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[Neurologic symptoms and their dynamics in contusions of the spinal cord of mild and moderate severity at the level of the 1st and 2d cervical vertebrae].

The results of the study of 154 patients with an acute trauma of the cervical portion of the vertebral column showed that fractures, dislocations and fractures/dislocations of the first-second cervical vertebrae accounted for 10.4% of all the studied cases. In mild contusion of the first-second segments the leading clinical symptoms in the acute period were pareses of the arms and paralyses of hands with retained reflexes and insignificant impairments of sensitivity in fingers, i.e., the level of clinical manifestations did not correspond with the conventional segmento-metameric innervation. In the acute period of contusions of moderate severity tetraplegia is formed, which, however, does not affect the reflexes. Timely elimination of the compression helps to restore motor activity and sensitivity first in the legs and the body and later in the arms. In the long term of the injury motor activity in the arms recovers and the leading clinical symptoms become manifestations of pyramidal deficiency with insignificant sensitivity disorders in the hands and feet, predominantly of a subjective-radicular nature.

Adult↗

Fractures of the second cervical vertebra: Internal fixation by interlaminar wiring.

Fractures of the 2nd cervical vertebra are frequently undetected on initial evaluation. Tomography may be necessary to delineate the fracture. This is a report of 20 patients treated by internal fixation using interlaminar wiring. There was no operative mortality. Follow-up studies, an average of 25 months after operation, demonstrated satisfactory results and no evidence of delayed neurological deficit.

Adolescent↗

Cervical vertebrae measurements in syringomyelia.

Lateral X-rays of the cervical spine taken under standard conditions in 69 cases of syringomyelia have been measured to assess the relative sizes of the canals and bodies. One hundred and five cases without cervical spine abnormality provided controls. The expected expansion has been observed in males from C5 to C7 and in females from C3 to C7. The oddity that the expansive process seemed to come higher in females than in males has been noted by other workers. In both sexes it has been found that diminution of vertebral body size is a more consistent finding than enlargement of the canals and correlation coefficients have confirmed that enlargement of the canal appears to take place at least in part at the expense of the body. Possible factors in the enlargement are discussed. Oblique measurements taken in 57 syrinx cases and 89 controls showed the expected change caused by the view of the lower cervical vertebrae being closer to AP and pictures of the upper vertebrae being progressively closer to lateral views. There was a tendency for the bigger oblique diameters to occur in these cases with the biggest sagittal diameters and an insignificant tendency for the biggest canals to have a diminished difference between the two oblique measurements. There was no evidence that oblique measurements could be used to detect slight degrees of enlargement in cases of syringomyelia.

Adult↗

Radiographic measurement of the prevertebral soft tissue of cervical vertebrae.

The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widened soft tissue space is of diagnostic significance, diagnosis should be made on the basis of analysis of the injury history, clinical manifestation and imaging examination.

Adult↗

Laminar avulsion in a cervical vertebra.

An unusual avulsion fracture involving the lamina of a cervical vertebra, most likely due to tear of a ligamentum flavum, is described. Its radiographic features may be quite subtle. Simulation of this fracture on dried skeleton allowed a better understanding of its appearance on the standard projections, its mechanism of occurrence, and its delayed recognition on the patient's anteroposterior view. Only awareness of the existence of this type of fracture and special efforts directed toward its detection will determine its true frequency.

Adolescent↗

Hyperbrachycephaly, short face, midface hypoplasia, fusion of cervical vertebrae, radiolucent bone defects, and severe destruction of periodontium--a new syndrome: craniofaciocervical osteoglyphic dysplasia.

A patient with an unusual combination of findings, which do not fit in any of the known syndromes, is presented. The patient, a 24.5-year-old male of normal growth and intelligence, manifests craniofacial dysmorphism, radiolucencies in the skull and in the cervical vertebrae, progressive alveolar bone loss and fusion of cervical vertebrae. The young man does not exhibit any other systemic, hematological, biochemical, chromosomal or immunological abnormality, except for IgA deficiency.

Adult↗

Motion analysis of cervical vertebrae during whiplash loading.

STUDY DESIGN: The motion of each cervical vertebra during simulated rear-end car collisions was analyzed. OBJECTIVES: To clarify the mechanism of zygapophysial joint injury during whiplash loading. SUMMARY OF BACKGROUND DATA: The zygapophysial joint is the suspected origin of neck pain after rear-end car collision. However, no studies have been conducted on the mechanisms of zygapophysial joint injuries. METHODS: Ten healthy male volunteers participated in this study. Subjects sat on a sled that glided backward on inclined rails and crashed into a damper at 4 km/kr. The motion of the cervical spine was recorded using cineradiography. Each vertebra's rotational angle and the instantaneous axes of rotation of the C5-C6 motion segments were quantified. These measurements implemented the template method. RESULTS: There were three distinct patterns of cervical spine motion after impact. In the flexion-extension group, C6 rotated backward before the upper vertebrae in the early phase; thus, the cervical spine showed a flexion position (initial flexion). After C6 reached its maximum rotational angle, C5 was induced to extend. As upper motion segments went into flexion, and the lower segments into extension, the cervical spine took an S-shaped position. In this position, the C5-C6 motion segments showed an open-book motion with an upward-shifted instantaneous axis of rotation. CONCLUSIONS: The cervical spine is forced to move from the lower vertebrae during rear-end collisions. This motion completely differs from normal extension motion and is probably related to the injury mechanism.

Accidents, Traffic↗

[Multiple myeloma with a solitary osteosclerotic legion on seventh cervical vertebra].

The osseous manifestation of multiple myeloma is well known as the osteolytic or osteoporotic feature. On the other hand, there are rare cases of general osteosclerotic manifestation as myeloma variants. We report a case of multiple myeloma with solitary osteosclerotic legion in the cervical vertebra. A 60-year-old-man was admitted with paralysis of both arms. The cervical roentogenogram showed the osteosclerotic change of the seventh cervical vertebra. The pathological study of surgical bone biopsy from the vertebra revealed osseous and severe fibrotic change and accumulation of plasma cells in the residual bone marrow. Clusters of plasma cells were also observed in the bone marrow of ileac bone. In addition, IgG-lambda type M protein was seen in the serum. Therefore we diagnosed this case as the osteosclerotic multiple myeloma. We then analyzed the cytokines known to influence bone formation, and found that the bone marrow serum TGF-beta and PDGF levels were increased compared with normal control. These results may suggest that the preferential increase of osteosclerotic cytokines caused the osteosclerotic changes of bone marrow.

Cervical Vertebrae↗

[Urinary malformations in synostoses of the cervical vertebrae (Klippel-Feil syndrome). Apropos of 35 cases].

A study of 35 cases of congenital fusion of the cervical vertebrae demonstrated the high incidence of its association with urinary anomalies (52 per cent). More than half of these cases concerned unilateral kidney defects. The urinary anomalies are normally asymptomatic, but there is always the risk of chronic renal failure, and preventive surgery may be necessary. It is therefore advisable to make a systematic practice of obtaining ultrasound examinations and intravenous urograms. There are many other possible associated anomalies, which are often the first to be noted and lead to the discovery of the vertebral and urinary malformations. The authors define Klippel-Feil syndrome as the synostosis of two or more cervical vertebrae.

Female↗

[A case of advanced colon cancer with metastases to both para-aortic lymph nodes and cervical vertebrae effectively treated by TS-1 therapy].

The patient was a 68-year-old woman who had cecal cancer with para-aortic lymph node metastases. Ileocecal resection was performed palliatively. Since metastasis to cervical vertebrae was detected after the operation, she received radiation therapy of 14 Gy to improve neck pain. Chemotherapy with TS-1 (80 mg/day) was started on an outpatient basis (4 weeks administration followed by a 2-week drug-free period). After 4 courses of this chemotherapy, metastases to both para-aortic lymph nodes and cervical vertebrae were remarkably reduced on CT and PET. Throughout the period of treatment, there was no adverse effect and this treatment has been maintained. In conclusion, this case seems significant from the viewpoint of achieving a partial response to TS-1 and maintaining a high quality of life. Moreover,we identified the presence of TS and DPD using an immunohistochemical staining technique. The primary tumor was positive for DPD stain test and negative for TS stain test. It was suggested that this cancer especially would respond to TS-1 chemotherapy.

Adenocarcinoma↗

Morphology of the cervical vertebrae in two caucasian ethnic groups.

A morphometric study of the cervical vertebrae was carried out on 63 Italian skeletons and 58 Asiatic Indian skeletons. The results indicate that there are considerable differences in the vertebral dimensions between ethnic groups of the same racial type. In a high proportion of both groups the mean sagittal diameter was less than 12 mm, which contradicts current opinion that this is the dividing line between the normal and the stenotic canal.

Adult↗

Early anterior decompression and fusion for crush fractures of cervical vertebrae.

From 1965 to 1991, 273 patients with crush fractures of cervical vertebrae were treated. They were sustained by young people in diving accidents, road accidents, or falls from a height. Spinal cord involvement with a varied degree of tetraplegia was usually present. The results of management by nonoperative or operative means have been compared. There has been neurological improvement in 14% of nonoperative and 44% of operative cases. Early surgical decompression by an anterior approach with stabilization by a bone graft is advocated to improve outcome and reduce the time in hospital.

Activities of Daily Living↗