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Results for “Biomedical Enhancement”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

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At least 127 records · Page 7Linked to original sources
PubMed2002

Optimal pulse-inversion imaging for microsphere contrast agents.

Microbubbles are used as contrast agents because they scatter incident ultrasound (US) efficiently. Pulse-inversion imaging makes use of the asymmetrical difference in response of a bubble to an US pulse and its symmetrical opposite to obtain improved contrast. In this theoretical work, the principle of pulse-inversion imaging is expanded upon by finding the optimal pulse shape to maximize the signal from a bubble. Given a limit on driving intensity, a suitable norm of the bubble response is maximized using optimal control theory to identify the proper pulse/antipulse driving protocol for a single bubble. The optimal pulse yields a several-fold increase in the normed response over the best sinusoidal pulse of the same driving intensity. It was found that the optimal driving for a single bubble also maximizes the nonlinear response of the cloud if its mean bubble size is the same as that of the single bubble.

Biomedical Enhancement↗
PubMed2005

International perspectives on engaging the public in neuroethics.

With an ever-increasing understanding of the brain mechanisms associated with core human attributes and values, there is an increasing public interest in the results of neuroscience research and the ways in which that new knowledge will be used. Here, we present perspectives on engaging the public on these issues on an international scale, the role of the media, and prospects for the new field of neuroethics as both a focus and a driver of these efforts.

Bioethical Issues↗
PubMed1990

An evolving agenda for the AAMC's second century.

The author presents a discussion of current problems in health care delivery and considers potential solutions. He notes that in the United States there is a wide disparity in health care status between the white population and the poor and minority communities, and that this disparity exists in virtually every health care category. Inadequate access to health care services, perpetuated by the high cost of health care, is part of the problem. The author analyzes many legislative and administrative steps that have been taken to address these issues, and many more that should be carefully examined. More emphasis on health promotion and disease prevention is vital. Another solution is to further enhance the biomedical research enterprise and work to prepare the regulatory system to quickly, safely, and effectively infuse this knowledge into the health care delivery system. Another solution is for physicians to be adequately prepared for this practice of medicine in the years to come.

Delivery of Health Care↗
PubMed1999

Understanding health behavior and speaking out on the uninsured: two leadership opportunities.

The author reviews the growth of managed care and its transforming effect on academic medical centers. He then maintains that in this time of fundamental changes and stress, academic medical centers should not only attend to the organization and financing of the clinical enterprise and the enhancement of biomedical research capacity, but also ask how academic medicine can live up to the unique opportunities and responsibilities it has been entrusted with to improve the health of the public, particularly in two neglected areas. First, if the nation does not expand the research agenda to include social and behavioral factors involved in preventable causes of morbidity and mortality, it will fail to maximize the dividends from the generous public investment in research and fail to learn how to promote healthy personal behavior. Academic medicine can promote such behavior by increasing the science base of prevention and translating into action what is already known, including how to market that knowledge so the public will respond. Second, the number of the medically uninsured is increasing; the largest percentage are the working poor. It is becoming more difficult for teaching hospitals to continue providing a third of the nation's uncompensated care. The author shares a variety of statistics about the uninsured and their care, and maintains that academic medicine, which has been entrusted with the health of the public, can declare that the high number of the uninsured is not acceptable and is a dangerous side effect of the U.S. health care system that must be treated. Doing so will also set an example to medical students and trainees that medicine's responsibility is to all Americans.

Academic Medical Centers↗
PubMed1993

Assistive technology policy: a road to independence for individuals with disabilities.

This article identifies and analyzes equity issues in assistive technology policy for adults with disabilities in the United States and makes recommendations for further research and advocacy. The following equity issues are considered: (a) who has access to assistive technology, (b) which technology is available, (c) who decides on the technology, and (d) who controls or determines the allocation of assistive technology. The discussion considers the role of stereotyping and discrimination in policy-making and how these affect equity. There is a need to rethink the concepts of normal and abnormal, and to reformulate policy more on the basis of the values of empowerment, independence, and community integration.

Adult↗
PubMed2006

Use of botanicals in food supplements. Regulatory scope, scientific risk assessment and claim substantiation. 2005.

BACKGROUND/AIMS: In the European Union, an elaborate legal framework regulates botanical products both under food and medicinal law. The decision as to which legal framework applies to an individual product may differ between the Member States. In the case of botanical food supplements, all food law provisions apply to their manufacturing, composition and marketing, including the new claims legislation. METHODS: Elements from EU and national law, scientific and other publications are brought together to investigate how to clarify the differentiation between the use of botanicals for medicinal and health-promoting purposes on a scientific basis. RESULTS: Guidance on the safety assessment and quality evaluation of botanicals is proposed in light of the different approaches described in the scientific literature with particular attention to the concept of long-term use as an integral part of safety evaluation. Guidance on claims substantiation is also included, taking into consideration the proposed legislation, the concept of long-term experience and grading of evidence. CONCLUSIONS: A model for safety and efficacy assessment of botanical food supplements in the EU is proposed, and should be taken into consideration in the development of legislation and scientific research on botanicals.

Animals↗
PubMed2004

Science and technology integration for increased human potential and societal outcomes.

Unifying science based on the material unity of nature at the nanoscale provides a new foundation for knowledge, innovation, and integration of technology. Revolutionary and synergistic advances at the interfaces between previously separated fields of science, engineering and areas of relevance are ready to create nano-bio-info-cogno (NBIC) transforming tools. Developments in systems approach, mathematics, and computation in conjunction with NBIC allow us to understand the natural world and scientific research as closely coupled, complex, hierarchical entities. At this unique moment of scientific and technical achievement, improvement of human performance at individual and group levels, as well as development of suitable revolutionary products, becomes possible and these are primary goals for converging new technologies. NBIC addresses long-term advances in key areas of human activity, including working, learning, aging, group interaction, organizations, and human evolution ((Roco and Bainbridge, 2003)). Fundamentally new tools, technologies, and products will be integrated into individual and social human architecture. This introductory chapter of the Annals outlines research and education trends, funding activities, and the potential of development of revolutionary products and services.

Biological Evolution↗