexose polymorphism among Salmonella and Yersinia spp. are discussed. In addition, the functional cloning of this region has allowed the expression of Ep (alpha-D-glucose cytidylyltransferase), Eod (CDP-D-glucose 4,6-dehydratase), E1 (CDP-6-deoxy-L-threo-D-glycero-4- hexulose-3-dehydrase), E3 (CDP-6-deoxy-delta 3,4-glucoseen reductase), Eep (CDP-3,6-dideoxy-D-glycero-D- glycero-4-hexulose-5-epimerase), and Ered (CDP-3,6-dideoxy-L-glycero-D-glycero-4-hexulose-4-reductase), facilitating future mechanistic studies of this intriguing biosynthetic pathway.

Amino Acid Sequence↗