[Bone neoplasms and their effect on the body].
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The study of 819 cases of tumors and tumor-like lesions of long tubular and flat bones and 139 cases of chronic fistulous osteomyelitis formed the basis for identification of malignant transformation-causing factors and development of measures for preventing secondary bony sarcomas.
The process of staging bone tumors is complex. The goal of staging is to define the type of tumor and its extent. Like staging for other neoplasms, it stratifies patients into groups based on prognosis and established treatment protocols. Staging is a multidisciplinary effort involving orthopedic oncologists, musculoskeletal radiologists, and orthopedic pathologists. The diagnosis is often suggested on clinical examination and review of the radiographs. The biopsy usually confirms the clinical and radiographic impression. However, biopsy is difficult and leads to errors in diagnosis in nearly 20% of cases. These errors may make limb salvage impossible and adversely affect survival. For this reason, staging and especially the biopsy should be done in the institution where definitive treatment is planned.
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