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Calcium-channel blockers and advanced cardiac life support.

Calcium channel-blocking drugs have potent antiarrhythmic and antianginal effects and in addition may reduce the extent of cellular injury after anoxia/ischemia. Verapamil is the treatment of choice (90% effective) for uncomplicated episodes of paroxysmal supraventricular tachycardia. All three calcium-channel blockers available, diltiazem, nifedipine, and verapamil, can reduce the frequency of angina occurring both at rest and with exertion. Calcium may mediate several cytotoxic events during the reperfusion period after prolonged ischemia that lead to irreversible cell injury. There is experimental evidence that calcium-channel blockers may reduce the cellular influx of calcium after ischemia and reperfusion, and thereby attenuate cerebral and myocardial injury, although most studies have failed to show benefit of treatment unless the drug is administered before the onset of ischemia. Most trials using calcium-channel blockers in the setting of acute myocardial infarction have failed to show a benefit of treatment. The safety and efficacy of calcium-channel blockers have yet to be shown in controlled studies of human resuscitation, although the potential for such treatment, if it is effective in attenuating myocardial cerebral cellular injury, could be enormous.

Brain Ischemia↗

Assessment of the proficiency of the surgeon in providing basic and advanced cardiac life support.

The results of this study demonstrate a need for further improvement in the ability of selected surgeons to manage competently a cardiac arrest according to current AHA guidelines. The importance of formal training is demonstrated by the fact that prior BCLS or ACLS certification increased the likelihood that proper resuscitative measures will be used by the surgeon. In particular, greater emphasis should be placed upon standard dysrhythmia treatment protocols since we have shown that the level of the expertise of the surgeon in this area is lowest. Improvement in resuscitation skills should enhance the ability of the surgeon to treat effectively patients who are critically ill.

Arrhythmias, Cardiac↗

Cardiac arrest during pregnancy: maternal-fetal physiology and advanced cardiac life support for the obstetric patient.

Although cardiac arrest in pregnancy is rare, all members of the healthcare team who care for pregnant women should be aware of the maternal adaptations of pregnancy. Also, more women with preexisting medical conditions are attempting pregnancy. Perinatal nurses, especially those practicing in level III (high-risk) perinatal centers should be trained in dysrhythmia recognition and ACLS protocols. Rapid intervention sometimes can save two lives.

Female↗

[Venous access and methods of drug application in ACLS (Advanced Cardiac Life Support)].

After initiation of cardiopulmonary resuscitation [CPR] with ventilation, chest compression and defibrillation when necessary, venous access, which allows administration of drugs and fluids, is the next measure. A large diameter peripheral vein should be the first choice and should be cannulated with a plastic catheter. If this is delayed or impossible, alternative routes such as central iv lines, intraosseous infusion or endobronchial drug administration should be considered.

Catheterization, Peripheral↗

An intelligent learning environment for advanced cardiac life support.

Resuscitation from clinical cardiac arrest is complex and often takes several years to learn. This paper describes an intelligent simulation-based tutor for ACLS which increases students' opportunity to practice before, during and after the ACLS course, thus bridging the gap between studying theory and didactic textbook material and working with patients. Sophisticated reasoning about student performance, compared to an expert model, distinguishes this system from other computerized instruction systems. Intelligence in the tutor allows the system to make the simulation dynamically adaptive to focus on areas where the student's learning needs are greatest. A formative evaluation with two classes of fourth year medical students suggested that the tutor was helpful, realistic and effective. Positive reactions and strong student involvement with the simulation suggest that this simulation-based tutor may improve learning and retention while decreasing anxiety for most students.

Computer Simulation↗

Army nurses' knowledge base for determining triage categories in a mass casualty.

The timing, location, and participants in a mass casualty scenario cannot be predicted. Nurses may be involved in performing triage, yet there is no published documentation of military nurses' ability to triage. A prospective design was used to describe 82 Army nurses' knowledge base related to designating triage categories for patients during a mass causality, examining the relationships among their education and experience as evaluated by The Darnall Mass Casualty Triage Test and Demographic Data Form. The most significant areas associated with higher scores on the Triage Test were: completion of Advanced Cardiac Life Support, advanced certification as a Certified Registered Nurse Anesthetists, Certified Emergency Nurse, or Critical Care Registered Nurse, and attendance to the Medical Management of Nuclear Weapons Course. An improved average score for nurses overall was also noted when compared with previous work with the Darnall MASCAL Triage Test.

Analysis of Variance↗